Chronic treatment with classical and atypical antipsychotic drugs differentially decreases dopamine release in striatum and nucleus accumbens in vivo.

abstract：:In order to clarify the mechanism of action of cerulenin analog, C75, known to suppress feeding behavior, food intake was measured in adult CD-1 male mice n=5 per group, treated i.p. with 10 and 20mg/kg of C75. Animals in both treatment groups had significantly lower 24h food consumption rate relative to the control g...

journal_title：Neuroscience letters

authors： Binienda ZK,Ross IA,Gough B,Riccio T,Kim CS,Ali SF

更新日期：2010-01-29 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP) immunoreactive afferent nerves were seen intrarenally by prenatal day 16. They grow rapidly and CGRP positive nerves are observed at birth associated with the arterial and venous vascular tree, forming a rich plexus in the pelvic region and in the connective tissue located near t...

journal_title：Neuroscience letters

authors： Barajas L,Liu L,Nishiyama C

更新日期：1991-12-09 00:00:00

abstract：:Suicide is a major contributor to the morbidity and mortality of schizophrenia, accounting for approximately 10% of deaths in these patients. Genetic factors have been reported to modulate the risk for suicide, although the precise mechanism and magnitude of the genetic contribution are unknown. Further, suicide attem...

journal_title：Neuroscience letters

authors： Souza RP,De Luca V,Manchia M,Kennedy JL

更新日期：2011-02-11 00:00:00

abstract：:A procedure for dissociating viable taste cells from the rodent tongue was described. After the tongue was excised, the foliate and circumvallate papillae from the posterior region were blocked to small pieces and incubated for 2-3 h in a calcium-free salt solution containing the enzyme papain. The pieces were then tr...

journal_title：Neuroscience letters

authors： Herness MS

更新日期：1989-11-20 00:00:00

abstract：:Following the i.c.v. administration of antivasopressin serum the alpha-MPT-induced disappearance of noradrenaline was decreased in the dorsal septal nucleus, parafascicular nucleus and the rostral part of the nucleus tractus solitarii, whereas that of dopamine was lowered in the caudate nucleus and in the A2 region of...

journal_title：Neuroscience letters

authors： Versteeg DH,De Kloet ER,Greidanus TV,De Wied D

更新日期：1979-01-01 00:00:00

abstract：:A peptide consisting of residues 25-35 of the amyloid beta protein was applied to single neurons while monitoring membrane current by whole cell voltage clamp recording. Within minutes of direct exposure of a neuron to the amyloid beta peptide, a paroxysmal increase in neuronal membrane conductance was observed. This ...

journal_title：Neuroscience letters

authors： Simmons MA,Schneider CR

更新日期：1993-02-19 00:00:00

abstract：:A comparison of the effect of fatigue caused by electrical induction or voluntary contraction on Ia inhibition in human soleus muscle was investigated in fourteen healthy male subjects. The Hoffmann reflex (H reflex) was employed to elucidate the contribution of fatigue induced contraction to the Ia inhibition. A stat...

journal_title：Neuroscience letters

authors： Tsuboi T,Sato T,Egawa K,Miyazaki M

更新日期：1995-09-01 00:00:00

abstract：:We are constantly exposed to symbols such as traffic signs, emoticons in internet communication, or other abstract representations of objects as well as, of course, the written words. However, aside from the word reading, little is known about the way our brain responds when we read non-lexical iconic symbols. By usin...

journal_title：Neuroscience letters

authors： Shin YW,Kwon JS,Kwon KW,Gu BM,Song IC,Na DG,Park S

更新日期：2008-05-16 00:00:00

abstract：:GABAergic modulation of enkephalin, substance P and glutamic acid decarboxylase (GAD67) gene expression and the alterations induced by dopamine receptor blockade were studied in the rat striatum. Following subchronic treatment with the GABA-A agonist muscimol, the GABA-B agonist baclofen or the GABA transaminase inhib...

journal_title：Neuroscience letters

authors： Jolkkonen J,Jenner P,Marsden CD

更新日期：1994-10-24 00:00:00

abstract：:The 22Na+ efflux stimulated by selected agonists of the 4 excitatory amino acid receptors, previously detected in the striatum, has been studied on 22Na+-preloaded slices prepared from 10 major areas of the rat brain. All brain areas were found to be sensitive, albeit to varying extents, to excitatory amino acids. The...

journal_title：Neuroscience letters

authors： Luini A,Goldberg O,Teichberg VI

更新日期：1983-11-11 00:00:00

abstract：:Neuromuscular electrical stimulation (NMES) increases the excitability of corticospinal (CS) pathways by altering circuits in motor cortex (M1). How NMES affects circuits interposed between the ascending afferent volley and descending CS pathways is not known. Presently, we hypothesized that short-latency afferent inh...

