Abstract:
OBJECTIVE:To present two patients with the tuberous sclerosis complex in whom giant angiomyolipomas (AMLs) were managed conservatively for >20 years, as large (>4 cm) symptomatic AMLs are generally treated with embolization or nephrectomy because of the risks of haemorrhage. PATIENTS AND METHODS:The first patient initially presented with bilateral renal AMLs replacing >70% of his parenchymal volume, and a large left renal cyst. Since presentation he was hospitalized three times, but has had no transfusions or procedures to treat his AMLs. His renal function has remained stable during this 21-year interval. The second patient initially presented with bilateral renal AMLs that were not amenable to nephron-sparing surgery. After removing her nonfunctioning left kidney, the 24-cm AML in her right kidney was managed conservatively for >20 years, during which she had 44 transfusions and 11 hospitalizations before uncomplicated right nephrectomy and subsequent need for haemodialysis. CONCLUSION:Conservative management of AMLs can preserve renal function for >20 years in patients with tuberous sclerosis at high risk of end-stage renal disease.
journal_name
BJU Intjournal_title
BJU internationalauthors
Danforth TL,Lane BR,Novick ACdoi
10.1111/j.1464-410X.2007.07059.xsubject
Has Abstractpub_date
2007-10-01 00:00:00pages
794-7issue
4eissn
1464-4096issn
1464-410Xpii
BJU7059journal_volume
100pub_type
杂志文章abstract:OBJECTIVE:To estimate the prevalence of nocturia in the Dutch adult population, its association with sociodemographic and health characteristics, and to assess problems experienced by persons with nocturia. SUBJECTS AND METHODS:In spring 2001 a telephone survey was conducted among a representative sample of 4721 Dutch...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2002.03011.x
更新日期:2002-11-01 00:00:00
abstract:UNLABELLED:What's known on the subject? and What does the study add? Renal forniceal rupture is a common finding in patients with ureteral obstruction. It is thought to be due to increased renal pelvis pressure from backup of urine, causing one or more renal fornices to leak urine. This phenomenon has not been systemat...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2011.10164.x
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the diffusion of nephron-sparing modalities (NSM) for the treatment of renal neoplasms in the USA over the last decade and to identify the factors associated with renal procedure selection. PATIENTS AND METHODS:The Nationwide Inpatient Sample was utlized to identify patients undergoing cryo/radio...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.11497.x
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVES:To retrospectively review hypogonadal men receiving testosterone replacement therapy (TRT), and evaluate the changes in prostate-specific antigen (PSA) levels over an extended period, and thus evaluate the occurrence of prostate cancer, as a primary concern in treating late-onset hypogonadism (LOH) is the po...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.08240.x
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:To investigate the clinical utility of frozen section (FS) analysis performed during partial nephrectomy (PN) and its influence on intra-operative management. PATIENTS AND METHODS:We performed a retrospective analysis of consecutive PN cases from 2010 to 2013. We evaluated the concordance between the intra-o...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13011
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:To investigate the incidence of bone fractures in patients receiving luteinizing hormone-releasing hormone agonists (LHRH-a) for prostate cancer (in whom a continued low testosterone level after the long-term administration of these drugs reduces bone mineral density), and thus determine the risk of secondary...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2000.00774.x
更新日期:2000-09-01 00:00:00
abstract::There is ample evidence from many epidemiological studies that lower urinary tract symptoms (LUTS) and sexual dysfunction are strongly linked, independently of age and comorbidities such as hypertension, diabetes, dyslipidaemia and coronary heart disease. However, a causal link between both conditions is not yet estab...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2006.06102.x
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVES:To investigate whether ureteroscopy (URS) before radical nephroureterectomy (RNU) for upper tract urothelial carcinomas (UTUCs) has an impact on oncological outcomes. PATIENTS AND METHODS:We performed a systematic literature search of PubMed, Web of Science, and EMBASE for citations published prior to Septe...
