Heritability estimates of the novel trait 'suppressed in ovo virus infection' in honey bees (Apis mellifera).

Abstract:

:Honey bees are under pressure due to abnormal high colony death rates, especially during the winter. The infestation by the Varroa destructor mite and the viruses that this ectoparasite transmits are generally considered as the bees' most important biological threats. Almost all efforts to remedy this dual infection have so far focused on the control of the Varroa mite alone and not on the viruses it transmits. In the present study, the sanitary control of breeding queens was conducted on eggs taken from drone brood for 4 consecutive years (2015-2018). The screening was performed on the sideline of an ongoing breeding program, which allowed us to estimate the heritabilities of the virus status of the eggs. We used the term 'suppressed in ovo virus infection' (SOV) for this novel trait and found moderate heritabilities for the presence of several viruses simultaneously and for the presence of single viral species. Colonies that expressed the SOV trait seemed to be more resilient to virus infections as a whole with fewer and less severe Deformed wing virus infections in most developmental stages, especially in the male caste. The implementation of this novel trait into breeding programs is recommended.

journal_name

Sci Rep

journal_title

Scientific reports

authors

de Graaf DC,Laget D,De Smet L,Claeys Boúúaert D,Brunain M,Veerkamp RF,Brascamp EW

doi

10.1038/s41598-020-71388-x

subject

Has Abstract

pub_date

2020-08-31 00:00:00

pages

14310

issue

1

issn

2045-2322

pii

10.1038/s41598-020-71388-x

journal_volume

10

pub_type

杂志文章
  • Fermi arcs vs. Fermi pockets in electron-doped perovskite iridates.

    abstract::We report on an angle resolved photoemission (ARPES) study of bulk electron-doped perovskite iridate, (Sr(1-x)La(x))3Ir2O7. Fermi surface pockets are observed with a total electron count in keeping with that expected from La substitution. Depending on the energy and polarization of the incident photons, these pockets ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep08533

    authors: He J,Hafiz H,Mion TR,Hogan T,Dhital C,Chen X,Lin Q,Hashimoto M,Lu DH,Zhang Y,Markiewicz RS,Bansil A,Wilson SD,He RH

    更新日期:2015-02-23 00:00:00

  • Chlamydia trachomatis serovars in urogenital and ocular samples collected 2014-2017 from Austrian patients.

    abstract::Infection of humans with Chlamydia trachomatis, a bacterial pathogen with a unique intracellular replication cycle, may cause a variety of clinical manifestations. These are linked to various serovars of the pathogen; trachoma to serovars A-C, oculogenital infections to serovars D-K, and lymphogranuloma venereum to se...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-54886-5

    authors: Lesiak-Markowicz I,Schötta AM,Stockinger H,Stanek G,Markowicz M

    更新日期:2019-12-04 00:00:00

  • Bromodomain inhibitor JQ1 reversibly blocks IFN-γ production.

    abstract::As a class, 'BET' inhibitors disrupt binding of bromodomain and extra-terminal motif (BET) proteins, BRD2, BRD3, BRD4 and BRDT, to acetylated histones preventing recruitment of RNA polymerase 2 to enhancers and promoters, especially super-enhancers, to inhibit gene transcription. As such, BET inhibitors may be useful ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-46516-x

    authors: Gibbons HR,Mi DJ,Farley VM,Esmond T,Kaood MB,Aune TM

    更新日期:2019-07-16 00:00:00

  • Phenotypic and genetic characterisation of an emerging reovirus from Pekin ducks in China.

    abstract::In June 2016, a disease characterised by intestinal haemorrhage with a mortality rate of approximately 5% was observed in a duck farm in Shandong province, China. Here, we report the isolation and characterisation of a reovirus from duck tissue samples by inoculating duck embryos and duck embryo fibroblasts (DEF). The...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-44178-3

    authors: Cao Y,Sun M,Wang J,Hu X,He W,Su J

    更新日期:2019-05-23 00:00:00

  • Archaeal amoA and ureC genes and their transcriptional activity in the Arctic Ocean.

    abstract::Thaumarchaeota and the gene encoding for a subunit of ammonia monooxygenase (amoA) are ubiquitous in Polar Seas, and some Thaumarchaeota also have a gene coding for ureC, diagnostic for urease. Using quantitative PCR we investigated the occurrence of genes and transcripts of ureC and amoA in Arctic samples from winter...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep04661

    authors: Pedneault E,Galand PE,Potvin M,Tremblay JÉ,Lovejoy C

    更新日期:2014-04-11 00:00:00

  • Co-extinctions annihilate planetary life during extreme environmental change.

