Abstract:
OBJECTIVE:To assess psychometrically a new questionnaire for measuring the psychosocial morbidity in patients with prostate cancer and in their partners, and to compare the morbidity of patients and their partners. PATIENTS AND METHODS:A sequential sample of patients with any stage of prostate cancer and attending general urology outpatient clinics was identified. The questionnaire was administered to 135 patients and their partners in their homes. The Hospital Anxiety and Depression Scale (HADS) questionnaire was also administered to permit construct validation of the new measure. Test-retest reliability was calculated by re-administering the questionnaire to 60 individuals. The hypothetical general cancer distress and social subscales of the questionnaire were also tested for internal consistency. Psychosocial morbidity scores obtained by the patients and partners were compared. RESULTS:The questionnaire had good test-retest reliability and construct validity when tested against the HADS. The general cancer distress and social subscales were internally consistent. General cancer distress was highly prevalent and significantly more severe in partners than in patients. There was some degree of general cancer distress in 47% of patients and 76% of partners, whereas severe distress was detected in 11% and 30%, respectively. Social morbidity was limited and of equal severity between the groups. Treatment-related worries and concerns about pain and physical limitation were more common among partners than patients, whereas there was no difference for worries about urinary symptoms. Sexual concerns were the least prevalent and were more of a problem for patients than partners. CONCLUSION:Psychosocial morbidity in prostate cancer is highly prevalent, not only among patients but particularly among their partners. The new questionnaire showed adequate psychometric properties for use in identifying individuals with significant psychosocial morbidity. Applying the questionnaire should permit emotional and informational support to be targeted at the most vulnerable.
journal_name
BJU Intjournal_title
BJU internationalauthors
Cliff AM,MacDonagh RPdoi
10.1046/j.1464-410x.2000.00914.xkeywords:
subject
Has Abstractpub_date
2000-11-01 00:00:00pages
834-9issue
7eissn
1464-4096issn
1464-410Xpii
bju914journal_volume
86pub_type
杂志文章abstract:OBJECTIVE:To review long-term oncological and functional outcomes of testicular-sparing surgery (TSS) in men presenting with bilateral or monorchide testicular tumours at one of five reference centres for testicular neoplasm and infertility. PATIENTS AND METHODS:We review 25 cases of bilateral synchrone and metachrone...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/bju.12549
更新日期:2014-12-01 00:00:00
abstract::Metastases to regional lymph nodes are a common early event in many malignant diseases and have a poor prognosis, including in urological cancers. Molecular pathways contributing to lymphatic tumour dissemination and lymph node metastasis remain poorly understood. Besides the process of lymphovascular invasion (LVI), ...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2009.08704.x
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:To determine if patients who undergo tubularized incised-plate (TIP) urethroplasty need regular dilatation to prevent neourethral strictures or meatal stenosis. PATIENTS AND METHODS:The follow-up of two consecutive series of patients who underwent primary TIP hypospadias repair by one surgeon was reviewed. T...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-4096.2001.01901.x
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:To examine the effects of castration and continuous gonadotrophin releasing-hormone (GnRH) agonist and antagonist therapy on the expression of GnRH-receptors type I (GnRH-RI) in rat ventral prostate (VP) and pituitary tissue, and to compare the effects on prostate morphology. MATERIAL AND METHODS:Mature Spra...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2003.03054.x
更新日期:2003-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the insertion of a urethral sling at the time of radical prostatectomy (RP) in men at high risk of urinary incontinence after RP. PATIENTS AND METHODS:Between 1998 and 2000, 49 of 871 men undergoing RP at The University of Texas M.D. Anderson Cancer Center, were identified as at risk of urinary i...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2006.06220.x
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVE:To investigate the possibility of using urodynamic variables to predict upper urinary tract dilatation (UUTD) in children with neurogenic bladder-sphincter dysfunction (NBSD). PATIENTS AND METHODS:The study included 200 children with NBSD, of whom 103 had UUTD and 97 did not; they were examined using routine...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2006.06402.x
更新日期:2006-12-01 00:00:00
