Abstract:
:Many cosmetic companies utilize in vitro gene array studies to display significant stimulation or inhibition of various human skin biomarkers to validate in vivo actions that are reported to enhance dermal health. This follows the central dogma of DNA-to-RNA results in protein expression; however, gene and protein expressions do not usually correlate. Unless both gene and protein expressions are quantified which require further investigational time and investment. Where data are available, this short commentary displays the in vitro comparison of four human skin biomarkers for the gene and protein expressions of the stimulation of collagen type I and elastin and the inhibition of matrix metalloproteinases 1 and 3, when equol was tested. The results demonstrate a good correspondence between gene and protein expressions for the human skin biomarkers tested.
journal_name
J Cosmet Dermatoljournal_title
Journal of cosmetic dermatologyauthors
Lephart EDdoi
10.1111/jocd.12362subject
Has Abstractpub_date
2018-04-01 00:00:00pages
244-245issue
2eissn
1473-2130issn
1473-2165journal_volume
17pub_type
杂志文章abstract:BACKGROUND:Inflammation and postinflammatory hyperpigmentation (PIH) are two adverse side effects of ablative fractional CO2 laser (ablative Fr CO2 ) treatment for both rejuvenation and acne scars. AIMS:To evaluate the efficacy of fusidic acid cream versus erythromycin ointment as postoperative therapy in patients who...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13735
更新日期:2020-09-26 00:00:00
abstract:BACKGROUND:Lip enhancement using fillers improves appearance by increasing fullness, enhancing lip definition, and reducing fine lines and wrinkles around the lips. AIMS:To investigate a 24 mg/mL hyaluronic acid (HA) with pre-incorporated lidocaine gel for lip definition and enhancement, medium-deep lines, and oral co...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/j.1473-2165.2010.00539.x
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Phenolic and flavonoid compounds found in plants alleviate the photo-damaging skin conditions by playing a major role in skin rejuvenation. AIMS:The aim of the study was to explore the cosmeceutical effects of Cinnamomum tamala extract. OBJECTIVE:Recent research was aimed to quantify phenols and flavonoids...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13198
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Treating the lower face with neuromodulators and targeting the masseter muscle can reduce masseteric hypertrophy but can also change the facial shape. A novel observation after the treatment of the masseter muscle with incobotulinumtoxin Type A was the increase in temporal volume. AIM:Objectively assess tem...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13434
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Subjects seeking facial rejuvenation want the results to appear natural. Currently, however, there is no consensus definition of, or assessment scale for, "naturalness." AIMS:This open-label pilot study explored evaluation techniques and criteria to assess naturalness of facial movement and expression follo...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12961
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Human hair cuticle is always exposed to various stresses and then gradually lost in daily life. There are two typical patterns of cuticle damage: type L, where the cell membrane complex, the structure located between cuticle cells, is split and the cuticle lifts up, and type E, where the fragile substructure...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12129
更新日期:2015-03-01 00:00:00
abstract::Psoriasis is a chronic, immune-mediated disease that has a major negative impact on a patient's quality of life. Although several literature reviews indicate that skin microbiota may play an important role in the development and regulation of the immune and inflammatory response of psoriasis, few clinical studies are ...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
doi:10.1111/jocd.13752
更新日期:2020-09-30 00:00:00
abstract:BACKGROUND:There remains the need for more effective therapeutic options to treat acne vulgaris. Interest in light-based acne treatments has increased, but few randomized, controlled clinical trials assessing the value of photodynamic therapy (PDT) for acne have been reported. AIMS:We sought to examine the efficacy of...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1473-2165.2010.00483.x
更新日期:2010-03-01 00:00:00
abstract::The authors report the case of a 58-year-old woman presenting with "puffiness" in her lower eyelids persisting for approximately 5 years. While dark, puffy eyelid circles following hyaluronic acid placement periorbitally are not uncommon, what is so unusual in our case is that it was noted 5 years after treatment with...
journal_title:Journal of cosmetic dermatology
pub_type: 信件
doi:10.1111/j.1473-2165.2012.00622.x
更新日期:2012-09-01 00:00:00
abstract::Hydroquinone (HQ) has been used since the 1950s in commercially available over-the-counter skin lightener products and since the 1960s as a commercially available medical product. It is also used in cosmetic products such as hair dyes and products for coating finger nails. Beginning in 2001, HQ is no longer authorized...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1473-2165.2006.00253.x
更新日期:2006-09-01 00:00:00
abstract::Leg telangiectasia is more difficult to treat than facial telangiectasia. Investigations may be needed to elucidate the origin of the telangiectasia. In cases of venous insufficiency, investigation of venous haemodynamics is desirable. Treatment is primarily by sclerotherapy, including foam sclerotherapy. Light and la...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/j.1473-2130.2004.00044.x
更新日期:2003-04-01 00:00:00
abstract:BACKGROUND:Skin pH is an important parameter indicating the condition of the skin because imbalance can contribute to the development of skin problems and earlier aging. Individual skin pH depends on many factors such as hydration, sweating, sebum excretion, genetics, sex, and age. Additionally, it can be affected by e...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12303
更新日期:2017-12-01 00:00:00
abstract::A 23-year-old left-handed white male was referred with a complaint of brown discolouration of the fingernails of his left hand. He had been applying 4% hydroquinone cream to facial melasma. The discolouration began in winter and worsened in March and April. It resolved within 2 months of cessation of hydroquinone. The...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/j.1473-2130.2004.00085.x
更新日期:2003-07-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to evaluate the efficacy of tattoo removal treatments using the 1064-nm Q-switched (QS) Nd:YAG laser. BACKGROUND DATA:Today, QS lasers appear to be the most common, effective, and safest methods to treat unwanted markings. MATERIAL AND METHODS:A total of 64 patients with 75 unwanted...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12162
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Since air pollution is only one of many environmental stressors that can affect skin, it has been challenging to identify skin appearance or functional features profoundly affected by chronic exposure to traffic-derived air pollution. AIMS:The current population study focused on taxi drivers working in urba...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13194
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Numerous fillers can be used for midface revolumization. While rheological data, physiochemical properties, and durability measured in clinical studies can inform selection, direct comparisons between equal volumes of different fillers are lacking. AIMS:To compare aesthetic improvement achieved with 3 cc of...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13881
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:Ultraviolet (UV) radiation has been implicated in photoaging and various types of skin carcinomas. Although the human skin has evolved several defense mechanisms to survive the insults of actinic damage like keratinization, melanin pigmentation, etc., it is still subjected to the harmful effects of sunlight....
