The N-terminal polypeptide derived from vMIP-II exerts its anti-tumor activity in human breast cancer by regulating lncRNA SPRY4-IT1.

abstract：:Epilepsy is a common neurological disorder that affects mammalian species including human beings and dogs. In order to discover novel drugs for the treatment of canine epilepsy, multiomics data were analyzed to identify epilepsy associated genes. In this research, the original ranking of associated genes was obtained ...

journal_title：Bioscience reports

authors： Wang S,Meng X,Wang Y,Liu Y,Xia J

更新日期：2019-09-06 00:00:00

abstract：:Corneal inflammation or keratitis is a significant cause of ocular morbidity around the world. Fortunately, the majority of the cases are successfully managed with medical therapy, but the failure of therapy does occur, leading to devastating consequences of either losing the vision or the eye. This review attempts to...

journal_title：Bioscience reports

authors： Sharma S

更新日期：2001-08-01 00:00:00

abstract：:Peanut (Arachis hypogaea) seed lectin, PNA is widely used to identify tumor specific antigen (T-antigen), Galbeta1-3GalNAc on the eukaryotic cell surface. The functional amino acid coding region of a cDNA clone, pBSH-PN was PCR amplified and cloned downstream of the polyhedrin promoter in the Autographa californica nu...

journal_title：Bioscience reports

authors： Kumar M,Behera AK,Kumar S,Srinivas VR,Das HR,Surolia A,Das RH

更新日期：1999-06-01 00:00:00

abstract：:Background: Urotensin-II (UII) rs228648 polymorphism has been reported to be associated with the risk of diabetes mellitus (DM) with inconsistent results. The present study sought to reassess the relationship between this polymorphism and susceptibility to DM by meta-analysis.Methods: Relevant eligible studies and who...

journal_title：Bioscience reports

authors： Zhao Y,Fang S,Que K,Xu G,Zhang H,Qi C,Yang N

更新日期：2018-12-07 00:00:00

abstract：:Mitochondrial genome is a powerful molecule marker to provide information for phylogenetic relationships and revealing molecular evolution in ichthyological studies. Sebastiscus species, a marine rockfish, are of essential economic value. However, the taxonomic status and phylogenetic relationships of Sebastidae have ...

journal_title：Bioscience reports

authors： Jia C,Zhang X,Xu S,Yang T,Yanagimoto T,Gao T

更新日期：2020-12-23 00:00:00

abstract：:The kinetics of the fusion process between erythrocyte ghosts, as induced by Sendai virus, were readily revealed by a simple fluorescence procedure previously employed to characterize the fusion of viruses with biological membranes. The method relies on the relief of fluorescence selfquenching of the membrane-inserted...

journal_title：Bioscience reports

authors： Hoekstra D,Klappe K

更新日期：1986-11-01 00:00:00

abstract：:We investigated the possible translational role which elevated concentrations of highly purified Semliki Forest virus (SFV) capsid (C)-protein molecules may play in a cell-free translation system. Here we demonstrate that in the absence of double-stranded RNA high concentrations of C protein triggered the phosphorylat...

journal_title：Bioscience reports

authors： Favre D,Studer E,Michel MR

更新日期：1996-12-01 00:00:00

abstract：:The effect of carbamylcholine and the calcium ionophore A23187 on catecholamine release and intracellular free calcium, [Ca2+]i, in bovine adrenal chromaffin cells was determined. At 10(-4) M carbamylcholine maximal release occurred with an accompanying increase in [Ca2+]i from a basal level of 168 nM to less than 300...

journal_title：Bioscience reports

authors： Burgoyne RD

更新日期：1984-07-01 00:00:00

abstract：:It is well known that the amino acids in the blood are distributed between the plasma and inside the cells. This study was conducted to determine whether amino acids can be located adsorbed on blood cell membranes. The amino acid concentration in the deproteinized haemolysed blood was higher than that in the fraction ...

journal_title：Bioscience reports

authors： Picó C,Pons A,Palou A

更新日期：1991-08-01 00:00:00

abstract：:The discovery of genes that control cell division in yeast, and their relation to cancer, is reviewed. ...

journal_title：Bioscience reports

authors： Hartwell LH

更新日期：2002-06-01 00:00:00

abstract：:The tetracycline repressor (TetR)-regulated system is a widely used tool to study gene functions through control of its expression. Various effectors such as tetracycline (Tc) and doxycycline (Dox) quickly induce or shut down gene expression, but reversing gene expression has not been eligible due to long half-lives o...

