Abstract：
BACKGROUND:Rosacea is a chronic skin condition that typically affects the face and it results in redness and inflammation. The main risk factors of this disease are Demodex folliculorum, living in the pilosebaceous units. AIMS:To evaluate the efficacy and safty of permethrin 2.5% in combination with tea tree oil (TTO) topical gel versus placebo on Demodex density (Dd) and clinical manifestation using standard skin surface biopsy (SSSB) in rosacea patients. PATIENT/METHODS:In this double-blind, randomized clinical trial, 47 papulopustular rosacea patients were enrolled, with 35 patients finishing the 12 weeks of treatment. Each patient used permethrin 2.5% with TTO on one side of the face and a placebo on the other, twice daily for 12 weeks. SSSB, photography and clinical rosacea scores according to National Rosacea Society, as well as adverse drug reaction (ADRs) were reported at the baseline, 2nd, 5th, 8th, and 12th weeks. RESULTS:A total of 47 patients were enrolled with papulopustular rosacea, and 35 patients finished the study. The effects of permethrin 2.5% with TTO gel on mite density were significant at week 5, 8, 12 (P value = .001). Clinical features and global assessments showed papules, pustules and nontransient erythema had improvement in drug group after 12 weeks (P values <.05). The improvement of burning and stinging and dry appearance was greater than the placebo gel (P value <.05). Itching in placebo group was significantly more than other group (P value = .002). CONCLUSION:Administration of permethrin 2.5% with TTO gel demonstrated good efficacy and safety in rosacea. This topical gel inhibited the inflammatory effects of rosacea and reduced Demodex mite.
journal_name
J Cosmet Dermatoljournal_title
Journal of cosmetic dermatologyauthors
Ebneyamin E,Mansouri P,Rajabi M,Qomi M,Asgharian R,Azizian Zdoi
10.1111/jocd.13177subject
Has Abstractpub_date
2020-06-01 00:00:00pages
1426-1431issue
6eissn
1473-2130issn
1473-2165journal_volume
19pub_type
杂志文章abstract：BACKGROUND:Intradermal application of hyaluronic acid (HA) in varying chain length and cross-linking density is used routinely for hydrodynamic volume replacement of the extracellular matrix to reduce the clinical effects of aging. OBJECTIVES:In vitro data show that via receptors of the hyaladherin group hyaluronic ac...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12024
更新日期：2013-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Hypertrophic scarring is seen regularly. Tissue penetration of laser energy into hypertrophic scars using computer defaults from some lasers may be insufficient and penetration not enough. We have developed a treatment with an interrupted laser "drilling" by the Ultrapulse CO2 (Manual Fractiona...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12334
更新日期：2017-06-01 00:00:00
abstract：:Cutaneous hypermelanoses are frequently encountered conditions that can have severe adverse psychosocial and emotional effects on affected patients. Melasma, postinflammatory hyperpigmentation, drug-induced pigmentation, and erythema dischromicum perstans are among the most common cutaneous disorders leading to acquir...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/j.1473-2165.2006.00276.x
更新日期：2006-12-01 00:00:00
abstract：BACKGROUND:Hair plays a significant role in shaping the appearance of an individual. Loss of hair can lead to serious effects on social esteem of an individual. The most common cause of hair loss is Androgenetic Alopecia (AGA).This hereditary disorder followed a specific pattern causing progressive thinning of hair in ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13398
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:Some moisturizing formulations can help restore and maintain the barrier function of the skin. OBJECTIVES:This study was designed to assess the hydration potential of three lamellar moisturizers relative to a control (nonlamellar) moisturizer. METHODS:Healthy adults aged 18 to 65 years with self-reported s...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13361
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:Spasmodic senile entropion (SE) is characterized by the inward turning of the eyelid. SE typically occurs spontaneously, but sometimes after ocular surgery. As of today, it is still lacking a gold standard technique. AIMS:To report the results of 11 cases of involutional entropion of the lower lid successfu...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/jocd.12210
更新日期：2016-06-01 00:00:00
abstract：BACKGROUND:The plant species Anemarrhena asphodeloides has commonly been used for health and therapeutic purposes. Timosaponin B-II, which is present at a high concentration in A asphodeloides, was found to enhance the immune and anti-inflammatory responses of human bodies. AIMS:To evaluate benefits of a timosaponin B...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13672
更新日期：2020-08-11 00:00:00
abstract：BACKGROUND:The demand for personalized skin care is increasing rapidly in recent years. In order to provide suitable products for different customers, an accurate assessment of the skin condition is required. It is necessary to establish a remote and convenient method for quantifying skin condition. MATERIALS AND METH...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13576
更新日期：2021-02-01 00:00:00
abstract：INTRODUCTION:Tattooing is a very popular form of body modification among young people. However, this kind of procedure entails the risk of various health complications. The objective of the study was to evaluate the students' knowledge about contraindications, complications, and health risks that skin tattooing may cau...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/jocd.12479
更新日期：2018-02-01 00:00:00
abstract：:Skin resurfacing has been a part of cosmetic dermatology for more than two decades now, and most of it has been ablative with traditional aggressive lasers including the CO(2) and erbium. The last few years have seen a revolutionary change with the invention of nonablative lasers for skin tightening. Fractional resurf...
