A comparison study of radiation effective dose in ECG-Gated Coronary CT Angiography and calcium scoring examinations performed with a dual-source CT scanner.

abstract：:Pregnane X receptor (PXR) regulates glucose and lipid metabolism, but little is known of the nutritional regulation of PXR function. We investigated the genome wide effects of the nutritional status on the PXR mediated gene regulation in the liver. Mice were treated with a PXR ligand pregnenolone 16α-carbonitrile (PCN...

journal_title：Scientific reports

authors： Hassani-Nezhad-Gashti F,Kummu O,Karpale M,Rysä J,Hakkola J

更新日期：2019-11-13 00:00:00

abstract：:Historically, the environment has been viewed as a passive deposit of antimicrobial resistance mechanisms, where bacteria show biological cost for maintenance of these genes. Thus, in the absence of antimicrobial pressure, it is expected that they disappear from environmental bacterial communities. To test this scenar...

journal_title：Scientific reports

authors： Chamosa LS,Álvarez VE,Nardelli M,Quiroga MP,Cassini MH,Centrón D

更新日期：2017-03-31 00:00:00

abstract：:When coming to identify new 2D materials, our intuition would suggest us to look from layered instead of 3D materials. However, since graphite can be hypothetically derived from diamond by stretching it along its [111] axis, many 3D materials can also potentially be explored as new candidates for 2D materials. Using a...

journal_title：Scientific reports

authors： Wang J,Zhang Y

更新日期：2016-04-19 00:00:00

abstract：:In lung cancer a deregulation of Transforming Growth Factor-β (TGFβ) signaling has been observed. Yet, the impact of TGFβ in squamous cell carcinoma of the lung (LUSC) remained to be determined. We combined phenotypic and transcriptome-wide studies and showed that the stimulation of the LUSC cell line SK-MES1 with TGF...

journal_title：Scientific reports

authors： Dvornikov D,Schneider MA,Ohse S,Szczygieł M,Titkova I,Rosenblatt M,Muley T,Warth A,Herth FJ,Dienemann H,Thomas M,Timmer J,Schilling M,Busch H,Boerries M,Meister M,Klingmüller U

更新日期：2018-06-22 00:00:00

abstract：:The Paraná delta, growing at a rate of c. 2 km(2) yr(-1) since 6,000 yrs, is one of the most complete records of the Late Holocene in southern South America. The evolution of this 17,400 km(2) delta enclosed in Plata estuary, can be tracked by a series of 343 successive coastal-ridges showing a c.11 years period, in c...

journal_title：Scientific reports

authors： Milana JP,Kröhling D

更新日期：2015-08-06 00:00:00

abstract：:Previous studies of protein fold space suggest that fold coverage is plateauing. However, sequence sampling has been -and remains to a large extent- heavily biased, focusing on culturable phyla. Sustained technological developments have fuelled the advent of metagenomics and single-cell sequencing, which might correct...

journal_title：Scientific reports

authors： Barry Roche D,Brüls T

更新日期：2015-10-05 00:00:00

abstract：:To understand the ecosystem dynamics that underpin the year-round presence of a large generalist consumer, the Bryde's whale (Balaenoptera edeni brydei), we use a DNA metabarcoding approach and systematic zooplankton surveys to investigate seasonal and regional changes in zooplankton communities and if whale diet refl...

journal_title：Scientific reports

authors： Carroll EL,Gallego R,Sewell MA,Zeldis J,Ranjard L,Ross HA,Tooman LK,O'Rorke R,Newcomb RD,Constantine R

更新日期：2019-01-22 00:00:00

abstract：:Human mesenchymal stem cells (hMSCs) are widely used in regenerative medicine. In some applications, they must survive under low nutrient conditions engendered by avascularity. Strategies to improve hMSCs survival may be of high relevance in tissue engineering. Carnitine palmitoyltransferase 1 C (CPT1C) is a pseudoenz...

journal_title：Scientific reports

authors： Roa-Mansergas X,Fadó R,Atari M,Mir JF,Muley H,Serra D,Casals N

更新日期：2018-05-03 00:00:00

abstract：:Rice black-streaked dwarf disease, caused by rice black-streaked dwarf virus (RBSDV), is transmitted by small brown planthoppers (Laodelphax striatellus Fallén, SBPH) and causes severe yield loss in epidemic years in China and other East Asian countries. Breeding for resistance to RBSDV is a promising strategy to cont...

journal_title：Scientific reports

authors： Zhou T,Du L,Wang L,Wang Y,Gao C,Lan Y,Sun F,Fan Y,Wang G,Zhou Y

更新日期：2015-07-22 00:00:00

abstract：:Severe sepsis and septic shock are life-threatening conditions, with Gram-negative organisms responsible for most sepsis mortality. Systemic administration of compounds that block the action of lipopolysaccharide (LPS), a constituent of the Gram-negative outer cell membrane, is hampered by their hydrophobicity and cat...

