Do nuclear-encoded core subunits of mitochondrial complex I confer genetic susceptibility to schizophrenia in Han Chinese populations?

abstract：:Chemical dissimilarity of tellurium oxide with silica glass increases phase separation and crystallization tendency when mixed and melted for making a glass. We report a novel technique for incorporating an Er(3+)-doped tellurite glass composition into silica substrates through a femtosecond (fs) laser generated plasm...

journal_title：Scientific reports

authors： Chandrappan J,Murray M,Kakkar T,Petrik P,Agocs E,Zolnai Z,Steenson DP,Jha A,Jose G

更新日期：2015-09-15 00:00:00

abstract：:ANCA vasculitis encompasses several autoimmune conditions characterised by destruction of small vessels, inflammation of the respiratory tract and glomerulonephritis. Most patients harbour autoantibodies to myeloperoxidase (MPO) or proteinase 3 (PR3). Clinical and experimental data suggest that pathogenesis is driven ...

journal_title：Scientific reports

authors： O'Brien EC,Abdulahad WH,Rutgers A,Huitema MG,O'Reilly VP,Coughlan AM,Harrington M,Heeringa P,Little MA,Hickey FB

更新日期：2015-07-07 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Zhang Y,Launay H,Schramm A,Lebrun R,Gontero B

更新日期：2018-08-29 00:00:00

abstract：:α-MnO2 nanotubes were fabricated using a hydrothermal technique. Li, Na and K ions were introduced into MnO2 nanotubes to tailor their magnetic properties. It was found that with a doping concentration lower than 12 at%, the nanotubes showed ferromagnetic-like ordering at low temperature (<50 K), while antiferromagnet...

journal_title：Scientific reports

authors： Tseng LT,Lu Y,Fan HM,Wang Y,Luo X,Liu T,Munroe P,Li S,Yi J

更新日期：2015-03-13 00:00:00

abstract：:The exploitation of surface plasmon polaritons has been mostly limited to the visible and near infrared range, due to the low frequency limit for coherent plasmon excitation and the reduction of confinement on the metal surface for lower energies. In this work we show that 3D--out of plane--nanostructures can consider...

journal_title：Scientific reports

authors： Malerba M,Alabastri A,Miele E,Zilio P,Patrini M,Bajoni D,Messina GC,Dipalo M,Toma A,Proietti Zaccaria R,De Angelis F

更新日期：2015-11-10 00:00:00

abstract：:Glucose homeostasis is regulated by insulin, which is produced in the β-cells of the pancreas. The synthesis of insulin is controlled by several transcription factors including PDX-1, USF1 and USF2. Both, PDX-1 and USF1 were identified as substrates for protein kinase CK2. Here, we have analysed the interplay of PDX-1...

journal_title：Scientific reports

authors： Spohrer S,Groß R,Nalbach L,Schwind L,Stumpf H,Menger MD,Ampofo E,Montenarh M,Götz C

更新日期：2017-11-27 00:00:00

abstract：:Glucocorticoid receptor (GR) is a hormone-activated transcription regulatory protein involved in metabolism as well as adrenocortical responses to psychosocial stress. Ligand-activated GR localizes to the nucleus, where GR homodimers regulate gene transcription via direct binding to glucocorticoid response elements (G...

journal_title：Scientific reports

authors： Oasa S,Mikuni S,Yamamoto J,Kurosaki T,Yamashita D,Kinjo M

更新日期：2018-05-10 00:00:00

abstract：:Functional DNA sub-sequences and genome elements are spatially clustered through the genome just as keywords in literary texts. Therefore, some of the methods for ranking words in texts can also be used to compare different DNA sub-sequences. In analogy with the literary texts, here we claim that the distribution of d...

journal_title：Scientific reports

authors： Moghaddasi H,Khalifeh K,Darooneh AH

更新日期：2017-01-27 00:00:00

abstract：:Coronaviruses may exert severely negative effects on the mortality and morbidity of birds and mammals including humans and domestic animals. Most recently CoVID-19 has killed about half million people (27th of June, 2020). Susceptibility to this disease appears to differ markedly across different societies but the fac...

journal_title：Scientific reports

authors： Jankowiak Ł,Rozsa L,Tryjanowski P,Møller AP

更新日期：2020-07-27 00:00:00

abstract：:Cross-polarization conversion plays an important role in visible light manipulation. Metasurface with asymmetric structure can be used to achieve polarization conversion of linearly polarized light. Based on this, we design a quasi-periodic dendritic metasurface model composed of asymmetric dendritic cells. The simula...

