Abstract:
:Two new ergostane-type sterols; (22E)-5α,6α-epoxyergosta-8,14,22-triene-3β,7β-diol (1) and 5α,6α-epoxyergost-8(14)-ene-3β,7α-diol (2) were isolated from the fruiting bodies of king trumpet mushroom (Pleurotus eryngii), along with eight known compounds (3-10). All isolated compounds were evaluated for their inhibitory effects on aromatase. Among them, 4 and 6 exhibited comparable aromatase inhibitory activities to aminoglutethimide.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Kikuchi T,Motoyashiki N,Yamada T,Shibatani K,Ninomiya K,Morikawa T,Tanaka Rdoi
10.3390/ijms18112479subject
Has Abstractpub_date
2017-11-21 00:00:00issue
11issn
1422-0067pii
ijms18112479journal_volume
18pub_type
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