Abstract：
:Recently, detecting biological particles by analyzing their mechanical properties has attracted increasing attention. To detect and identify different bioparticles and estimate their dimensions, a mechanical nanosensor is introduced in this paper. To attract particles, numerous parts of the substrate are coated with different chemicals as probe detectors or receptors. The principal of cell recognition in this sensor is based on applying an electrical excitation and measuring the maximum deflection of the actuated cantilever electrode. Investigating the critical voltage that causes pull-in instability is also important in such highly-sensitive detectors. The governing equation of motion is derived from Hamilton's principle. A Galerkin approximation is applied to discretize the nonlinear equation, which is solved numerically. Accuracy of the proposed model is validated by comparison studies with available experimental and theoretical data. The coupled effects of geometrical and mechanical properties are included in this model and studied in detail. Moreover, system identification is carried out to distinguish bioparticles by a stability analysis. Due to the absence of a similar concept and device, this research is expected to advance the state-of-the-art biosystems in identifying particles.
journal_name
Sci Repjournal_title
Scientific reportsauthors
SoltanRezaee M,Bodaghi Mdoi
10.1038/s41598-020-60296-9subject
Has Abstractpub_date
2020-02-25 00:00:00pages
3385issue
1issn
2045-2322pii
10.1038/s41598-020-60296-9journal_volume
10pub_type
杂志文章abstract：:Analyzing the cytotoxic functions of effector cells, such as NK cells against target cancer cells, is thought to be necessary for predicting the clinical efficacy of antibody-dependent cellular cytotoxicity (ADCC) -dependent antibody therapy. The (51)Cr release assay has long been the most widely used method for quant...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19772
更新日期：2016-01-27 00:00:00
abstract：:A novel approach of chemical mechanical polishing (CMP) is developed for cadmium zinc telluride (CdZnTe or CZT) wafers. The approach uses environment-friendly slurry that consists of mainly silica, hydrogen peroxide, and citric acid. This is different from the previously reported slurries that are usually composed of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep26891
更新日期：2016-05-26 00:00:00
abstract：:We study the local indistinguishability problem of quantum states. By introducing an easily calculated quantity, non-commutativity, we present an criterion which is both necessary and sufficient for the local indistinguishability of a complete set of pure orthogonal product states. A constructive distinguishing proced...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep06336
更新日期：2014-09-11 00:00:00
abstract：:The 3D MHD nonlinear radiative hybrid nanofluid flow across an irregular dimension sheet with slip effect is studied numerically. The hybrid nanofluid consists of copper oxide (CuO) and magnesium oxide (MgO) nanoparticles embedded in methanol or methyl alcohol (MA). The governing PDEs' are altered as ODEs' using simil...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-66102-w
更新日期：2020-06-08 00:00:00
abstract：:Harvesting light for optical torque is of significant importance, owing to its ability to rotate nano- or micro-objects. Nevertheless, applying a strong optical torque remains a challenging task: angular momentum must conserve but light is limited. A simple argument shows the tendency for two objects with strong mutua...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep27927
更新日期：2016-06-13 00:00:00
abstract：:miRNAs play an indispensable role in human carcinogenesis. Dysregulated miR-1180-3p has been observed in several types of cancer, including hepatocellular carcinoma (HCC). This study intends to correlate the expression level of miR-1180-3p with clinical features and overall survival in HCC patients. The expression and...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-68450-z
更新日期：2020-07-14 00:00:00
abstract：:Temperature-modulated space-charge-limited-current spectroscopy (TMSCLC) is applied to quantitatively evaluate the density of trap states in the band-gap with high energy resolution of semiconducting hybrid lead halide perovskite single crystals. Interestingly multicomponent deep trap states were observed in the pure ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-40139-y
更新日期：2019-03-04 00:00:00
abstract：:The use of electricity generated from clean and renewable sources, such as water, wind, or sunlight, requires efficiently distributed electrical energy storage by high-power and high-energy secondary batteries using abundant, low-cost materials in sustainable processes. American Science Policy Reports state that the n...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep14120
更新日期：2015-09-14 00:00:00
abstract：:This paper presents an ultracompact tunable device for power splitting and switching by tuning the Fermi energy level of monolayer patternless graphene underneath a slotted multimode interference (MMI) coupler operating in the mid-infrared, λ = 9-11 μm. By introducing a high-index silicon slot in the central region of...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-49186-x
更新日期：2019-09-04 00:00:00
abstract：:Macrophages play a crucial role in the control and elimination of invading Mycobacterium tuberculosis (Mtb), and also serve as the major residence for Mtb. However, the interaction between macrophages and Mtb remains to be clearly determined. Although long noncoding RNAs (lncRNAs) have emerged as key regulators in man...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep38963
更新日期：2016-12-14 00:00:00
abstract：:Wavelength, polarization and orbital angular momentum of light are important degrees of freedom for processing and encoding information in optical communication. Over the years, the generation and conversion of orbital angular momentum in nonlinear optical media has found many novel applications in the context of opti...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45424-4
更新日期：2019-06-19 00:00:00
abstract：:In this paper, a new strategy is reported for preparing a label-free β-trophin electrochemiluminescent (ECL) immunosensor with good specificity, reproducibility and stability. An aquagel polymer from the hydrolysis of (3-aminopropyl) trimethoxysilane acted as the linker to catch the Au nanoparticles (AuNPs) on the ind...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-11750-8
更新日期：2017-09-11 00:00:00
abstract：:Culture medium of mesenchymal stromal cells (MSCs) is usually supplemented with either human platelet lysate (HPL) or fetal calf serum (FCS). Many studies have demonstrated that proliferation and cellular morphology are affected by these supplements - it is therefore important to determine if they favor outgrowth of d...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-05207-1
更新日期：2017-07-11 00:00:00
