Novel cutaneous uses for botulinum toxin type A.

Abstract:

:Botulinum toxin type A is a neurotoxin produced by the bacterium Clostridium botulinum which causes a flaccid muscle paralysis. It has been used extensively in the field of dermatology for the treatment of dynamic rhytides and in the treatment of hyperhidrosis. Botulinum toxin has an excellent safety profile and few side effects when used for these purposes. Recently, botulinum toxin has also been used experimentally in a number of other dermatologic conditions with good results. These conditions include: persistent facial flushing, gustatory sweating and epiphora, anal fissures, familial benign pemphigus (Hailey-Hailey disease), dyshidrotic eczema, and following surgical wound closures. While randomized, controlled prospective trials are still needed to further understand the efficacy and safety of botulinum toxin in these conditions, anecdotal and case report data suggest that botulinum toxin is both safe and efficacious in these and many other procedures.

journal_name

J Cosmet Dermatol

authors

Bansal C,Omlin KJ,Hayes CM,Rohrer TE

doi

10.1111/j.1473-2165.2006.00255.x

subject

Has Abstract

pub_date

2006-09-01 00:00:00

pages

268-72

issue

3

eissn

1473-2130

issn

1473-2165

pii

JCD255

journal_volume

5

pub_type

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