Abstract：
BACKGROUND:Hair plays a significant role in shaping the appearance of an individual. Loss of hair can lead to serious effects on social esteem of an individual. The most common cause of hair loss is Androgenetic Alopecia (AGA).This hereditary disorder followed a specific pattern causing progressive thinning of hair in both Men and Women. AIMS:The aim of the current study is to compare and evaluate the efficacy of QR678 therapy versus PRP in the treatment of Male Androgenetic Alopecia. Since QR678 and QR678 Neo have been found to be formulations equivalent in efficacy, the results would be the same with either formulation. METHODS:A prospective, comparative, single-blind study was carried out with 2 groups of 25 patients each. Intradermal injections of QR678 formulations and PRP were injected in group A and B respectively. Hair pull test, Video microscopic assessment, Global Photographic assessment was done and patient's subjective assessment was done through questionnaire at the end of the study. Results were evaluated after 6 months and follow up was done till 1 year. RESULTS:100% reduction in hair fall was noted at the end of 6 months in the QR678 group which was maintained for 1 year. Video microscopic evaluation showed that the hair density, terminal hair density, vellus hair density and shaft diameter were significantly better in QR678 group (P < .005) than the PRP group. Since QR678 and QR678 Neo formulatons are equivalent in efficacy, the results of tthis trial can be attributed to be the same, irrespective of the formulation used. CONCLUSION:The bioengineered formulation of QR678 proved to be more beneficial for Male Androgenetic Alopecia (Male pattern hair loss) compared to PRP. A comparative study between QR678 and PRP with long term follow-up will widen our spectra of knowledge.
journal_name
J Cosmet Dermatoljournal_title
Journal of cosmetic dermatologyauthors
Kapoor R,Shome D,Vadera S,Ram MSdoi
10.1111/jocd.13398subject
Has Abstractpub_date
2020-11-01 00:00:00pages
2877-2885issue
11eissn
1473-2130issn
1473-2165journal_volume
19pub_type
杂志文章abstract：:Cutaneous hypermelanoses are frequently encountered conditions that can have severe adverse psychosocial and emotional effects on affected patients. Melasma, postinflammatory hyperpigmentation, drug-induced pigmentation, and erythema dischromicum perstans are among the most common cutaneous disorders leading to acquir...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/j.1473-2165.2006.00276.x
更新日期：2006-12-01 00:00:00
abstract：BACKGROUND:Facial dermatitis can result from various conditions, some of which are of a chronic and relapsing nature. The use of topical corticosteroid therapy may lead to additional adverse effects. OBJECTIVE:To compare the efficacy of moisturizer containing 4-t-butylcyclohexanol, which acts as a sensitivity regulato...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/jocd.12499
更新日期：2018-12-01 00:00:00
abstract：INTRODUCTION:There are no evidence-based data how to predict response to therapy in patients with alopecia areata. AIM:The assessment of the predictive value of trichoscopy for the therapeutic outcome in patients with alopecia areata. METHODS:A total of 65 patients with patchy alopecia areata were included into the s...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13064
更新日期：2020-03-01 00:00:00
abstract：:The stratum corneum (SC) (i.e., the outermost layer of human skin) is a complex and paradoxical tissue composed of corneocytes and a matrix of intercellular lipids playing an essential role as the skin's protective barrier. The first paradox of SC is its dual nature. It is composed of nondividing (dead) cells embedded...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/j.1473-2165.2008.00379.x
更新日期：2008-06-01 00:00:00
abstract：:The popularity of tattoos in the today's society brings with it a significant increase of the incidence of associated cutaneous reactions. Among the several complications that may occur after a tattooing procedure, allergic and photo-allergic reactions, infections, and Koebner phenomenon are the most common ones obser...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13548
更新日期：2021-02-01 00:00:00
abstract：:Forced air cooling is a well-established technique that protects the epidermis during laser heating of deeper structures, thereby allowing for increased laser fluences. The goal of this prospective study was to identify whether an elevation in ambient room temperature influences the efficacy of forced air cooling. Ski...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2165.2007.00327.x
更新日期：2007-09-01 00:00:00
abstract：BACKGROUND:Ultraviolet B (UVB) irradiation is viewed as the main factor of skin aging, associated with acceleration of elastin, collagen degradation and expression of matrix metalloproteinases (MMPs). Apples are one of the most commonly eaten fruits in the world, and isoquercitrin is the main active ingredient in new b...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13903
