Abstract：
ABSTARCT:This work explores a new class of vortex/magnetite/iron oxide nanoparticles designed for magnetic hyperthermia applications. These nanoparticles, named Vortex Iron oxide Particles (VIPs), are an alternative to the traditional Superparamagnetic Iron Oxide Nanoparticles (SPIONs), since VIPs present superior heating power while fulfilling the main requirements for biomedical applications (low cytotoxicity and nonremanent state). In addition, the present work demonstrates that the synthesized VIPs also promote an internalization and aggregation of the particles inside the cell, resulting in a highly localized hyperthermia in the presence of an alternating magnetic field. Thereby, we demonstrate a new and efficient magnetic hyperthermia strategy in which a small, but well localized, concentration of VIPs can promote an intracellular hyperthermia process.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Dias CSB,Hanchuk TDM,Wender H,Shigeyosi WT,Kobarg J,Rossi AL,Tanaka MN,Cardoso MB,Garcia Fdoi
10.1038/s41598-017-14633-0subject
Has Abstractpub_date
2017-11-01 00:00:00pages
14843issue
1issn
2045-2322pii
10.1038/s41598-017-14633-0journal_volume
7pub_type
杂志文章abstract：:The aim of this study was to identify novel plasma metabolic signatures with possible relevance during multiple myeloma (MM) development and progression. A biochemical quantitative phenotyping platform based on targeted electrospray ionization tandem mass spectrometry technology was used to aid in the identification o...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-75862-4
更新日期：2020-12-14 00:00:00
abstract：:Novel-morphological Fe3O4 nanosheets with magnetochromatic property have been prepared by a modified solvothermal method. Such nanosheets could form one-dimension photonic crystal under an external magnetic field. The Fe3O4 nanosheets suspension could strongly diffract visible light and display varied colors with chan...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep09320
更新日期：2015-03-23 00:00:00
abstract：:Most tropical evergreen rain forests are characterised by varying degrees of precipitation seasonality that influence plant phenology and litterfall dynamics. Soil microbes are sensitive to soil water:air ratio and to nutrient availability. We studied if within-year seasonality in precipitation and litterfall-derived ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-22380-z
更新日期：2018-03-12 00:00:00
abstract：:Anti-PD1 immunotherapy has emerged as a gold-standard treatment for first- or second-line treatment of stage IV NSCLC, with response rates ranging from 10 to 60%. Strategies to improve the disease control rate are needed. Several reports suggested that debulking surgery enhances anti-tumor immunity. We aimed at examin...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-52913-z
更新日期：2019-11-15 00:00:00
abstract：:Peri-implant disease is a chronic inflammation of the soft and hard tissues around a dental implant, resulting from bacterial infection. Recent evidence indicates that some pro-inflammatory cytokines and chemokines released by immunocytes are substantially responsible for the progress and consequence of inflammation. ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-06937-y
更新日期：2017-08-01 00:00:00
abstract：:The regional and international trade of live animals facilitates the movement, spillover, and emergence of zoonotic and epizootic pathogens around the world. Detecting pathogens in trade is critical for preventing their continued movement and introduction, but screening a sufficient fraction to ensure rare infections ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-66280-7
更新日期：2020-06-24 00:00:00
abstract：:Hepatocarcinoma (HCC) is one of the deadliest cancers in the world and represents a significant disease burden. Better biomarkers are needed for early detection of HCC. Metabolomics was applied to urine samples obtained from HCC patients to discover noninvasive and reliable biomarkers for rapid diagnosis of HCC. Metab...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19763
更新日期：2016-01-25 00:00:00
abstract：:Patients with liver cirrhosis are susceptible to infections with high short-term mortalities. One CD97-related EGF-TM7 molecule, EMR2 (EGF-like molecule containing mucin-like hormone receptor 2), had been shown to regulate human neutrophil function, potentiate systemic inflammation. Nevertheless, EMR2 could also suppr...
