A living display system resolved pixel by pixel.

abstract：:A quantum internet that connects remote quantum processors1,2 should enable a number of revolutionary applications such as distributed quantum computing. Its realization will rely on entanglement of remote quantum memories over long distances. Despite enormous progress3-12, at present the maximal physical separation a...

journal_title：Nature

authors： Yu Y,Ma F,Luo XY,Jing B,Sun PF,Fang RZ,Yang CW,Liu H,Zheng MY,Xie XP,Zhang WJ,You LX,Wang Z,Chen TY,Zhang Q,Bao XH,Pan JW

更新日期：2020-02-01 00:00:00

abstract：:To artists, the face is a mirror of the soul. To biologists, the face reflects remarkable structural diversity--think of bulldogs and wolfhounds or galapagos finches. How do such variations in skeletal form arise? Do the same mechanisms control skeletogenesis elsewhere in the body? The answers lie in the molecular mac...

journal_title：Nature

authors： Helms JA,Schneider RA

更新日期：2003-05-15 00:00:00

abstract：:A psychotherapeutic regimen that uses alternating bilateral sensory stimulation (ABS) has been used to treat post-traumatic stress disorder. However, the neural basis that underlies the long-lasting effect of this treatment-described as eye movement desensitization and reprocessing-has not been identified. Here we des...

journal_title：Nature

authors： Baek J,Lee S,Cho T,Kim SW,Kim M,Yoon Y,Kim KK,Byun J,Kim SJ,Jeong J,Shin HS

更新日期：2019-02-01 00:00:00

abstract：:The travelling salesman problem is a classical problem in the field of combinatorial optimization, concerned with efficient methods for maximizing or minimizing a function of many independent variables. Given the positions of N cities, which in the simplest case lie in the plane, what is the shortest closed tour in wh...

journal_title：Nature

authors： Durbin R,Willshaw D

更新日期：1987-04-16 00:00:00

abstract：:Expression of Ets2, a proto-oncogene and transcription factor, occurs in a variety of cell types. During murine development it is highly expressed in newly forming cartilage, including in the skull precursor cells and vertebral primordia. Ets2 is located on human chromosome 21 (ref. 8) and is overexpressed in Down's s...

journal_title：Nature

authors： Sumarsono SH,Wilson TJ,Tymms MJ,Venter DJ,Corrick CM,Kola R,Lahoud MH,Papas TS,Seth A,Kola I

更新日期：1996-02-08 00:00:00

abstract：:SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) and Rab-GTPases, together with their cofactors, mediate the attachment step in the membrane fusion of vesicles. But how bilayer mixing--the subsequent core process of fusion--is catalysed remains unclear. Ca2+/calmodulin controls this term...

journal_title：Nature

authors： Peters C,Bayer MJ,Bühler S,Andersen JS,Mann M,Mayer A

更新日期：2001-02-01 00:00:00

abstract：:The RNA polymerase elongation complex (EC) is both highly stable and processive, rapidly extending RNA chains for thousands of nucleotides. Understanding the mechanisms of elongation and its regulation requires detailed information about the structural organization of the EC. Here we report the 2.5-A resolution struct...

journal_title：Nature

authors： Vassylyev DG,Vassylyeva MN,Perederina A,Tahirov TH,Artsimovitch I

更新日期：2007-07-12 00:00:00

abstract：:Aneuploidy, referring here to genome contents characterized by abnormal numbers of chromosomes, has been associated with developmental defects, cancer and adaptive evolution in experimental organisms. However, it remains unresolved how aneuploidy impacts gene expression and whether aneuploidy could directly bring abou...

journal_title：Nature

authors： Pavelka N,Rancati G,Zhu J,Bradford WD,Saraf A,Florens L,Sanderson BW,Hattem GL,Li R

更新日期：2010-11-11 00:00:00

abstract：:RNA polymerase II (RNAP II) is responsible for transcribing all messenger RNAs in eukaryotic cells during a highly regulated process that is conserved from yeast to human, and that serves as a central control point for cellular function. Here we investigate the transcription dynamics of single RNAP II molecules from S...

journal_title：Nature

authors： Galburt EA,Grill SW,Wiedmann A,Lubkowska L,Choy J,Nogales E,Kashlev M,Bustamante C

更新日期：2007-04-12 00:00:00

abstract：:Sensory neuroscience seeks to understand how the brain encodes natural environments. However, neural coding has largely been studied using simplified stimuli. In order to assess whether the brain's coding strategy depends on the stimulus ensemble, we apply a new information-theoretic method that allows unbiased calcul...

journal_title：Nature

authors： Sharpee TO,Sugihara H,Kurgansky AV,Rebrik SP,Stryker MP,Miller KD

更新日期：2006-02-23 00:00:00

abstract：:A major problem in the elucidation of the molecular mechanisms governing development is the distinction between direct and indirect regulatory interactions among developmental control genes. In vivo studies have indicated that the Drosophila segmentation gene fushi tarazu (ftz) directly or indirectly autoregulates its...