更新日期：2020-12-23 00:00:00
abstract：BACKGROUND:Acne vulgaris is the most common dermatological condition encountered in adolescents. AIM:It was to determine the prevalence of acne vulgaris and its impact of the quality of life among adolescents attending secondary schools in Sohag Province, Upper Egypt. PATIENTS AND METHODS:This was a cross-sectional s...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12328
更新日期：2017-09-01 00:00:00
abstract：:Chemical peeling, also known as chemoexfoliation or dermapeeling, is performed to improve the skin's appearance as it reduces the wrinkles caused by aging and the features of photoaged skin. Although the best results are obtained with deep peels, the medium-depth peels allow to obtain excellent results without the dan...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2165.2005.40213.x
更新日期：2005-06-01 00:00:00
abstract：BACKGROUND:Melasma is an acquired disorder of symmetrical hyperpigmentation. Several treatment methods are available for patients with melasma, including topical compounds, broad-spectrum photoprotection, camouflage, chemical peels, and laser and light therapies which represent potentially promising options for patient...
journal_title：Journal of cosmetic dermatology
pub_type： 临床试验,杂志文章
doi：10.1111/jocd.12751
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:Psoriasis is an inflammatory disease that is mostly immune-derived. It causes proliferation of skin cells, forming plaques. Psoriasis etiology is unknown. It might be multifactorial. AIMS:This work aimed to study Smad7 expression in psoriasis vulgaris patients in comparison with normal skin. PATIENTS/METHO...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13425
更新日期：2020-12-01 00:00:00
abstract：BACKGROUND:Acne vulgaris is an inflammatory disorder with a profound heterogenous aetio-pathophysiology. ACE gene I/D polymorphism affects angiotensin-converting enzyme activities that play a role in inflammation. However, there are no molecular genetic studies investigating the contribution of ACE gene insertion/delet...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12937
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:As the face is known for its extreme variation in vascular anatomy and the number of filler-associated complications due to intra-arterial injection is increasing, we are in need of a method to visualize anyone's individual arterial anatomy of the face in a completely harmless way. AIMS:The different medica...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/jocd.13477
更新日期：2021-02-01 00:00:00
abstract：BACKGROUND:Rosacea is a chronic skin condition that typically affects the face and it results in redness and inflammation. The main risk factors of this disease are Demodex folliculorum, living in the pilosebaceous units. AIMS:To evaluate the efficacy and safty of permethrin 2.5% in combination with tea tree oil (TTO)...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13177
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:Spitzoid melanoma is one of the rare subtypes of melanoma, whose clinical and pathological characteristics have yet to be understood. OBJECTIVE:Understanding the histopathologic features and behavior characteristics of Spitzoid cutaneous melanoma. METHODS:A total number of 11 Turkish Caucasian patients wit...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12958
更新日期：2019-12-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy and safety associated with use of a 589-nm solid-state laser for treatment of facial erythema. METHODS:A prospective, IRB-approved study was conducted. Participants who were interested in treatment for facial erythema were recruited. They received four monthly treatments with the 589...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12742
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:Dietary or supplementary intake of nutrients and other ingredients positively affects skin appearance. AIMS:Evaluate a multicomponent nutritional supplement on photoaged skin. PATIENTS/METHODS:This multicenter, double-blind, placebo-controlled trial randomized healthy 35- to 65-year-old women with Fitzpatr...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1111/jocd.12290
更新日期：2017-03-01 00:00:00
abstract：BACKGROUND:Recent studies have reported that the incidence of acne combined with rosacea is increasing. However, the clinical feature and inducing factor of these two diseases co-occurrence is remain unclear. AIMS:This study aims to investigate the classification and severity of female patients combining with acne and...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13762
更新日期：2020-10-06 00:00:00
