Abstract：
:Potential benefits of carbohydrate counting for glycemic control in patients with type 1 diabetes mellitus (T1DM) remain inconclusive. Our aim is to systematically assess the efficacy of carbohydrate counting in patients with T1DM. We searched PubMed, Embase, Web of Science, Cochrane Library and the Chinese Biology Medicine (CBM) up to December 2015. Randomized controlled trials (RCTs) with at least 3 months follow-up that evaluated carbohydrate counting compared with usual or other diabetes dietary education in patients with T1DM were included. Overall meta-analysis identified a significant decrease in HbA1c concentration with carbohydrate counting versus other diabetes diet method or usual diabetes dietary education (SMD: -0.35, 95%CI: -0.65 to -0.05, P = 0.023). Subgroup analysis restricted to trials which compared carbohydrate counting with usual diabetes dietary found a significant decrease in HbA1c in carbohydrate counting group (SMD: -0.68, 95%CI: -0.98 to -0.38, P = 0.000), and a similar result has emerged from six studies in adults (SMD: -0.40, 95%CI: -0.78 to -0.02, P = 0.037). Carbohydrate counting may confer positive impact on glucose control. Larger clinical trials are warranted to validate this positive impact.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Fu S,Li L,Deng S,Zan L,Liu Zdoi
10.1038/srep37067subject
Has Abstractpub_date
2016-11-14 00:00:00pages
37067issn
2045-2322pii
srep37067journal_volume
6pub_type
杂志文章,meta分析,评审abstract：:As part of an ongoing study of new insulin mimetic agents from medicinal plants, the 70% EtOH extract of Symplocos cochinchinensis was found to have a stimulatory effect on glucose uptake in 3T3-L1 adipocyte cells. The intensive targeted isolation of this active extract resulted in ten new hydroxyoleoside-type compoun...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-38013-4
更新日期：2019-02-19 00:00:00
abstract：:Glial cells actively maintain the homeostasis of brain parenchyma, regulating neuronal excitability and preserving the physiological composition of the extracellular milieu. Under pathological conditions, some functions of glial cells could be compromised, exacerbating the neurotoxic processes. We investigated if the ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-25940-5
更新日期：2018-05-16 00:00:00
abstract：:The pentameric serum IgMs are critical to immune defense and surveillance through cytotoxicity against microbes and nascent cancer cells. Ficolins, a group of oligomeric lectins with an overall structure similar to C1q and mannose-binding lectin (MBL) participate in microbe infection and apoptotic cell clearance by ac...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep07824
更新日期：2015-01-16 00:00:00
abstract：:Sphingobium sp. strain TCM1 can degrade tris(2-chloroethyl) phosphate (TCEP) to inorganic phosphate and 2-chloroethanol. A phosphotriesterase (PTE), phosphodiesterase (PDE) and phosphomonoesterase (PME) are believed to be involved in the degradation of TCEP. The PTE and PME that respectively catalyze the first and thi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-03142-9
更新日期：2017-06-06 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-64132-y
更新日期：2020-04-28 00:00:00
abstract：:The application of CLSI and EUCAST guidelines led to many discrepancies. Various doubts have already appeared in preliminary stages of microbiological diagnostics of Haemophilus spp. A total of 87 H. parainfluenzae isolates were obtained from throat or nasopharyngeal swabs from adults 18 to 70 years old, both healthy ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-68161-5
更新日期：2020-07-13 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19902
更新日期：2016-01-27 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-79356-1
更新日期：2021-01-14 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-41182-5
更新日期：2019-03-18 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep20339
更新日期：2016-02-02 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-19495-8
更新日期：2018-01-22 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-68260-3
更新日期：2020-07-24 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-53926-4
更新日期：2019-11-20 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-47290-6
更新日期：2019-07-30 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35230-9
更新日期：2018-11-20 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-50501-9
更新日期：2019-10-01 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-27602-y
更新日期：2018-07-06 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01039
更新日期：2013-01-01 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2020-02-25 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-71388-x
更新日期：2020-08-31 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-05739-6
更新日期：2017-07-14 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章,meta分析
doi：10.1038/srep06107
更新日期：2014-08-22 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-03644-6
更新日期：2017-06-13 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-77583-0
更新日期：2020-11-26 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-44278-0
更新日期：2019-05-27 00:00:00
abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-019-44071-z
更新日期：2019-06-05 00:00:00
abstract：:Coupled networks are extremely fragile because a node failure of a network would trigger a cascade of failures on the entire system. Existing studies mainly focused on the cascading failures and the robustness of coupled networks when the networks suffer from attacks. In reality, it is necessary to recover the damaged...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep08439
更新日期：2015-02-13 00:00:00
abstract：:1-Aminocyclopropane-1-carboxylic acid (ACC) is a precursor molecule of ethylene whose concentration is elevated in the plant subjected to biotic and abiotic stress. Several soil microorganisms are reported to produce ACC deaminase (ACCd) which degrades ACC thereby reducing stress ethylene in host plants. This study is...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35565-3
更新日期：2018-11-30 00:00:00
abstract：:Alzheimer's disease (AD), an irreversible progressive neurodegenerative disease, causes characteristic cognitive impairment, and no curative treatments are currently available. Stem cell transplantation offers a powerful tool for the treatment of AD. We conducted a systematic review and meta-analysis of data from cont...
journal_title：Scientific reports
pub_type： 杂志文章,meta分析,评审
doi：10.1038/srep12134
更新日期：2015-07-10 00:00:00
abstract：:An important number of healthy and diseased tissues shows spatial variations in their metabolic capacities across the tissue. The liver is a prime example of such heterogeneity where the gradual changes in various metabolic activities across the liver sinusoid is termed as "zonation" of the liver. Here, we introduce t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-27179-6
更新日期：2018-06-12 00:00:00
