Abstract：
:The idea that natural selection on genes might be detected using only a single genome has been put forward by Plotkin and colleagues, who present a method that they claim can detect selection without the need for comparative data and which, if correct, would confer greater power of analysis with less information. Here we argue that their method depends on assumptions that confound their conclusions and that, even if these assumptions were valid, the authors' inferences about adaptive natural selection are unjustified.
journal_name
Naturejournal_title
Natureauthors
Hahn MW,Mezey JG,Begun DJ,Gillespie JH,Kern AD,Langley CH,Moyle LCdoi
10.1038/nature03221keywords:
subject
Has Abstractpub_date
2005-01-20 00:00:00pages
E5-6; discussion E7-8issue
7023eissn
0028-0836issn
1476-4687pii
nature03221journal_volume
433pub_type
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