journal_title：Bioscience reports

authors： Song C,Kim N,Park M,Lee J,Oh KB,Sim T

更新日期：2019-01-08 00:00:00

abstract：:LGMD (limb-girdle muscular dystrophy) and CMD (congenital muscular dystrophy) are two common forms of neuromuscular disorders which are distinguishable by their age of onset but with probably a similar underlying pathway. In the present study, we report immunohistochemical, Western-blot and genetic analyses in a large...

journal_title：Bioscience reports

authors： Hadj Salem I,Kamoun F,Louhichi N,Rouis S,Mziou M,Fendri-Kriaa N,Makni-Ayadi F,Triki C,Fakhfakh F

更新日期：2011-04-01 00:00:00

abstract：:Heparin causes lysis of the multilamellar liposomes of all three charges, positive, neutral, and negative, and thus releases the entrapped [3H]glucose or chromate. The lytic effect of heparin is also observed in liposomes prepared from the lipids extracted from human red blood cells. Heparin is found to interact with ...

journal_title：Bioscience reports

authors： Patel HM,Parvez N,Field J,Ryman BE

更新日期：1983-01-01 00:00:00

abstract：:Obesity is considered a global epidemic. Specifically, obesity during pregnancy programs an increased risk of the offspring developing metabolic disorders in addition to the adverse effects on the mother per se Large numbers of human and animal studies have demonstrated that the gut microbiota plays a pivotal role in ...

journal_title：Bioscience reports

authors： Zhou L,Xiao X

更新日期：2018-04-13 00:00:00

abstract：:Wilms tumor is the most common renal malignancy that occurs in children. TP53 gene is considered as a tumor-suppressing gene through controlling cell growth. TP53 gene rs1042522 C>G (Arg72Pro) polymorphism is widely investigated in various types of cancers. However, it is not established if TP53 rs1042522 C>G polymorp...

journal_title：Bioscience reports

authors： Liu P,Zhuo Z,Li W,Cheng J,Zhou H,He J,Zhang J,Wang J

更新日期：2019-01-22 00:00:00

abstract：:Tuberculosis (TB) is a chronic infectious disease that has been threatening public health for many years. Several studies have shown the relationship between the macrophage migration inhibitory factor (MIF)-794 CATT (MIF-794 CATT) microsatellite polymorphism and susceptibility to TB. However, the results remain inconc...

journal_title：Bioscience reports

authors： Ma M,Tao L,Liu A,Liang Z,Yang J,Peng Y,Dai X,Bai R,Ji Z,Jian M,Bao F

更新日期：2018-07-06 00:00:00

abstract：:Prostate cancer (PCa), the second most mortal cancer from developed countries, presents a high level of chemoresistance. There is emerging evidence underscores the critical role of autophagy in the onset, progression, and chemoresistance of PCa. In the present study, we investigated the possible role of a novel autoph...

journal_title：Bioscience reports

authors： Liu J,Chen Z,Guo J,Wang L,Liu X

更新日期：2019-08-23 00:00:00

abstract：:Fatty-acid synthesis has been measured in vivo with 3H2O in cafeteria-fed rats exhibiting diet-induced thermogenesis. Synthesis was decreased in brown adipose tissue, the liver, white adipose tissue, and the carcass of the cafeteria-fed animals compared to rats fed the normal stock diet. Whole-body synthesis was also ...

journal_title：Bioscience reports

authors： Rothwell NJ,Stock MJ,Trayhurn P

更新日期：1983-03-01 00:00:00

abstract：:The sites and extents of bisulphite-mediated deamination of cytidine residues in HeLa-cell 5.8 S rRNA within the 5.8 S / 28 S rRNA complex have been determined. Comparison of these data with equivalent data for isolated ('unbound') 5.8 S rRNA suggests that the conformation of several cytidine residues, including inter...

journal_title：Bioscience reports

authors： Kelly JM,Goddard JP

更新日期：1981-05-01 00:00:00

abstract：:Kinesin family member 14 (KIF14) is a member of kinesin family proteins which have been found to be dysregulated in various cancer types. However, the expression of KIF14 and its potential prognostic significance have not been investigated in cervical cancer. Real-time PCR was performed to assess the expression levels...

journal_title：Bioscience reports

authors： Wang W,Shi Y,Li J,Cui W,Yang B

更新日期：2016-04-05 00:00:00

abstract：:Information on the prevalence and type distribution of human papillomavirus (HPV) among Malaysian women is currently limited. The present study therefore aimed to provide an updated estimate on the prevalence and type distribution of HPV among Malaysian women with and without cervical cancer. Total DNA was isolated fr...

