Abstract:
:Therizinosaurian theropods evolved many highly specialized osteological features in association with their bulky proportions, which were unusual in the context of the generally gracile Theropoda. Here we report a new therizinosaur, Lingyuanosaurus sihedangensis gen. et sp. nov., based on a specimen recovered from the Lower Cretaceous Jehol Group of Lingyuan, Liaoning Province, China, which displays a combination of plesiomorphic and derived features. Most notably, the specimen is characterized by posterior dorsal vertebrae with a complex and unusual laminar structure; an ilium with a highly dorsoventrally expanded preacetabular process showing only slight lateral flaring of the ventral margin, a strongly anterodorsally inclined iliac blade, a small postacetabular process with a strongly concave dorsal margin, and a relatively robust pubic peduncle with a posteroventrally facing distal articular surface; a straight and robust femur with a small lesser trochanter; and a tibia that is longer than the femur. Phylogenetic analysis places Lingyuanosaurus in an intermediate position within Therizinosauria, i.e., between the early-branching therizinosaurs such as Falcarius, Jianchangosaurus, and Beipiaosaurus and the late-branching ones such as Alxasaurus and Therizinosaurus. This new therizinosaur sheds additional light on the evolution of major therizinosaurian characteristics, including particularly the distinctive pelvic girdle and hindlimb morphology seen in this group.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Yao X,Liao CC,Sullivan C,Xu Xdoi
10.1038/s41598-019-41560-zsubject
Has Abstractpub_date
2019-03-22 00:00:00pages
5026issue
1issn
2045-2322pii
10.1038/s41598-019-41560-zjournal_volume
9pub_type
杂志文章abstract::This study investigates the immune responses induced by metal-filled single-walled carbon nanotubes (SWCNT) under in vitro, ex vivo and in vivo settings. Either empty amino-functionalized CNTs [SWCNT-NH2 (1)] or samarium chloride-filled amino-functionalized CNTs with [SmCl3@SWCNT-mAb (3)] or without [SmCl3@SWCNT-NH2 (...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42605
更新日期:2017-02-15 00:00:00
abstract::Systemic antioxidative status has been implicated in glaucoma pathogenesis. Additionally, corneal hysteresis (CH) may contribute to glaucoma progression. Here, we evaluated the relationship between biological antioxidant potential (BAP) and CH. This study included 103 patients with open-angle glaucoma (OAG). We used a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-57520-x
更新日期:2020-01-17 00:00:00
abstract::Boron carbide (B4C) coating on diamond particle is synthesized by heating diamond particles in a powder mix of H3BO3 and B in Ar atmosphere. The composition, bond state and coverage fraction of boron carbide coating on diamond particles are investigated. The boron carbide coating favors to grow on diamond (100) surfac...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-11142-y
更新日期:2017-09-06 00:00:00
abstract::The pathophysiological actions of fatty acids (FAs) on Alzheimer's disease (AD), which are possibly mediated by genomic effects, are widely known; however, their non-genomic actions remain elusive. The aim of this study was to investigate the non-genomic mechanism of extra-cellular palmitic acid (PA) regulating beta-a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-04175-w
更新日期:2017-06-28 00:00:00
abstract:ABSTARCT:Graphene has sparked extensive research interest for its excellent physical properties and its unique potential for application in absorption of electromagnetic waves. However, the processing of stable large-scale graphene and magnetic particles on a micrometer-thick conductive support is a formidable challeng...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-02639-7
更新日期:2017-05-24 00:00:00
abstract::Long-term daylight deprivation such as during the Antarctic winter has been shown to lead to delayed sleep timing and sleep fragmentation. We aimed at testing whether retinal sensitivity, sleep and circadian rest-activity will change during long-term daylight deprivation on two Antarctic bases (Concordia and Halley VI...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33450-7
更新日期:2018-11-01 00:00:00
abstract::Stream microbes that occur in the Mediterranean Basin have been shown to possess heightened sensitivity to intensified water stress attributed to climate change. Here, we investigate the effects of long-term drought (150 days), storms and rewetting (7 days) on the diversity and composition of archaea, bacteria and fun...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-49832-4
