Abstract：
:Understanding the neural basis of poor impulse control in Internet addiction (IA) is important for understanding the neurobiological mechanisms of this syndrome. The current study investigated how neuronal pathways implicated in response inhibition were affected in IA using a Go-Stop paradigm and functional magnetic resonance imaging (fMRI). Twenty-three control subjects aged 15.2±0.5 years (mean±S.D.) and eighteen IA subjects aged 15.1±1.4 years were studied. Effective connectivity within the response inhibition network was quantified using (stochastic) dynamic causal modeling (DCM). The results showed that the indirect frontal-basal ganglia pathway was engaged by response inhibition in healthy subjects. However, we did not detect any equivalent effective connectivity in the IA group. This suggests the IA subjects fail to recruit this pathway and inhibit unwanted actions. This study provides a clear link between Internet addiction as a behavioral disorder and aberrant connectivity in the response inhibition network.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Li B,Friston KJ,Liu J,Liu Y,Zhang G,Cao F,Su L,Yao S,Lu H,Hu Ddoi
10.1038/srep05027subject
Has Abstractpub_date
2014-05-22 00:00:00pages
5027issn
2045-2322pii
srep05027journal_volume
4pub_type
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