Nephron-sparing surgery: a call for greater application of established techniques.

abstract：OBJECTIVE:To identify predictors of delayed therapy with curative intent, an increasingly common option in contemporary patients with prostate cancer who initially choose watchful waiting. PATIENTS AND METHODS:The characteristics of all patients at one institution and diagnosed with T1-4NXM0 prostate cancer between 19...

journal_title：BJU international

authors： el-Geneidy M,Garzotto M,Panagiotou I,Hsieh YC,Mori M,Peters L,Klein T,Beer TM

更新日期：2004-03-01 00:00:00

abstract：UNLABELLED:What's known on the subject? and What does the study add? L-dopa decarboxylase (DDC) has been documented as a novel co-activator of androgen receptor transcriptional activity. Recently, it was shown that DDC gene expression is significantly higher in patients with PCa than in those with BPH. In the present s...

journal_title：BJU international

authors： Koutalellis G,Stravodimos K,Avgeris M,Mavridis K,Scorilas A,Lazaris A,Constantinides C

更新日期：2012-09-01 00:00:00

abstract：:We performed a systematic literature review to assess the current status of a totally intracorporeal robot-assisted radical cystectomy (RARC) approach. The current 'gold standard' for radical cystectomy remains open radical cystectomy. RARC has lagged behind robot-assisted prostatectomy in terms of adoption and percei...

journal_title：BJU international

authors： Collins JW,Wiklund NP

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:To determine whether the temperature of 2% lignocaine hydrochloride gel affects the initial discomfort during instillation into the male urethra. PATIENTS AND METHODS:Sixty consenting men were randomized to receive 11 mL of 2% lignocaine hydrochloride gel (Instillagel, Farco-Pharma GmbH, Cologne, Germany) at...

journal_title：BJU international

authors： Thompson TJ,Thompson N,O'Brien A,Young MR,McCleane G

更新日期：1999-12-01 00:00:00

abstract：:Advanced adrenal carcinoma remains a significant therapeutic challenge, with conventional approaches to systemic therapy having failed to achieve sustained objective remissions or major survival benefit in most instances. Several systemic therapies, including mitotane, suramin and gossypol, as well as cytotoxic agents...

journal_title：BJU international

authors： Costa R,Wesolowski R,Raghavan D

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:To investigate the clinical utility of frozen section (FS) analysis performed during partial nephrectomy (PN) and its influence on intra-operative management. PATIENTS AND METHODS:We performed a retrospective analysis of consecutive PN cases from 2010 to 2013. We evaluated the concordance between the intra-o...

journal_title：BJU international

authors： Gordetsky J,Gorin MA,Canner J,Ball MW,Pierorazio PM,Allaf ME,Epstein JI

更新日期：2015-12-01 00:00:00

abstract：UNLABELLED:Study Type--Therapy (outcomes) Level of Evidence 2a. What's known on the subject? and What does the study add? Erectile dysfunction (ED) is a well known implication of radical prostatectomy (RP). Despite the search for technical improvement in the surgical procedure (e.g. nerve-sparing surgery, robot-assiste...

journal_title：BJU international

authors： Polito M,d'Anzeo G,Conti A,Muzzonigro G

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To assess the prevalence of obstructive sleep apnoea (OSA) in men presenting with erectile dysfunction (ED) at a single centre. PATIENTS AND METHODS:All men attending a specialised andrology outpatient department with a new diagnosis of ED were included in this prospective study. All patients completed three...

journal_title：BJU international

authors： Kalejaiye O,Raheem AA,Moubasher A,Capece M,McNeillis S,Muneer A,Christopher AN,Garaffa G,Ralph DJ

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:• To evaluate the efficacy and safety of single-agent AMG 102, an investigational, fully human monoclonal antibody to hepatocyte growth factor/scatter factor (HGF/SF), in renal cell carcinoma (RCC). PATIENTS AND METHODS:• This open-label phase II study included patients ≥ 18 years old with histologically con...

journal_title：BJU international

authors： Schöffski P,Garcia JA,Stadler WM,Gil T,Jonasch E,Tagawa ST,Smitt M,Yang X,Oliner KS,Anderson A,Zhu M,Kabbinavar F

更新日期：2011-09-01 00:00:00

abstract：UNLABELLED:WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: It has been suggested that a very short positive margin does not confer additional risk of BCR after radical prostatectomy. This study shows that even very short PSM is associated with increased risk of BCR. OBJECTIVE:To re-evaluate, in a larger coh...

journal_title：BJU international

authors： Shikanov S,Marchetti P,Desai V,Razmaria A,Antic T,Al-Ahmadie H,Zagaja G,Eggener S,Brendler C,Shalhav A

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To determine the effect of a deep and narrow pelvis on apical positive surgical margins (PSM) at radical prostatectomy (RP), controlling for other clinical and pathological variables and surgical approach, i.e. open retropubic (RRP) vs laparoscopic (LRP), as apical dissection is expected to be more challengin...

journal_title：BJU international

authors： Matikainen MP,von Bodman CJ,Secin FP,Yunis LH,Vora K,Guillonneau B,Laudone V,Eastham JA,Scardino PT,Akin O,Rabbani F

更新日期：2010-09-01 00:00:00

abstract：UNLABELLED:What's known on the subject? and What does the study add? Positive surgical margins (PSMs) after radical prostatectomy are common, although their impact on the risk of disease recurrence is unknown. We examined the impact of PSMs on the risk of 'significant' biochemical recurrence stratified by their risk of...

