Complete mitochondrial genome of northern Indian red muntjac (Muntiacus vaginalis) and its phylogenetic analysis.

abstract：:Se is an essential trace element and is found as a selenocysteine in the active site of Se-enzymes, such as glutathione peroxidase. tRNASec is first aminoacylated with serine by Ser RS and further is converted to selenocysteyl-tRNA by selenocysteine synthase. Mammalian selenocysteine tRNA has dual identities with Ser ...

journal_title：Molecular biology reports

authors： Mizutani T,Kanaya K,Ikeda S,Fujiwara T,Yamada K,Totsuka T

更新日期：1998-11-01 00:00:00

abstract：:Dipeptidyl peptidase III (DPP III) is an emerging biomarker of human cancers. Expression, specificity, and function of human DPP III (hDPP III) mRNA variant I (V-I), II (V-II), and III (V-III) are poorly understood. Here, we investigated expression of these variants in multiple human tumor derived cell lines. DNA sequ...

journal_title：Molecular biology reports

authors： Prajapati SC,Chauhan SS

更新日期：2016-06-01 00:00:00

abstract：:Recent studies suggest that the common variant in the GSTM1 and GSTT1 genes modifies the risk of coronary artery disease (CAD), however, it is unclear whether the risk of CAD modulated by variants in the GSTM1 and GSTT1 genes was associated with alterations of indices of oxidative stress and inflammation. Our study is...

journal_title：Molecular biology reports

authors： Tang JJ,Wang MW,Jia EZ,Yan JJ,Wang QM,Zhu J,Yang ZJ,Lu X,Wang LS

更新日期：2010-01-01 00:00:00

abstract：:The product of the OTUB1 gene is a member of the OTU superfamily of predicted cysteine proteases and inhibits cytokine gene transcription via its interaction with a ubiquitin protease and E3 ubiquitin ligase. To further understand the functions of the porcine OTUB1 gene, the subcellular localization of porcine OTUB1 p...

journal_title：Molecular biology reports

authors： Shan TL,Tang ZL,Guo DZ,Yang SL,Mu YL,Ma YH,Guan WJ,Li K

更新日期：2009-07-01 00:00:00

abstract：:This study investigated the role of the mevalonate pyrophosphate decarboxylase gene in the triterpene biosynthetic pathway of Ganoderma lucidum. The mevalonate pyrophosphate decarboxylase gene (mvd) was isolated using a degenerate primer-PCR technique. An analysis of the Gl-mvd transcription profile revealed a positiv...

journal_title：Molecular biology reports

authors： Shi L,Qin L,Xu Y,Ren A,Fang X,Mu D,Tan Q,Zhao M

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:It is reported that parental exposure to toxicants can influence offspring sex ratio at birth. Studies have reported that several chemicals found in cigarette smoke are substrates of glutathione S-transferase T1 (GSTT1, a member of GSTtheta). To determine the effect of cigarette smoke on serum levels of test...

journal_title：Molecular biology reports

authors： Saadat M

更新日期：2009-07-01 00:00:00

abstract：:Intramembrane proteases control many important processes in a wide variety of organisms through regulated intramembrane proteolysis (RIP). However, very few intramembrane proteases have been characterized in plants. Intriguingly, EGY2 in Arabidopsis belongs to the Site-2 protease (S2P) family that performs RIP. It con...

journal_title：Molecular biology reports

authors： Chen G,Law K,Ho P,Zhang X,Li N

更新日期：2012-03-01 00:00:00

abstract：:Although there are many studies on the role of PI3K/AKT/mTOR pathway and autophagy genes in the mechanism of head and neck cancer formation and prognostic significance, there is no study investigating the role of the genes in paranasal sinus carcinomas. The aim of the study was to assess the role of the PI3K/AKT/mTOR ...

journal_title：Molecular biology reports

authors： Biray Avci C,Sezgin B,Goker Bagca B,Karci HB,Gode S

更新日期：2020-05-01 00:00:00

abstract：:Large-scale random cDNA sequencing projects have been started for several organisms and are a valuable tool for the analysis of quantitative and qualitative aspects of gene expression. However, the reliability of the obtained data is limited as most of the clones are only partially analysed on one strand. As a consequ...

journal_title：Molecular biology reports

authors： Braun HP

更新日期：1996-01-01 00:00:00

abstract：:Alterations in expression of the DFF40 gene have been reported in some cancers. This study is an in vitro study of the therapeutic effects of gene transfer that lead to elevation in DFF40 expression within T-47D cells in the presence of sulfonamide drugs. In this study, we have constructed a eukaryotic expression vect...