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/j.1473-2165.2007.00293.x
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:Skin care influences skin barrier function during the first postnatal weeks. Although the use of natural oils in preterms has been investigated, there are currently no data comparing the effect of sunflower oil to an emollient on barrier development in healthy term newborns. METHODS:In a prospective, random...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,随机对照试验
doi:10.1111/jocd.12302
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Acne vulgaris is one of the most common dermatological diseases, and it is known that various factors are related to triggering this condition in a patient. In particular, although the use of cosmetics is thought to be associated with the onset of a patient developing acne, there are few studies that have be...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13853
更新日期:2020-11-18 00:00:00
abstract:BACKGROUND:Human skin aging is caused by several factors, such as UV irradiation, stress, hormone, and pollution. Wrinkle formation and skin pigmentation are representative features of skin aging. Although EGF and arbutin are used as anti-wrinkle and skin whitening agents, respectively, they have adverse effects on ski...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12671
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Bimatoprost has known adnexal activity and was observed to increase nail growth at two clinical centers. OBJECTIVES:In this randomized, double-blinded, placebo-controlled pilot study, we examine the effect of bimatoprost (Lumigan 0.01%), applied bid to the proximal nail fold on nail growth, nail brittleness...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/jocd.12372
更新日期:2018-04-01 00:00:00
abstract::The American Academy of Dermatology (AAD) has prioritized skin cancer prevention efforts in 2018, as photoprotection measures adopted by the general public remain suboptimal. A large proportion of patients lack understanding of primary prevention methods for skin cancer, and mistruths in advertising may contribute sig...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12743
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Excess skin and fatty tissues beneath the jaw lead to a double chin deformity. Localized fat deposits in this area are a cause of discomfort and anguish, leading patients to undergo surgical procedures such as liposuction and dermolipectomy to improve the cosmetic effect. Both procedures require anesthesia a...
journal_title:Journal of cosmetic dermatology
pub_type: 临床试验,杂志文章
doi:10.1111/j.1473-2165.2007.00343.x
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:New treatments and techniques were being added over the last few years to treat atrophic scars with variable results and adverse effects. AIM OF THE WORK:The aim of this study was to evaluate and compare the therapeutic efficacy and safety of microneedling, autologous platelet-rich plasma, and combination o...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,随机对照试验
doi:10.1111/jocd.12356
更新日期:2017-09-01 00:00:00
abstract::The stratum corneum (SC) (i.e., the outermost layer of human skin) is a complex and paradoxical tissue composed of corneocytes and a matrix of intercellular lipids playing an essential role as the skin's protective barrier. The first paradox of SC is its dual nature. It is composed of nondividing (dead) cells embedded...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1473-2165.2008.00379.x
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Adult dermatological out patients have a 40% prevalence of psychiatric co-morbidity. If psychiatric co-morbidity is unrecognized, undetected and untreated, the consequences may be fatal. Acne is the most common skin disorder of the second and third decades of life. Acne and its treatments may cause depressio...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1473-2165.2002.00057.x
更新日期:2002-12-01 00:00:00
abstract::Cutaneous hypermelanoses are frequently encountered conditions that can have severe adverse psychosocial and emotional effects on affected patients. Melasma, postinflammatory hyperpigmentation, drug-induced pigmentation, and erythema dischromicum perstans are among the most common cutaneous disorders leading to acquir...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1473-2165.2006.00276.x
更新日期:2006-12-01 00:00:00
abstract:OBJECTIVE:To explore the influence of hyperbaric oxygen on scar formation in rabbit ears. METHODS:A total of 20 New Zealand rabbits were selected to establish the hypertrophic scar model on the ears. The rabbits were randomly divided into control group and experimental group (7d, 14d, 21d, and 28d group according to d...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12468
更新日期:2018-12-01 00:00:00
abstract::Recently, both doctors and patients pay particular attention to aesthetic medical services quality and efficacy of aesthetic adjustment implemented. It is essential to ensure research, analysis, and improving of botulinum toxin therapy quality and provide patients' orientation on the adjustment schedule, which include...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13584
更新日期:2021-02-01 00:00:00
abstract:INTRODUCTION:The ideal filler should be long-lasting, biocompatible, chemically inert, soft and easy to use, and have a long history of safety. This review focuses on the evolution and development of the PMMA-collagen gel, Bellafill, and the 10 years of postmarketing experience of Bellafill since it received premarket ...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
doi:10.1111/jocd.12539
更新日期:2018-06-01 00:00:00