RAS and PD-L1: A Masters' Liaison in Cancer Immune Evasion.

Abstract:

:Mutant RAS is a major oncoprotein in human cancer and PD-L1 is a key driver of cancer immune evasion. In this issue of Immunity, Coelho et al. (2017) demonstrate that oncogenic RAS signaling promotes tumor immune escape by stabilizing PD-L1 mRNA.

journal_name

Immunity

journal_title

Immunity

authors

Glodde N,Hölzel M

doi

10.1016/j.immuni.2017.12.001

subject

Has Abstract

pub_date

2017-12-19 00:00:00

pages

1007-1009

issue

6

eissn

1074-7613

issn

1097-4180

pii

S1074-7613(17)30530-7

journal_volume

47

pub_type

评论,杂志文章

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