Medium-depth and deep chemical peels.


:Chemical peeling, also known as chemoexfoliation or dermapeeling, is performed to improve the skin's appearance as it reduces the wrinkles caused by aging and the features of photoaged skin. Although the best results are obtained with deep peels, the medium-depth peels allow to obtain excellent results without the dangerous side effects of deep peels. Medium-depth peelings are performed with trichloroacetic acid (TCA) at 35-50% alone or at 35% in combination with Jessner's solution, 70% glycolic acid, and solid CO(2). TCA must be applied with a cotton-tipped applicator or saturated gauze pads with smooth strokes. After application, a dry gauze pad must be used to blot the excess TCA from the skin. Postoperative care of 35% TCA peeling consists of cleansing during the following days. Habitually, medium-depth peelings with TCA alone or in combination have no complications. Sometimes, as a consequence of the patient's type of skin, the practitioner's lack of experience or other circumstances, complications such as hyper- or hypopigmentation, erythema, hypertrophiyc and keloid scars, infections, and milia may occur. Deep peeling with phenol has two modalities: unoccluded and occluded Baker's formula phenol. Unoccluded phenol peels is similar to the medium-depth peeling with Jessner's solution + TCA at 35%, but it has the disadvantage that it may produce cardiac and renal complications. This kind of peeling must be applied more slowly, and it is specific for the eyelids in full-face deep peeling. Afterpeel care is the same as that of medium-depth peeling. Complications of deep peelings can be cardiac arrhythmias, hypertrophic scars, infections, prolonged erythema, pigmentary changes, cutaneous atrophy, and exceptionally toxic shock syndrome.


J Cosmet Dermatol


Camacho FM




Has Abstract


2005-06-01 00:00:00














  • Successful treatment of plantar warts using topical Zijinding, a traditional Chinese medicine preparation: A case series.

    abstract:INTRODUCTION:Plantar warts are associated with high transmissibility and morbidity. Among the available therapeutic options, none is uniformly effective or virucidal. Salicylic acid is the first-line therapy but approximately one-third of lesions could not resolve and become recalcitrant despite repeated treatment. Cry...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Zhao Y,Sridhar S,Guo L,Lau SKP,Xu Y,Woo PCY

    更新日期:2020-04-01 00:00:00

  • Subcision™ plus poly-l-lactic acid for the treatment of cellulite associated to flaccidity in the buttocks and thighs.

    abstract:BACKGROUND:There is a growing demand for procedures to treat cellulite. Subcision™ is widely used for cellulite correction, and injectable poly-L-lactic acid (PLLA) has been shown to be an effective option for various body conditions. AIMS:Present the results of combining Subcision™ plus PLLA, in the same session, in ...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Mazzuco R

    更新日期:2020-05-01 00:00:00

  • A double-blind vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of melasma in females.

    abstract:BACKGROUND:Undecylenoyl phenylalanine is a novel skin-lightening agent, probably acting as α-melanocyte-stimulating hormone (α-MSH) and beta-adrenergic receptor (β-ADR) antagonist. OBJECTIVES:The objective of this double-blind randomized comparative study was to evaluate the efficacy and safety of a preparation contai...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章,随机对照试验


    authors: Katoulis A,Alevizou A,Soura E,Mantas N,Bozi E,Gregoriou S,Makris M,Rigopoulos D

    更新日期:2014-06-01 00:00:00

  • A review of protection against exposome factors impacting facial skin barrier function with 89% mineralizing thermal water.

    abstract:BACKGROUND:The skin exposome refers to the constellation of external exposures that contribute to cutaneous aging, including solar radiation, air pollution, tobacco smoke, unbalanced nutrition, and cosmetic products. This review explores the skin exposome and the role of a combination hyaluronic acid and mineralized th...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章,评审


    authors: Salsberg J,Andriessen A,Abdulla S,Ahluwalia R,Beecker J,Sander M,Schachter J

    更新日期:2019-06-01 00:00:00

  • Rosacea in acne vulgaris patients: Subtype distribution and triggers assessment-A cross-sectional study.

    abstract:BACKGROUND:Recent studies have reported that the incidence of acne combined with rosacea is increasing. However, the clinical feature and inducing factor of these two diseases co-occurrence is remain unclear. AIMS:This study aims to investigate the classification and severity of female patients combining with acne and...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Chen H,Lai W,Zheng Y

    更新日期:2020-10-06 00:00:00

  • Development and cathodic iontophoretic permeation evaluation of liquid crystalline systems provided of retinoic acid microparticles.