journal_title：Journal of cosmetic dermatology
pub_type： 历史文章,杂志文章,评审
doi：10.1111/j.1473-2165.2010.00528.x
更新日期：2010-12-01 00:00:00
abstract：BACKGROUND:Port Wine Stain (PWS) is a congenital capillary malformation. Although multiple treatments are required, the gold standard treatment for PWS is Pulsed Dye Laser (PDL). Given its anti-angiogenic effects, sirolimus can be considered as an adjuvant to PDL in PWS. AIM:To evaluate the efficacy and safety of topi...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13867
更新日期：2020-11-29 00:00:00
abstract：:Recently, both doctors and patients pay particular attention to aesthetic medical services quality and efficacy of aesthetic adjustment implemented. It is essential to ensure research, analysis, and improving of botulinum toxin therapy quality and provide patients' orientation on the adjustment schedule, which include...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13584
更新日期：2021-02-01 00:00:00
abstract：BACKGROUND:Gender-related price inequalities for over-the-counter dermatologic products such as shampoos and conditioners, razors, deodorants, and lotions remain prevalent in the marketplace. This trend has also been found to apply to topical minoxidil, a common treatment for male and female pattern hair loss. OBJECTI...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12954
更新日期：2019-12-01 00:00:00
abstract：:In contrast to the female breast the male breast has gained much less attention by aesthetic surgery and cosmetic dermatology. In this review a focus on minimally invasive procedures to correct aesthetic problems of male breast are discussed. The major indications are gynecomastia, breast asymmetry, and body sculpturi...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/j.1473-2165.2011.00548.x
更新日期：2011-06-01 00:00:00
abstract：:Forced air cooling is a well-established technique that protects the epidermis during laser heating of deeper structures, thereby allowing for increased laser fluences. The goal of this prospective study was to identify whether an elevation in ambient room temperature influences the efficacy of forced air cooling. Ski...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2165.2007.00327.x
更新日期：2007-09-01 00:00:00
abstract：BACKGROUND:The main application of hyaluronic acid filling, in esthetic medicine, is the augmentation of soft tissues. The carbon dioxide therapy, instead, improves quality and elasticity of the dermis and increases the oxygen release to the tissue through an enhancing of the Bohr's effect. The aim of the study was to ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/jocd.12213
更新日期：2016-06-01 00:00:00
abstract：BACKGROUND:The aging process affects all organs of the body, but the skin is the most visible indicator with a great psychosocial impact. As a consequence, many skin anti-aging strategies have been developed to minimize, postpone, and even reverse the aging process. Growth factors have been widely studied in skin wound...
