Abstract:
:Topical anesthetic agents have increased in number, formulations, and applications because of their efficacy and generally mild side effect profile. To date, there have been no reports of immediate vesicular eruption as a result of topical application of lidocaine or tetracaine. Two cases and a brief review of the literature are presented. We report the cases of two patients who presented for ablative laser therapy. Immediately after application of 23% lidocaine and 7% tetracaine mixed in an ointment base, the patients developed a diffuse eruption of vesicles and bullae on a well-demarcated erythematous base. The patients' lesions resolved after <1 week with gentle skin care. One patient developed macules of postinflammatory hyperpigmentation which faded over 2 months. One patient chose to cancel his laser therapy because of concerns over reproducing this adverse reaction, while the second will proceed using a different topical anesthetic agent. While topical anesthetic agents should generally be considered safe, they are not without risks. These cases illustrate a previously unreported adverse event. Clinicians should be vigilant for this and other adverse drug reactions to commonly used topical anesthetics like lidocaine and tetracaine.
journal_name
J Cosmet Dermatoljournal_title
Journal of cosmetic dermatologyauthors
Vij A,Markus Rdoi
10.1111/j.1473-2165.2011.00576.xsubject
Has Abstractpub_date
2011-12-01 00:00:00pages
307-10issue
4eissn
1473-2130issn
1473-2165journal_volume
10pub_type
信件abstract:BACKGROUND AND OBJECTIVE:Topical aminophylline, caffeine, yohimbe, l-carnitine, and gotu kola (Centella asiatica) may aid in reducing body fat. Lipoxyderm™ contains these ingredients and was used to test if fat loss of the thigh, in conjunction with a low intensity exercise program and restricted calorie intake, was en...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,随机对照试验
doi:10.1111/jocd.12801
更新日期:2019-08-01 00:00:00
abstract::Hydroquinone (HQ) has been used since the 1950s in commercially available over-the-counter skin lightener products and since the 1960s as a commercially available medical product. It is also used in cosmetic products such as hair dyes and products for coating finger nails. Beginning in 2001, HQ is no longer authorized...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1473-2165.2006.00253.x
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND:Dietary or supplementary intake of nutrients and other ingredients positively affects skin appearance. AIMS:Evaluate a multicomponent nutritional supplement on photoaged skin. PATIENTS/METHODS:This multicenter, double-blind, placebo-controlled trial randomized healthy 35- to 65-year-old women with Fitzpatr...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/jocd.12290
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Skin dryness and an accelerated fragmentation of the collagen network in the dermis are hallmarks of skin aging. Nutrition is a key factor influencing skin health and consequently its appearance. A wide range of dietary supplements is offered to improve skin health. Collagen peptides are used as a bioactive ...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,随机对照试验
doi:10.1111/jocd.12174
更新日期:2015-12-01 00:00:00
abstract::Moisturizers are used on large body surfaces to maintain the smoothness of the skin and to break the dry-skin cycle. Many healthcare professionals and patients overlook the importance of moisturizers and do not consider them to be 'active' treatments. However, evidence from clinical and experimental studies shows that...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/j.1473-2130.2004.00062.x
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:Pigmentary disorders are commonly seen in dermatology practice and can have a negative psychosocial impact on patients. OBJECTIVE:This study aims to examine the prevalence of pigmentary disorders and their level of psychological and physical impact on patients. METHODS:A prospective cohort study involved a...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/j.1473-2165.2008.00384.x
更新日期:2008-09-01 00:00:00
abstract::Chronic headaches are common and can have a significant effect on quality of life. Approved treatment options are vast and include the use botulinum toxin injections. The objective of this study is to evaluate the effects of purely cosmetic onabotulinumtoxinA (BOTOX) injections on the frequency and severity of chronic...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12098
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:The intracellular form of action of retinoids requires these agents to reach deeper layers of the skin with viable cells to ensure therapeutic efficiency. However, studies on swine skin models show that some retinoids have low skin permeability. Thus, the association of innovative formulations with technolog...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13826
更新日期:2020-11-03 00:00:00
abstract:BACKGROUND:Atopic dermatitis (AD) is an inflammatory pruritic chronic dermatosis involving the alarmin thymic stromal lymphopoietin (TSLP), which is directly implicated in AD pruritus. AIMS:To evaluate the efficacy of Tambourissa trichophylla leaf extract (TTLE) titrated in polyphenols and 18β-glycyrrhetinic acid (GA)...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13515
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:To investigate the effectiveness of the posterior temporal supraSMAS minimally invasive lifting technique and compared it to experiments performed in fresh human body donors by applying skin vector displacement measurement technology. MATERIALS AND METHODS:A total of 15 patients (14 females/1 male) with a m...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12722
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Facial telangiectasia is one of the common skin vascular lesions characterized by dilated cutaneous vasculatures. The variety of diameters and difference in depths of lesional blood vessels are the major challenges for effective treatments for Facial telangiectasia. AIMS:To compare the efficacy and safety p...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13179
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Blue light from electronic devices enriched with a peak at 456 nm affects circadian rhythm and antioxidant balance of skin, necessitating the study of photoprotection against the 456-nm blue light. AIMS:This study aims to report that blue light (456 nm) can cause skin pigmentation and proposes a new clinica...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13508
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:This work presents the first report that A. rugosa could have tyrosinase and melanogenesis inhibition and that its activities also be improved by fermentation with Lactobacillus rhamnosus and Lactobacillus paracasei. It was found that the tyrosinase and melanogenesis inhibition was correlated with antioxidan...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12264
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Psoriasis is an inflammatory disease that is mostly immune-derived. It causes proliferation of skin cells, forming plaques. Psoriasis etiology is unknown. It might be multifactorial. AIMS:This work aimed to study Smad7 expression in psoriasis vulgaris patients in comparison with normal skin. PATIENTS/METHO...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13425
更新日期:2020-12-01 00:00:00
abstract::To review indexed literature concerning adverse ocular effects of the most common aesthetic facial procedures (light-emitting therapy, dermal fillers injection, and botulinum toxin). Literature search using three online databases - PubMed, SciELO, and Capes - selecting case reports, series of cases and reviews, with n...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
doi:10.1111/jocd.12141
更新日期:2015-06-01 00:00:00
abstract::The authors report the case of a 58-year-old woman presenting with "puffiness" in her lower eyelids persisting for approximately 5 years. While dark, puffy eyelid circles following hyaluronic acid placement periorbitally are not uncommon, what is so unusual in our case is that it was noted 5 years after treatment with...
