The frequency of polycystic ovary syndrome in females with resistant acne vulgaris.

Abstract:

BACKGROUND:Acne vulgaris in females may be resistant to treatment in spite of topical and systemic therapy for a sufficient period. In this condition, acne may be a manifestation of underlying endocrine conditions such as polycystic ovary syndrome (PCOS). OBJECTIVE:To evaluate the frequency of PCOS in females with resistant acne vulgaris. Patients and methods This case-controlled study was conducted in the Department of Dermatology and Venereology in The Teaching Hospital in Al-Najaf during the period from October 2007 to November 2008. One hundred and twenty-three female patients with resistant acne vulgaris were included in this study. One hundred and twenty-three women, age-matched, without acne were enrolled as a control group. Detailed history, clinical examination, abdominal ultrasound study, and hormonal assays were obtained for the patients and the control group. RESULTS:One hundred and twenty-three females with resistant acne were included; their ages ranged from 17 to 40 years with a mean of 25.016 +/- 6.041 (SD). One hundred and twenty-three control women without acne were enrolled; their ages ranged from 17-40 years with a mean of 26.014 +/- 6.251 (SD). The patients and the control group are age-matched (P = 0.192). It was found that 63 patients (51.2%) with resistant acne have PCOS in comparison to only eight control women (6.2%). The difference is highly significant. CONCLUSION:Polycystic ovary syndrome is an important contributing factor in females with resistant acne vulgaris.

journal_name

J Cosmet Dermatol

authors

Maluki AH

doi

10.1111/j.1473-2165.2010.00500.x

subject

Has Abstract

pub_date

2010-06-01 00:00:00

pages

142-8

issue

2

eissn

1473-2130

issn

1473-2165

pii

JCD500

journal_volume

9

pub_type

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