journal_title：Neuroscience letters

authors： Mang CS,Bergquist AJ,Roshko SM,Collins DF

更新日期：2012-10-31 00:00:00

abstract：:The sexual differences and the seasonal variation in the vasoactive intestinal peptide (VIP) content of the suprachiasmatic nucleus (SCN) of a desert rodent, the jerboa (Jaculus orientalis) were studied using immunocytochemical techniques. During the period of sexual activity (spring-early summer), the VIP immunoreact...

journal_title：Neuroscience letters

authors： Lakhdar-Ghazal N,Kalsbeek A,Pevet P

更新日期：1992-09-14 00:00:00

abstract：:In the present study, we examined the localizations of canonical transient receptor potential channels (TRPCs) in rat basal ganglia. The dot-like staining pattern of TRPC5 was observed through the globus pallidus (GP) and caudate-putamen. TRPC7 had a strikingly high level of expression in the neuropil in the GP. In th...

journal_title：Neuroscience letters

authors： Chung YH,Kim D,Moon NJ,Oh CS,Lee E,Shin DH,Kim SS,Lee WB,Lee JY,Cha CI

更新日期：2007-07-05 00:00:00

abstract：:The brains of 7 dogs aged 6 to 18 years have been histochemically and immunohistochemically investigated at the light- and electron microscopy levels for preamyloid deposits and amyloid fibrils to verify the hypothesis that the accumulation of cleavage products of amyloid precursor protein is related not only to Alzhe...

journal_title：Neuroscience letters

authors： Giaccone G,Verga L,Finazzi M,Pollo B,Tagliavini F,Frangione B,Bugiani O

更新日期：1990-07-03 00:00:00

abstract：:Lesion-induced degeneration was combined with immunocytochemistry to study, with electron microscopy, the synaptic connectivity between corticothalamic axon terminals from the first and second somatosensory areas and local circuit neurons of the ipsilateral ventrobasal complex (VB), selectively labelled with an antibo...

journal_title：Neuroscience letters

authors： Barbaresi P,Manzoni T

更新日期：2003-03-27 00:00:00

abstract：:For several neurodegenerative disorders, including Parkinson's Disease (PD) and Alzheimer's Disease (AD), microRNAs (miRNAs) have been known to play a crucial role. So, in this study miR-132 and its role in PD cell models was investigated. We wanted to investigate the survival or death pathway involved in PD. We obser...

journal_title：Neuroscience letters

authors： Qazi TJ,Lu J,Duru L,Zhao J,Qing H

更新日期：2021-01-01 00:00:00

abstract：:The time-variant quadratic phase coupling (QPC) in trace alternant (TA) EEG patterns in healthy full-term neonates (quiet sleep) was investigated by means of time-variant bispectral analysis. The frequency plain 1-1.5 Hz <=> 3.5-4.5 Hz was used as the region-of-interest. QPC rhythms with a frequency of approximately 0...

journal_title：Neuroscience letters

authors： Schwab K,Putsche P,Eiselt M,Helbig M,Witte H

更新日期：2004-10-21 00:00:00

abstract：:Actions of the polyamines spermine and spermidine on NMDA-induced currents were examined in cultured hippocampal neurons from embryonic rat. In whole-cell patch experiments using voltage-clamp, spermine (300 microM) produced about a two-fold potentiation of responses to NMDA (at -70 mV in the presence of saturating gl...

journal_title：Neuroscience letters

authors： Araneda RC,Zukin RS,Bennett MV

更新日期：1993-04-02 00:00:00

abstract：:As the pre-dementia phase of Alzheimer disease, mild cognitive impairment (MCI) involves the onset and development of cognitive impairments. Opioid receptors play pivotal roles in the regulation of learning and cognition. Our study focused on the association of OPRK1 and OPRM1 methylation with MCI in Xinjiang Uygur an...

journal_title：Neuroscience letters

authors： Liu G,Ji H,Liu J,Xu C,Chang L,Cui W,Ye C,Hu H,Chen Y,Zhou X,Duan S,Wang Q

更新日期：2017-01-01 00:00:00

abstract：:Macrophage migration inhibitory factor (MIF) has been rediscovered as a hormone and immunomodulator as well as a proinflammatory cytokine. We investigated the expression of MIF protein and mRNA in the rat brain using optimized immunohistochemistry and in situ hybridization, respectively. By immunohistochemical analysi...

journal_title：Neuroscience letters

authors： Ogata A,Nishihira J,Suzuki T,Nagashima K,Tashiro K

更新日期：1998-05-01 00:00:00

abstract：:Several clinical and epidemiological studies suggest that Alzheimer's disease (AD) and vascular dementia share common risk factors. Oxidative stress is one of these well recognized factors. It can result from an excess of free-radical activity and impaired antioxidant defenses. Paraoxonase (PON1), a component of high ...

