Abstract:
:The carboxylic acids include alpha-hydroxyacids (AHAs), polyhydroxy acids (PHAs), aldobionic acids (ABAs), retinoic acid, vitamin C and azelaic acid. They all have therapeutic actions. AHAs, PHAs and ABAs are organic hydroxyacids, a group of natural and physiological substances which can modulate skin keratinization and increase biosynthesis of dermal components. Because of these effects, AHAs, PHAs and ABAs are therapeutically effective or beneficial for topical treatment of dry skin, rough skin, acne, rosacea, warts, eczema, psoriasis and skin changes associated with ageing, including wrinkles and photoageing. In addition, PHAs and ABAs, which are antioxidants, are topically beneficial for sensitive or diseased skin and for the prevention of oxidative damage caused by UV radiation. The vitamin A derivatives, known as retinoids, include three that are found physiologically. Retinoic acid is the most potent of these in promoting proliferation and differentiation of epithelial cells, and in stimulating biosynthesis of collagen I and III. Because of these actions, retinoic acid is therapeutically effective for topical treatment of acne, actinic keratoses and photoaged skin. Vitamin C, which is l-ascorbic acid and a lactone form of 3-keto-polyhydroxy acid, is a water-soluble antioxidant. Because of this property vitamin C has been promoted for topical prevention of skin damage caused by UV radiation. Azelaic acid has been shown to normalize keratinization in the follicular infundibulum, exert an antibacterial effect against Propionibacterium acnes and inhibit melanogenesis and so has been used for topical treatment of acne and melasma. The carboxylic acids display similarities and differences in their topical actions and therapeutic applications.
journal_name
J Cosmet Dermatoljournal_title
Journal of cosmetic dermatologyauthors
Yu RJ,Van Scott EJdoi
10.1111/j.1473-2130.2004.00059.xsubject
Has Abstractpub_date
2004-04-01 00:00:00pages
76-87issue
2eissn
1473-2130issn
1473-2165pii
JCD059journal_volume
3pub_type
杂志文章abstract:BACKGROUND:Age-associated volume loss is now known to play an important role in the structural changes of the aging face. In the lower face, this manifests as drooping of the corners of the mouth and jowl leading to a loss of the oval jawline of youth. Jawline reshaping by replacing volume has therefore become an indis...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12074
更新日期:2014-03-01 00:00:00
abstract:INTRODUCTION:The addition of hydrophobically modified polymers (HMPs) to cleansers that contain surfactants can create polymer-surfactant complexes that are less irritating to the skin than commercially available mild cleansers. Our objective was to compare the tolerability and efficacy of a test foaming liquid facial ...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,随机对照试验
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更新日期:2013-12-01 00:00:00
abstract::The use of fillers in esthetic rejuvenation or reshaping has been well established and is one of toughest techniques for beginners due to segmental attachments and proximity to important anatomical structures in the infraorbital area making it difficult to achieve smooth esthetic results. To make filling easy, smooth,...
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abstract:BACKGROUND:Androgenetic alopecia is a common cosmetic hair disorder, resulting from interplay of genetic, endocrine, and aging factors leading to a patterned follicular miniaturization. Microinflammation seems to be a potential active player in this process. AIMS:To study the histopathological and ultrastructural chan...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Scalp psoriasis is reported to occur in 50-80% of psoriasis sufferers. Treatment of scalp psoriasis requires special consideration of product esthetics and staining potential due to the presence of hair. AIM:To evaluate the potential of a new, marketed liquor carbonis distillate (LCD; coal tar) solution to ...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:Undecylenoyl phenylalanine is a novel skin-lightening agent, probably acting as α-melanocyte-stimulating hormone (α-MSH) and beta-adrenergic receptor (β-ADR) antagonist. OBJECTIVES:The objective of this double-blind randomized comparative study was to evaluate the efficacy and safety of a preparation contai...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,随机对照试验
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更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:As the face is known for its extreme variation in vascular anatomy and the number of filler-associated complications due to intra-arterial injection is increasing, we are in need of a method to visualize anyone's individual arterial anatomy of the face in a completely harmless way. AIMS:The different medica...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
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更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:Since air pollution is only one of many environmental stressors that can affect skin, it has been challenging to identify skin appearance or functional features profoundly affected by chronic exposure to traffic-derived air pollution. AIMS:The current population study focused on taxi drivers working in urba...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Energy-based devices are increasingly used for noninvasive body contouring. Our aim was to investigate the clinical efficacy of combined radiofrequency and ultrasound device for reduction in body circumference in various body parts. AIMS:The aim of our study was to investigate the clinical efficacy of combi...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2020-12-19 00:00:00
