Abstract：
OBJECTIVE:To assess the prevalence of obstructive sleep apnoea (OSA) in men presenting with erectile dysfunction (ED) at a single centre. PATIENTS AND METHODS:All men attending a specialised andrology outpatient department with a new diagnosis of ED were included in this prospective study. All patients completed three questionnaires: the International Index of Erectile Function (IIEF) and two sleep questionnaires [the Obstructive Sleep Apnoea Screening questionnaire and the Insomnia Severity Index (ISI)]. Their ED management was subsequently undertaken in accordance with local and European guidelines. An OSA diagnosis was made based on a score of ≥3 on the Obstructive Sleep Apnoea Screening questionnaire and those patients were referred for specialist management. RESULTS:Between February and September 2016, 129 patients with ED completed the study questionnaires. In all, 71 patients (55%) had a score of ≥3 on the Obstructive Sleep Apnoea Screening questionnaire, indicating a need for specialist sleep referral. Men who scored ≥3 on the Obstructive Sleep Apnoea Screening questionnaire were significantly older (61.4 vs 46.5 years; P < 0.001) and had a significantly higher body mass index (29.4 vs 26.7 kg/m2 ; P < 0.001) when compared to the control group (OSA score of <3). The sleep apnoea group (OSA score of ≥3) had significantly worse IIEF-ED scores (6.2 vs 9.1; P = 0.018) and ISI scores (7.9 vs 5.5; P = 0.061). CONCLUSION:Men presenting to the andrology clinic with ED are at significant risk of having undiagnosed sleep disorders. This has serious adverse health consequences, as well as being associated with potential dangers at work and travel. The patient compliance was high with 78% completing all three questionnaires. It is feasible to screen this population for sleep disturbance and this should be part of the ED assessment.
journal_name
BJU Intjournal_title
BJU internationalauthors
Kalejaiye O,Raheem AA,Moubasher A,Capece M,McNeillis S,Muneer A,Christopher AN,Garaffa G,Ralph DJdoi
10.1111/bju.13961subject
Has Abstractpub_date
2017-12-01 00:00:00pages
855-860issue
6eissn
1464-4096issn
1464-410Xjournal_volume
120pub_type
杂志文章abstract：:• To review the published data on predisposing risk factors for cancer treatment-induced haemorrhagic cystitis (HC) and the evidence for the different preventive and therapeutic measures that have been used in order to help clinicians optimally define and manage this potentially serious condition. • Despite recognitio...
journal_title：BJU international
pub_type： 杂志文章,评审
doi：10.1111/bju.12291
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abstract：OBJECTIVES:To determine the outcomes of complete surgical resection of T4 prostate cancer after inductive androgen-deprivation therapy (ADT), as inductive ADT and subsequent radical prostatectomy (RP) is not recommended by any guideline yet. PATIENTS AND METHODS:A monocentric RP database was queried for patients initi...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/bju.14393
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abstract：OBJECTIVE:To determine if the biochemical composition of a renal calculus can be measured from 'dust' obtained during laser fragmentation. PATIENTS AND METHODS:This pilot study was set in a tertiary referral hospital between 2011 and 2013. Stone dust was aspirated through the ureteroscope during lasering and a stone f...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/bju.13448
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abstract：OBJECTIVE:To investigate the validity of prostate-specific antigen (PSA) as a tumour marker in men with clinically localized prostate cancer who have selected watchful waiting, by determining if serial PSA level measurements are correlated with findings of malignancy or benign prostatic hyperplasia (BPH) at serial endo...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2006.06515.x
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVE:To determine the efficacy of fluoroquinolone prophylaxis in patients undergoing transrectal ultrasonography (TRUS)-guided biopsy of the prostate in the Norwich population, and its correlation with ciprofloxacin resistance in the faecal flora. We also aimed to determine the usefulness of a pre-biopsy rectal sc...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/bju.12865
更新日期：2015-07-01 00:00:00
abstract：OBJECTIVE:To address concerns about the impact of training on patient outcomes during the 'learning curve' for laparoscopic radical prostatectomy (LRP), we compare the results of our patients undergoing LRP with and without trainees performing a substantial proportion of the cases. PATIENTS AND METHODS:In all, 771 con...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2008.08262.x
更新日期：2009-05-01 00:00:00
abstract：OBJECTIVE:To investigate the detection rate and extent of high-grade prostatic intraepithelial neoplasia (HGPIN) and atypical glands (AG) suspicious for prostate cancer, and the cancer risk in subsequent biopsies, diagnosed by a first 24-core saturation biopsy, as although the optimum extent of biopsy is controversial ...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2006.06728.x
更新日期：2007-04-01 00:00:00
abstract：OBJECTIVE:To create an experimental animal model to examine changes in bladder volume and histology after bladder augmentation in growing individuals and from the model, evaluate a method using demucosalized intestinal grafts and short-term bladder drainage. MATERIALS AND METHODS:The study comprised 21 piglets: in gro...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.1999.00895.x
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abstract：OBJECTIVE:To validate high-sensitivity C-reactive protein (hs-CRP) serum levels as an independent marker for disease-free survival (DFS) in clinically localised clear cell renal cell carcinoma (ccRCC). PATIENTS AND METHODS:In all, 403 consecutive patients with clinically localised (T1-3N0M0) ccRCC treated by radical o...
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pub_type： 杂志文章
doi：10.1111/bju.12067
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journal_title：BJU international
pub_type： 杂志文章
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journal_title：BJU international
pub_type： 杂志文章
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journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2007.07198.x
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journal_title：BJU international
pub_type： 杂志文章
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journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2011.10868.x
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pub_type： 杂志文章
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journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.1999.00268.x
更新日期：1999-11-01 00:00:00
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journal_title：BJU international
pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1111/j.1464-410X.2007.07151.x
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pub_type： 杂志文章
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更新日期：2009-03-01 00:00:00
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pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期：2007-11-01 00:00:00
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journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2008.07829.x
更新日期：2008-11-01 00:00:00
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pub_type： 杂志文章,meta分析,评审
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更新日期：2013-12-01 00:00:00
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journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2005.05851.x
更新日期：2005-12-01 00:00:00
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pub_type： 杂志文章
doi：10.1111/j.1464-410X.2009.08845.x
更新日期：2010-06-01 00:00:00
abstract：OBJECTIVE:To determine the overall tolerability of urodynamic studies used in the assessment of men with lower urinary tract symptoms (LUTS), by assessing the objective and subjective morbidity experienced during and after urodynamic studies, and to assess the voiding complaints caused by the combination of urodynamic ...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.1999.00222.x
更新日期：1999-09-01 00:00:00
