Fatigability and functional performance among older adults with low-normal ankle-brachial index: Cross-sectional findings from the Baltimore Longitudinal Study of Aging.

abstract：AIMS:Besides carotid or cardiac embolism, stroke can occur via microangiopathy (small arterial disease [SAD]) and macroangiopathy (intracranial atherosclerotic stroke [ICAS]) of the intracranial vasculature. There have been efforts to identify risk factors specific to microangiopathy and macroangiopathy, including vasc...

journal_title：Atherosclerosis

authors： Bang OY,Chung JW,Ryoo S,Moon GJ,Kim GM,Chung CS,Lee KH

更新日期：2016-03-01 00:00:00

abstract：:The effect of prostaglandins (PG) on initiation of DNA synthesis in arterial smooth muscle cells (SMC) stimulated with platelet-derived growth factor (PDGF) was examined. A concentration of 10 ng/ml PGE1 inhibited DNA synthesis, measured as autoradiographically labeled nuclei, by about 70%. Similar results were obtain...

journal_title：Atherosclerosis

authors： Nilsson J,Olsson AG

更新日期：1984-10-01 00:00:00

abstract：:This study was undertaken to determine whether sialic acid removal alters the catabolism of low density lipoprotein in humans. Human low density lipoproteins labeled in vitro with 125I were incubated in the presence (termed desialylated) or absence (sialylated) of neuraminidase. The treatment with neuraminidase from C...

journal_title：Atherosclerosis

authors： Malmendier CL,Delcroix C,Fontaine M

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND:Circulating endotoxin levels are associated with atherosclerosis. Moreover, ethnic differences in pro-inflammatory markers may be associated with ethnic differences in atherosclerotic and cardiovascular (CVD) and coronary heart disease (CHD) risk. OBJECTIVE AND METHODS:To investigate ethnic differences in c...

journal_title：Atherosclerosis

authors： Miller MA,McTernan PG,Harte AL,Silva NF,Strazzullo P,Alberti KG,Kumar S,Cappuccio FP

更新日期：2009-04-01 00:00:00

abstract：:Early stages of atherosclerosis are commonly noted in youth. The present study was designed to examine the effects of lifestyle modification in 19 overweight children (age 8-17) who were placed on a high-fiber, low-fat diet in a 2-week residential program where food was provided ad libitum and daily exercise (2-2.5h) ...

journal_title：Atherosclerosis

authors： Roberts CK,Chen AK,Barnard RJ

更新日期：2007-03-01 00:00:00

abstract：:In 137 living subjects, arteriosclerotic change in the human abdominal aorta was examined in relation to coronary heart disease (CHD) using a new ultrasonic method. The pressure strain elastic modulus (Ep) was calculated as an index of elastic properties from which arteriosclerotic change in the aorta was estimated. T...

journal_title：Atherosclerosis

authors： Imura T,Yamamoto K,Satoh T,Mikami T,Yasuda H

更新日期：1988-10-01 00:00:00

abstract：OBJECTIVES:To explore the therapeutic potential of fibrates to attenuate premature atherosclerosis and cardiovascular disease in the atherogenic dyslipidemias typical of Type II diabetes, Metabolic Syndrome, and the Type IIB (mixed) lipid phenotype; such dyslipidemias frequently feature peripheral insulinoresistance. ...

journal_title：Atherosclerosis

authors： Chapman MJ

更新日期：2003-11-01 00:00:00

abstract：:Coronary heart disease (CHD) is one of the leading disorders with the highest mortality rate. Percutaneous angioplasty and stent implantation are the currently available standard methods for the treatment of obstructive coronary artery disease. However, the stent being an exogenous substance causes several complicatio...

journal_title：Atherosclerosis

authors： Liu S,Yang Y,Jiang S,Tang N,Tian J,Ponnusamy M,Tariq MA,Lian Z,Xin H,Yu T

更新日期：2018-05-01 00:00:00

abstract：:High-density lipoprotein (HDL) cholesteryl esters (CE) are taken up by many cells without parallel uptake of HDL apolipoproteins. This selective uptake of HDL CE was investigated in human monocyte-derived macrophages (HMM). HDL3 (d = 1.125-1.21 g/ml) was labeled in its apolipoprotein A-I moiety with 125I and in its CE...

journal_title：Atherosclerosis

authors： Rinninger F,Deichen JT,Jäckle S,Windler E,Greten H

更新日期：1994-02-01 00:00:00

abstract：:The metabolism of homocysteine requires contributions of several enzymes and vitamin cofactors. Earlier studies identified a common polymorphism of methylenetetrahydrofolate reductase that was associated with mild hyperhomocysteinemia. Common variants of two other enzymes involved in homocysteine metabolism, methionin...

journal_title：Atherosclerosis

authors： Jacques PF,Bostom AG,Selhub J,Rich S,Ellison RC,Eckfeldt JH,Gravel RA,Rozen R,National Heart, Lung and Blood Institute, National Institutes of Health.