journal_title：Bioscience reports

authors： Tan SC,Ismail MP,Duski DR,Othman NH,Ankathil R

更新日期：2018-03-29 00:00:00

abstract：:Background: Ki67 has been a key role for the treatment options and prognosis evaluation in some kinds of tumors; however, the spatial expression of Ki67 in oral squamous cell carcinoma (OSCC) has not been fully-evaluated. Therefore, in the present study, we aimed to elucidate the prognosis value of Ki67 spatial expres...

journal_title：Bioscience reports

authors： Jing Y,Yang Y,Hao F,Song Y,Zhang X,Zhang Y,Huang X,Hu Q,Ni Y

更新日期：2018-11-20 00:00:00

abstract：:We have investigated the intramembranal ion traffic in apoptotic 3T6 cells in culture. Apoptosis was induced by various treatments, such as serum deprivation, high density growth and hydrogen peroxide at subnecrotic doses. Cell death was assessed by nucleosomal DNA fragmentation, single cell electrophoresis, immunoflu...

journal_title：Bioscience reports

authors： Bonincontro A,Iacoangeli A,Melucci-Vigo G,Risuleo G

更新日期：1997-12-01 00:00:00

abstract：:Conflicting opinions were recently expressed concerning the possible effect of alpha 2-adrenergic agonists upon cyclic AMP production in pancreatic islets. In the present study, clonidine inhibited glucose-induced insulin release from rat pancreatic islets, this inhibitory effect being abolished by idazoxan. Clonidine...

journal_title：Bioscience reports

authors： Garcia-Morales P,Dufrane SP,Sener A,Valverde I,Malaisse WJ

更新日期：1984-06-01 00:00:00

abstract：:NMR is ideal for characterizing non-enzymatic protein glycation, including AGEs (advanced glycation endproducts) underlying tissue pathologies in diabetes and ageing. Ribose, R5P (ribose-5-phosphate) and ADPR (ADP-ribose), could be significant and underinvestigated biological glycating agents especially in chronic inf...

journal_title：Bioscience reports

authors： Bullock PT,Reid DG,Ying Chow W,Lau WP,Duer MJ

更新日期：2014-04-01 00:00:00

abstract：:Cervical carcinoma is the most common gynecological cancer in women worldwide. Emerging evidence has shown that long non-coding RNAs (lncRNAs) participate in multiple biological processes of cervical carcinoma tumorigenesis. We aimed to investigate the function of a novel lncRNA RP11-284F21.9 in cervical carcinoma. We...

journal_title：Bioscience reports

authors： Han HF,Chen Q,Zhao WW

更新日期：2020-09-30 00:00:00

abstract：:Canstatin, the non-collagenous domain of collagen type IV α-chains, belongs to a series of collagen-derived angiogenic inhibitors. In this study, the inhibitory effect of recombinant canstatin on tumour growth was investigated using a gastric cancer xenograft model. The volume and weight of tumours in mice treated wit...

journal_title：Bioscience reports

authors： Xing YN,Deng P,Xu HM

更新日期：2014-04-01 00:00:00

abstract：:To observe the effect of gene expression and tumorigenicity in hybrid cells of human embryonic stem cells (hESCs) and ovarian cancer cells in vitro and in vivo using a mouse model, and to determine its feasibility in reprogramming tumour cells growth and apoptosis, for a potential exploration of the role of hESCs and ...

journal_title：Bioscience reports

authors： He K,Qu H,Xu LN,Gao J,Cheng FY,Xiang P,Zhou CQ

更新日期：2016-09-16 00:00:00

abstract：:Matrix-bound monoclonal antibodies against urokinase have been used to purify this enzyme by affinity chromatography. In a single-step procedure, urokinase can be isolated from crude preparations with high yield and high purity, and without loss of enzymatic activity. ...

journal_title：Bioscience reports

authors： Hérion P,Bollen A

更新日期：1983-04-01 00:00:00

abstract：:Bifunctional dihaem cytochrome c thiosulfate dehydrogenases/tetrathionate reductases (TsdA) exhibit different catalytic properties depending on the source organism. In the human food-borne intestinal pathogen Campylobacter jejuni, TsdA functions as a tetrathionate reductase enabling respiration with tetrathionate as a...

journal_title：Bioscience reports

authors： Kurth JM,Butt JN,Kelly DJ,Dahl C

更新日期：2016-12-09 00:00:00