    abstract::Climate change and human activity are dooming species at an unprecedented rate via a plethora of direct and indirect, often synergic, mechanisms. Among these, primary extinctions driven by environmental change could be just the tip of an enormous extinction iceberg. As our understanding of the importance of ecological...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-35068-1

    authors: Strona G,Bradshaw CJA

    更新日期:2018-11-13 00:00:00

  • Brain hubs in lesion models: Predicting functional network topology with lesion patterns in patients.

    abstract::Various important topological properties of healthy brain connectome have recently been identified. However, the manner in which brain lesion changes the functional network topology is unknown. We examined how critical specific brain areas are in the maintenance of network topology using multivariate support vector re...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-17886-x

    authors: Yuan B,Fang Y,Han Z,Song L,He Y,Bi Y

    更新日期:2017-12-20 00:00:00

  • Mitochondrial genomes of the key zooplankton copepods Arctic Calanus glacialis and North Atlantic Calanus finmarchicus with the longest crustacean non-coding regions.

    abstract::We determined the nearly complete mitochondrial genomes of the Arctic Calanus glacialis and its North Atlantic sibling Calanus finmarchicus, which are key zooplankton components in marine ecosystems. The sequenced part of C. glacialis mitogenome is 27,342 bp long and consists of two contigs, while for C. finmarchicus ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-13807-0

    authors: Weydmann A,Przyłucka A,Lubośny M,Walczyńska KS,Serrão EA,Pearson GA,Burzyński A

    更新日期:2017-10-20 00:00:00

  • The effect of lattice disorder on the low-temperature heat capacity of (U1-yThy)O2 and 238Pu-doped UO2.

    abstract::The low-temperature heat capacity of (U1-yThy)O2 and 238Pu-doped UO2 samples were determined using hybrid adiabatic relaxation calorimetry. Results of the investigated systems revealed the presence of the magnetic transition specific for UO2 in all three intermediate compositions of the uranium-thorium dioxide (y = 0....

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-51476-3

    authors: Vălu SO,De Bona E,Popa K,Griveau JC,Colineau E,Konings RJM

    更新日期:2019-10-21 00:00:00

  • Comparing passive measures of fatigue-like behavior in mice.

    abstract::Fatigue is a very common and costly symptom associated with various diseases and disorders. Nonetheless, understanding the pathobiology and developing of therapies for fatigue have been difficult, partly because of a lack of consensus on the measures to phenotype this behavior, both in clinical settings and in animal ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-32654-1

    authors: Wolff BS,Raheem SA,Saligan LN

    更新日期:2018-09-24 00:00:00

  • Transcriptomic analysis of 3D Cardiac Differentiation of Human Induced Pluripotent Stem Cells Reveals Faster Cardiomyocyte Maturation Compared to 2D Culture.

    abstract::Human induced pluripotent stem cells (hiPSCs) represent an almost limitless source of cells for disease modelling and drug screening applications. Here we established an efficient and robust 3D platform for cardiomyocyte (CMs) production from hiPSCs, solely through small-molecule-based temporal modulation of the Wnt s...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-45047-9

    authors: Branco MA,Cotovio JP,Rodrigues CAV,Vaz SH,Fernandes TG,Moreira LM,Cabral JMS,Diogo MM

    更新日期:2019-06-25 00:00:00

  • Regulation of Airway Inflammation by G-protein Regulatory Motif Peptides of AGS3 protein.

    abstract::Respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), and lung infections have critical consequences on mortality and morbidity in humans. The aims of the present study were to examine the mechanisms by which CXCL12 affects MUC1 transcription and airway inflammation, which depend on activa...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep27054

    authors: Choi IW,Ahn do W,Choi JK,Cha HJ,Ock MS,You E,Rhee S,Kim KC,Choi YH,Song KS

    更新日期:2016-06-07 00:00:00

  • New noninvasive index for predicting liver fibrosis in Asian patients with chronic viral hepatitis.

    abstract::We developed an optimal noninvasive index comprising routine laboratory parameters for predicting cirrhosis in chronic hepatitis B (CHB) and chronic hepatitis C (CHC) patients. This study included 992 CHB patients and 1,284 CHC patients who received liver biopsy. We developed the new index, named modified Fibrosis-4 (...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-03589-w

    authors: Wang HW,Peng CY,Lai HC,Su WP,Lin CH,Chuang PH,Chen SH,Chen CH,Hsu WF,Huang GT

    更新日期:2017-06-12 00:00:00

  • Hybridization between alien species Rumex obtusifolius and closely related native vulnerable species R. longifolius in a mountain tourist destination.

    abstract::Alien species expand their distribution by transportation network development. Hybridization between alien species Rumex obtusifolius and closely related native vulnerable species R. longifolius was examined in a mountain tourist destination in central Japan. The three taxa were morphologically identified in the field...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep13898

    authors: Takahashi K,Hanyu M

    更新日期:2015-09-10 00:00:00

  • Muscle-specific overexpression of AdipoR1 or AdipoR2 gives rise to common and discrete local effects whilst AdipoR2 promotes additional systemic effects.

