Falling tuition revenues could pinch US universities.

abstract：:The interaction of lectins with carbohydrate receptors on the plasma membrane of eukaryotic cells results in a wide variety of biological effects. One effect which has been extensively studied is the stimulation of lymphocytes to blastogenesis and proliferation. High doses of concanavalin A (Con A) and phytohaemagglut...

journal_title：Nature

authors： Hilgert I,Horejsí V,Angelisová P,Kristofová H

更新日期：1980-03-20 00:00:00

abstract：:In the Caenorhabditis elegans hermaphrodite germ line, sperm and then oocytes are made from a common pool of germ-cell precursors. The decision to differentiate as a sperm or an oocyte is regulated by the sex-determining gene, fem-3. Expression of fem-3 in the hermaphrodite germ line directs spermatogenesis and must b...

journal_title：Nature

authors： Ahringer J,Kimble J

更新日期：1991-01-24 00:00:00

abstract：:Molecular-scale manipulation of electronic and ionic charge accumulation in materials is the backbone of electrochemical energy storage1-4. Layered van der Waals (vdW) crystals are a diverse family of materials into which mobile ions can electrochemically intercalate into the interlamellar gaps of the host atomic latt...

journal_title：Nature

authors： Bediako DK,Rezaee M,Yoo H,Larson DT,Zhao SYF,Taniguchi T,Watanabe K,Brower-Thomas TL,Kaxiras E,Kim P

更新日期：2018-06-01 00:00:00

abstract：: ...

journal_title：Nature

authors：

更新日期：2018-11-01 00:00:00

abstract：:Expression of Ets2, a proto-oncogene and transcription factor, occurs in a variety of cell types. During murine development it is highly expressed in newly forming cartilage, including in the skull precursor cells and vertebral primordia. Ets2 is located on human chromosome 21 (ref. 8) and is overexpressed in Down's s...

journal_title：Nature

authors： Sumarsono SH,Wilson TJ,Tymms MJ,Venter DJ,Corrick CM,Kola R,Lahoud MH,Papas TS,Seth A,Kola I

更新日期：1996-02-08 00:00:00

abstract：:The classical strength profile of continents is derived from a quasi-static view of their rheological response to stress--one that does not consider dynamic interactions between brittle and ductile layers. Such interactions result in complexities of failure in the brittle-ductile transition and the need to couple ener...

journal_title：Nature

authors： Regenauer-Lieb K,Weinberg RF,Rosenbaum G

更新日期：2006-07-06 00:00:00

abstract：:In mammals, one of the most pronounced consequences of viral infection is the induction of type I interferons, cytokines with potent antiviral activity. Schlafen (Slfn) genes are a subset of interferon-stimulated early response genes (ISGs) that are also induced directly by pathogens via the interferon regulatory fact...

journal_title：Nature

authors： Li M,Kao E,Gao X,Sandig H,Limmer K,Pavon-Eternod M,Jones TE,Landry S,Pan T,Weitzman MD,David M

更新日期：2012-11-01 00:00:00

abstract：:To trigger class II-restricted T cells, antigen presenting cells have to capture antigens, process them and display their fragments in association with class II molecules. In most species, activated T cells express class II molecules; however, no evidence has been found that these cells can present soluble antigens. T...

journal_title：Nature

authors： Lanzavecchia A,Roosnek E,Gregory T,Berman P,Abrignani S

更新日期：1988-08-11 00:00:00

abstract：:Observations show that the seismic normal modes of the Earth at frequencies near 10 mHz are excited at a nearly constant level in the absence of large earthquakes. This background level of excitation has been called the 'hum' of the Earth, and is equivalent to the maximum excitation from a magnitude 5.75 earthquake. I...

journal_title：Nature

authors： Webb SC

更新日期：2007-02-15 00:00:00

abstract：:Many physiological events require transient increases in cytosolic Ca(2+) concentrations. Ryanodine receptors (RyRs) are ion channels that govern the release of Ca(2+) from the endoplasmic and sarcoplasmic reticulum. Mutations in RyRs can lead to severe genetic conditions that affect both cardiac and skeletal muscle, ...

journal_title：Nature

authors： Tung CC,Lobo PA,Kimlicka L,Van Petegem F

更新日期：2010-11-25 00:00:00

abstract：:Graphene oxide membranes-partially oxidized, stacked sheets of graphene-can provide ultrathin, high-flux and energy-efficient membranes for precise ionic and molecular sieving in aqueous solution. These materials have shown potential in a variety of applications, including water desalination and purification, gas and ...

journal_title：Nature

authors： Chen L,Shi G,Shen J,Peng B,Zhang B,Wang Y,Bian F,Wang J,Li D,Qian Z,Xu G,Liu G,Zeng J,Zhang L,Yang Y,Zhou G,Wu M,Jin W,Li J,Fang H

