Abstract:
OBJECTIVES:To examine patterns of care among women with urogenital fistula treated in the English National Health Service (NHS) between 2000 and 2009. To assess whether failure of repair was associated with hospital or surgeon workload. PATIENTS AND METHODS:We conducted a retrospective cohort study using data from Hospital Episode Statistics on women undergoing vesicovaginal or urethrovaginal fistula repair between January 2000 and December 2009 in English NHS hospitals. The main outcome measure was the number of fistula repairs and the incidence of re-repair; re-repair rates were stratified by age, NHS trust and consultant team volume. RESULTS:Between 2000 and 2009, 1194 women underwent surgical repair (n = 905) or ileal conduit (n = 289) for urogenital fistula under the care of 490 consultant teams. A total of 281 teams performed only a single index procedure, and only three consultant teams performed a mean of >3 per year. The rate of unsuccessful repair was 11.9% (108/905). The rate of re-operation at NHS trusts who performed over 30 procedures over the 10-year study period was 7.4% compared with 13.2% at those undertaking fewer (P = 0.02). A similar difference in re-operations between consultant teams performing > or <30 procedures did not reach significance (8.4% v 12.7%, P = 0.13). CONCLUSIONS:One in nine women required re-operation after surgical repair of a urogenital fistula. Our results lend weight to the argument for a 'minimum workload' for fistula management; given the number of fistulae occurring in England currently, this would best be provided by a network of supra-regional centres.
journal_name
BJU Intjournal_title
BJU internationalauthors
Cromwell D,Hilton Pdoi
10.1111/j.1464-410X.2012.11483.xsubject
Has Abstractpub_date
2013-04-01 00:00:00pages
E257-62issue
4 Pt Beissn
1464-4096issn
1464-410Xjournal_volume
111pub_type
杂志文章,多中心研究abstract::Study Type - Therapy (case series) Level of Evidence 4 What's known on the subject? and What does the study add? The resection of the distal ureter and its orifice is an oncological principle during radical nephroureterectomy which is based on the fact that it represents a part of the urinary tract exposed to a consid...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2010.09835.x
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:To analyse the performance of the Prostate Cancer Prevention Trial Risk Calculator (PCPT-RC) and two iterations of the European Randomised Study of Screening for Prostate Cancer (ERSPC) Risk Calculator, one of which incorporates prostate volume (ERSPC-RC) and the other of which incorporates prostate volume an...
journal_title:BJU international
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/bju.13437
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:To determine the incidence of detrusor instability (DI) detected by conventional and ambulatory bladder pressure monitoring, any link between urodynamic findings before and after colposuspension, and between patients' symptoms and the urodynamic findings. PATIENTS AND METHODS:Sixty-five patients, scheduled t...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.1999.00390.x
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVE:To study a novel penile reinnervation technique using four sural nerve grafts and end-to-side neurorraphies connecting bilaterally the femoral nerve and the cavernous corpus and the femoral nerve and the dorsal penile nerves. PATIENTS AND METHODS:Ten patients (mean [± sd; range] age 60.3 [± 4.8; 54-68] years...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13772
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVES:To assess atypical cytology as a positive bladder tumour marker and to determine if indexing atypical cytology to nuclear matrix protein-22 (NMP22) can decrease the false-positive results or increase the positive predictive value (PPV). PATIENTS AND METHODS:In all, 197 patients at risk of bladder cancer wer...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.07789.x
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVE:To evaluate changes in protein leakage in the glomerular filtration barrier, and in the ability of the tubule to reabsorb proteins during and after acute urinary retention (AUR). PATIENTS AND METHODS:Glomerular and tubular function was investigated in 24 men during AUR (mean age 68 years, mean retention time...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2001.02047.x
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVE:To create an experimental animal model to examine changes in bladder volume and histology after bladder augmentation in growing individuals and from the model, evaluate a method using demucosalized intestinal grafts and short-term bladder drainage. MATERIALS AND METHODS:The study comprised 21 piglets: in gro...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.1999.00895.x
更新日期:1999-02-01 00:00:00
abstract:OBJECTIVE:To investigate the incidence of bone fractures in patients receiving luteinizing hormone-releasing hormone agonists (LHRH-a) for prostate cancer (in whom a continued low testosterone level after the long-term administration of these drugs reduces bone mineral density), and thus determine the risk of secondary...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2000.00774.x
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVE:To highlight the existence of Schistosoma haematobium in certain ethnic minority groups in Britain and in English citizens who have recently visited Africa and the Middle East, so that general practitioners and paediatric nephrologists/urologists are aware of its occurrence and consider it among the different...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2000.00477.x
更新日期:2000-02-01 00:00:00
abstract:UNLABELLED:What's known on the subject? and What does the study add? In the 1980s and 1990s, a method for direct measurement of pressure and cross-sectional area in women and men was developed. It was successful in terms of obtaining meaningful results in several studies. But the technique, which was based on the field...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.10997.x
更新日期:2012-10-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09185.x
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the perioperative and pathological outcomes associated with robot-assisted radical prostatectomy (RARP) in morbidly obese men. PATIENTS AND METHODS:Between January 2008 and March 2012, 3041 patients underwent RARP at our institution by a single surgeon (V.P.). In all, 44 patients were considered ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2013.11798.x
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To measure the prevalence of nocturia in general practice and to determine which factors are associated with nocturia. SUBJECTS AND METHODS:Data were collected from 3048 elderly men, who completed a questionnaire that was sent to every man aged 55-75 years in 21 general practices in Maastricht (the Netherlan...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1464-410X.2006.06029.x