journal_title：Molecular biology reports

authors： Bagheri F,Safarian S,Eslaminejad MB,Sheibani N

更新日期：2014-11-01 00:00:00

abstract：:TopBP1 protein displays structural as well as functional similarities to BRCA1 and is involved in DNA replication, DNA damage checkpoint response and transcriptional regulation. Aberrant expression of TopBP1 may lead to genomic instability and can have pathological consequences. In this study we aimed to investigate e...

journal_title：Molecular biology reports

authors： Forma E,Krzeslak A,Bernaciak M,Romanowicz-Makowska H,Brys M

更新日期：2012-07-01 00:00:00

abstract：:GASA-like genes form multigene families in diverse plant species and encode the proteins with a unique cysteine-rich domain (GASA domain). In our previously work, we cloned a GASA-like gene PRGL (Proline-rich GASA-like) from gerbera. Here we report the expression profiles of PRGL and the subcellular localization of PR...

journal_title：Molecular biology reports

authors： Peng J,Lai L,Wang X

更新日期：2010-10-01 00:00:00

abstract：:Proto-oncogen Ahi-1 is closely related to a lot of human and mouse diseases. Ahi-1 mutation will lead to leukemia in mice and Joubert syndrome in human beings. We have cloned the full cDNA sequence of Ahi-1 homologous in zebrafish, and RT-PCR results of ZAhi-1 in different tissues reveal that ZAhi-1 expressed highest ...

journal_title：Molecular biology reports

authors： Zhou W,Song P

更新日期：2006-06-01 00:00:00

abstract：:Emergence of MDR 'superbugs' inflamed a severe sense of urgency amongst scientists aiming at the discovery of novel potential drug molecules. Bacteria of the genus Streptomyces are really worth investigating for their immense potential to produce natural compounds of pharmaceutical importance. In the present study, th...

journal_title：Molecular biology reports

authors： Kumar P,Chauhan A,Kumar M,Kuanr BK,Solanki R,Kapur MK

更新日期：2020-09-01 00:00:00

abstract：:As-ClC (chloride channels protein from Artemia sinica), a member from the chloride channels protein family, is a α-helical membrane protein predicted to traverse the cell membrane 11 times. It is important for several physiological functions such as cell volume regulation, cell proliferation, growth and differentiatio...

journal_title：Molecular biology reports

authors： Zhang Q,Hou M,Li Q,Han L,Yuan Z,Tan J,Du B,Zou X,Hou L

更新日期：2013-05-01 00:00:00

abstract：:The human dopamine transporter gene (hDAT) encodes the dopamine transporter in dopamine (DA) neurons to regulate DA transmission. hDAT expression varies significantly from neuron to neuron, and from individual to individual so that dysregulation of hDAT is related to many neuropsychiatric disorders. It is critical to ...

journal_title：Molecular biology reports

authors： Zhao Y,Zhou Y,Xiong N,Lin Z

更新日期：2012-05-01 00:00:00

abstract：:The Pro12Ala and C161T polymorphisms in peroxisome proliferator-activated receptor γ (PPARγ) have been shown to be associated with carotid artery atherosclerosis. It remains unclear whether these two polymorphisms are associated with risk factors for cardiovascular disease (CVD) in hemodialysis (HD) patients. Therefor...

journal_title：Molecular biology reports

authors： Liu F,Mei X,Zhang Y,Qi H,Wang J,Wang Y,Jiang W,Zhang X,Yan H,Zhuang S

更新日期：2014-11-01 00:00:00

abstract：:The protease activity of gp63 from L. major was studied in relation to tunicamycin induced N-deglycosylation. It was found that after tunicamycin treatment, a N-deglycosylated product of gp63 with protease activity is present at the cell surface of Leishmania promastigote. ...

journal_title：Molecular biology reports

authors： Hernandez C,Manenti S,Hernandez AG

更新日期：1992-05-01 00:00:00

abstract：:Mitochondrial disorders are a frequent cause of neurological disability affecting children and adults. Traditionally, molecular diagnosis of mitochondrial diseases was mostly accomplished by the use of Sanger sequencing and PCR-RFLP. However, there are particular drawbacks associated with the use of these methods. Rec...

journal_title：Molecular biology reports

authors： Kauffman MA,Gonzlez-Morón D,Consalvo D,Westergaard G,Vazquez M,Mancini E,Taratuto AL,Rey R,Kochen S

更新日期：2012-06-01 00:00:00

abstract：:Molluscs are an extraordinarily diverse group of animals and to discriminate them based on one molecular marker/gene is very difficult because of the too fast or slow rate of nucleotide substitution. In the study, the tropomyosin cds (coding sequences) of 43 animal species were analyzed, the results of which suggested...

journal_title：Molecular biology reports

authors： Wang X,Li L,Xu F,Zhang G

更新日期：2011-10-01 00:00:00

abstract：:The q11.2 region on chromosome 22 contains numerous low-copy repeats that lead to deleted or duplicated regions in the chromosome, thereby resulting in different syndromes characterized by intellectual disabilities or congenital anomalies. The association between patient phenotypes and 22q11.2 copy number abnormalitie...