journal_title：Scientific reports

authors： Fang ZH,Chen H,An D,Luo CR,Zhao XP

更新日期：2018-06-26 00:00:00

abstract：:The Batrachosauroididae are an enigmatic group of salamanders known from the Cretaceous and Tertiary of North America and Europe. In Europe, the family is known only by two species of the genus Palaeoproteus. The genus has limited distribution in Western and Central Europe. In the present paper, we describe a new spec...

journal_title：Scientific reports

authors： Vasilyan D,Yanenko V

更新日期：2020-02-17 00:00:00

abstract：:Asymmetric cell divisions are required for cellular diversity and defects can lead to altered daughter cell fates and numbers. In a genetic screen for C. elegans mutants with defects in dopaminergic head neuron specification or differentiation, we isolated a new allele of the transcription factor HAM-1 [HSN (Hermaphro...

journal_title：Scientific reports

authors： Offenburger SL,Bensaddek D,Murillo AB,Lamond AI,Gartner A

更新日期：2017-06-28 00:00:00

abstract：:High Resolution Melt (HRM) is a versatile and rapid post-PCR DNA analysis technique primarily used to differentiate sequence variants among only a few short amplicons. We recently developed a one-vs-one support vector machine algorithm (OVO SVM) that enables the use of HRM for identifying numerous short amplicon seque...

journal_title：Scientific reports

authors： Fraley SI,Athamanolap P,Masek BJ,Hardick J,Carroll KC,Hsieh YH,Rothman RE,Gaydos CA,Wang TH,Yang S

更新日期：2016-01-18 00:00:00

abstract：:The aim of this study was to evaluate the impact of lymph node status from neck dissection pathological specimens on the survival for isolated regional nodal recurrence or persistence after primary treatment of nasopharyngeal carcinoma. Through a retrospective cohort study performed in an academic tertiary referral ho...

journal_title：Scientific reports

authors： Yeung DCM,Yeung Z,Wong EWY,Vlantis AC,Chan JYK

更新日期：2020-03-27 00:00:00

abstract：:The rectifying properties of α,ω-dithiol terminated oligo(phenylene ethynylene) molecules sandwiched between heterometallic electrodes, including the molecular length and side group effects, are theoretically investigated using the fully self-consistent nonequilibrium Green's function method combined with density func...

journal_title：Scientific reports

authors： Fu XX,Zhang RQ,Zhang GP,Li ZL

更新日期：2014-09-15 00:00:00

abstract：:GABAA receptor-mediated inhibition depends on the maintenance of low level intracellular [Cl-] concentration, which in adult depends on neuron specific K+-Cl- cotransporter-2 (KCC2). Previous studies have shown that KCC2 was downregulated in both epileptic patients and various epileptic animal models. However, the tem...

journal_title：Scientific reports

authors： Chen L,Wan L,Wu Z,Ren W,Huang Y,Qian B,Wang Y

更新日期：2017-03-13 00:00:00

abstract：:This corrects the article DOI: 10.1038/srep30212. ...

journal_title：Scientific reports

authors： Xu H,Chen X,Xu X,Shi R,Suo S,Cheng K,Zheng Z,Wang M,Wang L,Zhao Y,Tian B,Hua Y

更新日期：2017-05-26 00:00:00

abstract：:Phosphorylation plays important roles in several processes including synaptic plasticity and memory. The critical role of extracellular signal-regulated kinase (ERK) in these processes is well established. ERK is activated in a sustained manner by different stimuli. However, the mechanisms of sustained ERK activation ...

journal_title：Scientific reports

authors： Maharana C,Sharma KP,Sharma SK

更新日期：2013-01-01 00:00:00

abstract：:When realising future fusion reactors, their stationary burning must be maintained and the heat flux to the divertor must be reduced. This essentially requires a stationary internal transport barrier (ITB) plasma with a fast control system. However, the time scale for determining the position of the foot point of an I...

journal_title：Scientific reports

authors： Kenmochi N,Minami T,Mizuuchi T,Takahashi C,Weir GM,Nishioka K,Kobayashi S,Nakamura Y,Okada H,Kado S,Yamamoto S,Ohshima S,Konoshima S,Ohtani Y,Nagasaki K

更新日期：2020-01-08 00:00:00

abstract：:We present a combined experimental and theoretical study of the electronic properties of close-spaced dangling-bond (DB) pairs in a hydrogen-passivated Si(001):H p-doped surface. Two types of DB pairs are considered, called "cross" and "line" structures. Our scanning tunneling spectroscopy (STS) data show that, althou...

journal_title：Scientific reports

authors： Engelund M,Zuzak R,Godlewski S,Kolmer M,Frederiksen T,García-Lekue A,Sánchez-Portal D,Szymonski M