更新日期：2017-10-19 00:00:00

abstract：:The brain cholecystokinin-B/gastrin receptor (CCK-B/gastrin) has been implicated in mediating anxiety, panic attacks, satiety, and the perception of pain. The canine and human CCK-B/gastrin receptors share 90% amino-acid identity and have similar agonist affinities. These receptors can be selectively blocked by the no...

journal_title：Nature

authors： Beinborn M,Lee YM,McBride EW,Quinn SM,Kopin AS

更新日期：1993-03-25 00:00:00

abstract：:Gravitational lensing is a powerful tool for the study of the distribution of dark matter in the Universe. The cold-dark-matter model of the formation of large-scale structures (that is, clusters of galaxies and even larger assemblies) predicts the existence of quasars gravitationally lensed by concentrations of dark ...

journal_title：Nature

authors： Inada N,Oguri M,Pindor B,Hennawi JF,Chiu K,Zheng W,Ichikawa S,Gregg MD,Becker RH,Suto Y,Strauss MA,Turner EL,Keeton CR,Annis J,Castander FJ,Eisenstein DJ,Frieman JA,Fukugita M,Gunn JE,Johnston DE,Kent SM,Nichol

更新日期：2003-12-18 00:00:00

abstract：:Nuclear exclusion of the PTEN (phosphatase and tensin homologue deleted in chromosome 10) tumour suppressor has been associated with cancer progression. However, the mechanisms leading to this aberrant PTEN localization in human cancers are currently unknown. We have previously reported that ubiquitinylation of PTEN a...

journal_title：Nature

authors： Song MS,Salmena L,Carracedo A,Egia A,Lo-Coco F,Teruya-Feldstein J,Pandolfi PP

更新日期：2008-10-09 00:00:00

abstract：:The TGF-beta/activin/BMP cytokine family signals through serine/threonine kinase receptors, but how the receptors transduce the signal is unknown. The Mad (Mothers against decapentaplegic) gene from Drosophila and the related Sma genes from Caenorhabditis elegans have been genetically implicated in signalling by membe...

journal_title：Nature

authors： Liu F,Hata A,Baker JC,Doody J,Cárcamo J,Harland RM,Massagué J

更新日期：1996-06-13 00:00:00

abstract：:Since 2013 the occurrence of human infections by a novel avian H7N9 influenza virus in China has demonstrated the continuing threat posed by zoonotic pathogens. Although the first outbreak wave that was centred on eastern China was seemingly averted, human infections recurred in October 2013 (refs 3-7). It is unclear ...

journal_title：Nature

authors： Lam TT,Zhou B,Wang J,Chai Y,Shen Y,Chen X,Ma C,Hong W,Chen Y,Zhang Y,Duan L,Chen P,Jiang J,Zhang Y,Li L,Poon LL,Webby RJ,Smith DK,Leung GM,Peiris JS,Holmes EC,Guan Y,Zhu H

更新日期：2015-06-04 00:00:00

abstract：:Temperature-sensitive paralysis is the most striking defect of adult Drosophila carrying the shibire mutation. This is believed to be due to a reversible block of endocytosis, which prevents membrane cycling and thus depletes synaptic vesicles. The shibire mutation also affects many tissues outside the nervous system....

journal_title：Nature

authors： van der Bliek AM,Meyerowitz EM

更新日期：1991-05-30 00:00:00

abstract：:How to image objects that are hidden from a camera's view is a problem of fundamental importance to many fields of research, with applications in robotic vision, defence, remote sensing, medical imaging and autonomous vehicles. Non-line-of-sight (NLOS) imaging at macroscopic scales has been demonstrated by scanning a ...

journal_title：Nature

authors： O'Toole M,Lindell DB,Wetzstein G

更新日期：2018-03-15 00:00:00

abstract：:Estimates of the total number of bacterial species indicate that existing DNA sequence databases carry only a tiny fraction of the total amount of DNA sequence space represented by this division of life. Indeed, environmental DNA samples have been shown to encode many previously unknown classes of proteins and RNAs. B...

journal_title：Nature

authors： Weinberg Z,Perreault J,Meyer MM,Breaker RR

更新日期：2009-12-03 00:00:00

abstract：:Tumour cells become addicted to the expression of initiating oncogenes like Ras, such that loss of oncogene expression in established tumours leads to tumour regression. HRas, NRas or KRas are mutated to remain in the active GTP-bound oncogenic state in many cancers. Although Ras activates several proteins to initiate...

