Human tyk2 kinase deficiency: another primary immunodeficiency syndrome.

Abstract:

:Janus kinases are critical for cytokine signaling. Mutations of Jak3 cause primary immunodeficiency, but Minegishi et al. (2006) now show that mutation of another Jak, tyrosine kinase 2, underlies another human immunodeficiency syndrome.

journal_name

Immunity

journal_title

Immunity

authors

Watford WT,O'Shea JJ

doi

10.1016/j.immuni.2006.10.007

subject

Has Abstract

pub_date

2006-11-01 00:00:00

pages

695-7

issue

5

eissn

1074-7613

issn

1097-4180

pii

S1074-7613(06)00479-1

journal_volume

25

pub_type

杂志文章,评审

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