journal_title：Scientific reports
pub_type： 临床试验,杂志文章
doi：10.1038/srep38250
更新日期：2016-12-01 00:00:00
abstract：:Topological objects of nontrivial spin or dipolar field textures, such as skyrmions, merons, and vortices, interacting with applied external fields in ferroic materials are of great scientific interest as an intriguing playground of unique physical phenomena and novel technological paradigms. The quest for new topolog...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35199
更新日期：2016-10-07 00:00:00
abstract：:Perturbations in lipid metabolic pathways to meet the bioenergetic and biosynthetic requirements is a principal characteristic of cancer cells. Sphingolipids (SPLs) are the largest class of bioactive lipids associated to various aspects of tumorigenesis and have been extensively studied in cancer cell lines and experi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-61283-w
更新日期：2020-03-13 00:00:00
abstract：:High-performance ZnO-Pr6O11 thin-film varistors were fabricated simply by hot-dipping oxygen-deficient zinc oxide thin films in Pr6O11 powder. The films had a composition of ZnO0.81 and a thickness of about 200 nm, which were deposited by radio frequency magnetron sputtering a sintered zinc oxide ceramic target. Speci...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep41994
更新日期：2017-02-03 00:00:00
abstract：:Ambient seismic noise is characterized by randomness incurred by the random position and strength of the noise sources as well as the heterogeneous properties of the medium through which it propagates. Here we use ambient noise data recorded prior to the 1996 Gjálp eruption in Iceland in order to show that a reduction...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep37733
更新日期：2016-11-24 00:00:00
abstract：:Atmospheric-pressure N2, He, air, and O2 microplasma arrays have been used to investigate the effects of plasma treatment on seed germination and seedling growth of mung bean in aqueous solution. Seed germination and growth of mung bean were found to strongly depend on the feed gases used to generate plasma and plasma...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep32603
更新日期：2016-09-01 00:00:00
abstract：:Severe sepsis and septic shock are life-threatening conditions, with Gram-negative organisms responsible for most sepsis mortality. Systemic administration of compounds that block the action of lipopolysaccharide (LPS), a constituent of the Gram-negative outer cell membrane, is hampered by their hydrophobicity and cat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep29739
更新日期：2016-07-14 00:00:00
abstract：:The microwave emitting Radio Electric Asymmetric Conveyor (REAC) is a technology able to interact with biological tissues at low emission intensity (2 mW at the emitter and 2.4 or 5.8 GHz) by inducing radiofrequency generated microcurrents. It shows remarkable biological effects at many scales from gene modulations up...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep18200
更新日期：2015-12-11 00:00:00
abstract：:The study of the preparation phase of large earthquakes is essential to understand the physical processes involved, and potentially useful also to develop a future reliable short-term warning system. Here we analyse electron density and magnetic field data measured by Swarm three-satellite constellation for 4.7 years,...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56599-1
更新日期：2019-12-30 00:00:00
abstract：:Childhood obesity is a risk factor for asthma, but the molecular mechanisms linking both remain elusive. Since obesity leads to chronic low-grade inflammation and affects metabolic signaling we hypothesized that postnatal hyperalimentation (pHA) induced by maternal high-fat-diet during lactation leads to early-onset o...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24168
更新日期：2016-04-18 00:00:00
abstract：:Secondary visual loss occurs in millions of patients due to a wound-healing response, known as posterior capsule opacification (PCO), following cataract surgery. An intraocular lens (IOL) is implanted into residual lens tissue, known as the capsular bag, following cataract removal. Standard IOLs allow the anterior and...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24453
更新日期：2016-04-14 00:00:00
abstract：:Photosynthetic activity is indispensable for plant growth and survival and it depends on the synthesis of plastidial isoprenoids as chlorophylls and carotenoids. In the non-mevalonate pathway (MEP), the 1-deoxy-D-xylulose-5-phosphate synthase 1 (DXS1) enzyme has been postulated to catalyze the rate-limiting step in th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45333