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Several risk prediction models for coronary heart disease (CHD) are available today, however, they only explain a modest proportion of the incidence. Circulating microRNAs (miRs) have recently been associated with processes in CHD development, and may therefore represent new potential risk markers. ...

journal_title：Atherosclerosis

authors： Velle-Forbord T,Eidlaug M,Debik J,Sæther JC,Follestad T,Nauman J,Gigante B,Røsjø H,Omland T,Langaas M,Bye A

更新日期：2019-10-01 00:00:00

abstract：:Variations of circulating C-reactive protein (CRP) levels are supposed to reflect chronic inflammatory process of the cardiovascular system. In particular, it has been reported that high-sensitivity CRP (hsCRP) is a promising marker of coronary heart disease. In the present study, we assessed the relationship between ...

journal_title：Atherosclerosis

authors： Saito M,Ishimitsu T,Minami J,Ono H,Ohrui M,Matsuoka H

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND AND AIMS:The pathogenesis of abdominal aortic aneurysm (AAA) shares several common pathways with atherosclerosis. Prospective clinical plasma biomarker studies in AAA have been hampered by the need for very large cohorts and long follow-up time. METHODS:We analyzed a prospective longitudinal cohort of middl...

journal_title：Atherosclerosis

authors： Acosta S,Taimour S,Gottsäter A,Persson M,Engström G,Melander O,Zarrouk M,Nilsson PM,Smith JG

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:A significant proportion of women with angina-like chest pain and angiographically normal coronary arteries have microvascular dysfunction as detected by reduced coronary blood flow reserve (CFR). Classical clinical risk factors of atherosclerosis poorly predict this scenario. We sought to assess whether incr...

journal_title：Atherosclerosis

authors： Sade LE,Eroglu S,Bozbaş H,Ozbiçer S,Hayran M,Haberal A,Müderrisoğlu H

更新日期：2009-06-01 00:00:00

abstract：:The oxidation of low density lipoprotein (LDL) is believed to be an important process in the development and progression of atherosclerosis. In this study, human subjects were supplemented daily with one of: 6 g raw garlic; 2.4 g aged garlic extract (AGE); or 0.8 g DL-alpha-tocopherol acetate for 7 days to determine t...

journal_title：Atherosclerosis

authors： Munday JS,James KA,Fray LM,Kirkwood SW,Thompson KG

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVE:Interleukin (IL)-6 is a key modulator of the acute phase response (APR), and while both are implicated in atherosclerosis, the pathological role of specific IL-6 signalling cascades is ill-defined. Since IL-6 employs the cytokine receptor gp130 to primarily activate the STAT3 pathway, here we evaluate whether...

journal_title：Atherosclerosis

authors： Jones GW,McLeod L,Kennedy CL,Bozinovski S,Najdovska M,Jenkins BJ

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:To evaluate the impact of familial hypercholesterolemia (FH) and familial combined hyperlipidemia (FCH) on arterial properties and the effects of statins. METHODS:We meta-analyzed 51 studies providing data for 4,057 FH patients and 732 FCH patients with random-effects models, meta-regression analysis and pu...

journal_title：Atherosclerosis

authors： Masoura C,Pitsavos C,Aznaouridis K,Skoumas I,Vlachopoulos C,Stefanadis C

更新日期：2011-01-01 00:00:00

abstract：:VPS10P domain receptors are a unique class of sorting receptors that direct intracellular transport of target proteins in neurons and that play central roles in neurodegenerative processes. Surprisingly, genome-wide association studies now implicate the very same receptors in cardiovascular and metabolic disturbances....

journal_title：Atherosclerosis

authors： Schmidt V,Willnow TE

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Galectin-3 binding protein (Gal-3BP) has been associated with inflammation and cancer, however, its role in coronary artery disease (CAD) and cardiovascular outcome remains unclear. METHODS:Gal-3BP plasma levels were measured by ELISA in 2922 individuals from the LURIC study (62.7 ± 10.6 years, 62....

journal_title：Atherosclerosis

authors： Gleissner CA,Erbel C,Linden F,Domschke G,Akhavanpoor M,Helmes CM,Doesch AO,Kleber ME,Katus HA,Maerz W

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Micro-particles (MP) are secreted by various cells. Their biological roles in health and in disease remain unknown. Here we describe formation of MP in the process of ABCA1-dependent cholesterol efflux in different cell types. METHODS:The ATP-binding cassette transporter, subfamily A, member 1 (ABC...

journal_title：Atherosclerosis

authors： Hafiane A,Genest J

更新日期：2017-02-01 00:00:00

abstract：UNLABELLED:Transglutaminases play an important role in vascular remodeling, calcification, cell adhesion and endothelial barrier function. In this study we investigate the influence of combined inhibition of both tissue-type transglutaminase (TG2) and the plasma transglutaminase FXIIIA on early lesion development. MET...

