High yield extraction of pure spinal motor neurons, astrocytes and microglia from single embryo and adult mouse spinal cord.

abstract：:Hydrogen sulfide (H2S) signaling has been considered a key regulator of plant developmental processes and defenses. In this study, we demonstrate that high levels of H2S inhibit auxin transport and lead to alterations in root system development. H2S inhibits auxin transport by altering the polar subcellular distributi...

journal_title：Scientific reports

authors： Jia H,Hu Y,Fan T,Li J

更新日期：2015-02-05 00:00:00

abstract：:Osteoporosis (OP) is a multifactorial disease influenced by genetic factors in more than half of the cases. In spite of the efforts to clarify the relationship among genetic factors and susceptibility to develop OP, many genetic associations need to be further functionally validated. Besides, some limitations as the c...

journal_title：Scientific reports

authors： de Lima CAD,de Lima SC,Barbosa AD,Sandrin-Garcia P,de Barros Pita W,de Azevêdo Silva J,Crovella S

更新日期：2019-11-11 00:00:00

abstract：:HIV-associated disseminated TB (tuberculosis) has been under-recognised and poorly characterised. Blood culture is the gold-standard diagnostic test, but is expensive, slow, and may under-diagnose TB dissemination. In a cohort of hospitalised HIV patients, we aimed to report the prevalence of TB-blood-culture positivi...

journal_title：Scientific reports

authors： Kerkhoff AD,Barr DA,Schutz C,Burton R,Nicol MP,Lawn SD,Meintjes G

更新日期：2017-09-07 00:00:00

abstract：:Self-organization and pattern formation in network-organized systems emerges from the collective activation and interaction of many interconnected units. A striking feature of these non-equilibrium structures is that they are often localized and robust: only a small subset of the nodes, or cell assembly, is activated....

journal_title：Scientific reports

authors： Nicolaides C,Juanes R,Cueto-Felgueroso L

更新日期：2016-02-17 00:00:00

abstract：:In clinical diagnostics and pathogen detection, profiling of complex samples for low-level genotypes represents a significant challenge. Advances in speed, sensitivity, and extent of multiplexing of molecular pathogen detection assays are needed to improve patient care. We report the development of an integrated platf...

journal_title：Scientific reports

authors： Velez DO,Mack H,Jupe J,Hawker S,Kulkarni N,Hedayatnia B,Zhang Y,Lawrence S,Fraley SI

更新日期：2017-02-08 00:00:00

abstract：:Understanding the neural basis of poor impulse control in Internet addiction (IA) is important for understanding the neurobiological mechanisms of this syndrome. The current study investigated how neuronal pathways implicated in response inhibition were affected in IA using a Go-Stop paradigm and functional magnetic r...

journal_title：Scientific reports

authors： Li B,Friston KJ,Liu J,Liu Y,Zhang G,Cao F,Su L,Yao S,Lu H,Hu D

更新日期：2014-05-22 00:00:00

abstract：:In low-resource hospitals of central Africa, neurological disorders are frequent and etiologies very diverse. The difficulty to identify invasive bacterial infections in this setting results in major antibiotic overuse. Biomarkers such as C-reactive protein (CRP) and procalcitonin (PCT) may help discriminate these con...

journal_title：Scientific reports

authors： Bottieau E,Mukendi D,Kalo JL,Lutumba P,Barbé B,Ramadan K,Van Esbroeck M,Jacobs J,Yansouni CP,Chappuis F,Boelaert M,Winkler AS,Verdonck K

更新日期：2019-10-29 00:00:00

abstract：:Cellular membrane distortion invokes variations in cellular physiology. However, lack of an appropriate system to control the stress and facilitate molecular analyses has hampered progress of relevant studies. In this study, a microfluidic system that finely manipulates membrane distortion of Chlamydomonas reinhardtii...

journal_title：Scientific reports

authors： Min SK,Yoon GH,Joo JH,Sim SJ,Shin HS

更新日期：2014-04-14 00:00:00

abstract：:Anatase TiO2 nanoparticles with exposed {001} facets were synthesized from Ti powder via a sequential hydrothermal reaction process. At the first-step hydrothermal reaction, H-titanate nanowires were obtained in NaOH solution with Ti powder, and at second-step hydrothermal reaction, anatase TiO2 nanoparticles with exp...

journal_title：Scientific reports

authors： Chu L,Qin Z,Yang J,Li X

更新日期：2015-07-20 00:00:00

abstract：:Unexpectedly large ocean waves or 'rogues' are sometimes claimed to be the cause of damage to ships at sea and to offshore structures. While wind-driven wave models are capable of predicting the average characteristics of waves, the maximum height of rogues that may occur is yet unknown. Rogues form in the open ocean ...

journal_title：Scientific reports

authors： Donelan MA,Magnusson AK

更新日期：2017-03-08 00:00:00

abstract：:Rapid diagnostic tests (RDTs) have been developed to detect influenza A virus for the swift diagnosis and management of patients. However, despite the simplicity and convenience, the low sensitivity of RDTs remains a limitation for their use in point of care testing (POCT). In this study, we developed a rapid fluoresc...