    abstract:BACKGROUND:The intracellular form of action of retinoids requires these agents to reach deeper layers of the skin with viable cells to ensure therapeutic efficiency. However, studies on swine skin models show that some retinoids have low skin permeability. Thus, the association of innovative formulations with technolog...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Monteiro E Silva SA,Ricci Leonardi G

    更新日期:2020-11-03 00:00:00

  • Role of KLF2: New insight in inflammatory acne pathogenesis.

    abstract:BACKGROUND:Acne is an inflammatory skin condition of pilosebaceous unit. Its pathogenesis is multifactorial with a central role of inflammatory and pro-inflammatory cytokines mediators. Downregulated Kruppel-like factor 2 (KLF2) leads to rapid secretion of many cytokines that are involved in acne pathogenesis. AIMS:Th...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Ibrahim MA,Mohammed SA,Elhabak DM

    更新日期:2020-07-05 00:00:00

  • The efficacy and safety of permethrin 2.5% with tea tree oil gel on rosacea treatment: A double-blind, controlled clinical trial.

    abstract:BACKGROUND:Rosacea is a chronic skin condition that typically affects the face and it results in redness and inflammation. The main risk factors of this disease are Demodex folliculorum, living in the pilosebaceous units. AIMS:To evaluate the efficacy and safty of permethrin 2.5% in combination with tea tree oil (TTO)...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Ebneyamin E,Mansouri P,Rajabi M,Qomi M,Asgharian R,Azizian Z

    更新日期:2020-06-01 00:00:00

  • Cross talk between oxidative stress and inflammation in alopecia areata.

    abstract:BACKGROUND:Although the etiopathogenesis of alopecia areata (AA) is still unclear, inflammation, oxidative stress, and subsequent DNA damage might be considered role players in disease development. AIM:We aimed at exploring the potential link between oxidative DNA damage and inflammation in AA patients through measuri...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Mustafa AI,Khashaba RA,Fawzy E,Baghdady SMA,Rezk SM

    更新日期:2020-10-25 00:00:00

  • Treatment of Nevus lipomatosus cutaneous superficialis with CO2 laser.

    abstract::Nevus lipomatosus cutaneous superficialis (NLCS) is an uncommon lesion characterized by ectopic adipose tissue in the dermis and can be generalized or localized. It presents as a soft skin colored to yellowish papules or cerebriform plaques occurring usually on the buttock or thigh in a segment distribution. We report...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Sardana K,Bansal S,Garg VK,Khurana N

    更新日期:2017-09-01 00:00:00

  • The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials.

    abstract:BACKGROUND:Skin dryness and an accelerated fragmentation of the collagen network in the dermis are hallmarks of skin aging. Nutrition is a key factor influencing skin health and consequently its appearance. A wide range of dietary supplements is offered to improve skin health. Collagen peptides are used as a bioactive ...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章,随机对照试验


    authors: Asserin J,Lati E,Shioya T,Prawitt J

    更新日期:2015-12-01 00:00:00

  • Smad7 in psoriasis vulgaris patients: A clinical and immunohistochemical study.

    abstract:BACKGROUND:Psoriasis is an inflammatory disease that is mostly immune-derived. It causes proliferation of skin cells, forming plaques. Psoriasis etiology is unknown. It might be multifactorial. AIMS:This work aimed to study Smad7 expression in psoriasis vulgaris patients in comparison with normal skin. PATIENTS/METHO...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Hemida AS,Hammam MA,Salman ATA,Shehata WA

    更新日期:2020-12-01 00:00:00

  • New soft tissue filler derived from autologous keratin and fibroblast for neck wrinkles.

    abstract:OBJECTIVE:To assess the effectiveness of injection of autologous keratin gel and fibroblast for neck aging as soft tissue filler. MATERIALS AND METHODS:Totally 30 volunteers received treatment of autologous keratin and fibroblast for neck wrinkles and 5 of them received hyaluronic acid (HA) treatment as control. Clini...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章,随机对照试验


    authors: Wang Y,Wang B,Zhang Q,Ma J

    更新日期:2018-08-01 00:00:00

  • A new phytocosmetic preparation from Thymus vulgaris stimulates adipogenesis and controls skin aging process: In vitro studies and topical effects in a double-blind placebo-controlled clinical trial.