journal_title:BJU international
pub_type: 杂志文章,meta分析,评审
doi:10.1111/bju.14053
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:To determine the relationship of age to side-effects leading to discontinuation of treatment in patients with stage Ta-T1 non-muscle-invasive bladder cancer (NMIBC) treated with maintenance bacille Calmette-Guérin (BCG). PATIENTS AND METHODS:We evaluated toxicity for 487 eligible patients with intermediate- ...
journal_title:BJU international
pub_type: 杂志文章,随机对照试验
doi:10.1111/bju.13474
更新日期:2016-09-01 00:00:00
abstract::The introduction of prostate-specific antigen (PSA) has revolutionized the detection and management of patients with prostate cancer. Despite this there has always been a concern among clinicians about the usefulness of total PSA levels as a marker for prostate cancer. We discuss the use of calculated variables and mo...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2007.07283.x
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVE:To review a series of children with anterior urethral valves and diverticula, to elucidate the pathophysiology and optimal management of this entity. PATIENTS AND METHODS:Nine cases (all boys; 1963 to 2003) were reviewed retrospectively. RESULTS:Seven of nine boys had bulbar diverticula. Continuity between ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2004.04854.x
更新日期:2004-08-01 00:00:00
abstract:UNLABELLED:What's known on the subject? and What does the study add? Upper Urinary Tract (UUT) Transitional Cell Carcinoma (TCC) is an uncommon disease and represents approximately 5% of all urothelial carcinomas. We report our series on 73 patients treated with Kidney Sparing Surgery for UUT TCC. Good results have bee...
journal_title:BJU international
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/j.1464-410X.2012.11554.x
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:To assess the feasibility of a pure endoscopic closure method for vesical perforations using fully absorbable material. MATERIALS AND METHODS:A pilot experimental study was performed in eight anaesthetized female pigs. Four 10-mm and four 20-mm endoscopic full thickness cystotomies were created. An endoscopi...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12688
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:To review patients who had vesico-ureteric reflux corrected surgically by ureteric reimplantation during childhood, and thus assess their long-term outcome. PATIENTS AND METHODS:Between 1970 and 1979, 322 children underwent ureteric reimplantation; 100 (79 women and 21 men) were re-assessed and the long-term...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2003.04264.x
更新日期:2003-07-01 00:00:00
abstract:OBJECTIVE:To propose a standardisable composite method for reporting outcomes of radical cystectomy (RC) that incorporates both perioperative morbidity and oncological adequacy. PATIENTS AND METHODS:From July 2010 to December 2017, 277 consecutive patients who underwent robot-assisted RC with intracorporeal urinary di...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.14861
更新日期:2020-01-01 00:00:00
abstract::There has been a recent increase in mumps orchitis among pubertal and postpubertal males. These outbreaks can be attributed to a reduction in the uptake of measles-mumps-rubella (MMR) vaccine during the early to mid-1990 s in children who have now matured. The mumps virus is commonly associated with extra-salivary com...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2009.09148.x
更新日期:2010-04-01 00:00:00
abstract:STUDY TYPE:Therapy (case series) Level of Evidence 4. OBJECTIVE:To report our analysis of the oncological outcome, side-effects and complications after (125)I-brachytherapy, based on 10 years of experience, as low dose-rate (LDR) prostate brachytherapy is an accepted, effective and safe therapy for localized prostate ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2009.09096.x
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:To determine whether conformity to standard recommendations of retroperitoneal lymph node dissection (RPLND) after chemotherapy for testicular and primary retroperitoneal nonseminomatous germ cell tumours (NSGCT) and completeness of surgical excision have an effect on oncological outcome. PATIENTS AND METHOD...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2009.09175.x
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVE:To describe our experience of penile urethral repair and reconstruction, cataloguing the change in practice from one-stage flap to two-stage free graft procedures for anterior urethroplasty. PATIENTS AND METHODS:Between January 1992 and December 1996, 79 patients underwent anterior urethroplasty. Of the 45 o...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.1999.00010.x
更新日期:1999-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the comparative effectiveness of electromyographic (EMG) biofeedback with verbal instructions as learning tools of pelvic muscle exercises (PMEs) in the early management of urinary incontinence after radical prostatectomy. PATIENTS AND METHODS:Forty-two consecutive patients (mean age 64 years, sd...
