The Earth's 'hum' is driven by ocean waves over the continental shelves.

abstract：: ...

journal_title：Nature

authors：

更新日期：2018-10-01 00:00:00

abstract：:During attempts to select nonsecretory variants from 0.467.3, and Epstein-Barr virus-transformed human lymphoblastoid cell line that secretes small amounts of IgM lambda, we exposed the cells to UV light. Cells that survived the irradiation were subcultured and their supernatants were screened for immunoglobulin produ...

journal_title：Nature

authors： Rosén A,Klein G

更新日期：1983-11-10 00:00:00

abstract：:Major ice sheets were permanently established on Antarctica approximately 34 million years ago, close to the Eocene/Oligocene boundary, at the same time as a permanent deepening of the calcite compensation depth in the world's oceans. Until recently, it was thought that Northern Hemisphere glaciation began much later,...

journal_title：Nature

authors： Edgar KM,Wilson PA,Sexton PF,Suganuma Y

更新日期：2007-08-23 00:00:00

abstract：:gamma-Aminobutyric acid (GABA), a major inhibitory neurotransmitter in the mammalian nervous system, is known to operate bicuculline-sensitive Cl- channels through GABAA receptors and bicuculline-insensitive cation channels through GABAB receptors. Recent observations indicate that the retina may contain GABA receptor...

journal_title：Nature

authors： Feigenspan A,Wässle H,Bormann J

更新日期：1993-01-14 00:00:00

abstract：:The long-term exchange of volatile species (such as water, carbon, nitrogen and the noble gases) between deep Earth and surface reservoirs controls the habitability of the Earth's surface. The present-day volatile budget of the mantle reflects the integrated history of outgassing and retention of primordial volatiles ...

journal_title：Nature

authors： Parai R,Mukhopadhyay S

更新日期：2018-08-01 00:00:00

abstract：:RNA polymerase (Pol) II produces messenger RNA during transcription of protein-coding genes in all eukaryotic cells. The Pol II structure is known at high resolution from X-ray crystallography for two yeast species. Structural studies of mammalian Pol II, however, remain limited to low-resolution electron microscopy a...

journal_title：Nature

authors： Bernecky C,Herzog F,Baumeister W,Plitzko JM,Cramer P

更新日期：2016-01-28 00:00:00

abstract：:Pairwise recognition of splice sites as a result of a scanning mechanism is an attractive model to explain the coordination of vertebrate splicing. Such a mechanism would predict a polarity-of-site recognition in the scanned unit, but no evidence for a polarity gradient across introns has been found. We have suggested...

journal_title：Nature

authors： Niwa M,MacDonald CC,Berget SM

更新日期：1992-11-19 00:00:00

abstract：: ...

journal_title：Nature

authors：

更新日期：2018-11-01 00:00:00

abstract：:Endocytosis of the major histocompatibility complex (MHC)-encoded class I and class II molecules has been the subject of recent investigations. Class I molecules, which are key elements in T cell-mediated cytotoxicity, are differentially endocytosed by different cell types. Fibroblasts internalize their class I molecu...

journal_title：Nature

authors： Machy P,Truneh A,Gennaro D,Hoffstein S

更新日期：1987-08-20 00:00:00

abstract：:Oestrogens are involved in the growth, development and homeostasis of a number of tissues. The physiological effects of these steroids are mediated by a ligand-inducible nuclear transcription factor, the oestrogen receptor (ER). Hormone binding to the ligand-binding domain (LBD) of the ER initiates a series of molecul...

journal_title：Nature

authors： Brzozowski AM,Pike AC,Dauter Z,Hubbard RE,Bonn T,Engström O,Ohman L,Greene GL,Gustafsson JA,Carlquist M

更新日期：1997-10-16 00:00:00

abstract：:Three-wave mixing in nonlinear materials--the interaction of two light waves to produce a third--is a convenient way of generating new optical frequencies from common laser sources. However, the resulting optical conversion yield is generally poor, because the relative phases of the three interacting waves change cont...

journal_title：Nature

authors： Baudrier-Raybaut M,Haïdar R,Kupecek P,Lemasson P,Rosencher E

更新日期：2004-11-18 00:00:00

abstract：:Electric-field-induced charge separation (polarization) is the most fundamental manifestation of the interaction of light with matter and a phenomenon of great technological relevance. Nonlinear optical polarization produces coherent radiation in spectral ranges inaccessible by lasers and constitutes the key to ultima...

