Parameter determination and transformation for the focusing of dielectric microspheres illuminated by optical needle.

abstract：:Focal adhesion kinase (FAK) is a 125 kDa protein recruited as a participant in focal adhesion dynamics and serves as a signaling scaffold for the assembly and subsequent maturation of focal contact. Identification of new FAK binding proteins could reveal potential signaling targets and contribute to further developmen...

journal_title：Scientific reports

authors： Nguyen BT,Pyun JC,Lee SG,Kang MJ

更新日期：2019-09-09 00:00:00

abstract：:Resin composites containing reinforcing inert glass fillers combined with bioactive glass (BG) can aid in the prevention of secondary caries, which is a major cause of failure of contemporary composite restorations. A series of previous studies on experimental resin composites filled with BG 45S5 has demonstrated that...

journal_title：Scientific reports

authors： Par M,Spanovic N,Tauböck TT,Attin T,Tarle Z

更新日期：2019-11-21 00:00:00

abstract：:Glioblastoma (GBM) is the most prevalent and lethal type of primary malignant brain tumour. Recent studies suggest that the discovery of human cytomegalovirus (HCMV)-encoded microRNAs (miRNAs) might play a role in the pathogenesis of diseases, including GBM. In this study, we aimed to analyse the expression and functi...

journal_title：Scientific reports

authors： Liang Q,Wang K,Wang B,Cai Q

更新日期：2017-03-17 00:00:00

abstract：:A new species of fossil conifer wood, Podocarpoxylon donghuaiense sp. nov., is described from the late Eocene of Nadu Formation in Baise Basin of the Guangxi Province, South China. This fossil wood is characterized by distinct growth rings, circular to oval tracheids in cross section, 1-2-seriate opposite pits on radi...

journal_title：Scientific reports

authors： Li L,Jin JH,Quan C,Oskolski AA

更新日期：2016-08-30 00:00:00

abstract：:Extraction of mouse spinal motor neurons from transgenic mouse embryos recapitulating some aspects of neurodegenerative diseases like amyotrophic lateral sclerosis has met with limited success. Furthermore, extraction and long-term culture of adult mouse spinal motor neurons and glia remain also challenging. We presen...

journal_title：Scientific reports

authors： Beaudet MJ,Yang Q,Cadau S,Blais M,Bellenfant S,Gros-Louis F,Berthod F

更新日期：2015-11-18 00:00:00

abstract：:Despite recent advances, the myocardial microstructure remains imperfectly understood. In particular, bundles of cardiomyocytes have been observed but their three-dimensional organisation remains debated and the associated mechanical consequences unknown. One of the major challenges remains to perform multiscale obser...

journal_title：Scientific reports

authors： Tueni N,Vizet J,Genet M,Pierangelo A,Allain JM

更新日期：2020-11-25 00:00:00

abstract：:The parasitic nematode Trichuris trichiura is a significant burden on public health in developing countries, and currently available drugs exhibit a poor cure rate. Worms live within a specialised tunnel of host intestinal epithelial cells and have anterior-ventral projections of the cuticle termed "cuticular inflatio...

journal_title：Scientific reports

authors： O'Sullivan JDB,Cruickshank SM,Starborg T,Withers PJ,Else KJ

更新日期：2020-04-03 00:00:00

abstract：:We propose a hybrid plasmonic device consisting of a planar dielectric waveguide covering a gold nanostripe array fabricated on a gold film and investigate its guiding properties at telecom wavelengths. The fundamental modes of a hybrid device and their dependence on the key geometric parameters are studied. A communi...

journal_title：Scientific reports

authors： Thomas PA,Auton GH,Kundys D,Grigorenko AN,Kravets VG

更新日期：2017-03-24 00:00:00

abstract：:Bone regeneration, following fracture, relies on autologous and allogenic bone grafts. However, majority of fracture population consists of older individuals with poor quality bone associated with loss and/or modification of matrix proteins critical for bone formation and mineralization. Allografts suffer from same li...

journal_title：Scientific reports

authors： Carvalho MS,Poundarik AA,Cabral JMS,da Silva CL,Vashishth D

更新日期：2018-09-26 00:00:00

abstract：:Generally confinement size is considered to determine the dimensionality of nanostructures. While the exciton Bohr radius is used as a criterion to define either weak or strong confinement in optical experiments, the binding energy of confined excitons is difficult to measure experimentally. One alternative is to use ...