abstract:OBJECTIVE:To assess the prevalence of obstructive sleep apnoea (OSA) in men presenting with erectile dysfunction (ED) at a single centre. PATIENTS AND METHODS:All men attending a specialised andrology outpatient department with a new diagnosis of ED were included in this prospective study. All patients completed three...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13961
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:To determine the effect of various treatments for benign prostatic hyperplasia (BPH) on sexual function. PATIENTS AND METHODS:In a longitudinal multicentre study carried out in the Netherlands, 670 consecutive patients with BPH (aged > or = 50 years) were examined at baseline and 9 months after inclusion. Al...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1046/j.1464-4096.2001.01817.x
更新日期:2002-02-01 00:00:00
abstract:OBJECTIVES:To examine patterns of care among women with urogenital fistula treated in the English National Health Service (NHS) between 2000 and 2009. To assess whether failure of repair was associated with hospital or surgeon workload. PATIENTS AND METHODS:We conducted a retrospective cohort study using data from Hos...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1464-410X.2012.11483.x
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVE:To determine the outcome 10 years after an individual course of pelvic floor muscle (PFM) exercises for genuine stress incontinence. PATIENTS AND METHODS:Postal questionnaires were sent to 52 women who had undergone PFM training 10 years earlier, and their medical files were reviewed. The main outcome measur...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2000.00506.x
更新日期:2000-04-01 00:00:00
abstract:OBJECTIVES:To help clarify which small renal cortical neoplasms (RCNs) require surgery by using office-based, ultrasonography-guided percutaneous renal biopsy. PATIENTS AND METHODS:Biopsies were performed using facilitated ultrasound targeting (FUT) technology, which incorporates a needle guide and onscreen beam-steer...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12489
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVES:To evaluate the effects of 50 mg mirabegron once daily for ureteric stent-related discomfort after ureteroscopic procedures by conducting a multicentre randomized study. PATIENTS AND METHODS:A total of 100 patients with indwelling ureteric stents after ureteroscopic stone removal or retrograde intrarenal su...
journal_title:BJU international
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/bju.14416
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:To examine the chemopreventive effects of a selective cyclooxygenase (COX)-2 inhibitor, meloxicam, and a selective epidermal growth factor (EGF)-receptor tyrosine kinase inhibitor, gefitinib (as a single agent) on a carcinogen-induced rodent bladder carcinogenesis model. MATERIALS AND METHODS:The study compr...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2006.06053.x
更新日期:2006-03-01 00:00:00
abstract::OBJECTIVE To investigate the incidence of new-onset diabetes mellitus (NODM) and of worsening glycaemic control in established DM after starting androgen-deprivation therapy (ADT) for prostate cancer, as ADT is associated with altered body composition, potentially influencing insulin sensitivity. PATIENTS AND METHODS ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2007.07184.x
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVES:• To investigate a new method of vas deferens radiography for ejaculatory duct obstruction (EDO). • To evaluate the effect of a procedure involving dilation of the ejaculatory duct by F9 seminal vesicoscopy. PATIENTS AND METHODS:• Twenty-two patients with EDO were diagnosed using semen analysis, semen fruct...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09775.x
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVES:To determine the proportion of solitary rib lesions on pre-treatment 68 Gallium-labelled prostate-specific membrane antigen (PSMA)/computed tomography (CT) scans in men with prostate cancer that are malignant and examine any predictive factors. PATIENTS AND METHODS:This retrospective single tertiary referra...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.15152
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVES:To determine if baseline characteristics, treatment efficacy, psychosocial outcomes or tolerability were associated with patient preference for sildenafil citrate (sildenafil) or tadalafil for treating erectile dysfunction (ED) in men naive to phosphodiesterase 5 inhibitor therapy. PATIENTS AND METHODS:In a...
journal_title:BJU international
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1464-410X.2007.06916.x
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVE:To report a large multi-institutional series of laparoendoscopic single-site (LESS) nephroureterectomy (NU). MATERIALS AND METHODS:Data on all cases of LESS-NU performed between 2008 and 2012 at 15 institutions were retrospectively gathered. The main demographic data and perioperative outcomes were analysed....