journal_title：Nature

authors： Sommer A,Bothschafter EM,Sato SA,Jakubeit C,Latka T,Razskazovskaya O,Fattahi H,Jobst M,Schweinberger W,Shirvanyan V,Yakovlev VS,Kienberger R,Yabana K,Karpowicz N,Schultze M,Krausz F

更新日期：2016-06-02 00:00:00

abstract：:In the unactivated Limulus sperm, a 60- micro m-long bundle of actin filaments crosslinked by the protein scruin is bent and twisted into a coil around the base of the nucleus. At fertilization, the bundle uncoils and fully extends in five seconds to support a finger of membrane known as the acrosomal process. This bi...

journal_title：Nature

authors： Schmid MF,Sherman MB,Matsudaira P,Chiu W

更新日期：2004-09-02 00:00:00

abstract：:Molecular processes that govern pathogenic features of erythrocyte invasion and cytoadherence in malaria are reliant on Plasmodium-specific Duffy-binding-like domains (DBLs). These cysteine-rich modules recognize diverse host cell-surface receptors during pathogenesis. DBLs of parasite erythrocyte-binding proteins med...

journal_title：Nature

authors： Singh SK,Hora R,Belrhali H,Chitnis CE,Sharma A

更新日期：2006-02-09 00:00:00

abstract：:In Drosophila, a large group of structural genes exhibit coordinate regulation, not because they function in a common developmental pathway but because they happen to reside on the X chromosome. These genes are subjected to the regulatory mechanism of dosage compensation which insures that their phenotypic products ar...

journal_title：Nature

authors： Belote JM,Lucchesi JC

更新日期：1980-06-19 00:00:00

abstract：:How environmental cues regulate adult stem cell and cancer cell activity through surface receptors is poorly understood. Angiopoietin-like proteins (ANGPTLs), a family of seven secreted glycoproteins, are known to support the activity of haematopoietic stem cells (HSCs) in vitro and in vivo. ANGPTLs also have importan...

journal_title：Nature

authors： Zheng J,Umikawa M,Cui C,Li J,Chen X,Zhang C,Huynh H,Kang X,Silvany R,Wan X,Ye J,Cantó AP,Chen SH,Wang HY,Ward ES,Zhang CC

更新日期：2012-05-30 00:00:00

abstract：:Considerable evidence points to a role for G1 cyclin-dependent kinase (CDK) in allowing the accumulation of E2F transcription factor activity and induction of the S phase of the cell cycle. Numerous experiments have also demonstrated a critical role for both Myc and Ras activities in allowing cell-cycle progression. H...

journal_title：Nature

authors： Leone G,DeGregori J,Sears R,Jakoi L,Nevins JR

更新日期：1997-05-22 00:00:00

abstract：:Non-volcanic tremor is a weak, extended duration seismic signal observed episodically on some major faults, often in conjunction with slow slip events. Such tremor may hold the key to understanding fundamental processes at the deep roots of faults, and could signal times of accelerated slip and hence increased seismic...

journal_title：Nature

authors： Shelly DR,Beroza GC,Ide S

更新日期：2007-03-15 00:00:00

abstract：:The structure of foot-and-mouth disease virus has been determined at close to atomic resolution by X-ray diffraction without experimental phase information. The virus shows similarities with other picornaviruses but also several unique features. The canyon or pit found in other picornaviruses is absent; this has impor...

journal_title：Nature

authors： Acharya R,Fry E,Stuart D,Fox G,Rowlands D,Brown F

更新日期：1989-02-23 00:00:00

abstract：:Since the early 1980s, most electronics have relied on the use of complementary metal-oxide-semiconductor (CMOS) transistors. However, the principles of CMOS operation, involving a switchable semiconductor conductance controlled by an insulating gate, have remained largely unchanged, even as transistors are miniaturiz...

journal_title：Nature

authors： Manipatruni S,Nikonov DE,Lin CC,Gosavi TA,Liu H,Prasad B,Huang YL,Bonturim E,Ramesh R,Young IA

更新日期：2019-01-01 00:00:00

abstract：:The brain has generally been considered an insulin-independent organ, because insulin does not apparently exert a direct effect on brain glucose consumption. Recently, however, insulin receptors have been detected throughout the central nervous system (CNS) of several species. Since important insights into the functio...

journal_title：Nature

authors： van Houten M,Posner BI

更新日期：1979-12-06 00:00:00

abstract：:Mammalian circadian clocks consist of complex integrated feedback loops that cannot be elucidated without comprehensive measurement of system dynamics and determination of network structures. To dissect such a complicated system, we took a systems-biological approach based on genomic, molecular and cell biological tec...