journal_title：Scientific reports

authors： Kim H,Lee W,Park S,Kyhm K,Je K,Taylor RA,Nogues G,Dang LS,Song JD

更新日期：2017-01-05 00:00:00

abstract：:A pancreatic β-cell line MIN6 was previously established in our lab from an insulinoma developed in an IT6 transgenic mouse expressing the SV40 T antigen in β-cells. This cell line has been widely used for in vitro analysis of β-cell function, but tends to lose the mature β-cell features, including glucose-stimulated ...

journal_title：Scientific reports

authors： Miyazaki S,Tashiro F,Tsuchiya T,Sasaki K,Miyazaki JI

更新日期：2021-01-12 00:00:00

abstract：:Research on argillite as a possible host rock for nuclear waste disposal is still an open subject since many issues need to be clarified. In the Underground Research Laboratories constructed for this purpose, a damaged zone around the excavation has been systematically observed and characterized by the appearance of m...

journal_title：Scientific reports

authors： Zaoui A,Sekkal W

更新日期：2015-03-06 00:00:00

abstract：:Huntington's disease (HD) is a monogenetic neurodegenerative disorder that is caused by the expansion of a polyglutamine region within the huntingtin (HTT) protein, but there is still an incomplete understanding of the molecular mechanisms that drive pathology. Expression of the mutant form of HTT is a key aspect of d...

journal_title：Scientific reports

authors： Fodale V,Pintauro R,Daldin M,Altobelli R,Spiezia MC,Bisbocci M,Macdonald D,Bresciani A

更新日期：2020-12-17 00:00:00

abstract：:The combination of biomaterials and stem cells for clinical applications constitute a great challenge in bone tissue engineering. Hence, cellular networks derived from cells-biomaterials crosstalk have a profound influence on cell behaviour and communication, preceding proliferation and differentiation. The purpose of...

journal_title：Scientific reports

authors： Benjumeda Wijnhoven I,Vallejos R,Santibanez JF,Millán C,Vivanco JF

更新日期：2020-10-05 00:00:00

abstract：:We report that misfolded cytosolic proteins can be cleared from mammalian cells by directing them to endoplasmic reticulum (ER). NAT1 R64W and Parkin R42P are naturally occurring misfolded variants of cytosolic enzymes that acetylate arylamines and ubiquitinate proteins, respectively. We demonstrate that proteasome in...

journal_title：Scientific reports

authors： Liu F,Koepp DM,Walters KJ

更新日期：2015-07-14 00:00:00

abstract：:Osteopontin (OPN) is involved in cell proliferation, migration, inflammation, and tumor progression in various tissues. OPN induces stemness by interacting with CD44, but the functional relevance of OPN-mediated interferon (IFN) signaling and hepatitis C virus (HCV) replication in stem cell populations remains unclear...

journal_title：Scientific reports

authors： Shirasaki T,Honda M,Yamashita T,Nio K,Shimakami T,Shimizu R,Nakasyo S,Murai K,Shirasaki N,Okada H,Sakai Y,Sato T,Suzuki T,Yoshioka K,Kaneko S

更新日期：2018-09-03 00:00:00

abstract：:Microalgae are versatile organisms capable of converting CO2, H2O, and sunlight into fuel and chemicals for domestic and industrial consumption. Thus, genetic modifications of microalgae for enhancing photosynthetic productivity, and biomass and bio-products generation are crucial for both academic and industrial appl...

journal_title：Scientific reports

authors： Baek K,Kim DH,Jeong J,Sim SJ,Melis A,Kim JS,Jin E,Bae S

更新日期：2016-07-28 00:00:00

abstract：:Biocompatible surfaces hold key to a variety of biomedical problems that are directly related to the competition between host-tissue cell integration and bacterial colonisation. A saving solution to this is seen in the ability of cells to uniquely respond to physical cues on such surfaces thus prompting the search for...

journal_title：Scientific reports

authors： Diu T,Faruqui N,Sjöström T,Lamarre B,Jenkinson HF,Su B,Ryadnov MG

更新日期：2014-11-20 00:00:00

abstract：:Antitumor drug development based on the concept of intervening in the antioxidant system of cancer cells has been gaining increased interest. In this study, we propose a promising strategy for cancer treatment using modulation of oxidative stress by suppression of glutathione S-transferases (GSTs), a typical antioxida...

journal_title：Scientific reports

authors： Fujitani N,Yoneda A,Takahashi M,Takasawa A,Aoyama T,Miyazaki T

更新日期：2019-10-14 00:00:00

abstract：:Pot experiments were carried out to study the effects of rice straw (RS) and rice straw ash (RSA) on the growth of early rice and α-diversity of bacterial community in soils around rare earth mining areas of Xunwu and Xinfeng counties in South Jiangxi of China. The results showed that the exploitation of rare earth re...