    abstract:BACKGROUND:The use of the injectable products for soft tissue augmentation and treatment of skin aging is an uncomfortable, invasive and related to several complications, and chronic reactions, mainly after long-term application. Efforts to develop new topically active anti-aging products with fewer adverse effects are...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Caverzan J,Mussi L,Sufi B,Padovani G,Nazato L,Camargo FB Junior,Magalhães WV,Di Stasi LC

    更新日期:2020-11-10 00:00:00

  • Tattoo: Ancient art and current problems.

    abstract::The popularity of tattoos in the today's society brings with it a significant increase of the incidence of associated cutaneous reactions. Among the several complications that may occur after a tattooing procedure, allergic and photo-allergic reactions, infections, and Koebner phenomenon are the most common ones obser...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Gualdi G,Fabiano A,Moro R,Venturuzzo A,Monari P,Calzavara-Pinton P,Amerio P

    更新日期:2021-02-01 00:00:00

  • Efficacy and safety of a new hyaluronic acid filler for nasolabial folds: A 52-week, multicenter, randomized, evaluator/subject-blind, split-face study.

    abstract:BACKGROUND:Hyaluronic acid fillers are known to be effective for correction of nasolabial folds. Recently, a novel biphasic hyaluronic acid filler incorporating lidocaine, DIVAVIVA medium has been introduced. OBJECTIVES:We compared the efficacy and safety between DIVAVIVA medium and Restylane Perlane Lidocaine for mod...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Cheon HI,Kim JH,Kim BJ,Lee YW

    更新日期:2020-10-08 00:00:00

  • Clinical efficacy of 0.5% topical mangosteen extract in nanoparticle loaded gel in treatment of mild-to-moderate acne vulgaris: A 12-week, split-face, double-blinded, randomized, controlled trial.

    abstract:BACKGROUND:Acne vulgaris is the most common inflammatory sebaceous gland disorder in young adults. The resistant strains of Propionibacterium acnes (P. acnes) are of increasing concern in the treatment of acne. OBJECTIVES:To evaluate the efficacy of 0.5% topical mangosteen extract in nanoparticle loaded gel (containin...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Lueangarun S,Sriviriyakul K,Tempark T,Managit C,Sithisarn P

    更新日期:2019-01-27 00:00:00

  • Age-dependent changes in damage processes of hair cuticle.

    abstract:BACKGROUND:Human hair cuticle is always exposed to various stresses and then gradually lost in daily life. There are two typical patterns of cuticle damage: type L, where the cell membrane complex, the structure located between cuticle cells, is split and the cuticle lifts up, and type E, where the fragile substructure...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Takahashi T,Mamada A,Breakspear S,Itou T,Tanji N

    更新日期:2015-03-01 00:00:00

  • Medicinal and cosmetics soap production from Jatropha oil.

    abstract::Soap is the most useful things which we use our everyday life in various cleansing and cosmetics purposes. Jatropha oil is nonedible oil which has more benefits to soap making. It has also cosmetics and medicinal properties. But the presence of toxic Phorbol esters in Jatropha oil is the main constrains to use it. So ...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章,评审


    authors: Shahinuzzaman M,Yaakob Z,Moniruzzaman M

    更新日期:2016-06-01 00:00:00

  • Modified phenol peels for treatment-refractory hyperpigmentation of lichen planus pigmentosus: A retrospective clinico-dermoscopic analysis.

    abstract:BACKGROUND:Lichen Planus Pigmentosus (LPP), a disorder with stubborn treatment-refractory hyperpigmentation predominantly affects the darker skin. Deep dermal pigmentary incontinence of LPP renders the condition treatment-refractory. OBJECTIVES:Lack of a consistently effective depigmenting treatment protocol of inacti...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Sonthalia S,Vedamurthy M,Thomas M,Goldust M,Jha AK,Srivastava S,Aggarwal I

    更新日期:2019-01-20 00:00:00

  • Real-world assessment, relevance, and problems in use of personal protective equipment in clinical dermatology practice in a COVID referral tertiary hospital.

    abstract:BACKGROUND:Doctors and healthcare workers (HCW) are at frontline in control of the pandemic caused by the novel coronavirus infection (COVID-19). The virus is transmitted by contact, droplet, and airborne transmission; hence, hand hygiene, social distancing, environmental disinfection, and use of appropriate personal p...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章,评审


    authors: Arora P,Sardana K,Sinha S

    更新日期:2020-12-01 00:00:00

  • Hydroquinone and its analogues in dermatology - a potential health risk.