journal_title：Nature

authors： Lim KH,Ancrile BB,Kashatus DF,Counter CM

更新日期：2008-04-03 00:00:00

abstract：:Understanding the fluctuations in marine fish stocks is important for the management of fisheries, and attempts have been made to demonstrate links with oceanographic and climatic variability, including the North Atlantic Oscillation (NAO). The NAO has been correlated with a range of long-term ecological measures, inc...

journal_title：Nature

authors： Attrill MJ,Power M

更新日期：2002-05-16 00:00:00

abstract：:Ribosomes are translational machineries that catalyse protein synthesis. Ribosome structures from various species are known at the atomic level, but obtaining the structure of the human ribosome has remained a challenge; efforts to address this would be highly relevant with regard to human diseases. Here we report the...

journal_title：Nature

authors： Khatter H,Myasnikov AG,Natchiar SK,Klaholz BP

更新日期：2015-04-30 00:00:00

abstract：:The characterization of HIV-1 (HTLV-III/LAV), the human retrovirus associated with AIDS (acquired immune deficiency syndrome) has led to the identification of a group of related human and simian retroviruses which also infect CD4-bearing T lymphocytes. Simian T-lymphotropic virus type III (simian immodeficiency virus)...

journal_title：Nature

authors： Franchini G,Gurgo C,Guo HG,Gallo RC,Collalti E,Fargnoli KA,Hall LF,Wong-Staal F,Reitz MS Jr

更新日期：1987-08-06 00:00:00

abstract：:The current outbreak of coronavirus disease-2019 (COVID-19) poses unprecedented challenges to global health1. The new coronavirus responsible for this outbreak-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-shares high sequence identity to SARS-CoV and a bat coronavirus, RaTG132. Although bats may be the...

journal_title：Nature

authors： Xiao K,Zhai J,Feng Y,Zhou N,Zhang X,Zou JJ,Li N,Guo Y,Li X,Shen X,Zhang Z,Shu F,Huang W,Li Y,Zhang Z,Chen RA,Wu YJ,Peng SM,Huang M,Xie WJ,Cai QH,Hou FH,Chen W,Xiao L,Shen Y

更新日期：2020-07-01 00:00:00

abstract：:Oocytes arrested in the G2 phase of the cell cycle contain a p34cdc2/cyclin B complex which is kept in an inactive form by phosphorylation of its p34cdc2 subunit on tyrosine, threonine and perhaps serine residues. The phosphatase(s) involved in p34cdc2 dephosphorylation is unknown, but the product of the fission yeast...

journal_title：Nature

authors： Strausfeld U,Labbé JC,Fesquet D,Cavadore JC,Picard A,Sadhu K,Russell P,Dorée M

更新日期：1991-05-16 00:00:00

abstract：:During the evolution of the beta-globin family gene in vertebrates, different globin genes acquired different developmental patterns of expression. In mammals, specific 'embryonic' beta-like globins are synthesized in the earliest erythroid cells, which differentiate in the yolk sac of the embryo. In most mammals the ...

journal_title：Nature

authors： Chada K,Magram J,Costantini F

更新日期：1986-02-20 00:00:00

abstract：:Calcium influx through voltage-sensitive Ca2+ channels is the normal physiological stimulus for the activity-dependent release of neurotransmitters at synaptic contacts. It has been postulated that presynaptic inhibition of transmitter release is due to a reduction in Ca2+ influx at the nerve terminal, which could res...

journal_title：Nature

authors： Toth PT,Bindokas VP,Bleakman D,Colmers WF,Miller RJ

更新日期：1993-08-12 00:00:00

abstract：:Adsorption-based phenomena are important in gas separations, such as the treatment of greenhouse-gas and toxic-gas pollutants, and in water-adsorption-based heat pumps for solar cooling systems. The ability to tune the pore size, shape and functionality of crystalline porous coordination polymers--or metal-organic fra...

journal_title：Nature

authors： Krause S,Bon V,Senkovska I,Stoeck U,Wallacher D,Többens DM,Zander S,Pillai RS,Maurin G,Coudert FX,Kaskel S

更新日期：2016-04-21 00:00:00

abstract：:Tobacco smoking causes lung cancer1-3, a process that is driven by more than 60 carcinogens in cigarette smoke that directly damage and mutate DNA4,5. The profound effects of tobacco on the genome of lung cancer cells are well-documented6-10, but equivalent data for normal bronchial cells are lacking. Here we sequence...

journal_title：Nature

authors： Yoshida K,Gowers KHC,Lee-Six H,Chandrasekharan DP,Coorens T,Maughan EF,Beal K,Menzies A,Millar FR,Anderson E,Clarke SE,Pennycuick A,Thakrar RM,Butler CR,Kakiuchi N,Hirano T,Hynds RE,Stratton MR,Martincorena I,Janes

更新日期：2020-02-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Else H

更新日期：2018-11-01 00:00:00