journal_title:BJU international
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1046/j.1464-410x.2002.02721.x
更新日期:2002-05-01 00:00:00
abstract:UNLABELLED:Study Type - Therapy (RCT) Level of Evidence 1b What's known on the subject? and What does the study add? Men with prostate cancer have higher rates of non-cancer mortality and CV morbidity and some of that excess risk has been attributed to the treatment they receive. ADT is an established treatment option ...
journal_title:BJU international
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1464-410X.2011.10555.x
更新日期:2012-05-01 00:00:00
abstract:UNLABELLED:What's known on the subject? and What does the study add? Elderly patients have more years to compound comorbidities and it has previously been shown that comorbidity is an important predictor of overall survival in patients with bladder cancer, including those treated with radical cystectomy (RC). Other stu...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1464-410X.2012.11180.x
更新日期:2012-12-01 00:00:00
abstract::Since Huggins and Hodges demonstrated the responsiveness of prostate cancer to androgen deprivation therapy (ADT), androgen-suppressing strategies have formed the cornerstone of management of advanced prostate cancer. Approaches to ADT have included orchidectomy, oestrogens, luteinizing hormone-releasing hormone (LHRH...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2012.11215.x
更新日期:2012-06-01 00:00:00
abstract:UNLABELLED:WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: The EndoSew(®) prototype was first tested in a porcine model several years ago. The investigators found it both simple to master and reliable, its greatest advantage being a 2.4-fold time saving compared with straight laparoscopic suturing. In additi...
journal_title:BJU international
pub_type: 临床试验,杂志文章
doi:10.1111/j.1464-410X.2012.11599.x
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVES:To evaluate the safety and efficacy of stereotactic radiotherapy (SRT) in patients with metastatic renal cell carcinoma (mRCC) concurrently receiving targeted therapy (TT) or immunotherapy. PATIENTS AND METHODS:Data on patients with mRCC were extracted from a retrospective international multicentre register...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.15284
更新日期:2020-10-28 00:00:00
abstract::For the delivery of good-quality external beam radiotherapy (EBRT) in localized prostate cancer, under-dosage to the peripheral zone (tumour) is one likely cause of poor results. The quality is improved by daily verification of the position of the prostate, and the use of magnetic resonance imaging (MRI) in delineatio...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2007.07346.x
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the suitability of preoperative multiparametric magnetic resonance imaging (MRI) positivity as a predictor of biochemical recurrence after radical prostatectomy (RP). PATIENTS AND METHODS:We reviewed the clinical records of patients who underwent either standard RP or laparoscopic RP between Janu...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12329
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVE:To determine the 5-year oncological outcomes of endoscopic extraperitoneal radical prostatectomy (EERPE) from a medium-volume centre, thereby providing much needed data on outcomes from the UK. PATIENTS AND METHODS:From January 2006 to January 2012, 575 patients underwent EERPE for localized prostate cancer,...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12260
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVE:To evaluate two methods of reducing the urine output during treatment (the most easily manipulated variable) in patients undergoing intravesical instillation with mitomycin C, where the concentration-time curve also depends upon dose, diluent volume, residual urine volume, and drug absorption and degradation....
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2000.00869.x
更新日期:2000-10-01 00:00:00
abstract:OBJECTIVE:To quantify the incremental detection rate (DR) of a targeted biopsy in addition to a randomized 10-core biopsy. PATIENTS AND METHODS:This retrospective study analysed 1024 patients who consecutively underwent a four-core real-time elastography (RTE) targeted biopsies in addition to a randomized 10-core tran...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12517
更新日期:2014-04-01 00:00:00