journal_title：Nature

authors： Ueda HR,Chen W,Adachi A,Wakamatsu H,Hayashi S,Takasugi T,Nagano M,Nakahama K,Suzuki Y,Sugano S,Iino M,Shigeyoshi Y,Hashimoto S

更新日期：2002-08-01 00:00:00

abstract：:The recent discovery of more than a thousand planets outside our Solar System, together with the significant push to achieve inertially confined fusion in the laboratory, has prompted a renewed interest in how dense matter behaves at millions to billions of atmospheres of pressure. The theoretical description of such ...

journal_title：Nature

authors： Smith RF,Eggert JH,Jeanloz R,Duffy TS,Braun DG,Patterson JR,Rudd RE,Biener J,Lazicki AE,Hamza AV,Wang J,Braun T,Benedict LX,Celliers PM,Collins GW

更新日期：2014-07-17 00:00:00

abstract：:Atlantic tropical cyclone activity, as measured by annual storm counts, reached anomalous levels over the past decade. The short nature of the historical record and potential issues with its reliability in earlier decades, however, has prompted an ongoing debate regarding the reality and significance of the recent ris...

journal_title：Nature

authors： Mann ME,Woodruff JD,Donnelly JP,Zhang Z

更新日期：2009-08-13 00:00:00

abstract：:Cells are eliminated in a variety of physiological settings by apoptosis, a genetically encoded process of cellular suicide. Apoptosis comprises an intrinsic cellular defence against tumorigenesis, which, when suppressed, may contribute to the development of malignancies. The bcl-2 oncogene, which is activated in foll...

journal_title：Nature

authors： Chittenden T,Harrington EA,O'Connor R,Flemington C,Lutz RJ,Evan GI,Guild BC

更新日期：1995-04-20 00:00:00

abstract：:Sea ice and dust flux increased greatly in the Southern Ocean during the last glacial period. Palaeorecords provide contradictory evidence about marine productivity in this region, but beyond one glacial cycle, data were sparse. Here we present continuous chemical proxy data spanning the last eight glacial cycles (740...

journal_title：Nature

authors： Wolff EW,Fischer H,Fundel F,Ruth U,Twarloh B,Littot GC,Mulvaney R,Röthlisberger R,de Angelis M,Boutron CF,Hansson M,Jonsell U,Hutterli MA,Lambert F,Kaufmann P,Stauffer B,Stocker TF,Steffensen JP,Bigler M,Siggaard-An

更新日期：2006-03-23 00:00:00

abstract：:Some bacteria are capable of extracellular electron transfer, thereby enabling them to use electron acceptors and donors without direct cell contact. Beyond the micrometre scale, however, no firm evidence has previously existed that spatially segregated biogeochemical processes can be coupled by electric currents in n...

journal_title：Nature

authors： Nielsen LP,Risgaard-Petersen N,Fossing H,Christensen PB,Sayama M

更新日期：2010-02-25 00:00:00

abstract：:Anthrax toxin, comprising protective antigen, lethal factor, and oedema factor, is the major virulence factor of Bacillus anthracis, an agent that causes high mortality in humans and animals. Protective antigen forms oligomeric prepores that undergo conversion to membrane-spanning pores by endosomal acidification, and...

journal_title：Nature

authors： Jiang J,Pentelute BL,Collier RJ,Zhou ZH

更新日期：2015-05-28 00:00:00

abstract：:Cornelia de Lange syndrome (CdLS) is a dominantly inherited congenital malformation disorder, caused by mutations in the cohesin-loading protein NIPBL for nearly 60% of individuals with classical CdLS, and by mutations in the core cohesin components SMC1A (~5%) and SMC3 (<1%) for a smaller fraction of probands. In hum...

journal_title：Nature

authors： Deardorff MA,Bando M,Nakato R,Watrin E,Itoh T,Minamino M,Saitoh K,Komata M,Katou Y,Clark D,Cole KE,De Baere E,Decroos C,Di Donato N,Ernst S,Francey LJ,Gyftodimou Y,Hirashima K,Hullings M,Ishikawa Y,Jaulin C,Kaur

更新日期：2012-09-13 00:00:00

abstract：:Evolutionary adaptation can be rapid and potentially help species counter stressful conditions or realize ecological opportunities arising from climate change. The challenges are to understand when evolution will occur and to identify potential evolutionary winners as well as losers, such as species lacking adaptive c...

journal_title：Nature

authors： Hoffmann AA,Sgrò CM

更新日期：2011-02-24 00:00:00