abstract：:Recently, both doctors and patients pay particular attention to aesthetic medical services quality and efficacy of aesthetic adjustment implemented. It is essential to ensure research, analysis, and improving of botulinum toxin therapy quality and provide patients' orientation on the adjustment schedule, which include...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13584
更新日期：2021-02-01 00:00:00
abstract：BACKGROUND:The intracellular form of action of retinoids requires these agents to reach deeper layers of the skin with viable cells to ensure therapeutic efficiency. However, studies on swine skin models show that some retinoids have low skin permeability. Thus, the association of innovative formulations with technolog...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13826
更新日期：2020-11-03 00:00:00
abstract：BACKGROUND:Lip enhancement using fillers improves appearance by increasing fullness, enhancing lip definition, and reducing fine lines and wrinkles around the lips. AIMS:To investigate a 24 mg/mL hyaluronic acid (HA) with pre-incorporated lidocaine gel for lip definition and enhancement, medium-deep lines, and oral co...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2165.2010.00539.x
更新日期：2011-03-01 00:00:00
abstract：:Chronic headaches are common and can have a significant effect on quality of life. Approved treatment options are vast and include the use botulinum toxin injections. The objective of this study is to evaluate the effects of purely cosmetic onabotulinumtoxinA (BOTOX) injections on the frequency and severity of chronic...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12098
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND:Acne vulgaris is the most common inflammatory sebaceous gland disorder in young adults. The resistant strains of Propionibacterium acnes (P. acnes) are of increasing concern in the treatment of acne. OBJECTIVES:To evaluate the efficacy of 0.5% topical mangosteen extract in nanoparticle loaded gel (containin...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12856
更新日期：2019-01-27 00:00:00
abstract：:Soap is the most useful things which we use our everyday life in various cleansing and cosmetics purposes. Jatropha oil is nonedible oil which has more benefits to soap making. It has also cosmetics and medicinal properties. But the presence of toxic Phorbol esters in Jatropha oil is the main constrains to use it. So ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/jocd.12209
更新日期：2016-06-01 00:00:00
abstract：BACKGROUND:Onychomycosis is a fungal infection of the nail, affecting 5.5% of the population. Individuals affected by this disease experience increased anxiety about this disorder and a decreased quality of life. There are multiple available treatments across the globe, leading people to search online for information o...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13585
更新日期：2020-07-02 00:00:00
abstract：INTRODUCTION:Tattooing is a very popular form of body modification among young people. However, this kind of procedure entails the risk of various health complications. The objective of the study was to evaluate the students' knowledge about contraindications, complications, and health risks that skin tattooing may cau...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/jocd.12479
更新日期：2018-02-01 00:00:00
abstract：:Topical anesthetic agents have increased in number, formulations, and applications because of their efficacy and generally mild side effect profile. To date, there have been no reports of immediate vesicular eruption as a result of topical application of lidocaine or tetracaine. Two cases and a brief review of the lit...
journal_title：Journal of cosmetic dermatology
pub_type： 信件
doi：10.1111/j.1473-2165.2011.00576.x
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:Treating the lower face with neuromodulators and targeting the masseter muscle can reduce masseteric hypertrophy but can also change the facial shape. A novel observation after the treatment of the masseter muscle with incobotulinumtoxin Type A was the increase in temporal volume. AIM:Objectively assess tem...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13434
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:Welders are normally at risk of skin cancer due to continuous contact with natural ultraviolet rays and welding radiation. Protective behaviors against the radiations are the most fundamental measures taken to prevent skin cancer in these individuals. AIMS:This research aimed to evaluate the factors affecti...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13092
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:Anti-aging effects of high concentrations of salicylic acid (SA) peels are commonly known. Like all acids, SA can produce somatosensory and visible irritation to the skin and as such may be unsuitable for subjects with sensitive skin. AIMS:To provide evidence that sodium salicylate (SS) obtained from neutra...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2165.2010.00506.x
更新日期：2010-09-01 00:00:00