journal_title：Molecular biology reports

authors： Cai M,Lin N,Su L,Wu X,Xie X,Li Y,Lin Y,Huang H,Xu L

更新日期：2020-10-01 00:00:00

abstract：:Growth-regulating factor (GRF) is an important protein in GA-mediated response, with key roles in plant growth and development. However, it is not known whether or how the GRF proteins in citrus to regulate organ size. In this study, nine citrus GRF genes (CsGRF1-9) were validated from the 'Anliu' sweet orange (AL, Ci...

journal_title：Molecular biology reports

authors： Liu X,Guo LX,Jin LF,Liu YZ,Liu T,Fan YH,Peng SA

更新日期：2016-10-01 00:00:00

abstract：:RNA polymerase III in an extract of HeLa cells transcribes RNA 5S in size from genomic bovine DNA template. This RNA represents a major fraction of the RNA synthesized. 5S RNA is not transcribed from bovine chromatin at equivalent concentrations and RNA the size of tRNA or tRNA precursor is not detected. At low UTP co...

journal_title：Molecular biology reports

authors： Furth JJ,Su CY

更新日期：1983-08-01 00:00:00

abstract：:Telomerase activity is repressed in normal human somatic cells, but is activated in most cancers, suggesting that telomerase may be an important target for cancer therapy. Agents that interact selectively with telomerase are anticipated to exert specific action on cancer cells. In this study, we evaluated maleimide de...

journal_title：Molecular biology reports

authors： Huang PR,Yeh YM,Pao CC,Chen CY,Wang TC

更新日期：2012-09-01 00:00:00

abstract：:Familial hypercholesterolemia (FH) (OMIM 143890) is an autosomal dominantly inherited disease mainly caused by mutations of the gene encoding the low density lipoprotein receptor (LDLR) and Apolipoprotein (Apo) B. First the common mutation R3500Q in ApoB gene was determined using PCR/RFLP method. Then the LDLR gene wa...

journal_title：Molecular biology reports

authors： Cheng X,Ding J,Zheng F,Zhou X,Xiong C

更新日期：2009-11-01 00:00:00

abstract：:Groups of CBA mice were administered [35S] methionine (1 mCi/mouse). Non-histone proteins, H1 and H1(0) histones and nucleosomal core histones were isolated from different issues by selective extractions. The measurements of radioactivity of individual bands and autoradiography of dry gels were used to identify methio...

journal_title：Molecular biology reports

authors： Medvedev ZA,Medvedeva MN

更新日期：1988-01-01 00:00:00

abstract：:The kelch-repeat protein family is a recently found new kind of actin-binding protein. It is characterized by tandemly arranged motifs of about 50 amino acids. Previous study showed that most members of the kelch-repeat family were cytoskeletal proteins implicated in various cellular processes, such as actin cytoskele...

journal_title：Molecular biology reports

authors： Xu J,Gu S,Wang S,Dai J,Ji C,Jin Y,Qian J,Wang L,Ye X,Xie Y,Mao Y

更新日期：2003-12-01 00:00:00

abstract：:Spermiogenesis is a developmental process undergoing continuous differentiation to drive a diploid spermatogonium towards a haploid sperm cell. This striking transformation from spermatogonium to spermatozoa is made possible by the stage-specific adaption of cytoskeleton and associated molecular motor proteins. KIFC1 ...

journal_title：Molecular biology reports

authors： Wang YT,Mao H,Hou CC,Sun X,Wang DH,Zhou H,Yang WX

更新日期：2012-07-01 00:00:00

abstract：:Circulating long noncoding RNAs as biomarkers of diseases have attracted increasing attention recently. However, circulating lncRNAs in hypertension is still unexplored niche. The levels of lncRNAs GAS5, NR024118, MRAK134679, AX765700 and MRNR026574 were measured in the serum and myocardium of hypertensive rats and no...

journal_title：Molecular biology reports

authors： Wu Y,Zhang Z,Ren S,Li K,Ning Q,Jiang X

更新日期：2019-12-01 00:00:00

abstract：:A cDNA encoding an O-methyltransferase (namely FGCOMT1) was identified from the medicinal plant Trigonella foenum-graecum L. The FGCOMT1 enzyme is a functional caffeic acid O-methyltransferase (COMT) and is localized in the cytosol. Kinetic analysis indicated that FGCOMT1 protein exhibited the highest catalyzing effic...

journal_title：Molecular biology reports

authors： Qin JC,Zhang YM,Lang CY,Yao YH,Pan HY,Li X

更新日期：2012-02-01 00:00:00