journal_title：Journal of cosmetic dermatology
pub_type： 临床试验,杂志文章
doi：10.1111/jocd.12771
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVE:To assess the effectiveness of injection of autologous keratin gel and fibroblast for neck aging as soft tissue filler. MATERIALS AND METHODS:Totally 30 volunteers received treatment of autologous keratin and fibroblast for neck wrinkles and 5 of them received hyaluronic acid (HA) treatment as control. Clini...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/jocd.12438
更新日期：2018-08-01 00:00:00
abstract：BACKGROUND:Pigmentary disorders are commonly seen in dermatology practice and can have a negative psychosocial impact on patients. OBJECTIVE:This study aims to examine the prevalence of pigmentary disorders and their level of psychological and physical impact on patients. METHODS:A prospective cohort study involved a...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2165.2008.00384.x
更新日期：2008-09-01 00:00:00
abstract：BACKGROUND:Glycolic acid (GA) is an effective way of reversing the signs of age and photodamage. GA enhances desquamation of the stratum corneum and induces biological responses that can help restore skin's integrity. GA can, however, cause irritation, especially when its concentration is high, and its pH is low. Thus,...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13570
更新日期：2021-02-01 00:00:00
abstract：OBJECTIVE:To explore the influence of hyperbaric oxygen on scar formation in rabbit ears. METHODS:A total of 20 New Zealand rabbits were selected to establish the hypertrophic scar model on the ears. The rabbits were randomly divided into control group and experimental group (7d, 14d, 21d, and 28d group according to d...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12468
更新日期：2018-12-01 00:00:00
abstract：:Hydroquinone has been used for decades as a skin lightening agent. Since January 1, 2001, its use in cosmetics has been banned. This ban is as a result of mid-term effects such as leukoderma-en-confetti/occupational vitiligo and exogenous ochronosis. However, a recent literature search on hydroquinone as a skin lighte...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2165.2005.40202.x
更新日期：2005-06-01 00:00:00
abstract：BACKGROUND:Under specific light illumination, particularly ultraviolet radiation (UVR), the skin produces both specular light reflectance and, possibly, specific fluorescent emission. A quenching effect of fluorescence is observed following the application of sunscreens active against UVA radiations. AIMS:To assess no...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12169
更新日期：2016-03-01 00:00:00
abstract：INTRODUCTION:Fractional carbon dioxide (FrCO2 ) laser is effective for atrophic acne scar treatment, but unavoidable downtime. Meanwhile, postoperative topical steroid decreases the downtime, yet still possibly increases other steroid side effects. OBJECTIVE:To evaluate the efficacy and safety of moisturizer containin...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/jocd.12951
更新日期：2019-12-01 00:00:00
abstract：CONTEXT:Subcision is a simple surgical method that can be effective in treatment of acne scars. AIMS:This study was conducted to evaluate and compare the two methods of Nokor needle and blunt blade (BB) subcision in treatment of acne scars. SETTINGS AND DESIGN:This clinical trial study was conducted on 28 patients wi...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12981
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:Pediatric hypertrophic burn scars are challenging to treat due to their widespread nature and pain associated with the treatment. Intralesional triamcinolone acetonide (TAC) injection with or without 5-fluorouracil (5FU) is considered first-line treatment for severe hypertrophic scars. The pain associated wi...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13192
更新日期：2020-01-01 00:00:00
abstract：:Psoriasis is a chronic, immune-mediated disease that has a major negative impact on a patient's quality of life. Although several literature reviews indicate that skin microbiota may play an important role in the development and regulation of the immune and inflammatory response of psoriasis, few clinical studies are ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/jocd.13752
更新日期：2020-09-30 00:00:00
abstract：BACKGROUND:Palmar hyperhidrosis (PH) can produce social and occupational difficulties and reduce the quality of life of those who suffer from this kind of problem. When dealing with focal hyperhidrosis, the patients' attitudes and their subjective approaches regarding the process may influence the objective evaluation ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2165.2005.00304.x
更新日期：2005-09-01 00:00:00
abstract：BACKGROUND:Hair transplant procedure is a surgical procedure which affects the sensitivity of the scalp. OBJECTIVES:To compare scalp two-point discrimination (2PD) values in healthy controls and patients who had hair transplant surgery. PATIENTS/METHODS:The comparative study was conducted in 25 healthy individuals an...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13326
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:Human skin aging is caused by several factors, such as UV irradiation, stress, hormone, and pollution. Wrinkle formation and skin pigmentation are representative features of skin aging. Although EGF and arbutin are used as anti-wrinkle and skin whitening agents, respectively, they have adverse effects on ski...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12671
更新日期：2019-02-01 00:00:00
