Abstract：
:More than 20 years after the first outbreaks, the phylogenetic picture of PRRSV is still incomplete and full of gaps, especially in regards of PRRSV 1. Due to the exceptional diversity observed at the eastern borders of Europe and the low number of available sequences from Central Eastern European countries, the authors collected and analyzed both recent as well as already submitted sequences comparing them to a large backbone set of available ORF5 sequences representing the full spectrum of PRRSV 1 Subtype 1 diversity to conduct a systematic phylogenetic analysis and reclassification elucidating the diversity of the virus in these countries. Moreover, further analyses of the EUROSTAT data regarding the live pig movement trends revealed their influence of virus diversity and evolution. The results indicate that besides the effect of local, isolated divergent evolution and the use of modified live vaccines, the most important factor influencing a given country's virus diversity is the transboundary movement of live, infected animals.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Balka G,Podgórska K,Brar MS,Bálint Á,Cadar D,Celer V,Dénes L,Dirbakova Z,Jedryczko A,Márton L,Novosel D,Petrović T,Sirakov I,Szalay D,Toplak I,Leung FC,Stadejek Tdoi
10.1038/s41598-018-26036-wsubject
Has Abstractpub_date
2018-05-17 00:00:00pages
7811issue
1issn
2045-2322pii
10.1038/s41598-018-26036-wjournal_volume
8pub_type
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