journal_title：Scientific reports

authors： Yu ST,Thi Bui C,Kim DTH,V T Nguyen A,Thi Trinh TT,Yeo SJ

更新日期：2018-09-07 00:00:00

abstract：:Mesenchymal stem cells (MSCs) have various functions, making a significant contribution to tissue repair. On the other hand, the viability and function of MSCs are not lasting after an in vivo transplant, and the therapeutic effects of MSCs are limited. Although various chemical modification methods have been applied ...

journal_title：Scientific reports

authors： Takayama Y,Kusamori K,Hayashi M,Tanabe N,Matsuura S,Tsujimura M,Katsumi H,Sakane T,Nishikawa M,Yamamoto A

更新日期：2017-12-05 00:00:00

abstract：:Hypothalamic growth hormone-releasing hormone (GHRH) neurons orchestrate body growth/maturation and have been implicated in feeding responses and ageing. However, the electrical patterns that dictate GHRH neuron functions have remained elusive. Since the inhibitory neuropeptide somatostatin (SST) is considered to be a...

journal_title：Scientific reports

authors： Osterstock G,Mitutsova V,Barre A,Granier M,Fontanaud P,Chazalon M,Carmignac D,Robinson IC,Low MJ,Plesnila N,Hodson DJ,Mollard P,Méry PF

更新日期：2016-04-13 00:00:00

abstract：:PEA3 transcription factor subfamily is present in a variety of tissues with branching morphogenesis, and play a particularly significant role in neural circuit formation and specificity. Many target genes in axon guidance and cell-cell adhesion pathways have been identified for Pea3 transcription factor (but not for E...

journal_title：Scientific reports

authors： Kandemir B,Gulfidan G,Arga KY,Yilmaz B,Kurnaz IA

更新日期：2020-10-23 00:00:00

abstract：:The entire recrystallisation sequence and associated crystallographic texture evolution of Mg-0.8Zn-0.2Ca (wt.%) alloy was tracked using a quasi-in-situ electron backscatter diffraction (EBSD) method. Characteristic "Rare Earth" (RE) texture was formed, originating mainly from double twins and twinning-related shear b...

journal_title：Scientific reports

authors： Guan D,Liu X,Gao J,Ma L,Wynne BP,Rainforth WM

更新日期：2019-05-09 00:00:00

abstract：:This paper presents a study of noise in room-temperature THz radiometers that use THz-to-optical upconversion followed by optical detection of thermal radiation. Despite some undesired upconverted thermal noise, no noise is intrinsically introduced by efficient electro-optic modulation via a sum-frequency-generation p...

journal_title：Scientific reports

authors： Santamaría-Botello G,Popovic Z,Abdalmalak KA,Segovia-Vargas D,Brown ER,García Muñoz LE

更新日期：2020-06-10 00:00:00

abstract：:Native collagen is arranged in bundles of aligned fibrils to withstand in vivo mechanical loads. Reproducing such a process under in vitro conditions has not met with major success. Our approach has been to induce nanolinks, during the self-assembly process, leading to delayed rather than inhibited fibrillogenesis. Fo...

journal_title：Scientific reports

authors： Nidhin M,Vedhanayagam M,Sangeetha S,Kiran MS,Nazeer SS,Jayasree RS,Sreeram KJ,Nair BU

更新日期：2014-08-06 00:00:00

abstract：:The regulation of inflammatory responses by innate immune receptors is recognized as a crucial step in the development of atherosclerosis, although the precise molecular mechanisms remain to be elucidated. This study focused on illustrating the roles of dendritic cell-specific intercellular adhesion molecule-3-grabbin...

journal_title：Scientific reports

authors： Yang K,Liu X,Liu Y,Wang X,Cao L,Zhang X,Xu C,Shen W,Zhou T

更新日期：2017-06-12 00:00:00

abstract：:Tellurite (TeO32-) is a hazardous and toxic oxyanion for living organisms. However, several microorganisms can bioconvert TeO32- into the less toxic form of elemental tellurium (Te0). Here, Rhodococcus aetherivorans BCP1 resting (non-growing) cells showed the proficiency to produce tellurium-based nanoparticles (NPs) ...

journal_title：Scientific reports

authors： Presentato A,Piacenza E,Darbandi A,Anikovskiy M,Cappelletti M,Zannoni D,Turner RJ

更新日期：2018-03-02 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related mortality globally. Because most patients are diagnosed at advanced stages of the disease, multi-targeted tyrosine kinase inhibitor sorafenib is the only available drug to show limited effectiveness. Novel and effective therapies are unmet me...