    abstract::Hydroquinone has been used for decades as a skin lightening agent. Since January 1, 2001, its use in cosmetics has been banned. This ban is as a result of mid-term effects such as leukoderma-en-confetti/occupational vitiligo and exogenous ochronosis. However, a recent literature search on hydroquinone as a skin lighte...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Westerhof W,Kooyers TJ

    更新日期:2005-06-01 00:00:00

  • Anti-aging and filling efficacy of six types hyaluronic acid based dermo-cosmetic treatment: double blind, randomized clinical trial of efficacy and safety.

    abstract:BACKGROUND:Human skin aging is a multifactorial and complex biological process affecting the different skin constituents. Even if the skin aging mechanism is not yet fully unravelled is evident that epidermis loses the principal molecule responsible for binding and retaining water molecules, resulting in loss of skin m...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章,随机对照试验


    authors: Nobile V,Buonocore D,Michelotti A,Marzatico F

    更新日期:2014-12-01 00:00:00

  • Comparison of two methods of subcision Nokor and blunt blade in acne scars treatment.

    abstract:CONTEXT:Subcision is a simple surgical method that can be effective in treatment of acne scars. AIMS:This study was conducted to evaluate and compare the two methods of Nokor needle and blunt blade (BB) subcision in treatment of acne scars. SETTINGS AND DESIGN:This clinical trial study was conducted on 28 patients wi...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Asilian A,Faghihi G,Asemi Esfahani A,Mokhtari F,Nilforoushzadeh M,Mozafarpoor S

    更新日期:2019-12-01 00:00:00

  • An observational study of a 24 mg/mL hyaluronic acid with pre-incorporated lidocaine for lip definition and enhancement.

    abstract:BACKGROUND:Lip enhancement using fillers improves appearance by increasing fullness, enhancing lip definition, and reducing fine lines and wrinkles around the lips. AIMS:To investigate a 24 mg/mL hyaluronic acid (HA) with pre-incorporated lidocaine gel for lip definition and enhancement, medium-deep lines, and oral co...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Lanigan S

    更新日期:2011-03-01 00:00:00

  • Melasma: How hormones can modulate skin pigmentation.

    abstract::We described-along with a genetic predisposition and exposure to sunlight, as the main factors for melasma development-pregnancy, hormonal therapies, and oral contraceptive pills. Whilst hormonal alteration or therapies are frequently reported in literature in association with melasma, studies analyzing the laboratori...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章,评审


    authors: Filoni A,Mariano M,Cameli N

    更新日期:2019-04-01 00:00:00

  • Traffic-derived air pollution compromises skin barrier function and stratum corneum redox status: A population study.

    abstract:BACKGROUND:Since air pollution is only one of many environmental stressors that can affect skin, it has been challenging to identify skin appearance or functional features profoundly affected by chronic exposure to traffic-derived air pollution. AIMS:The current population study focused on taxi drivers working in urba...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Huang N,Mi T,Xu S,Dadd T,Ye X,Chen G,Du Y,Santhanam U

    更新日期:2020-07-01 00:00:00

  • Human skin gene expression doesn't correlate with protein expression? Unless both parameters are quantified.

    abstract::Many cosmetic companies utilize in vitro gene array studies to display significant stimulation or inhibition of various human skin biomarkers to validate in vivo actions that are reported to enhance dermal health. This follows the central dogma of DNA-to-RNA results in protein expression; however, gene and protein exp...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Lephart ED

    更新日期:2018-04-01 00:00:00

  • Measurements of tension on wound edges after strip harvest surgery.

    abstract:OBJECTIVE:To measure the wound closure tension after strip surgery. MATERIALS AND METHODS:The study was conducted in a private setup on patients undergoing first hair restoration surgery. The donor strip was marked with the patient in sitting position after checking the vertical scalp mobility. Six stitches of nonabso...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Ahmad M

    更新日期:2019-06-01 00:00:00

  • A novel protein-based autologous topical serum for skin regeneration.

    abstract:BACKGROUND:As skin ages, a functional decrement occurs. To avoid future vulnerability to dermatologic diseases, an optimal cutaneous regeneration is mandatory. Biological therapies based on blood-derived autologous proteins are gaining attention of scientists and dermatologists. OBJECTIVES:A novel 100% autologous topi...

    journal_title:Journal of cosmetic dermatology

    pub_type: 杂志文章


    authors: Anitua E,Troya M,Pino A

    更新日期:2020-03-01 00:00:00