Abstract：
:The yeast Saccharomyces cerevisiae has been an essential component of human civilization because of its long global history of use in food and beverage fermentation. However, the diversity and evolutionary history of the domesticated populations of the yeast remain elusive. We show here that China/Far East Asia is likely the center of origin of the domesticated populations of the species. The domesticated populations form two major groups associated with solid- and liquid-state fermentation and appear to have originated from heterozygous ancestors, which were likely formed by outcrossing between diverse wild isolates primitively for adaptation to maltose-rich niches. We found consistent gene expansion and contraction in the whole domesticated population, as well as lineage-specific genome variations leading to adaptation to different environments. We show a nearly panoramic view of the diversity and life history of S. cerevisiae and provide new insights into the origin and evolution of the species.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Duan SF,Han PJ,Wang QM,Liu WQ,Shi JY,Li K,Zhang XL,Bai FYdoi
10.1038/s41467-018-05106-7subject
Has Abstractpub_date
2018-07-12 00:00:00pages
2690issue
1issn
2041-1723pii
10.1038/s41467-018-05106-7journal_volume
9pub_type
杂志文章abstract：:Reliable quantum information processing in the face of errors is a major fundamental and technological challenge. Quantum error correction protects quantum states by encoding a logical quantum bit (qubit) in multiple physical qubits. To be compatible with universal fault-tolerant computations, it is essential that sta...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms11526
更新日期：2016-05-05 00:00:00
abstract：:Hybrid halide perovskite solar cells were first demonstrated in 2009 with cell efficiency quickly soaring from below 10% to more than 23% in a few years. Halide perovskites have the desirable processing simplicity but are very fragile when exposed to water and heat. This fragility represents a great challenge for the ...
journal_title：Nature communications
pub_type： 杂志文章,评审
doi：10.1038/s41467-018-07382-9
更新日期：2018-11-28 00:00:00
abstract：:Substance abuse disorders are linked to alteration of circadian rhythms, although the molecular and neuronal pathways implicated have not been fully elucidated. Addictive drugs, such as cocaine, induce a rapid increase of dopamine levels in the brain. Here, we show that acute administration of cocaine triggers reprogr...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-18200-6
更新日期：2020-09-07 00:00:00
abstract：:The experimental investigation of quantum devices incorporating mechanical resonators has opened up new frontiers in the study of quantum mechanics at a macroscopic level. It has recently been shown that surface acoustic waves (SAWs) can be piezoelectrically coupled to superconducting qubits, and confined in high-qual...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-017-01063-9
更新日期：2017-10-17 00:00:00
abstract：:New microbial genomes are constantly being sequenced, and it is crucial to accurately determine their taxonomic identities and evolutionary relationships. Here we report PhyloPhlAn, a new method to assign microbial phylogeny and putative taxonomy using >400 proteins optimized from among 3,737 genomes. This method meas...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms3304
更新日期：2013-01-01 00:00:00
abstract：:Transcription activator-like effectors (TALEs) are important Xanthomonas virulence factors that bind DNA via a unique tandem 34-amino-acid repeat domain to induce expression of plant genes. So far, TALE repeats are described to bind as a consecutive array to a consecutive DNA sequence, in which each repeat independent...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms4447
更新日期：2014-03-11 00:00:00
abstract：:Nuclear factor-κB (NFκB) and peroxisome proliferator activated receptor-γ (PPARγ) are both transcription factors that perform distinct but overlapping roles in cellular regulation. Here we report that PPARγ acts as an E3 ubiquitin ligase, physically interacting with p65 to induce its ubiquitination and degradation. Th...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms2270
更新日期：2012-01-01 00:00:00
abstract：:Understanding human cooperation is of major interest across the natural and social sciences. But it is unclear to what extent cooperation is actually a general concept. Most research on cooperation has implicitly assumed that a person's behaviour in one cooperative context is related to their behaviour in other settin...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms5939
更新日期：2014-09-16 00:00:00
abstract：:Post-transcriptional regulation of cellular mRNA is essential for protein synthesis. Here we describe the importance of mRNA translational repression and mRNA subcellular location for protein expression during B lymphocyte activation and the DNA damage response. Cytoplasmic RNA granules are formed upon cell activation...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-017-00454-2
更新日期：2017-09-13 00:00:00
abstract：:Amplitude modes arising from symmetry breaking in materials are of broad interest in condensed matter physics. These modes reflect an oscillation in the amplitude of a complex order parameter, yet are typically unstable and decay into oscillations of the order parameter's phase. This renders stable amplitude modes rar...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-04601-1
更新日期：2018-06-05 00:00:00
abstract：:Our memories enable us to form expectations for our future experiences, yet the precise neural mechanisms underlying how we compare any experience to our memory remain unknown. Here, using intracranial EEG recordings, we show that episodic memories formed after a single visual experience establish expectations for fut...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-19828-0
更新日期：2020-11-27 00:00:00
abstract：:The recently discovered histone post-translational modification crotonylation connects cellular metabolism to gene regulation. Its regulation and tissue-specific functions are poorly understood. We characterize histone crotonylation in intestinal epithelia and find that histone H3 crotonylation at lysine 18 is a surpr...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-017-02651-5
更新日期：2018-01-09 00:00:00
abstract：:Two-dimensional materials provide extraordinary opportunities for exploring phenomena arising in atomically thin crystals. Beginning with the first isolation of graphene, mechanical exfoliation has been a key to provide high-quality two-dimensional materials, but despite improvements it is still limited in yield, late...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-16266-w
更新日期：2020-05-15 00:00:00