journal_title：Nature

authors： Schier AF,Gehring WJ

更新日期：1992-04-30 00:00:00

abstract：:Quantum simulation--the use of one quantum system to simulate a less controllable one--may provide an understanding of the many quantum systems which cannot be modelled using classical computers. Considerable progress in control and manipulation has been achieved for various quantum systems, but one of the remaining c...

journal_title：Nature

authors： Wilson AC,Colombe Y,Brown KR,Knill E,Leibfried D,Wineland DJ

更新日期：2014-08-07 00:00:00

abstract：:Ferroptosis-an iron-dependent, non-apoptotic cell death process-is involved in various degenerative diseases and represents a targetable susceptibility in certain cancers1. The ferroptosis-susceptible cell state can either pre-exist in cells that arise from certain lineages or be acquired during cell-state transitions...

journal_title：Nature

authors： Zou Y,Henry WS,Ricq EL,Graham ET,Phadnis VV,Maretich P,Paradkar S,Boehnke N,Deik AA,Reinhardt F,Eaton JK,Ferguson B,Wang W,Fairman J,Keys HR,Dančík V,Clish CB,Clemons PA,Hammond PT,Boyer LA,Weinberg RA,Schreiber

更新日期：2020-09-01 00:00:00

abstract：:Intracellular signalling following mitogenic stimulation of quiescent cells involves the initiation of a phosphorylation cascade that leads to the rapid and reversible activation of the mitogen-activated protein (MAP) kinases ERK1 and ERK2. MAP kinase activation is mediated by dual phosphorylation within the motif Thr...

journal_title：Nature

authors： Ward Y,Gupta S,Jensen P,Wartmann M,Davis RJ,Kelly K

更新日期：1994-02-17 00:00:00

abstract：:The idea that natural selection on genes might be detected using only a single genome has been put forward by Plotkin and colleagues, who present a method that they claim can detect selection without the need for comparative data and which, if correct, would confer greater power of analysis with less information. Here...

journal_title：Nature

authors： Hahn MW,Mezey JG,Begun DJ,Gillespie JH,Kern AD,Langley CH,Moyle LC

更新日期：2005-01-20 00:00:00

abstract：:Protein-tyrosine phosphatases (PTPs) are vital for regulating tryosine phosphorylation in many processes, including growth and differentiation. The regulation of receptor-like PTP (RPTP) activity remains poorly understood, but based on the crystal structure of RPTPalpha domain 1 we have proposed that dimerization can ...

journal_title：Nature

authors： Jiang G,den Hertog J,Su J,Noel J,Sap J,Hunter T

更新日期：1999-10-07 00:00:00

abstract：:Trophic control over the expression and membrane distribution of voltage-dependent ion channels is one of the principal organizing events underlying the maturation of excitable cells. The myelin sheath is a major structural determinant of regional ion channel topography in central axons, but the exact molecular signal...

journal_title：Nature

authors： Noebels JL,Marcom PK,Jalilian-Tehrani MH

更新日期：1991-08-01 00:00:00

abstract：:Gram-negative bacteria, such as Escherichia coli, expel toxic chemicals through tripartite efflux pumps that span both the inner and outer membrane. The three parts are an inner membrane, substrate-binding transporter; a membrane fusion protein; and an outer-membrane-anchored channel. The fusion protein connects the t...

journal_title：Nature

authors： Su CC,Long F,Zimmermann MT,Rajashankar KR,Jernigan RL,Yu EW

更新日期：2011-02-24 00:00:00

abstract：:The female germ line undergoes a unique sequence of differentiation processes that confers totipotency to the egg. The reconstitution of these events in vitro using pluripotent stem cells is a key achievement in reproductive biology and regenerative medicine. Here we report successful reconstitution in vitro of the en...

journal_title：Nature

authors： Hikabe O,Hamazaki N,Nagamatsu G,Obata Y,Hirao Y,Hamada N,Shimamoto S,Imamura T,Nakashima K,Saitou M,Hayashi K

更新日期：2016-11-10 00:00:00

abstract：:Sodium channels in plasma membranes can be blocked by a large variety of toxins and local anaesthetics. This property, however, is not confined to relatively large molecules. For instance, extracellularly applied small ions like hydrogen may also prevent the passive transport of permeant cations across open Na+ channe...

journal_title：Nature

authors： Wanke E,Carbone E,Testa PL

更新日期：1980-09-04 00:00:00

abstract：:Stearoyl-CoA desaturase (SCD) is conserved in all eukaryotes and introduces the first double bond into saturated fatty acyl-CoAs. Because the monounsaturated products of SCD are key precursors of membrane phospholipids, cholesterol esters and triglycerides, SCD is pivotal in fatty acid metabolism. Humans have two SCD ...