journal_title：Neuroscience letters

authors： Helbecque N,Cottel D,Codron V,Berr C,Amouyel P

更新日期：2004-03-18 00:00:00

abstract：:We have previously shown that glycine binding sites on presynaptic NMDA receptors (NMDA-Rs) can tonically regulate glutamate release in the rat visual cortex. In the present study, we investigated the subunit composition of these presynaptic NMDA-Rs. We recorded miniature a-amino-3-hydroxy-5-methyl-4-isoxazolepropioni...

journal_title：Neuroscience letters

authors： Li YH,Han TZ,Meng K

更新日期：2008-02-27 00:00:00

abstract：:Unilateral intraplantar injections (1/day for 3 days) of 4 mu g nerve growth factor (NGF) into the rat hindpaw increased the expression of prepro-tachykinin (PPT)- and prepro-calcitonin gene-related peptide (ppCGRP)-mRNA in bilateral L5 dorsal root ganglia (DRGs). This was accompanied by an increase of CGRP-like immun...

journal_title：Neuroscience letters

authors： Amann R,Sirinathsinghji DJ,Donnerer J,Liebmann I,Schuligoi R

更新日期：1996-01-26 00:00:00

abstract：:Electrical stimulation of the A1 noradrenergic region of the ventrolateral medulla produced synatic excitation (n = 19, 9%), inhibition (n = 5, 2%) or no effect (n = 184, 89%) in the activity of a total of 208 neurons in the subfornical organ (SFO) in male rats under urethane anesthesia. Almost all (n = 18) of the exc...

journal_title：Neuroscience letters

authors： Tanaka J,Mashiko N,Kawakami A,Hatakenaka S,Fujisawa S,Nomura M

更新日期：2002-10-25 00:00:00

abstract：:The roles played by glycine- and glutamate-mediated synaptic transmission in the generation of 5-hydroxytryptamine (5-HT)-induced rhythmic activity were examined in isolated spinal cord preparations from fetal rats. Bath application of 5-HT (0.1-30 microM) evoked rhythmic activity in lumbar ventral roots at and after ...

journal_title：Neuroscience letters

authors： Nakayama K,Nishimaru H,Kudo N

更新日期：2001-07-06 00:00:00

abstract：:The specific mRNA of myelin basic protein (MBP) was isolated from active myelinating rat brains. The isolated mRNA was able to direct the synthesis of immunochemically detectable MBP in a wheat-germ cell free protein synthesis system. There was, however, no evidence of neuronal translational control of the in vitro MB...

journal_title：Neuroscience letters

authors： Fan K

更新日期：1982-03-17 00:00:00

abstract：:Glucose metabolism produces lactate and hydrogen ions in an anaerobic environment. Cerebral ischemia or hypoxia is believed to become progressively lactacidemic. Monocarboxylate transporters (MCTs) in endothelial cells are essential for the transport of lactate from the blood into the brain. In addition, it is conside...

journal_title：Neuroscience letters

authors： Murakami R,Chiba Y,Nishi N,Matsumoto K,Wakamatsu K,Yanase K,Uemura N,Nonaka W,Ueno M

更新日期：2021-01-10 00:00:00

abstract：:Three forms of stress-induced analgesia (electric shock, forced water-swim and novelty) were used to examine the nature of the endogenous antiopiate system. It was hypothesized that a role of the antiopiate system may be to regulate the extent of antinociception within varying environments. The antiopiate properties o...

journal_title：Neuroscience letters

authors： Galina ZH,Kastin AJ

更新日期：1988-02-03 00:00:00

abstract：:Loss of balance and increased fall risk is a common problem associated with aging. Changes in vestibular function occur with aging but the contribution of reduced vestibular otolith function to fall risk remains unknown. We examined a population of 151 healthy individuals (aged 21-93) for both balance (sway measures) ...

journal_title：Neuroscience letters

authors： Serrador JM,Lipsitz LA,Gopalakrishnan GS,Black FO,Wood SJ

更新日期：2009-11-06 00:00:00

abstract：:In order to reveal neurodegeneration elicited by reactive oxygen intermediates (ROI), neuronally differentiated cells from mouse embryonal carcinoma P19 cell line were exposed to hydrogen peroxide (H2O2). Enhanced protein-phosphorylation on tyrosine residues was detectable within 5 min of exposure to H2O2, and gradual...

journal_title：Neuroscience letters

authors： Ishihara I,Minami Y,Nishizaki T,Matsuoka T,Yamamura H

更新日期：2000-01-28 00:00:00