Abstract：
BACKGROUND:Bimatoprost has known adnexal activity and was observed to increase nail growth at two clinical centers. OBJECTIVES:In this randomized, double-blinded, placebo-controlled pilot study, we examine the effect of bimatoprost (Lumigan 0.01%), applied bid to the proximal nail fold on nail growth, nail brittleness, and intraocular pressure. METHODS:Bimatoprost drops were placed on the proximal nail folds of 45 subjects on one hand (medication group) and vehicle drops to the other hand (control group). Baseline and final nail growth measurements, Goldmann applanation tensions of both eyes, and photos at 30 days were performed. Nail brittleness was subjectively graded. RESULTS:For the 38 subjects completing the study, the final mean nail growth of the hands, the net individual nail growth of the digits (excluding chipped nails), nail brittleness, and eye pressure readings were NS at P<.05. Photos revealed no increased hirsutism, but one subject with increased skin pigmentation. The drops were well tolerated without adverse effects. Nail chipping was a limitation of the study. CONCLUSIONS:Despite the negative results in this pilot study on nail growth and brittleness, further studies with higher bimatoprost concentration (0.03%) are warranted. We recommend monitoring nail growth by etching or marking the nail rather than measuring the full nail length due to our chipped nail findings.
journal_name
J Cosmet Dermatoljournal_title
Journal of cosmetic dermatologyauthors
Palmer DJ,Scheman A,Tanna AP,Bueno Adoi
10.1111/jocd.12372subject
Has Abstractpub_date
2018-04-01 00:00:00pages
263-267issue
2eissn
1473-2130issn
1473-2165journal_volume
17pub_type
杂志文章,多中心研究,随机对照试验abstract：BACKGROUND:Ultraviolet (UV) radiation exposure is related to skin and lip tumors. Therefore, the development of photoprotective lipstick formulations is of utmost importance. AIMS:Considering the biological properties of Shea butter (Butyrospermum parkii), we assessed its potential as an adjuvant in a molded lipstick ...
journal_title：Journal of cosmetic dermatology
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abstract：:In contrast to the female breast the male breast has gained much less attention by aesthetic surgery and cosmetic dermatology. In this review a focus on minimally invasive procedures to correct aesthetic problems of male breast are discussed. The major indications are gynecomastia, breast asymmetry, and body sculpturi...
journal_title：Journal of cosmetic dermatology
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abstract：:It is controversial whether or not humans convey specific compounds within their body odours which can potentially affect the physiology and behaviour of others. Such compounds are called pheromones and have been discovered in many other species, including mammals. It has been suggested that humans might have a specia...
journal_title：Journal of cosmetic dermatology
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abstract：BACKGROUND:Minimally invasive procedures provide effective, safe, relatively long-lasting, and natural results without large damage to the skin. A combination treatment is considered an approach that includes at least 2 different and unrelated modalities. OBJECTIVES:This study aims to evaluate the use and effectivenes...
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abstract：BACKGROUND:Injection techniques are growing, thanks to safer and more suitable filling agents. Hyaluronic acid (HA), a biodegradable product, has become the "gold standard" for fillers. With its wide range, it not only improves wrinkles but also restores volume. METHODS:Since 1996, many patients have been injected for...
journal_title：Journal of cosmetic dermatology
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abstract：BACKGROUND:Psoriasis is an inflammatory disease that is mostly immune-derived. It causes proliferation of skin cells, forming plaques. Psoriasis etiology is unknown. It might be multifactorial. AIMS:This work aimed to study Smad7 expression in psoriasis vulgaris patients in comparison with normal skin. PATIENTS/METHO...
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abstract：BACKGROUND:Topical cosmetic products can cause adverse reactions in some individuals, particularly those with sensitive skin who may develop irritations or allergic contact dermatitis. Evidence suggests that the frequency of self-reported sensitive skin is increasing in the general population, placing greater importanc...
journal_title：Journal of cosmetic dermatology
pub_type： 临床试验,杂志文章
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journal_title：Journal of cosmetic dermatology
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journal_title：Journal of cosmetic dermatology
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abstract：BACKGROUND:The harmful health effects of personal care products especially cosmetics have engulfed many societies of the world especially the female section without an alarm. OBJECTIVES:To estimate the prevalence of cosmetic usage and to assess the experiences of Saudi female undergraduate students in Wadi Al Dawasir ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
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journal_title：Journal of cosmetic dermatology
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abstract：BACKGROUND:Botulinum toxin is generally considered safe and has been used in constantly expanded cosmetic and therapeutic indications. However, long-term side effects such as granulomatous reactions have been associated with this drug. AIMS:We aim to evaluate a rare reaction to Botulonium toxin A injection. PATIENTS/...
journal_title：Journal of cosmetic dermatology
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abstract：BACKGROUND:Injectable fillers are widely used in aesthetic medicine. Polylactic acid (PLA) is a semipermanent filler that needs to be diluted with sterile water before injection. PLA has been associated with an increased risk of adverse reactions, specifically nodule formation. OBJECTIVE:To describe adverse reactions ...
journal_title：Journal of cosmetic dermatology
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doi：10.1111/j.1473-2165.2009.00417.x
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journal_title：Journal of cosmetic dermatology
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journal_title：Journal of cosmetic dermatology
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journal_title：Journal of cosmetic dermatology
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journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
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journal_title：Journal of cosmetic dermatology
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journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
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abstract：BACKGROUND:The application of ingredients from marine and maritime origins is increasingly common in skin care products, driven by consumer expectations for natural ingredients. However, these ingredients are typically studied for a few isolated in vitro activities. OBJECTIVES:The purpose of this study was to carry ou...
journal_title：Journal of cosmetic dermatology
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