    abstract::Hypoadiponectinemia and adiponectin resistance are implicated in the aetiology of obesity-related cardiometabolic disorders, hence represent a potential therapeutic axis. Here we characterised the effects of in vivo electrotransfer-mediated overexpression of the adiponectin receptors, AdipoR1 or AdipoR2, into tibialis...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep41792

    authors: Keshvari S,Henstridge DC,Ng C,Febbraio MA,Whitehead JP

    更新日期:2017-02-01 00:00:00

  • Spatiotemporal disturbance characteristics determine functional stability and collapse risk of simulated microbial ecosystems.

    abstract::Terrestrial microbial ecosystems are exposed to many types of disturbances varying in their spatial and temporal characteristics. The ability to cope with these disturbances is crucial for maintaining microbial ecosystem functions, especially if disturbances recur regularly. Thus, understanding microbial ecosystem dyn...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-27785-4

    authors: König S,Worrich A,Banitz T,Centler F,Harms H,Kästner M,Miltner A,Wick LY,Thullner M,Frank K

    更新日期:2018-06-22 00:00:00

  • Pushing the limit: examining factors that affect anoxia tolerance in a single genotype of adult D. melanogaster.

    abstract::Drosophila melanogaster is a promiscuous species that inhabits a large range of harsh environments including flooded habitats and varying temperature changes. To survive these environments, fruit flies have adapted mechanisms of tolerance that allow them to thrive. During exposure to anoxic stress, fruit flies and oth...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep09204

    authors: Benasayag-Meszaros R,Risley MG,Hernandez P,Fendrich M,Dawson-Scully K

    更新日期:2015-03-17 00:00:00

  • New Approaches for Quantitative Reconstruction of Radiation Dose in Human Blood Cells.

    abstract::In the event of a nuclear attack or large-scale radiation event, there would be an urgent need for assessing the dose to which hundreds or thousands of individuals were exposed. Biodosimetry approaches are being developed to address this need, including transcriptomics. Studies have identified many genes with potentia...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-54967-5

    authors: Ghandhi SA,Shuryak I,Morton SR,Amundson SA,Brenner DJ

    更新日期:2019-12-05 00:00:00

  • Predictive feedback to V1 dynamically updates with sensory input.

    abstract::Predictive coding theories propose that the brain creates internal models of the environment to predict upcoming sensory input. Hierarchical predictive coding models of vision postulate that higher visual areas generate predictions of sensory inputs and feed them back to early visual cortex. In V1, sensory inputs that...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-16093-y

    authors: Edwards G,Vetter P,McGruer F,Petro LS,Muckli L

    更新日期:2017-11-28 00:00:00

  • Molecular evolution of gas cavity in [NiFeSe] hydrogenases resurrected in silico.

    abstract::Oxygen tolerance of selenium-containing [NiFeSe] hydrogenases (Hases) is attributable to the high reducing power of the selenocysteine residue, which sustains the bimetallic Ni-Fe catalytic center in the large subunit. Genes encoding [NiFeSe] Hases are inherited by few sulphate-reducing δ-proteobacteria globally distr...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep19742

    authors: Tamura T,Tsunekawa N,Nemoto M,Inagaki K,Hirano T,Sato F

    更新日期:2016-01-28 00:00:00

  • Capturing PM2.5 Emissions from 3D Printing via Nanofiber-based Air Filter.

    abstract::This study investigated the feasibility of using polycaprolactone (PCL) nanofiber-based air filters to capture PM2.5 particles emitted from fused deposition modeling (FDM) 3D printing. Generation and aggregation of emitted particles were investigated under different testing environments. The results show that: (1) the...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-10995-7

    authors: Rao C,Gu F,Zhao P,Sharmin N,Gu H,Fu J

    更新日期:2017-09-04 00:00:00

  • A genetic variant of miR-148a binding site in the SCRN1 3'-UTR is associated with susceptibility and prognosis of gastric cancer.

    abstract::Single nucleotide polymorphisms (SNPs) in the 3'-untranslated regions targeted by putative mircoRNA can change its binding strength, affecting the susceptibility and prognosis of cancer. We aimed to investigate the associations between SNPs within miR-148a binding sites and gastric cancer (GC) risk and prognosis. Usin...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep07080

    authors: Song P,Zhu H,Zhang D,Chu H,Wu D,Kang M,Wang M,Gong W,Zhou J,Zhang Z,Zhao Q

    更新日期:2014-11-17 00:00:00

  • Global identification of a marine diatom long noncoding natural antisense transcripts (NATs) and their response to phosphate fluctuations.