journal_title:Journal of cosmetic dermatology
pub_type: 信件
doi:10.1111/j.1473-2165.2012.00622.x
更新日期:2012-09-01 00:00:00
abstract::The nail is the largest skin appendage. In addition to its important physiological and sensory functions, it is also of great esthetic importance. Complaints of brittle or soft nails are frequent, particularly among women. Innumerable preparations claiming to improve the nail quality are being sold; however, most have...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1473-2165.2006.00232.x
更新日期:2006-03-01 00:00:00
abstract:BACKGROUND:Riehl's melanosis is a chronic, refractory disorder, which can adversely affect patient's quality of life. Intense pulse light, neodymium-doped yttrium aluminum garnet laser, hydroquinone, tranexamic acid have been reported to treat this disease, but there have been few reports on the effectiveness of other ...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13153
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Application of radiofrequency (RF) energy with microneedles to facial skin shown to promote skin renewal. AIM:To evaluate the safety and efficacy of the VoluDerm technology with 100 ultra-thin electrodes gen100 tip for improvement of skin texture and wrinkles. METHODS:A prospective, open-label, intra-indiv...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13239
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Rosacea is a chronic skin condition that typically affects the face and it results in redness and inflammation. The main risk factors of this disease are Demodex folliculorum, living in the pilosebaceous units. AIMS:To evaluate the efficacy and safty of permethrin 2.5% in combination with tea tree oil (TTO)...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13177
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Hair transplant surgery using follicular unit extraction technique (FUE) is a common surgical procedure for the treatment of severe hair loss. Blood-derived autologous growth factors have also proved to promote hair regeneration in patients with different types of alopecia. AIMS:The aim of this study was to...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12446
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Hypertrophic scarring is seen regularly. Tissue penetration of laser energy into hypertrophic scars using computer defaults from some lasers may be insufficient and penetration not enough. We have developed a treatment with an interrupted laser "drilling" by the Ultrapulse CO2 (Manual Fractiona...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12334
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Androgenetic alopecia (AGA) is the most common cause of alopecia in men. In the literature, although there are in vitro studies investigating the relationship between oxidative stress and AGA, any in vivo study does not exist. AIM:Our aim was to evaluate the oxidative stress status in male patients with ear...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12300
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Under specific light illumination, particularly ultraviolet radiation (UVR), the skin produces both specular light reflectance and, possibly, specific fluorescent emission. A quenching effect of fluorescence is observed following the application of sunscreens active against UVA radiations. AIMS:To assess no...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12169
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:Xanthelasma palpebrarum (XP) is the most common type of cutaneous xanthoma and has been treated with intralesional injection of pingyangmycin effectively. However, bleomycin, which has the same effect in antitumor activity as pingyangmycin, has not been applied in the treatment of XP. AIMS:To explore and as...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13258
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Adult dermatological out patients have a 40% prevalence of psychiatric co-morbidity. If psychiatric co-morbidity is unrecognized, undetected and untreated, the consequences may be fatal. Acne is the most common skin disorder of the second and third decades of life. Acne and its treatments may cause depressio...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1473-2165.2002.00057.x
更新日期:2002-12-01 00:00:00
abstract::Nevus lipomatosus cutaneous superficialis (NLCS) is an uncommon lesion characterized by ectopic adipose tissue in the dermis and can be generalized or localized. It presents as a soft skin colored to yellowish papules or cerebriform plaques occurring usually on the buttock or thigh in a segment distribution. We report...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12327
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Androgenetic alopecia is a common cosmetic hair disorder, resulting from interplay of genetic, endocrine, and aging factors leading to a patterned follicular miniaturization. Microinflammation seems to be a potential active player in this process. AIMS:To study the histopathological and ultrastructural chan...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/j.1473-2165.2009.00439.x
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:To assess the effectiveness of injection of autologous keratin gel and fibroblast for neck aging as soft tissue filler. MATERIALS AND METHODS:Totally 30 volunteers received treatment of autologous keratin and fibroblast for neck wrinkles and 5 of them received hyaluronic acid (HA) treatment as control. Clini...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,随机对照试验
doi:10.1111/jocd.12438
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Vitiligo is one of the commonest pigmentary disorders characterized by destruction of melanocytes. AIM:To evaluate the efficacy of topical bimatoprost ophthalmic solution in stable facial vitiligo. MATERIAL AND METHODS:Eight cases of stable facial vitiligo were treated with bimatoprost 0.03% ophthalmic sol...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12443
更新日期:2018-06-01 00:00:00