journal_title：Nature

authors： Bai Y,McCoy JG,Levin EJ,Sobrado P,Rajashankar KR,Fox BG,Zhou M

更新日期：2015-08-13 00:00:00

abstract：:Saturn's largest moon, Titan, remains an enigma, explored only by remote sensing from Earth, and by the Voyager and Cassini spacecraft. The most puzzling aspects include the origin of the molecular nitrogen and methane in its atmosphere, and the mechanism(s) by which methane is maintained in the face of rapid destruct...

journal_title：Nature

authors： Niemann HB,Atreya SK,Bauer SJ,Carignan GR,Demick JE,Frost RL,Gautier D,Haberman JA,Harpold DN,Hunten DM,Israel G,Lunine JI,Kasprzak WT,Owen TC,Paulkovich M,Raulin F,Raaen E,Way SH

更新日期：2005-12-08 00:00:00

abstract：:Endogenous retroviruses (ERVs) are abundant and heterogenous groups of integrated retroviral sequences that affect genome regulation and cell physiology throughout their RNA-centred life cycle1. Failure to repress ERVs is associated with cancer, infertility, senescence and neurodegenerative diseases2,3. Here, using an...

journal_title：Nature

authors： Chelmicki T,Roger E,Teissandier A,Dura M,Bonneville L,Rucli S,Dossin F,Fouassier C,Lameiras S,Bourc'his D

更新日期：2021-01-13 00:00:00

abstract：:Spectacular fossils from the Early Cretaceous Jehol Group of northeastern China have greatly expanded our knowledge of the diversity and palaeobiology of dinosaurs and early birds, and contributed to our understanding of the origin of birds, of flight, and of feathers. Pennaceous (vaned) feathers and integumentary fil...

journal_title：Nature

authors： Zhang F,Kearns SL,Orr PJ,Benton MJ,Zhou Z,Johnson D,Xu X,Wang X

更新日期：2010-02-25 00:00:00

abstract：:Nucleosomes cover most of the genome and are thought to be displaced by transcription factors in regions that direct gene expression. However, the modes of interaction between transcription factors and nucleosomal DNA remain largely unknown. Here we systematically explore interactions between the nucleosome and 220 tr...

journal_title：Nature

authors： Zhu F,Farnung L,Kaasinen E,Sahu B,Yin Y,Wei B,Dodonova SO,Nitta KR,Morgunova E,Taipale M,Cramer P,Taipale J

更新日期：2018-10-01 00:00:00

abstract：:The T-cell receptor (TCR) repertoire is selected in the thymus after rearrangement of genes encoding TCR alpha and beta chains. Selection is based on the recognition by newly emergent T cells of self-ligands associated with molecules of the major histocompatibility complex: some combinations result in positive selecti...

journal_title：Nature

authors： Dyson PJ,Knight AM,Fairchild S,Simpson E,Tomonari K

更新日期：1991-02-07 00:00:00

abstract：: ...

journal_title：Nature

authors：

更新日期：2019-01-01 00:00:00

abstract：:A newly-constructed antibody-like molecule containing the gp120-binding domain of the receptor for human immunodeficiency virus blocks HIV-1 infection of T cells and monocytes. Its long plasma half-life, other antibody-like properties, and potential to block all HIV isolates, make it a good candidate for therapeutic u...

journal_title：Nature

authors： Capon DJ,Chamow SM,Mordenti J,Marsters SA,Gregory T,Mitsuya H,Byrn RA,Lucas C,Wurm FM,Groopman JE

更新日期：1989-02-09 00:00:00

abstract：:Most of the progress in human culture has required the exploitation of energy resources. About 100 years ago, the major source of energy shifted from recent solar to fossil hydrocarbons, including liquid and gaseous petroleum. Technology has generally led to a greater use of hydrocarbon fuels for most human activities...

journal_title：Nature

authors： Hall C,Tharakan P,Hallock J,Cleveland C,Jefferson M

更新日期：2003-11-20 00:00:00

abstract：:The biochemical response to food intake must be precisely regulated. Because ingested sugars and fats can feed into many anabolic and catabolic pathways1, how our bodies handle nutrients depends on strategically positioned metabolic sensors that link the intrinsic nutritional value of a meal with intermediary metaboli...

journal_title：Nature

authors： He S,Kahles F,Rattik S,Nairz M,McAlpine CS,Anzai A,Selgrade D,Fenn AM,Chan CT,Mindur JE,Valet C,Poller WC,Halle L,Rotllan N,Iwamoto Y,Wojtkiewicz GR,Weissleder R,Libby P,Fernández-Hernando C,Drucker DJ,Nahrendorf

更新日期：2019-02-01 00:00:00