    abstract::Often ignored and regarded as mere transcriptional noise, long noncoding RNAs (lncRNAs) are starting to be considered key regulators of gene expression across the Eukarya domain of life. In the model diatom Phaeodactylum tricornutum, we have previously reported the occurrence of 1,510 intergenic lncRNAs (lincRNAs), ma...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-71002-0

    authors: Cruz de Carvalho MH,Bowler C

    更新日期:2020-08-24 00:00:00

  • High yield extraction of pure spinal motor neurons, astrocytes and microglia from single embryo and adult mouse spinal cord.

    abstract::Extraction of mouse spinal motor neurons from transgenic mouse embryos recapitulating some aspects of neurodegenerative diseases like amyotrophic lateral sclerosis has met with limited success. Furthermore, extraction and long-term culture of adult mouse spinal motor neurons and glia remain also challenging. We presen...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep16763

    authors: Beaudet MJ,Yang Q,Cadau S,Blais M,Bellenfant S,Gros-Louis F,Berthod F

    更新日期:2015-11-18 00:00:00

  • Arsenite-loaded nanoparticles inhibit PARP-1 to overcome multidrug resistance in hepatocellular carcinoma cells.

    abstract::Hepatocellular carcinoma (HCC) is one of the highest incidences in cancers; however, traditional chemotherapy often suffers from low efficiency caused by drug resistance. Herein, we report an arsenite-loaded dual-drug (doxorubicin and arsenic trioxide, i.e., DOX and ATO) nanomedicine system (FeAsOx@SiO2-DOX, Combo NP)...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep31009

    authors: Liu H,Zhang Z,Chi X,Zhao Z,Huang D,Jin J,Gao J

    更新日期:2016-08-03 00:00:00

  • Differential lactate and cholesterol synthetic activities in XY and XX Sertoli cells.

    abstract::SRY, a sex-determining gene, induces testis development in chromosomally female (XX) individuals. However, mouse XX Sertoli cells carrying Sry (XX/Sry Sertoli cells) are incapable of fully supporting germ cell development, even when the karyotype of the germ cells is XY. While it has therefore been assumed that XX/Sry...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep41912

    authors: Shishido Y,Baba T,Sato T,Shima Y,Miyabayashi K,Inoue M,Akiyama H,Kimura H,Kanai Y,Ishihara Y,Haraguchi S,Miyazaki A,Rozman D,Yamazaki T,Choi MH,Ohkawa Y,Suyama M,Morohashi KI

    更新日期:2017-02-02 00:00:00

  • Onset of summer monsoon in Northeast India is preceded by enhanced transpiration.

    abstract::Variations in isotopic composition of water vapor in the atmosphere is an important indicator of the processes within the hydrological cycle. Isotopic signature of water vapor and precipitation can be helpful in partitioning evaporation and transpiration fluxes. It is well known that transpiration from forested region...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-55186-8

    authors: Pradhan R,Singh N,Singh RP

    更新日期:2019-12-09 00:00:00

  • The differential effects of isoflurane and sevoflurane on neonatal mice.

    abstract::Previous research has shown that exposure to volatile anesthetics can induce acute neuroinflammation and neuroapoptopsis in neonatal rodents and that these events can lead to cognitive dysfunction at later stages. Isoflurane and sevoflurane are two of the most popular anesthetics used in the field of pediatrics. Howev...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-76147-6

    authors: Zhao S,Fan Z,Hu J,Zhu Y,Lin C,Shen T,Li Z,Li K,Liu Z,Chen Y,Zhang B

    更新日期:2020-11-09 00:00:00

  • New method for visualizing the dose rate distribution around the Fukushima Daiichi Nuclear Power Plant using artificial neural networks.

    abstract::This study proposes a new method of visualizing the ambient dose rate distribution using artificial neural networks (ANNs) from airborne radiation monitoring results. The method was applied to the results of the airborne radiation monitoring which was conducted around the Fukushima Daiichi Nuclear Power Plant by an un...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-021-81546-4

    authors: Sasaki M,Sanada Y,Katengeza EW,Yamamoto A

    更新日期:2021-01-20 00:00:00

  • Ferromagnetism of Fe3Sn and alloys.

    abstract::Hexagonal Fe(3)Sn has many of the desirable properties for a new permanent magnet phase with a Curie temperature of 725 K, a saturation moment of 1.18 MA/m. and anisotropy energy, K1 of 1.8 MJ/m(3). However, contrary to earlier experimental reports, we found both experimentally and theoretically that the easy magnetic...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep07024

    authors: Sales BC,Saparov B,McGuire MA,Singh DJ,Parker DS

    更新日期:2014-11-12 00:00:00