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1464-410X.2012.11775.x
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the association between the International Prostate Symptom Score (IPSS) bother question (BQ) and a validated disease-specific quality-of-life questionnaire, the Benign Prostatic Hyperplasia (BPH) Impact Index (BPH-II), using the BPH Registry and Patient Survey database. PATIENTS AND METHODS:The B...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1464-410X.2008.07574.x
更新日期:2008-06-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2005.05741.x
更新日期:2005-11-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2004.04998.x
更新日期:2004-09-01 00:00:00
abstract::Data from the Japanese Urological Society showed that, in Japan, almost half of patients with localized prostate cancer are treated with hormone therapy (HT), regardless of disease stage, and that radiation therapy (RT) is also widely used to treat high-risk patients. A retrospective study was undertaken in Japan to e...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2007.06592.x
更新日期:2007-01-01 00:00:00
abstract:UNLABELLED:What's known on the subject? and What does the study add? The common clinical practice for advanced prostatic adenocarcinoma is combination therapy of zoledronic acid (ZA) and docetaxel (TAX). Little is known about the consequences of this combination therapy with regard to osteonecrosis of the jaw (ONJ). Th...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1464-410X.2012.11205.x
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:• To systematically review the literature on gemcitabine chemotherapy for advanced or metastatic bladder cancer. MATERIALS AND METHODS:• The Medical Literature Analysis and Retrieval System Onlinedatabase (MEDLINE), the Excerpta Medicadatabase (EMBASE), the Cumulative Index to Nursing and Allied Health Liter...
journal_title:BJU international
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1464-410X.2011.10341.x
更新日期:2011-07-01 00:00:00
abstract:UNLABELLED:Study Type--Therapy (outcomes) Level of Evidence 2a. What's known on the subject? and What does the study add? Erectile dysfunction (ED) is a well known implication of radical prostatectomy (RP). Despite the search for technical improvement in the surgical procedure (e.g. nerve-sparing surgery, robot-assiste...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.11484.x
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:To compare the outcome of a modified one-layer and two-layer vasovasotomy (VV) in two groups of similar men undergoing vasectomy reversal. PATIENTS AND METHODS:The charts and surgical records of all surgical procedures performed on men undergoing a modified one- or two-layer VV between June 1992 and July 199...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2000.00668.x
更新日期:2000-06-01 00:00:00
abstract:OBJECTIVE:To investigate possible differences between Italian and Swedish men in health-related quality of life (HRQL) after cystectomy and orthotopic bladder substitution for bladder cancer. PATIENTS AND METHODS:Thirty-three men in Padua, Italy and 33 in Lund, Sweden were assessed after respective mean postoperative ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2000.00416.x
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:To systematically review and create nomograms of flaccid and erect penile size measurements. METHODS:Study key eligibility criteria: measurement of penis size by a health professional using a standard procedure; a minimum of 50 participants per sample. EXCLUSION CRITERIA:samples with a congenital or acquire...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/bju.13010
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVE:To examine the utility of cyanoacrylate tissue adhesive (Dermabond, Ethicon, Somerville, NJ, USA; an effective means of epithelial skin closure) under a diaper (i.e. constantly exposed to bodily fluids) in 25 children (not toilet-trained) undergoing inguinal surgery. PATIENTS AND METHODS:A retrospective revi...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2001.02142.x
更新日期:2001-05-01 00:00:00
abstract:UNLABELLED:WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: Erectile dysfunction after nerve-sparing radical retropubic prostatectomy constitutes a challenge to the urologist. The mainstay of medical treatment after radical prostatectomy to restore spontaneous erectile function remains phosphodiesterase (PDE5...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.11561.x
更新日期:2013-07-01 00:00:00