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVE:To validate a hypothesis that prostate cancer can be detected non-invasively by a simple and reliable assay by targeting genomic VPAC receptors expressed on malignant prostate cancer cells shed in voided urine. PATIENTS/SUBJECTS AND METHODS:VPAC receptors were targeted with a specific biomolecule, TP4303, de...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13775
更新日期:2017-06-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13023
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:To report the outcomes of >1000 men with low-risk prostate cancer treated with low-dose-rate (LDR) brachytherapy at three large UK cancer centres. PATIENTS AND METHODS:A total of 1038 patients with low-risk prostate cancer (prostate-specific antigen [PSA] ≤10 ng/mL, Gleason score 6, ≤T2b disease) were treate...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/bju.12358
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVE:To detect occult regional lymph node metastases in patients with T3pN0M0 prostate cancer not recognized by routine haematoxylin and eosin staining, and to evaluate the clinical relevance of this finding. PATIENTS AND METHODS:Formalin-fixed and paraffin-embedded pelvic lymph nodes (1118) from 92 patients were...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2000.00406.x
更新日期:2000-02-01 00:00:00
abstract:UNLABELLED:What's known on the subject? and What does the study add? Percutaneous renal cryoablation is a safe and effective treatment for patients with small renal masses, who are poor surgical candidates. Oncological outcomes from previous percutaneous ablation studies are difficult to interpret because of the large ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.11230.x
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the activity of nilutamide as secondary hormonal therapy in patients with androgen-independent prostate cancer (AIPC), as treatment options are limited for these patients and secondary hormonal therapy with antiandrogens has advantages, including low toxicity, oral administration and high patient ...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1464-410X.2005.05714.x
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:To accurately define the anatomy of the neurovascular bundle (NVB) in men. MATERIALS AND METHODS:The NVB was microdissected in detail bilaterally in 12 fixed human male adult cadavers. The anatomy of the NVB and its relationship to surrounding pelvic structures was ascertained in each specimen. RESULTS:Prev...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2004.05106.x
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVE:To retrospectively review the long-term activity, efficacy and toxicity of the combination of paclitaxel, cisplatin and gemcitabine (TPG) as third- or further-line chemotherapy in patients with germ-cell tumours (GCTs) who are not cured after at least two courses of standard-dose chemotherapy, high-dose chemo...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2009.08453.x
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVES:To compare the prevalence of metabolic syndrome and the components of metabolic syndrome in men aged ≥50 years with and without clinical benign prostatic hyperplasia (BPH). SUBJECTS AND METHODS:This was a cross-sectional study using the UK Clinical Practice Research Datalink (CPRD). Men were selected from t...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13334
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:To study the incidence of postoperative systemic inflammatory response syndrome (SIRS) following different antibiotic prophylaxis (ABP) regimens in retrograde intrarenal surgery (RIRS). PATIENTS AND METHODS:Single-centre, randomised, controlled trial (August 2014-September 2017) including 426 patients with r...
journal_title:BJU international
pub_type: 杂志文章,随机对照试验
doi:10.1111/bju.14832
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:To evaluate how many patients could have undergone partial nephrectomy (PN) rather than radical nephrectomy (RN) before and after neoadjuvant axitinib therapy, as assessed by five independent urological oncologists, and to study the variability of inter-observer agreement. PATIENTS AND METHODS:Pre- and post-...
journal_title:BJU international
pub_type: 杂志文章,随机对照试验
doi:10.1111/bju.13188
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:To assess the safety and efficacy of the tension-free vaginal tape procedure in the treatment of primary genuine stress incontinence. PATIENTS AND METHODS:A two-centre follow-up study was conducted on 40 women with urodynamically confirmed primary genuine stress incontinence who had a tension-free vaginal ta...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1046/j.1464-410x.2000.00731.x
更新日期:2000-07-01 00:00:00
abstract:OBJECTIVES:To compare the serum levels of insulin-like growth factor-1 (IGF-1) in patients with prostate cancer and in control patients with no malignancy, and to evaluate any possible influence of testicular androgen withdrawal on the level of IGF-1 in patients with prostate cancer. PATIENTS AND METHODS:IGF-1 was mea...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2000.00350.x
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:To report the events during and after radical cystectomy and urinary diversion for bladder cancer, in terms of major and minor complications, comparing a minimal with an extended lymphadenectomy, as more lymph nodes obtained during radical cystectomy may improve staging and thus the outcome. PATIENTS AND MET...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1464-410x.2004.04557.x
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVES:To present the oncological and functional outcomes of salvage focal (SFC) and salvage total (STC) cryoablation for recurrent prostate cancer (PCa) after failed primary radiotherapy. PATIENTS AND METHODS:From March 2003 to August 2010, 50 men with biopsy-proven unilateral (n = 25) or bilateral (n = 25) radio...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12151
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVES:To examine the results of open partial nephrectomy (OPN) over a 15-year period in a large UK teaching hospital and to compare results with other series including minimally invasive techniques, as nephron-sparing techniques are still under-utilized in the surgical treatment of renal carcinoma. A standardized ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.07829.x
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVE:To provide comparative data on quality of life (QoL) after prostate cancer treatment to help patients make an informed decision regarding their choice of treatment. METHODS:Patients with pathologically proven, non-metastatic, T1-T3bN0 prostate cancer were included in this prospective non-randomized study if ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.14021
更新日期:2018-04-01 00:00:00