journal_title：Scientific reports

authors： Cho EJ,Doh KO,Park J,Hyun H,Wilson EM,Snyder PW,Tsifansky MD,Yeo Y

更新日期：2016-07-14 00:00:00

abstract：:Although stenting of non-branched arterial segments has acceptable clinical outcomes, in-stent restenosis (ISR) and stent thrombosis remain clinically significant issues for vascular bifurcations (15-28% restenosis). Local fluid and solid stresses appear to play an important role in restenosis and thrombosis. The comb...

journal_title：Scientific reports

authors： Chen HY,Chatzizisis YS,Louvard Y,Kassab GS

更新日期：2020-06-15 00:00:00

abstract：:Understanding the transmission patterns of African swine fever (ASF) among wild boar (Sus scrofa) is an issue of major interest, especially in the wake of the current ASF epidemic. Given the high stability of ASF-virus, there is concern about scavengers spreading infectious carcass material in the environment. Here, w...

journal_title：Scientific reports

authors： Probst C,Gethmann J,Amler S,Globig A,Knoll B,Conraths FJ

更新日期：2019-08-07 00:00:00

abstract：:Parasites and pathogens of the honey bee (Apis mellifera) are key factors underlying colony losses, which are threatening the beekeeping industry and agriculture as a whole. To control the spread and development of pathogen infections within the colony, honey bees use plant resins with antibiotic activity, but little ...

journal_title：Scientific reports

authors： Annoscia D,Zanni V,Galbraith D,Quirici A,Grozinger C,Bortolomeazzi R,Nazzi F

更新日期：2017-07-24 00:00:00

abstract：:This study focused on the mechanisms that fatty acid conjugating strains - Bifidobacterium breve NCIMB 702258 and Bifidobacterium breve DPC 6330 - influence lipid metabolism when ingested with α-linolenic acid (ALA) enriched diet. Four groups of BALB/c mice received ALA enriched diet (3% (w/w)) either alone or in comb...

journal_title：Scientific reports

authors： Patterson E,Wall R,Lisai S,Ross RP,Dinan TG,Cryan JF,Fitzgerald GF,Banni S,Quigley EM,Shanahan F,Stanton C

更新日期：2017-03-07 00:00:00

abstract：:Dysfunction or death of retinal pigment epithelial (RPE) cells is involved in some forms of Retinitis Pigmentosa and in age-related macular degeneration (AMD). Since there is no cure for most patients affected by these diseases, the transplantation of RPE cells derived from human pluripotent stem cells (hPSCs) represe...

journal_title：Scientific reports

authors： Regent F,Morizur L,Lesueur L,Habeler W,Plancheron A,Ben M'Barek K,Monville C

更新日期：2019-07-23 00:00:00

abstract：:Fibroblast growth factor (FGF) 23 is a phosphaturic hormone that directly targets cardiac myocytes via FGF receptor (FGFR) 4 thereby inducing hypertrophic myocyte growth and the development of left ventricular hypertrophy (LVH) in rodents. Serum FGF23 levels are highly elevated in patients with chronic kidney disease ...

journal_title：Scientific reports

authors： Grabner A,Schramm K,Silswal N,Hendrix M,Yanucil C,Czaya B,Singh S,Wolf M,Hermann S,Stypmann J,Di Marco GS,Brand M,Wacker MJ,Faul C

更新日期：2017-05-16 00:00:00

abstract：:Pyrophosphate (PPi) is produced by anabolic reactions and serves as an energy donor in the cytosol of plant cells; however, its accumulation to toxic levels disrupts several common biosynthetic pathways and is lethal. Before acquiring photosynthetic capacity, young seedlings must endure a short but critical heterotrop...

journal_title：Scientific reports

authors： Ferjani A,Kawade K,Asaoka M,Oikawa A,Okada T,Mochizuki A,Maeshima M,Hirai MY,Saito K,Tsukaya H

更新日期：2018-10-02 00:00:00

abstract：:Human CD4+ T cells play an important role in the immune response to Mycobacterium tuberculosis (MTB). However, little is known about the spectratyping characteristics of the CD4+ T-cell receptor (TCR) α- and β-chains CDR3 region in tuberculosis (TB) patients. We sorted MTB peptide E7-bound CD4+ T cells by using E7/HLA...

journal_title：Scientific reports

authors： Gan Y,Wang C,Fang Y,Yao Y,Tu X,Wang J,Huang X,Tan Y,Chen T,Zhang K,Shen Y,Zhou L,Liu J,Lai X

更新日期：2018-07-02 00:00:00

abstract：:Although guidelines recommend BRCA testing for all women with non-mucinous epithelial ovarian cancer, there is significant variability in access to testing across the UK. A germline BRCA mutation (BRCAm) in ovarian cancer patients provides prognostic and predictive information and influences clinical management, such ...

journal_title：Scientific reports

authors： Rumford M,Lythgoe M,McNeish I,Gabra H,Tookman L,Rahman N,George A,Krell J

