Abstract:
:Human and animal infections of Enterocytozoon bieneusi (E. bieneusi) have consistently been reported worldwide, garnering public attention; however, the molecular epidemiology of E. bieneusi in the giant panda remains limited. We surveyed captive giant pandas in China for the presence of E. bieneusi by using PCR and sequence analysis of the ribosomal internal transcribed spacer (ITS) revealing a 34.5% positive rate, with seven known genotypes (SC02, EpbC, CHB1, SC01, D, F, and Peru 6) and five novel genotypes (SC04, SC05, SC06, SC07, and SC08) identified. We similarly analyzed water samples, and E. bieneusi was detected in two samples, with genotype SC02 identified. Phylogenetic analysis revealed that CHB1 did not cluster with any recognized group, while the remaining genotypes belonged to group 1. The predominance of zoonotic group 1 genotypes indicates a public health threat that giant pandas could spread E. bieneusi to humans. The identification of E. bieneusi in water samples suggests giant pandas could contribute to water contamination. Effective control measures are therefore needed to minimize the contamination of the water and prevent a human microsporidiosis outbreak.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Li W,Zhong Z,Song Y,Gong C,Deng L,Cao Y,Zhou Z,Cao X,Tian Y,Li H,Feng F,Zhang Y,Wang C,Li C,Yang H,Huang X,Fu H,Geng Y,Ren Z,Wu K,Peng Gdoi
10.1038/s41598-018-25096-2subject
Has Abstractpub_date
2018-04-26 00:00:00pages
6590issue
1issn
2045-2322pii
10.1038/s41598-018-25096-2journal_volume
8pub_type
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