Erratum: Observation of ultrahigh mobility surface states in a topological crystalline insulator by infrared spectroscopy.

abstract：:Optogenetics has emerged as an alternative method for electrical control of the heart, where illumination is used to elicit a bioelectric response in tissue modified to express photosensitive proteins (opsins). This technology promises to enable evocation of spatiotemporally precise responses in targeted cells or tiss...

journal_title：Nature communications

authors： Boyle PM,Williams JC,Ambrosi CM,Entcheva E,Trayanova NA

更新日期：2013-01-01 00:00:00

abstract：:Rapid and, in many cases, unprecedented Arctic climate changes are having far-reaching impacts on natural and human systems. Despite state-of-the-art climate models capturing the rapid nature of Arctic climate change, termed Arctic amplification, they significantly disagree on its magnitude. Using a regional, process-...

journal_title：Nature communications

authors： Boeke RC,Taylor PC

更新日期：2018-11-27 00:00:00

abstract：:Currently, there is no comprehensive framework to evaluate the evolutionary forces acting on genomic regions associated with human complex traits and contextualize the relationship between evolution and molecular function. Here, we develop an approach to test for signatures of diverse evolutionary forces on trait-asso...

journal_title：Nature communications

authors： LaBella AL,Abraham A,Pichkar Y,Fong SL,Zhang G,Muglia LJ,Abbot P,Rokas A,Capra JA

更新日期：2020-07-24 00:00:00

abstract：:Malignant pleural effusion (MPE) is a frequent metastatic manifestation of human cancers. While we previously identified KRAS mutations as molecular culprits of MPE formation, the underlying mechanism remained unknown. Here, we determine that non-canonical IKKα-RelB pathway activation of KRAS-mutant tumor cells mediat...

journal_title：Nature communications

authors： Marazioti A,Lilis I,Vreka M,Apostolopoulou H,Kalogeropoulou A,Giopanou I,Giotopoulou GA,Krontira AC,Iliopoulou M,Kanellakis NI,Agalioti T,Giannou AD,Jones-Paris C,Iwakura Y,Kardamakis D,Blackwell TS,Taraviras S,Spella M

更新日期：2018-02-14 00:00:00

abstract：:The integration of β-barrel proteins into the bacterial outer membrane (OM) is catalysed by the β-barrel assembly machinery (BAM). The central BAM subunit (BamA) itself contains a β-barrel domain that is essential for OM protein biogenesis, but its mechanism of action is unknown. To elucidate its function, here we dev...

journal_title：Nature communications

authors： Doyle MT,Bernstein HD

更新日期：2019-07-26 00:00:00

abstract：:A diversity of self-propelled chemical motors, based on Marangoni propulsive forces, has been developed in recent years. However, most motors are non-functional due to poor performance, a lack of control, and the use of toxic materials. To overcome these limitations, we have developed multifunctional and biodegradable...

journal_title：Nature communications

authors： Pena-Francesch A,Giltinan J,Sitti M

更新日期：2019-07-18 00:00:00

abstract：:The yeast Saccharomyces cerevisiae has been an essential component of human civilization because of its long global history of use in food and beverage fermentation. However, the diversity and evolutionary history of the domesticated populations of the yeast remain elusive. We show here that China/Far East Asia is lik...

journal_title：Nature communications

authors： Duan SF,Han PJ,Wang QM,Liu WQ,Shi JY,Li K,Zhang XL,Bai FY

更新日期：2018-07-12 00:00:00

abstract：:Viruses cause 10-15% of all human cancers. Massively parallel sequencing has recently proved effective for uncovering novel viruses and virus-tumour associations, but this approach has not yet been applied to comprehensive patient cohorts. Here we screen a diverse landscape of human cancer, encompassing 4,433 tumours ...

journal_title：Nature communications

authors： Tang KW,Alaei-Mahabadi B,Samuelsson T,Lindh M,Larsson E

更新日期：2013-01-01 00:00:00

abstract：:NaK and other non-selective channels are able to conduct both sodium (Na+) and potassium (K+) with equally high efficiency. In contrast to previous crystallographic results, we show that the selectivity filter (SF) of NaK in native-like lipid membranes adopts two distinct conformations that are stabilized by either Na...

journal_title：Nature communications

authors： Shi C,He Y,Hendriks K,de Groot BL,Cai X,Tian C,Lange A,Sun H

更新日期：2018-02-19 00:00:00

abstract：:Generating a comprehensive map of molecular interactions in living cells is difficult and great efforts are undertaken to infer molecular interactions from large-scale perturbation experiments. Here, we develop the analytical and numerical tools to quantify the fundamental limits for inferring transcriptional networks...

journal_title：Nature communications

authors： Blum CF,Heramvand N,Khonsari AS,Kollmann M

更新日期：2018-01-09 00:00:00

abstract：:Solid organic matter (OM) plays an essential role in the generation, migration, storage, and production of hydrocarbons from economically important shale rock formations. Electron microscopy images have documented spatial heterogeneity in the porosity of OM at nanoscale, and bulk spectroscopy measurements have documen...