journal_title：Scientific reports

authors： Wang J,Sun P,Chen Y,Yao H,Wang S

更新日期：2018-07-19 00:00:00

abstract：:Stable electroluminescence from micro-pixelated light-emitting diode (μLED) occurs when electrons and holes are continuously injected from external electrodes. Different from the general recognition, in this work, μLED works in an operation mode, namely, non-electrical contact and non-carrier injection mode, and can b...

journal_title：Scientific reports

authors： Wang K,Liu Y,Wu C,Li D,Lv S,Zhang Y,Zhou X,Guo T

更新日期：2020-05-15 00:00:00

abstract：:Loss of seed shattering has been regarded as a key step during crop domestication. Mutagenesis contributes to the development of novel crop cultivars with a desired seed-shattering habit in a relatively short period of time, but also to uncovering the genetic architecture of seed shattering. 'Minamiyutaka', a non-shat...

journal_title：Scientific reports

authors： Li F,Komatsu A,Ohtake M,Eun H,Shimizu A,Kato H

更新日期：2020-09-10 00:00:00

abstract：:Recreational boating is an increasing activity in coastal areas and its spatiotemporal overlap with key habitats of marine species pose a risk for negative noise impacts. Yet, recreational vessels are currently unaccounted for in vessel noise models using Automatic Identification System (AIS) data. Here we conduct a c...

journal_title：Scientific reports

authors： Hermannsen L,Mikkelsen L,Tougaard J,Beedholm K,Johnson M,Madsen PT

更新日期：2019-10-29 00:00:00

abstract：:Early detection of dementia in Parkinson disease is a prerequisite for preventive therapeutic approaches. Modified serpinA1 in cerebrospinal fluid (CSF) was suggested as an early biomarker for differentiation between Parkinson patients with (PDD) or without dementia (PD). Within this study we aimed to further explore ...

journal_title：Scientific reports

authors： Halbgebauer S,Nagl M,Klafki H,Haußmann U,Steinacker P,Oeckl P,Kassubek J,Pinkhardt E,Ludolph AC,Soininen H,Herukka SK,Wiltfang J,Otto M

更新日期：2016-05-17 00:00:00

abstract：:Plants perceive and respond to volatile signals in their environment. Herbivore-infested plants release volatile organic compounds (VOCs) which can initiate systemic defense reactions within the plant and contribute to plant-plant communication. Here, for Ipomoea batatas (sweet potato) leaves we show that among variou...

journal_title：Scientific reports

authors： Meents AK,Chen SP,Reichelt M,Lu HH,Bartram S,Yeh KW,Mithöfer A

更新日期：2019-11-22 00:00:00

abstract：:Therizinosaurian theropods evolved many highly specialized osteological features in association with their bulky proportions, which were unusual in the context of the generally gracile Theropoda. Here we report a new therizinosaur, Lingyuanosaurus sihedangensis gen. et sp. nov., based on a specimen recovered from the ...

journal_title：Scientific reports

authors： Yao X,Liao CC,Sullivan C,Xu X

更新日期：2019-03-22 00:00:00

abstract：:Invasive giant knotweed (Fallopia sachalinensis) is native to northeastern Asia. In Korea, F. sachalinensis is confined to two volcanic islands, Ullung and Dok islands, where it occurs as dodecaploids (2n = 132). We investigated the molecular variation in 104 accessions from 94 populations of F. sachalinensis and its ...

journal_title：Scientific reports

authors： Park CW,Bhandari GS,Won H,Park JH,Park DS

更新日期：2018-10-30 00:00:00

abstract：:Mutations in the TGFβR2 gene have been associated with a life threatening risk of aortic dissection but no arrhythmic death has been previously reported. Two young females carrying a TGFβR2 mutation, initially diagnosed as Marfan syndrome or Loeys Dietz syndrome, presented sudden death with autopsy ruling out dissecti...

journal_title：Scientific reports

authors： Extramiana F,Milleron O,Elbitar S,Uccellini A,Langeois M,Spentchian M,Delorme G,Arnoult F,Denjoy I,Bouleti C,Fressart V,Iserin F,Maison-Blanche P,Abifadel M,Leenhardt A,Boileau C,Jondeau G

更新日期：2018-08-29 00:00:00

abstract：:Diffraction gratings are an essential optical component of high-power, short-pulse lasers. The maximum output of high-power pulsed lasers is always determined by laser resistance of gratings and this resistance is strongly dependent on the local near electric field intensity in the grating structure. We presented a no...

journal_title：Scientific reports

authors： Chen J,Huang H,Zhang Y,Wang Y,Kong F,Wang Y,Jin Y,Chen P,Xu J,Shao J

更新日期：2018-03-27 00:00:00

abstract：:Rotator cuff tears are common and are associated with shoulder pain, disability, and dysfunction. Previous studies that have reported different arthroscopic techniques are controversial. A network meta-analysis with indirect and direct evidence was performed to compare the effectiveness of arthroscopic techniques for ...

journal_title：Scientific reports

authors： Xu B,Chen L,Zou J,Gu Y,Hao L,Peng K

更新日期：2019-03-11 00:00:00