Abstract：
:Aminoethylcysteine ketimine decarboxylated dimer is a natural sulfur-containing compound detected in human plasma and urine, in mammalian brain and in many common edible vegetables. Over the past decade many studies have been undertaken to identify its metabolic role. Attention has been focused on its antioxidant properties and on its reactivity against oxygen and nitrogen reactive species. These properties have been studied in different model systems starting from plasma lipoproteins to specific cellular lines. All these studies report that aminoethylcysteine ketimine decarboxylated dimer is able to interact both with reactive oxygen and nitrogen species (hydrogen peroxide, superoxide anion, hydroxyl radical, peroxynitrite and its derivatives). Its antioxidant activity is similar to that of Vitamin E while higher than other hydrophilic antioxidants, such as trolox and N-acetylcysteine.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Macone A,Fontana M,Barba M,Botta B,Nardini M,Ghirga F,Calcaterra A,Pecci L,Matarese RMdoi
10.3390/ijms12053072subject
Has Abstractpub_date
2011-01-01 00:00:00pages
3072-84issue
5issn
1422-0067pii
ijms-12-03072journal_volume
12pub_type
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