更新日期:2019-09-18 00:00:00
abstract::Nitrogen-doped graphene (N-graphene) has attractive properties that has been widely studied over the years. However, its possible formation process still remains unclear. Here, we propose a highly feasible formation mechanism of the graphitic-N doing in thermally treated graphene with ammonia by performing ab initio m...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23495
更新日期:2016-03-22 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-019-42491-5
更新日期:2019-05-03 00:00:00
abstract::In the aftermath of the financial crisis of 2007-2009, the growing body of literature on financial networks has widely documented the predictive power of topological characteristics (e.g., degree centrality measures) to explain the systemic impact or systemic exposure of financial institutions. This study shows that c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-74259-7
更新日期:2020-10-19 00:00:00
abstract::This report identifies mitochondrial DNA (mtDNA) as a target and active mediator that links low-level oxidative stress to inflammatory response in pulmonary epithelial cells. Extrusion of mtDNA into the bronchoalveolar lavage fluid occurs as an early event in mice subjected to cigarette smoke injury, concomitantly wit...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-19216-1
更新日期:2018-01-17 00:00:00
abstract::Cortical neural activities lead to changes in the cerebral blood flow (CBF), which involves astrocytic control of cerebrovascular tone. However, the manner in which astrocytic activity specifically leads to vasodilation or vasoconstriction is difficult to determine. Here, cortical astrocytes genetically expressing a l...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep11455
更新日期:2015-06-16 00:00:00
abstract::The renin-angiotensin system (RAS) plays a key role in the control of vasoconstriction as well as sodium and fluid retention mediated mainly by angiotensin (Ang) II acting at the AT1 receptor (AT1R). Ang-(1-7) is another RAS peptide, identified as the endogenous ligand of the Mas receptor and known to counterbalance m...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-12074-3
更新日期:2017-09-19 00:00:00
abstract::We collected data from Kailuan cohort study from 2006 to 2011 to examine whether short-term effects of ambient temperature on heart rate (HR) and blood pressure (BP) are non-linear or linear, and their potential modifying factors. The HR, BP and individual information, including basic characteristics, life style, soci...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep21003
更新日期:2016-02-15 00:00:00
abstract::Activities involving observation of wild organisms (e.g. wildlife watching, tidepooling) can provide recreational and learning opportunities, with biologically diverse animal assemblages expected to be more stimulating to humans. In turn, more diverse communities may enhance human interest and facilitate provisioning ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33155-x
更新日期:2018-10-15 00:00:00
abstract::This study compared effects of five hypoxia-inducible factor (HIF) prolyl hydroxylases (PHD) inhibitors on PC12 cells and primary rat neurons following oxygen-glucose deprivation (OGD). At 100 µM, the PHD inhibitors did not cause cytotoxicity and apoptosis. MTT activity was only significantly reduced by FG4592 or Baye...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58482-w
更新日期:2020-01-31 00:00:00
abstract::Sleep, in addition to its brain restorative processes, plays an important role in memory transfer from its temporary store in the hippocampus to the more permanent storage in the neocortex. Alzheimer's disease (AD) affects memory and sleep. The aim of this study was to explore disturbances in global and local synchron...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-41851-5
更新日期:2019-03-29 00:00:00
abstract::Ultra-high power (exceeding the self-focusing threshold by more than three orders of magnitude) light beams from ground-based laser systems may find applications in space-debris cleaning. The propagation of such powerful laser beams through the atmosphere reveals many novel interesting features compared to traditional...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep30697
更新日期:2016-08-02 00:00:00
abstract::The origin of the enantio- and regioselectivity of ring-opening reaction of oxabicyclic alkenes catalyzed by rhodium/Josiphos has been examined using M06-2X density functional theory(DFT). DFT calculations predict a 98% ee for the enantioselectivity and only the 1,2-trans product as one regio- and diastereomer, in exc...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40491