更新日期：2015-09-25 00:00:00

abstract：:Little is known about the relationship between soil microbial communities and soil properties in southern boreal forests. To further our knowledge about that relationship, we compared the soil samples in southern boreal forests of the Greater Khingan Mountains-the southernmost boreal forest biome in the world. The for...

journal_title：Scientific reports

authors： Vuong TM,Zeng JY,Man XL

更新日期：2020-12-16 00:00:00

abstract：:Targeting epigenetic reader proteins by small molecule inhibitors represents a new therapeutic concept in autoimmune diseases such as rheumatoid arthritis (RA). Although inhibitors targeting bromodomain protein 1 (BRD1) are in development, the function of BRD1 has hardly been studied. We investigated the therapeutic p...

journal_title：Scientific reports

authors： Klein K,Kato M,Frank-Bertoncelj M,Kolling C,Ciurea A,Gay S,Ospelt C

更新日期：2018-07-24 00:00:00

abstract：:Cytochrome P450 (CYP) 3A accounts for nearly 30% of the total CYP enzymes in the human liver and participates in the metabolism of over 50% of clinical drugs. Moreover, CYP3A plays an important role in chemical metabolism, toxicity, and carcinogenicity. New animal models are needed to investigate CYP3A functions, espe...

journal_title：Scientific reports

authors： Lu J,Shao Y,Qin X,Liu D,Chen A,Li D,Liu M,Wang X

更新日期：2017-02-20 00:00:00

abstract：:Gastroenterologists are still unable to differentiate between some of the most ordinary disorders of the gut and consequently patients are misdiagnosed. We have developed a swallowable gas sensor capsule for addressing this. The gases of the gut are the by-product of the fermentation processes during digestion, affect...

journal_title：Scientific reports

authors： Ou JZ,Cottrell JJ,Ha N,Pillai N,Yao CK,Berean KJ,Ward SA,Grando D,Muir JG,Harrison CJ,Wijesiriwardana U,Dunshea FR,Gibson PR,Kalantar-Zadeh K

更新日期：2016-09-16 00:00:00

abstract：:Recently, structural colour formation and light control by accumulated guanine crystals were reported. However, the relationship between light interference by guanine platelets and light intensity in an individual platelet must be examined further. This study presents experimental evidence that the guanine crystal pla...

journal_title：Scientific reports

authors： Iwasaka M,Asada H

更新日期：2018-11-19 00:00:00

abstract：:Vortices are essential to angular momentum in quantum systems such as ultracold atomic gases. The existence of quantized vorticity in bosonic systems stimulated the development of the Gross-Pitaevskii mean-field approximation. However, the true dynamics of angular momentum in finite, interacting many-body systems like...

journal_title：Scientific reports

authors： Weiner SE,Tsatsos MC,Cederbaum LS,Lode AU

更新日期：2017-01-16 00:00:00

abstract：:Previous studies on the associations between dietary antioxidant vitamins and the risk of cervical cancer remain inconsistent, and little evidence is available for serum antioxidant vitamins, which provide more accurate measurements of these nutrients. We conducted a case-control study of 458 incident cases with invas...

journal_title：Scientific reports

authors： Guo L,Zhu H,Lin C,Che J,Tian X,Han S,Zhao H,Zhu Y,Mao D

更新日期：2015-09-04 00:00:00

abstract：:Directional transport of auxin is essential for plant development, with PIN auxin transport proteins representing an integral part of the machinery that controls hormone distribution. However, unlike the rapidly emerging framework of molecular determinants regulating PIN protein abundance and subcellular localization,...

journal_title：Scientific reports

authors： Benjamins R,Barbez E,Ortbauer M,Terpstra I,Lucyshyn D,Moulinier-Anzola J,Khan MA,Leitner J,Malenica N,Butt H,Korbei B,Scheres B,Kleine-Vehn J,Luschnig C

更新日期：2016-08-24 00:00:00

abstract：:Danggui Buxue Tang (DBT) is a classic Chinese herbal formula which consists of Astragali mongholici Radix and Angelica sinensis Radix (ASR). For chemical ingredients, HPLC were performed. Results showed compared with single herbs, DBT decoction could promote the dissolution of ingredients such as ferulic acid and caly...

journal_title：Scientific reports

authors： Lin PL,Li ZC,Xie RF,Wang YH,Zhou X

更新日期：2017-03-22 00:00:00

abstract：:It is generally believed that anthropogenic aerosols cool the atmosphere; therefore, they offset the global warming resulting from greenhouse gases to some extent. Reduction in sulphate, a primary anthropogenic aerosol, is necessary for mitigating air pollution, which causes atmospheric warming. Here, the changes in t...

journal_title：Scientific reports

authors： Takemura T

更新日期：2020-12-10 00:00:00