journal_title：Scientific reports

authors： Jin S,Jin W,Dong C,Bai Y,Jin D,Hu Z,Huang Y

更新日期：2020-06-25 00:00:00

abstract：:The tick receptor for outer surface protein A (TROSPA) is the only identified factor involved in tick gut colonization by various Borrelia species. TROSPA is localized in the gut epithelium and can recognize and bind the outer surface bacterial protein OspA via an unknown mechanism. Based on earlier reports and our la...

journal_title：Scientific reports

authors： Urbanowicz A,Lewandowski D,Szpotkowski K,Figlerowicz M

更新日期：2016-04-26 00:00:00

abstract：:Prosthesis embodiment, the perception of a prosthesis as part of one's body, may be an important component of functional recovery for individuals with upper limb absence. This work determined whether embodiment differs between body-powered and myoelectric prosthesis users. In a sample of nine individuals with transrad...

journal_title：Scientific reports

authors： Engdahl SM,Meehan SK,Gates DH

更新日期：2020-09-22 00:00:00

abstract：:Age-related accumulation of ploidy changes is associated with decreased expression of genes controlling chromosome segregation and cohesin functions. To determine the consequences of whole chromosome instability (W-CIN) we down-regulated the spindle assembly checkpoint component BUB1 and the mitotic cohesin SMC1A, and...

journal_title：Scientific reports

authors： Andriani GA,Almeida VP,Faggioli F,Mauro M,Tsai WL,Santambrogio L,Maslov A,Gadina M,Campisi J,Vijg J,Montagna C

更新日期：2016-10-12 00:00:00

abstract：:Schizophrenia is one of the most prevalent psychiatric disorders with complex genetic etiology. Accumulating evidence suggests that energy metabolism and oxidative stress play important roles in the pathophysiology of schizophrenia. Dysfunction of mitochondrial respiratory chain and altered expression of complex I sub...

journal_title：Scientific reports

authors： Li X,Zhang W,Tang J,Tan L,Luo XJ,Chen X,Yao YG

更新日期：2015-06-08 00:00:00

abstract：:Post-glycosylphosphatidylinositol (GPI) attachment to proteins 3, also known as PGAP3 or PERLD1 (PER1-like domain-containing protein 1), participates in the lipid remodeling process of glycosylphosphatidylinositol (GPI) anchor proteins during post-translational modification. Functional defect in PERLD1 was previously ...

journal_title：Scientific reports

authors： Sio YY,Anantharaman R,Lee SQE,Matta SA,Ng YT,Chew FT

更新日期：2020-01-20 00:00:00

abstract：:Focusing on the chemical basis of dietary selection while investigating the nutritional ecology of animals helps understand their feeding biology. It is also important to consider food abundance/biomass while studying the mechanism of animal food selection. We studied leaf selection in two Bornean folivorous primates ...

journal_title：Scientific reports

authors： Matsuda I,Tuuga A,Bernard H,Sugau J,Hanya G

更新日期：2013-01-01 00:00:00

abstract：:Amyloid precursor protein (APP) intracellular domain (AICD) is a product of APP processing with transcriptional modulation activity, whose overexpression causes various Alzheimer's disease (AD)-related dysfunctions. Here we report that 1-(3',4'-dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid) (CHF50...

journal_title：Scientific reports

authors： Branca C,Sarnico I,Ruotolo R,Lanzillotta A,Viscomi AR,Benarese M,Porrini V,Lorenzini L,Calzà L,Imbimbo BP,Ottonello S,Pizzi M

更新日期：2014-04-09 00:00:00

abstract：:The potency of cellular immune responses strongly depends on T cell avidity to antigen. Yet, functional avidity measurements are rarely performed in patients, mainly due to the technical challenges of characterizing heterogeneous T cells. The mean functional T cell avidity can be determined by the IFN-γ Elispot assay,...

journal_title：Scientific reports

authors： Ioannidou K,Baumgaertner P,Gannon PO,Speiser MF,Allard M,Hebeisen M,Rufer N,Speiser DE

更新日期：2017-03-13 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Essaidi-Laziosi M,Geiser J,Huang S,Constant S,Kaiser L,Tapparel C

更新日期：2020-07-22 00:00:00

abstract：:Congenital reproductive tract anomalies could impair fertility. Female and male reproductive tracts are developed from Müllerian ducts and Wolffian ducts, respectively, involving initiation, elongation and differentiation. Genetic basis solely for distal reproductive tract development is largely unknown. Lhfpl2 (lipom...

journal_title：Scientific reports

authors： Zhao F,Zhou J,Li R,Dudley EA,Ye X

更新日期：2016-03-11 00:00:00