abstract：:Many drugs commonly prescribed during pregnancy lack a fetal safety recommendation - called FDA 'category C' drugs. This study aims to classify these drugs into harmful and safe categories using knowledge gained from chemoinformatics (i.e., pharmacological similarity with drugs of known fetal effect) and empirical dat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-12943-x
更新日期：2017-10-09 00:00:00
abstract：:The physiological roles of the protease inhibitor SERPINB3 (SB3) are still largely unknown. The study was addressed to assess the biological effects of this serpin in vivo using a SB3 transgenic mouse model. Two colonies of mice (123 transgenic for SB3 and 148 C57BL/6J controls) have been studied. Transgenic (TG) mice...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep03056
更新日期：2013-10-28 00:00:00
abstract：:The GntR family transcription regulator HpaR1 identified from Xanthomonas campestris pv. campestris has been previously shown to positively regulate the genes responsible for hypersensitive reaction and pathogenicity and to autorepress its own expression. Here, we demonstrated that HpaR1 is a global regulator that pos...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19862
更新日期：2016-01-28 00:00:00
abstract：:The present study aimed to evaluate the accuracy and repeatability of morphological contour interpolation (MCI)-based semiautomatic segmentation method for volumetric measurements of bone grafts around dental implants. Three in vitro (one with a cylinder and two with a geometrically complex form) and four ex vivo mode...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-71651-1
更新日期：2020-09-10 00:00:00
abstract：:Environmental pollutants as non-heritable factors are now recognized as triggers for multiple human inflammatory diseases involving T cells. We postulated that lipid antigen presentation mediated by cluster of differentiation 1 (CD1) proteins for T cell activation is susceptible to lipophilic environmental pollutants....
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-02229-7
更新日期：2017-05-18 00:00:00
abstract：:Assessment of colonic motor dysfunction is rarely done because of inadequate methodology and lack of knowledge about normal motor patterns. Here we report on elucidation of intraluminal pressure patterns using High Resolution Colonic Manometry during a baseline period and in response to a meal, in 15 patients with con...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep41436
更新日期：2017-02-20 00:00:00
abstract：:We study the interaction between localized vibrational modes and propagating phonons in graphene nanoribbons with different types of localized internal and edge defects. We analyze discrete eigenmodes of the nanoribbons with defects and also employ direct numerical simulations of the ballistic phonon and heat transpor...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-04987-w
更新日期：2017-07-05 00:00:00
abstract：:Microstructures in nature are ultrafine and ordered in biological roles, which have attracted material scientists. Spirulina forms three-dimensional helical microstructure, one of remarkable features in nature beyond our current processing technology such as lithography in terms of mass-productivity and structural mul...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep04919
更新日期：2014-05-12 00:00:00
abstract：:There is a lack of evidence that either conventional observational rating scale or biomechanical system is a better tremor assessment tool. This work focuses on comparing a biomechanical system and the Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale in terms of test-retest ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-44142-1
更新日期：2019-05-31 00:00:00
abstract：:Change in body composition with skeletal muscle wasting, a major component of pulmonary cachexia, is associated with mortality in chronic obstructive pulmonary disease and cancer. However, its relevance in interstitial lung diseases (ILDs) remains unclear. We hypothesized changes in body composition would be associate...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-32478-z
更新日期：2018-09-19 00:00:00
abstract：:In recent years, conservation biologists have raised awareness about the risk of ecological interference between massively introduced managed honeybees and the native wild bee fauna in protected natural areas. In this study, we surveyed wild bees and quantified their nectar and pollen foraging success in a rosemary Me...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-27591-y
更新日期：2018-06-18 00:00:00
abstract：:In addition to its role in sister chromatid cohesion, genome stability and integrity, the cohesin complex is involved in gene transcription. Mutations in core cohesin subunits SMC1A, SMC3 and RAD21, or their regulators NIPBL and HDAC8, cause Cornelia de Lange syndrome (CdLS). Recent evidence reveals that gene expressi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16803
更新日期：2015-11-19 00:00:00
abstract：:Age of complementary foods introduction is associated with childhood anemia, but the ideal age for the introduction of complementary foods to infants is a continuing topic of debate. We examined the longitudinal association between complementary foods introduction age and risk of anemia in 18,446 children from the Jia...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep44726
更新日期：2017-03-23 00:00:00
abstract：:A prophage vB_CibM-P1 was induced by mitomycin C from the epipelagic strain Citromicrobium bathyomarinum JL354, a member of the alpha-IV subcluster of marine aerobic anoxygenic phototrophic bacteria (AAPB). The induced bacteriophage vB_CibM-P1 had Myoviridae-like morphology and polyhedral heads (approximately capsid 6...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep07118
更新日期：2014-11-19 00:00:00
abstract：:A two step excitation scheme in hot atomic sodium vapor is experimentally investigated. The observed effects reflect a coupling between the 32S, 32P and the 32D states. We present the relative dependence on detuning of the two utilized lasers around λ = 589 nm and 819 nm. Unlike expected, we achieve a higher detuning ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-12089-w
更新日期：2017-09-18 00:00:00
abstract：:We investigate the role of the spatial evolution of the acoustic field in stimulated Brillouin scattering processes in short high-gain structures. When the gain is strong enough that the gain length becomes comparable to the acoustic wave decay length of order 100 microns, standard approximations treating the acoustic...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep13656
更新日期：2015-09-04 00:00:00
abstract：:We collected Solidago altissima clones to explore their leaf damage resistance, and as a result identified five accessions that exhibited variable defense abilities against the generalist herbivore Spodoptera litura. In order to characterize molecules involved in such natural variation, we focused on ethylene response...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-62142-4
更新日期：2020-03-24 00:00:00