abstract：:Imaging compound action potentials (CAPs) in peripheral nerves could help avoid side effects in neuromodulation by selective stimulation of identified fascicles. Existing methods have low resolution, limited imaging depth, or are invasive. Fast neural electrical impedance tomography (EIT) allows fascicular CAP imaging...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-20127-x
更新日期：2020-12-07 00:00:00
abstract：:Osteoporosis is a devastating disease with an essential genetic component. GWAS have discovered genetic signals robustly associated with bone mineral density (BMD), but not the precise localization of effector genes. Here, we carry out physical and direct variant to gene mapping in human mesenchymal progenitor cell-de...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-09302-x
更新日期：2019-03-19 00:00:00
abstract：:Inorganic polyphosphate is known to be present in the mammalian brain at micromolar concentrations. Here we show that polyphosphate may act as a gliotransmitter, mediating communication between astrocytes. It is released by astrocytes in a calcium-dependent manner and signals to neighbouring astrocytes through P2Y(1) ...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms2364
更新日期：2013-01-01 00:00:00
abstract：:While plasmonic designs have dominated recent trends in structural color, schemes using localized surface plasmon resonances and surface plasmon polaritons that simultaneously achieve high color vibrancy at ultrahigh resolution have been elusive because of tradeoffs between size and performance. Herein we demonstrate ...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-12689-2
更新日期：2019-10-21 00:00:00
abstract：:Despite the clinical success of Androgen Receptor (AR)-targeted therapies, reactivation of AR signalling remains the main driver of castration-resistant prostate cancer (CRPC) progression. In this study, we perform a comprehensive unbiased characterisation of LNCaP cells chronically exposed to multiple AR inhibitors (...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-16126-7
更新日期：2020-05-19 00:00:00
abstract：:Bcl9 and Pygo are Wnt enhanceosome components that effect β-catenin-dependent transcription. Whether they mediate β-catenin-dependent neoplasia is unclear. Here we assess their roles in intestinal tumourigenesis initiated by Apc loss-of-function (ApcMin), or by Apc1322T encoding a partially-functional Apc truncation c...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-08164-z
更新日期：2019-02-13 00:00:00
abstract：:A central paradigm in conservation biology is that population bottlenecks reduce genetic diversity and population viability. In an era of biodiversity loss and climate change, understanding the determinants and consequences of bottlenecks is therefore an important challenge. However, as most studies focus on single sp...
journal_title：Nature communications
pub_type： 历史文章,杂志文章
doi：10.1038/s41467-018-06695-z
更新日期：2018-11-16 00:00:00
abstract：:Tropical carbon emissions are largely derived from direct forest clearing processes. Yet, emissions from drought-induced forest fires are, usually, not included in national-level carbon emission inventories. Here we examine Brazilian Amazon drought impacts on fire incidence and associated forest fire carbon emissions ...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-017-02771-y
更新日期：2018-02-13 00:00:00
abstract：:Monolayer chalcogenide semiconductors with both luminescent and ferromagnetic properties are dreamed for simultaneous polarization and detection of the valley degree of freedom in valleytronics. However, a conventional chalcogenide monolayer lacks these coexisting properties due to their mutually exclusive origins. He...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-09531-0
更新日期：2019-04-05 00:00:00
abstract：:Antibody cocktails represent a promising approach to prevent SARS-CoV-2 escape. The determinants for selecting antibody combinations and the mechanism that antibody cocktails prevent viral escape remain unclear. We compared the critical residues in the receptor-binding domain (RBD) used by multiple neutralizing antibo...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-20789-7
更新日期：2021-01-20 00:00:00
abstract：:Electroreduction of carbon dioxide into higher-energy liquid fuels and chemicals is a promising but challenging renewable energy conversion technology. Among the electrocatalysts screened so far for carbon dioxide reduction, which includes metals, alloys, organometallics, layered materials and carbon nanostructures, o...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms13869
更新日期：2016-12-13 00:00:00
abstract：:In adult skin epidermis and the epithelium lining the esophagus cells are constantly shed from the tissue surface and replaced by cell division. Tracking genetically labelled cells in transgenic mice has given insight into cell behavior, but conflicting models appear consistent with the results. Here, we use an additi...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-15258-0
更新日期：2020-03-18 00:00:00
abstract：:Deep subwavelength features are expected to have minimal impact on wave transport. Here we show that in contrast to this common understanding, disorder can have a dramatic effect in a one-dimensional disordered optical system with spatial features a thousand times smaller than the wavelength. We examine a unique regim...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms12927
更新日期：2016-10-06 00:00:00
abstract：:Understanding human mobility is crucial for applications such as forecasting epidemic spreading, planning transport infrastructure and urbanism in general. While, traditionally, mobility information has been collected via surveys, the pervasive adoption of mobile technologies has brought a wealth of (real time) data. ...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-11841-2
更新日期：2019-08-29 00:00:00
abstract：:Stability is now a critical factor in the commercialization of organic photovoltaic (OPV) devices. Both extrinsic stability to oxygen and water and intrinsic stability to light and heat in inert conditions must be achieved. Triplet states are known to be problematic in both cases, leading to singlet oxygen production ...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-20601-6
更新日期：2021-01-20 00:00:00
abstract：:Submarine channels are ubiquitous on the seafloor and their inception and evolution is a result of dynamic interaction between turbidity currents and the evolving seafloor. However, the morphodynamic links between channel inception and flow dynamics have not yet been monitored in experiments and only in one instance o...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms10886
更新日期：2016-03-21 00:00:00
abstract：:Ecosystems are composed of complex networks of many species interacting in different ways. While ecologists have long studied food webs of feeding interactions, recent studies increasingly focus on mutualistic networks including plants that exchange food for reproductive services provided by animals such as pollinator...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-15688-w
更新日期：2020-05-01 00:00:00