journal_title：Nature communications

authors： Yang J,Hatcherian J,Hackley PC,Pomerantz AE

更新日期：2017-12-19 00:00:00

abstract：:Isolated populations can empower the identification of rare variation associated with complex traits through next generation association studies, but the generalizability of such findings remains unknown. Here we genotype 1,267 individuals from a Greek population isolate on the Illumina HumanExome Beadchip, in search ...

journal_title：Nature communications

authors： Tachmazidou I,Dedoussis G,Southam L,Farmaki AE,Ritchie GR,Xifara DK,Matchan A,Hatzikotoulas K,Rayner NW,Chen Y,Pollin TI,O'Connell JR,Yerges-Armstrong LM,Kiagiadaki C,Panoutsopoulou K,Schwartzentruber J,Moutsianas L,UK1

更新日期：2013-01-01 00:00:00

abstract：:Roughly a third (~30 ppm) of the carbon dioxide (CO2) that entered the ocean during ice ages is attributed to biological mechanisms. A leading hypothesis for the biological drawdown of CO2 is iron (Fe) fertilisation of the high latitudes, but modelling efforts attribute at most 10 ppm to this mechanism, leaving ~20 pp...

journal_title：Nature communications

authors： Buchanan PJ,Chase Z,Matear RJ,Phipps SJ,Bindoff NL

更新日期：2019-10-10 00:00:00

abstract：:Two-dimensional electron systems have attracted attention as thermoelectric materials, which can directly convert waste heat into electricity. It has been theoretically predicted that thermoelectric power factor can be largely enhanced when the two-dimensional electron layer is far narrower than the de Broglie wavelen...

journal_title：Nature communications

authors： Zhang Y,Feng B,Hayashi H,Chang CP,Sheu YM,Tanaka I,Ikuhara Y,Ohta H

更新日期：2018-06-20 00:00:00

abstract：:Hundreds of clinical studies have demonstrated associations between the human microbiome and disease, yet fundamental questions remain on how we can generalize this knowledge. Results from individual studies can be inconsistent, and comparing published data is further complicated by a lack of standard processing and a...

journal_title：Nature communications

authors： Duvallet C,Gibbons SM,Gurry T,Irizarry RA,Alm EJ

更新日期：2017-12-05 00:00:00

abstract：:Proton conduction is a fundamental process in biology and in devices such as proton exchange membrane fuel cells. To maximize proton conduction, three-dimensional conduction pathways are preferred over one-dimensional pathways, which prevent conduction in two dimensions. Many crystalline porous solids to date show one...

journal_title：Nature communications

authors： Liu M,Chen L,Lewis S,Chong SY,Little MA,Hasell T,Aldous IM,Brown CM,Smith MW,Morrison CA,Hardwick LJ,Cooper AI

更新日期：2016-09-13 00:00:00

abstract：:16p11.2 and 22q11.2 Copy Number Variants (CNVs) confer high risk for Autism Spectrum Disorder (ASD), schizophrenia (SZ), and Attention-Deficit-Hyperactivity-Disorder (ADHD), but their impact on functional connectivity (FC) remains unclear. Here we report an analysis of resting-state FC using magnetic resonance imaging...

journal_title：Nature communications

authors： Moreau CA,Urchs SGW,Kuldeep K,Orban P,Schramm C,Dumas G,Labbe A,Huguet G,Douard E,Quirion PO,Lin A,Kushan L,Grot S,Luck D,Mendrek A,Potvin S,Stip E,Bourgeron T,Evans AC,Bearden CE,Bellec P,Jacquemont S

更新日期：2020-10-19 00:00:00

abstract：:Blends of electron-donating and -accepting organic semiconductors are widely used as photoactive materials in next-generation solar cells and photodetectors. The yield of free charges in these systems is often determined by the separation of interfacial electron-hole pairs, which is expected to depend on the ability o...

journal_title：Nature communications

authors： Stolterfoht M,Armin A,Shoaee S,Kassal I,Burn P,Meredith P

更新日期：2016-06-21 00:00:00

abstract：:The proliferative and functional heterogeneity among seemingly uniform cells is a universal phenomenon. Identifying the underlying factors requires single-cell analysis of function and proliferation. Here we show that the pancreatic beta-cells in zebrafish exhibit different growth-promoting and functional properties, ...

journal_title：Nature communications

authors： Singh SP,Janjuha S,Hartmann T,Kayisoglu Ö,Konantz J,Birke S,Murawala P,Alfar EA,Murata K,Eugster A,Tsuji N,Morrissey ER,Brand M,Ninov N

更新日期：2017-09-22 00:00:00

abstract：:The neuromodulator serotonin (5-HT) has been implicated in a variety of functions that involve patience or impulse control. Many of these effects are consistent with a long-standing theory that 5-HT promotes behavioral inhibition, a motivational bias favoring passive over active behaviors. To further test this idea, w...

journal_title：Nature communications

authors： Lottem E,Banerjee D,Vertechi P,Sarra D,Lohuis MO,Mainen ZF

更新日期：2018-03-08 00:00:00

abstract：:The original version of this Article contained errors in Fig. 3. In panel a, bars from a chart depicting the percentage of antibody-positive individuals in non-infectious and infectious groups were inadvertently included in place of bars depicting the percentage of infectious individuals, as described in the Article a...