abstract:BACKGROUND:To investigate the effectiveness of the posterior temporal supraSMAS minimally invasive lifting technique and compared it to experiments performed in fresh human body donors by applying skin vector displacement measurement technology. MATERIALS AND METHODS:A total of 15 patients (14 females/1 male) with a m...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12722
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Adult dermatological out patients have a 40% prevalence of psychiatric co-morbidity. If psychiatric co-morbidity is unrecognized, undetected and untreated, the consequences may be fatal. Acne is the most common skin disorder of the second and third decades of life. Acne and its treatments may cause depressio...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1473-2165.2002.00057.x
更新日期:2002-12-01 00:00:00
abstract:OBJECTIVE:To provide retrospective clinical review of some uncommonly reported side effects of long-pulsed alexandrite laser treatment for hair removal. MATERIAL AND METHODS:Two hundred and fifty female patients suffering from hirsutism of the face were subjected to treatment by long pulse alexandrite laser for a maxi...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/j.1473-2165.2009.00465.x
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVE:Currently, the cosmetic and medical industries are paying considerable attention to solve or prevent skin damage or diseases, such as hyperpigmentation and oxidation and free radical damage. In this study, the effective compounds in Myrica rubra fruit were extracted and studied the biological effects of these...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Platelet-rich plasma is highly enriched plasma that contains a large concentration of platelets that secrete various growth factors and is used in a wide variety of surgical and cosmetic procedures, including hair regrowth and skin rejuvenation. METHODS:Microneedling therapy is being combined with platelet-...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12772
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:The sebaceous gland and the follicular bulge region have important role in biology of the hair. They initiate destruction of the hair follicle both in human and animal models in certain conditions. The morphometric feature of the sebaceous gland is not well understood so as the distribution of the bulge stem...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12153
更新日期:2015-09-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13773
更新日期:2020-10-08 00:00:00
abstract::Facial expressions convey emotions that form the foundation of interpersonal relationships, and many of these emotions promote and regulate our social linkages. Hence, the facial aging symptomatological analysis and the treatment plan must of necessity include knowledge of the facial dynamics and the emotional express...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12128
更新日期:2015-03-01 00:00:00
abstract::Many cosmetic companies utilize in vitro gene array studies to display significant stimulation or inhibition of various human skin biomarkers to validate in vivo actions that are reported to enhance dermal health. This follows the central dogma of DNA-to-RNA results in protein expression; however, gene and protein exp...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12362
更新日期:2018-04-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2019-12-01 00:00:00
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journal_title:Journal of cosmetic dermatology
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更新日期:2019-02-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
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更新日期:2006-03-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12081
更新日期:2014-06-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2021-02-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
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更新日期:2006-12-01 00:00:00
abstract:BACKGROUND:Childhood vitiligo is commonly encountered. Pattern and distribution of childhood vitiligo were not clearly described in past. AIMS:To study clinical characteristics of vitiligo among Egyptian children in relation to epidemiological data and compare them with those of adolescents and adults. PATIENTS AND M...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Type XVI collagen is a member of the fibril-associated collagens with interrupted triple helices; however, its function or regulation remain unclear. AIMS:This study is to examine the effect of ultraviolet B (UVB) or photoaging on type XVI collagen expression in various cultured cells, mouse, and human skin...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/j.1473-2165.2012.00612.x
更新日期:2012-09-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2017-09-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2020-10-14 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,随机对照试验
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更新日期:2018-10-01 00:00:00
abstract::Today, most do not go a day without practicing or hearing about new hair removal methods. However, little is discussed about the history of hair removal and the development of most hair removal methods since the period of cavemen. Avoiding decapitation and fitting in with society are two of many reasons for the develo...
journal_title:Journal of cosmetic dermatology
pub_type: 历史文章,杂志文章
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更新日期:2013-06-01 00:00:00