更新日期：2017-03-28 00:00:00
abstract：:The peptidyl nucleoside blasticidin S (BS) isolated from Streptomyces griseochromogenes was the first non-mercurial fungicide used on a large scale to prevent rice blast. In the biosynthesis of BS, leucylblasticidin S (LBS) was suggested as the penultimate metabolite with 20-fold less inhibitory activity than the fina...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep17641
更新日期：2015-12-01 00:00:00
abstract：:We present the synthesis of new composite materials based on copper nanoparticles (Cu NPs) deposited onto montmorillonite (MK10) and quartz sand, for degradation of atrazine, in the context of an advanced oxidation process (AOP). The synthesis involves a first step in which polyethylenimine (PEI) capped Cu NPs (PEI_Cu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-01429-5
更新日期：2017-05-03 00:00:00
abstract：:Passive immunotherapy may have particular benefits for the treatment of severe influenza infection in at-risk populations, however little is known of the impact of passive immunotherapy on the formation of memory responses to the virus. Ideally, passive immunotherapy should attenuate the severity of infection while st...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep29154
更新日期：2016-07-06 00:00:00
abstract：:The dispersal of animals from their birth place has profound effects on the immediate survival and longer-term persistence of populations. Molecular studies have estimated that bumblebee colonies can be established many kilometers from their queens' natal nest site. However, little is known about when and how queens d...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-40355-6
更新日期：2019-03-20 00:00:00
abstract：:According to the Source Monitoring Framework, the origin of a memory is remembered through the retrieval of specific features (e.g. perceptive, sensitive, affective signals). In two source discrimination tasks, we studied the ability of cuttlefish to remember the modality in which an item had been presented several ho...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-62335-x
更新日期：2020-03-25 00:00:00
abstract：:Our study focused on quantifying the alterations of streamflow at a weir site due to the construction of a mini-hydropower plant in the Gurugoda Oya (Sri Lanka), and evaluating the spatial responses of benthic macroinvertebrates to altered flow regime. The HEC-HMS 3.5 model was applied to the Gurugoda Oya sub-catchmen...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-79576-5
更新日期：2021-01-12 00:00:00
abstract：:The elastic responsiveness of single cellulose nanofibres is important for advanced analysis of biological tissues and their use in sophisticated functional materials. However, the mechanical responsiveness derived from the twisted structure of cellulose nanofibres (CNFs) has remained unexplored. In this study, finite...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80890-1
更新日期：2021-01-12 00:00:00
abstract：:CD26 displays variable levels between effector (TH17 ≫ TH1 > TH2 > Treg) and naïve/memory (memory > naïve) CD4+ T lymphocytes. Besides, IL-6/IL-6R is associated with TH17-differentiation and asthma severity. Allergic/atopic asthma (AA) is dominated by TH2 responses, while TH17 immunity might either modulate the TH2-de...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-43622-8
更新日期：2019-05-17 00:00:00
abstract：:The objective of the study was to estimate if altered levels of alpha-synuclein can be detected in tear fluid of patients with Parkinson's disease (PD). Therefore, tear fluid samples of 75 PD patients, 75 control subjects and 31 atypical Parkinsonian patients were collected and analyzed in triplicates using an ultra-s...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-65503-1
更新日期：2020-05-22 00:00:00
abstract：:Vermetids form reefs in sub-tropical and warm-temperate waters that protect coasts from erosion, regulate sediment transport and accumulation, serve as carbon sinks and provide habitat for other species. The gastropods that form these reefs brood encapsulated larvae; they are threatened by rapid environmental changes ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep04189
更新日期：2014-02-28 00:00:00
abstract：:Leishmaniasis is a Neglected Tropical Disease caused by the insect-vector borne protozoan parasite, Leishmania species. Infection affects millions of the world's poorest, however vaccines are absent and drug therapy limited. Recently, public-private partnerships have developed to identify new modes of controlling leis...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-22063-9
更新日期：2018-03-02 00:00:00