journal_title：Nature communications

authors： Stone WJR,Campo JJ,Ouédraogo AL,Meerstein-Kessel L,Morlais I,Da D,Cohuet A,Nsango S,Sutherland CJ,van de Vegte-Bolmer M,Siebelink-Stoter R,van Gemert GJ,Graumans W,Lanke K,Shandling AD,Pablo JV,Teng AA,Jones S,de Jong

更新日期：2018-04-11 00:00:00

abstract：:The Hippo pathway is an evolutionarily conserved regulator of organ size and tumorigenesis that negatively regulates cell growth and survival. Here we report that Yes-associated protein (YAP), the terminal effector of the Hippo pathway, interacts with FoxO1 in the nucleus of cardiomyocytes, thereby promoting survival....

journal_title：Nature communications

authors： Shao D,Zhai P,Del Re DP,Sciarretta S,Yabuta N,Nojima H,Lim DS,Pan D,Sadoshima J

更新日期：2014-01-01 00:00:00

abstract：:Conventional interferometers usually utilize beam splitters for wave splitting and recombination. These interferometers are widely used for precision measurement. Their sensitivity for phase measurement is limited by the shot noise, which can be suppressed with squeezed states of light. Here we study a new type of int...

journal_title：Nature communications

authors： Hudelist F,Kong J,Liu C,Jing J,Ou ZY,Zhang W

更新日期：2014-01-01 00:00:00

abstract：:Ions are ubiquitous biological regulators playing a key role for vital processes in animals and plants. The combined detection of ion concentration and real-time monitoring of small variations with respect to the resting conditions is a multiscale functionality providing important information on health states. This mu...

journal_title：Nature communications

authors： Romele P,Gkoupidenis P,Koutsouras DA,Lieberth K,Kovács-Vajna ZM,Blom PWM,Torricelli F

更新日期：2020-07-27 00:00:00

abstract：:The gut-derived orexigenic peptide hormone ghrelin enhances neuronal firing in the substantia nigra pars compacta, where dopaminergic neurons modulate the function of the nigrostriatal system for motor coordination. Here we describe a novel mechanism by which ghrelin enhances firing of nigral dopaminergic neurons by i...

journal_title：Nature communications

authors： Shi L,Bian X,Qu Z,Ma Z,Zhou Y,Wang K,Jiang H,Xie J

更新日期：2013-01-01 00:00:00

abstract：:The control of water-intake behavior is critical for life because an excessive water intake induces pathological conditions, such as hyponatremia or water intoxication. However, the brain mechanisms controlling water intake currently remain unclear. We previously reported that thirst-driving neurons (water neurons) in...

journal_title：Nature communications

authors： Matsuda T,Hiyama TY,Kobayashi K,Kobayashi K,Noda M

更新日期：2020-11-10 00:00:00

abstract：:Flicker or 1/f noise in metal-oxide-semiconductor field-effect transistors (MOSFETs) has been identified as the main source of noise at low frequency. It often originates from an ensemble of a huge number of charges becoming trapped and de-trapped. However, as a deviation from the well-known model of 1/f noise is obse...

journal_title：Nature communications

authors： Clément N,Nishiguchi K,Fujiwara A,Vuillaume D

更新日期：2010-10-19 00:00:00

abstract：:Helitrons are eukaryotic DNA transposons that have profoundly affected genome variability via capture and mobilization of host genomic sequences. Defining their mode of action is therefore important for understanding how genome landscapes evolve. Sequence similarities with certain prokaryotic mobile elements suggest a...

journal_title：Nature communications

authors： Grabundzija I,Hickman AB,Dyda F

更新日期：2018-03-29 00:00:00

abstract：:MicroRNAs (miRNAs) are critical to somatic cell reprogramming into induced pluripotent stem cells (iPSCs), however, exactly how miRNA expression changes support the transition to pluripotency requires further investigation. Here we use a murine secondary reprogramming system to sample cellular trajectories towards iPS...

journal_title：Nature communications

authors： Clancy JL,Patel HR,Hussein SM,Tonge PD,Cloonan N,Corso AJ,Li M,Lee DS,Shin JY,Wong JJ,Bailey CG,Benevento M,Munoz J,Chuah A,Wood D,Rasko JE,Heck AJ,Grimmond SM,Rogers IM,Seo JS,Wells CA,Puri MC,Nagy A,Preiss

更新日期：2014-12-10 00:00:00

abstract：:Repeated cell divisions and aging impair stem cell function. However, the mechanisms by which this occurs are not fully understood. Here we show that protection of telomeres 1A (Pot1a), a component of the Shelterin complex that protects telomeres, improves haematopoietic stem cell (HSC) activity during aging. Pot1a is...

journal_title：Nature communications

authors： Hosokawa K,MacArthur BD,Ikushima YM,Toyama H,Masuhiro Y,Hanazawa S,Suda T,Arai F

更新日期：2017-10-06 00:00:00