更新日期：2020-02-25 00:00:00

abstract：:Wetting failure is of vital importance to many physical phenomena, such as industrial coating and drop emission. Here we show when and how the surface roughness promotes the destabilization of a moving contact line on a hydrophilic surface. Beyond the balance of the driving force and viscous resistance where a stable ...

journal_title：Scientific reports

authors： Zhao MH,Chen XP,Wang Q

更新日期：2014-06-20 00:00:00

abstract：:Planktonic foraminifera (PF) life cycles are highly sensitive to marine conditions, which are evolving rapidly due to anthropogenic climate change. Even though PF shells in the sedimentary record serve as prominent proxies of past ocean conditions, very little is still known about their life cycles, particularly in ol...

journal_title：Scientific reports

authors： Chernihovsky N,Almogi-Labin A,Kienast SS,Torfstein A

更新日期：2020-10-15 00:00:00

abstract：:Currently, blueberry bruising is evaluated by either human visual/tactile inspection or firmness measurement instruments. These methods are destructive, time-consuming, and subjective. The goal of this paper was to develop a non-destructive approach for blueberry bruising detection and quantification. Experiments were...

journal_title：Scientific reports

authors： Jiang Y,Li C,Takeda F

更新日期：2016-10-21 00:00:00

abstract：:To investigate the changes and clinical significance of brain structural abnormalities in patients with Meige syndrome and related depressive symptoms. We retrospectively analysed clinical data, imaging examinations, and Hamilton Depression Rating scale scores in 46 patients with Meige syndrome from January 2017 to Ja...

journal_title：Scientific reports

authors： Liu J,Li L,Chen L,Liu R,Jiang Y,Fang J,Wang D,Liu Z,Ouyang J

更新日期：2020-09-03 00:00:00

abstract：:The objective of our in vivo study was to compare the effects of the osteotomy on the thermal alterations, the bone healing and count of polymorphonuclear cells, comparing the drill design (cylindrical or conical) using continuous or intermittent movement. Twelve rabbits were used, which were made four osteotomies (n ...

journal_title：Scientific reports

authors： Gehrke SA,Treichel TLE,Aramburú Júnior J,de Aza PN,Prados-Frutos JC

更新日期：2020-11-26 00:00:00

abstract：:Recently, CuZr-based bulk metallic glass (BMG) composites reinforced by the TRIP (transformation-induced plasticity) effect have been explored in attempt to accomplish an optimal of trade-off between strength and ductility. However, the design of such BMG composites with advanced mechanical properties still remains a ...

journal_title：Scientific reports

authors： Qin YS,Han XL,Song KK,Tian YH,Peng CX,Wang L,Sun BA,Wang G,Kaban I,Eckert J

更新日期：2017-02-13 00:00:00

abstract：:The ability to respond appropriately to challenges is an important contributor to fitness. Variation in the regulation of glucocorticoid hormones, which mediate the phenotypic response to challenges, can therefore influence the ability to persist in a given environment. We compared stress responsiveness in four popula...

journal_title：Scientific reports

authors： Zimmer C,Taff CC,Ardia DR,Rose AP,Aborn DA,Johnson LS,Vitousek MN

更新日期：2020-08-13 00:00:00

abstract：:We study theoretically and numerically the kinetics of the coefficient of friction of an elastomer due to abrupt changes of sliding velocity. Numerical simulations reveal the same qualitative behavior which has been observed experimentally on different classes of materials: the coefficient of friction first jumps and ...

journal_title：Scientific reports

authors： Li Q,Dimaki A,Popov M,Psakhie SG,Popov VL

更新日期：2014-07-28 00:00:00

abstract：:We show that through the wave energy conserved and reversible process of coherent interactions of scalar waves in a multi-channel system joint by a common junction, it is possible to generate outgoing waves only in certain channels by controlling the incoming waves. We refer to such processes as coherent perfect chann...

journal_title：Scientific reports

authors： Zhang X,Meng C,Yang Z

更新日期：2017-10-24 00:00:00

abstract：:Crystalline materials exhibit long-range ordered lattice unit, within which resides nonperiodic structural features called defects. These crystallographic defects play a vital role in determining the physical and mechanical properties of a wide range of material systems. While computer vision has demonstrated success ...

journal_title：Scientific reports

authors： Roberts G,Haile SY,Sainju R,Edwards DJ,Hutchinson B,Zhu Y

更新日期：2019-09-04 00:00:00

abstract：:Here we report two types of defect-induced photoluminescence (PL) blinking behaviors observed in single epitaxial InGaAs quantum dots (QDs). In the first type of PL blinking, the "off" period is caused by the trapping of hot electrons from the higher-lying excited state (absorption state) to the defect site so that it...

journal_title：Scientific reports

authors： Hu F,Cao Z,Zhang C,Wang X,Xiao M

更新日期：2015-03-10 00:00:00