Abstract:
:Developing physical models of complex dynamic systems showing emergent behaviour is key to informing on persistence and replication in biology, how living matter emerges from chemistry, and how to design systems with new properties. Herein we report a fully synthetic small molecule system in which a surfactant replicator is formed from two phase-separated reactants using an alkene metathesis catalyst. The replicator self-assembles into aggregates, which catalyse their own formation, and is thermodynamically unstable. Rather than replicating until the reactants are fully consumed, the metastable replicator is depleted in a second metathesis reaction, and closed system equilibrium is eventually reached. Mechanistic experiments suggest phase separation is responsible for both replicator formation and destruction.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Colomer I,Morrow SM,Fletcher SPdoi
10.1038/s41467-018-04670-2subject
Has Abstractpub_date
2018-06-08 00:00:00pages
2239issue
1issn
2041-1723pii
10.1038/s41467-018-04670-2journal_volume
9pub_type
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