Lytic effect of heparin on liposomes: possible mechanism of lysis of red blood cells by heparin.

Abstract:

:Heparin causes lysis of the multilamellar liposomes of all three charges, positive, neutral, and negative, and thus releases the entrapped [3H]glucose or chromate. The lytic effect of heparin is also observed in liposomes prepared from the lipids extracted from human red blood cells. Heparin is found to interact with the phospholipid bilayers, which suggests that the reported lytic effect of heparin on the red blood cells may be mediated through the membrane phospholipid components of these cells.

journal_name

Biosci Rep

journal_title

Bioscience reports

authors

Patel HM,Parvez N,Field J,Ryman BE

doi

10.1007/BF01121569

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

39-46

issue

1

eissn

0144-8463

issn

1573-4935

journal_volume

3

pub_type

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