journal_title：Atherosclerosis

authors： Matlung HL,VanBavel E,van den Akker J,de Vries CJ,Bakker EN

更新日期：2010-11-01 00:00:00

abstract：:The hypolipidemic response of rice bran oil (RBO) was investigated in nonhuman primates fed semi-purified diets containing blends of oils which included RBO at 0-35% Kcals as dietary fat. The studies demonstrated the following: (a) the degree of reduction of serum total cholesterol (TC) and low density lipoprotein cho...

journal_title：Atherosclerosis

authors： Nicolosi RJ,Ausman LM,Hegsted DM

更新日期：1991-06-01 00:00:00

abstract：:In general, plasma concentrations of high density lipoproteins (HDL) are inversely related to the incidence of coronary artery disease. One exception to this trend is individuals with apolipoprotein A-I(Milano) (apo A-IM), a molecular variant of apo A-I, which results in very low plasma apo A-I and HDL-cholesterol lev...

journal_title：Atherosclerosis

authors： Chiesa G,Stoltzfus LJ,Michelagnoli S,Bielicki JK,Santi M,Forte TM,Sirtori CR,Franceschini G,Rubin EM

更新日期：1998-01-01 00:00:00

abstract：:Rabbit apolipoprotein A-I (apo A-I) of molecular weight 27,612 contained 241 amino acids. In contrast to its human counterpart which has 3 methionine residues, the rabbit protein possesses only one and therefore produces 2 fragments after CNBr cleavage (CNBr I and II, NH2- and COOH-terminal, respectively). From a seri...

journal_title：Atherosclerosis

authors： Leroy A,Vu-Dac N,Theret N,Pio F,Fruchart JC

更新日期：1989-09-01 00:00:00

abstract：:We tested whether low high-density lipoprotein cholesterol (HDL-C) and/or high triglycerides are associated to abnormal HDL subclasses distribution and composition, and their relationships with fasting insulin and C-reactive protein (CRP). Four groups of adolescents were studied: group 1 (HDL-C< or =35 mg/dl+TG> or =1...

journal_title：Atherosclerosis

authors： Medina-Urrutia A,Juarez-Rojas JG,Martínez-Alvarado R,Jorge-Galarza E,Posadas-Sánchez R,Cardoso-Saldaña G,Caracas-Portilla N,Mendoza-Perez E,Posadas-Romero C

更新日期：2008-12-01 00:00:00

abstract：:The composition of very low density lipoproteins (VLDL: d less than 1.019) of New Zealand male rabbits reciving cholesterol (2 g/day) and metformin (135 mg/kg/day) is investigated. These rabbits, while showing only a slight reduction of plasma cholesterol levels, as compared to cholesterol-fed (h.c.) animals, show a m...

journal_title：Atherosclerosis

authors： Sirtori CR,Catapano A,Ghiselli GC,Innocenti AL,Rodriguez J

更新日期：1977-01-01 00:00:00

abstract：:The aims of this study were to determine whether non-invasive measurement of endothelial function in conduit arteries reflects that of subcutaneous resistance arteries measured in vitro and to examine whether there is an endothelial dysfunction also in resistance arteries in patients with a previous myocardial infarct...

journal_title：Atherosclerosis

authors： Agewall S,Henareh L,Kublickiene K

更新日期：2006-01-01 00:00:00

abstract：:Baroreceptor sensitivity was studied in twelve young normotensive subjects and forty hypertensive patients, separated into two groups according to their age, severity of hypertension and signs of severe atherosclerotic vascular disease. Under stabilized circulatory conditions, the changes of pulse rate in response to ...

journal_title：Atherosclerosis

authors： Vlachakis ND,Mendlowitz M,DGuia D,DGusman D

更新日期：1976-07-01 00:00:00

abstract：:Elevated serum cholesterol is a risk factor in the development of coronary artery disease. Magnesium has been reported to decrease total serum cholesterol, low density lipoprotein, and very low density lipoprotein, and increase high density lipoprotein. A randomized, double-blind, placebo-controlled, crossover study w...

journal_title：Atherosclerosis

authors： Marken PA,Weart CW,Carson DS,Gums JG,Lopes-Virella MF

更新日期：1989-05-01 00:00:00

abstract：:Hypercholesterolemia impairs endothelial function. However, the production/release of nitric oxide from the hypercholesterolemic aorta is reported to be enhanced rather than impaired in animal studies. L-arginine improves endothelial function in hypercholesterolemic subjects. The goal of the present study was to inves...

journal_title：Atherosclerosis

authors： Kawano H,Motoyama T,Hirai N,Kugiyama K,Yasue H,Ogawa H

更新日期：2002-04-01 00:00:00