更新日期:2017-01-11 00:00:00
abstract::Mesenchymal stem cells (MSCs) are multi-potent cells that are self-renewable and possess the potential to differentiate into multiple lineages. Several studies demonstrated that MSCs could regulate a Th17/Treg balance and could be a potential therapeutic target for Rheumatoid Arthritis (RA). A20 is highly expressed in...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-18693-0
更新日期:2018-01-11 00:00:00
abstract::A cobalt sulfide/PVDF(Polyvinylidene Fluoride) composite was prepared by a simple blending method, and the microstructure of the composite was investigated through X-ray diffraction, scanning electron microscopy, and field emission scanning electron microscopy. Increased absorption properties at frequencies ranging fr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-47037-3
更新日期:2019-07-19 00:00:00
abstract::The potential of a spheroid tumor model composed of cells in different proliferative and metabolic states for the development of new anticancer strategies has been amply demonstrated. However, there is little or no information in the literature on the problems of reproducibility of data originating from experiments us...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep19103
更新日期:2016-01-11 00:00:00
abstract::Quantum key agreement is an important topic that the shared key must be negotiated equally by all participants, and any nontrivial subset of participants cannot fully determine the shared key. To date, the embed modes of subkey in all the previously proposed quantum key agreement protocols are based on either BB84 or ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep45046
更新日期:2017-03-23 00:00:00
abstract::It is well known that tumour-associated macrophages (TAMs) play an important role in tumour development by modulating the tumour microenvironment, and targeting of protumour activation or the M2 polarization of TAMs is expected to be an effective therapy for cancer patients. We previously demonstrated that onionin A (...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29588
更新日期:2016-07-12 00:00:00
abstract::Salivary duct carcinoma (SDC) is an uncommon, but aggressive malignant tumor with a high mortality rate. Herein, we reported the detection of somatic KRAS A146T and Q61H mutations in 2 out of 4 (50%) sarcomatoid SDC variants. Transgenic mice carrying the human oncogenic KRAS(G12V), which spatiotemporal activation by t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13347
更新日期:2015-08-20 00:00:00
abstract::Classical swine fever virus (CSFV) non-structural protein 3 (NS3) is a multifunctional non-structural protein that plays a major role in viral replication. However, how exactly NS3 exerts these functions remains unknown. Here, we identified tumour necrosis factor receptor-associated factor 6 (TRAF6) as a novel NS3-int...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06934-1
更新日期:2017-07-27 00:00:00
abstract::The unconventional myosin MYO18A that contains a PDZ domain is required for muscle integrity during zebrafish development. However, the mechanism by which it functions in myofibers is not clear. The presence of a PDZ domain suggests that MYO18A may interact with other partners to perform muscle-specific functions. Her...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep36768
更新日期:2016-11-08 00:00:00
abstract::Zooplankton provide the key link between primary production and higher levels of the marine food web and they play an important role in mediating carbon sequestration in the ocean. All commercially harvested fish species depend on zooplankton populations. However, spatio-temporal distributions of zooplankton are notor...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-37129-x
更新日期:2019-01-24 00:00:00
abstract::This research utilized an external longitudinal dataset of hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) to compare and validate various predictive models that support the current recommendations to select the most effective predictive risk models to estimate short- and long-term mortality and fa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33389
更新日期:2016-09-16 00:00:00
abstract::A biochemical reaction model clarifies for the first time how cold atmospheric plasmas (CAPs) affect mitochondrial redox homeostasis and energy metabolism. Fundamental mitochondrial functions in pyruvic acid oxidation, the tricarboxylic acid (TCA) cycle and oxidative phosphorylation involving the respiratory chain (RC...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-53219-w
更新日期:2019-11-20 00:00:00