journal_title：BJU international

authors： Corcoran NM,Hovens CM,Metcalfe C,Hong MK,Pedersen J,Casey RG,Peters J,Harewood L,Goldenberg SL,Costello AJ,Gleave ME

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVES:To re-evaluate the role of diabetes mellitus (DM) as a risk factor for penile implant infection by exploring the association between glycated haemoglobin (HbA1c) levels and penile implant infection rates and to define a threshold value that predicts implant infection. PATIENTS AND METHODS:We conducted a mul...

journal_title：BJU international

authors： Habous M,Tal R,Tealab A,Soliman T,Nassar M,Mekawi Z,Mahmoud S,Abdelwahab O,Elkhouly M,Kamr H,Remeah A,Binsaleh S,Ralph D,Mulhall J

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To measure dihydropyrimidine dehydrogenase (DPD), an enzyme involved in the metabolism of 5-fluorouracil (5-FU), expression in prostate cancer and determine whether 5-chloro-2,4-dihydroxypyridine (CDHP), a potent inhibitor of DPD, enhances the antitumoral activity of 5-FU against prostate cancer. PATIENTS, M...

journal_title：BJU international

authors： Li Y,Mizutani Y,Shiraishi T,Nakamura T,Mikami K,Takaha N,Okihara K,Kawauchi A,Sakai T,Miki T

更新日期：2007-03-01 00:00:00

abstract：UNLABELLED:What's known on the subject? and What does the study add? There have been few studies evaluating the prognostic value of epithelial-mesenchymal transition markers in renal cell carcinoma (RCC); therefore, the significance of these markers in the prognosis of patients with RCC, particularly that in those with...

journal_title：BJU international

authors： Harada K,Miyake H,Kusuda Y,Fujisawa M

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the epidemiology of lower urinary tract symptoms (LUTS) among men and women, as there are significant unanswered questions about the prevalence and impact of LUTS in different populations. SUBJECTS AND METHODS:A population-based, cross-sectional survey was completed in Boxmeer (the Netherlands), ...

journal_title：BJU international

authors： Boyle P,Robertson C,Mazzetta C,Keech M,Hobbs FD,Fourcade R,Kiemeney L,Lee C,UrEpik Study Group.

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVES:To describe the step-by-step learning curve of the holmium laser enucleation of the prostate (HoLEP) surgical technique. SUBJECTS/PATIENTS AND METHODS:A prospective, multicentre observational study was conducted, involving surgeons experienced in transurethral resection of the prostate and open prostatectom...

journal_title：BJU international

authors： Robert G,Cornu JN,Fourmarier M,Saussine C,Descazeaud A,Azzouzi AR,Vicaut E,Lukacs B

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:To demonstrate an ergonomic fourth arm technique to oversew the dorsal vascular complex (DVC) during robot-assisted laparoscopic prostatectomy (RALP). PATIENTS AND METHODS:Balloon of a Foley catheter inflated in the bulbar urethra. Fourth arm cranial traction via suture in the tip of the catheter. DVC overse...

journal_title：BJU international

authors： Karim O,Rao A,Marsdin E,Kavia R,Parnham A,Motiwala H,Laniado M

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To determine if the adjunctive use of power Doppler imaging (PDI) could provide prognostic utility in the treatment of prostate cancer, as an accurate prediction of the clinical behaviour of prostate cancer is important to determine appropriate treatment. PATIENTS AND METHODS:Most centres rely on a digital r...

journal_title：BJU international

authors： Eisenberg ML,Cowan JE,Carroll PR,Shinohara K

更新日期：2010-05-01 00:00:00

abstract：:Detailed molecular insights into bladder cancer biology might allow more detailed prognostication and optimization of treatment with the objective of improving patient outcome and quality of life. However, in bladder cancer research the search for biomarkers has been called into question and has even obtained notoriet...

journal_title：BJU international

authors： Bryan RT,Zeegers MP,James ND,Wallace DM,Cheng KK

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To develop a rat model of erectile dysfunction (ED) after cavernous nerve injury. MATERIALS AND METHODS:Given the great similarity between the anatomical structure of the cavernous nerve in rats and humans, 24 rats underwent dissections and the cavernous nerves were identified with the aid of an operating mi...

journal_title：BJU international

authors： Kaufmann O,Claro J,Cury J,Andrade E,Longo B,Aguiar W,Mello L,Srougi M

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:• To analyse the overall and type-specific human papillomavirus (HPV) prevalence and distribution in penile carcinoma and determine the correlation to histopathological parameters. PATIENTS AND METHODS:• In this retrospective study, we analysed HPV status in 241 patients with penile carcinoma, treated at Öre...

journal_title：BJU international

authors： Kirrander P,Kolaric A,Helenius G,Windahl T,Andrén O,Stark JR,Lillsunde-Larsson G,Elgh F,Karlsson M

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:• Obesity induced by high-fat diet (HFD) is one of the most important risk factor for the development of erectile dysfunction (ED) in man. This study aimed to characterize the ED resulting from obesity associated with HFD in mice. MATERIALS AND METHODS:• C57BL/6 mice fed for 10 weeks with either HFD to induc...

journal_title：BJU international

authors： Toque HA,da Silva FH,Calixto MC,Lintomen L,Schenka AA,Saad MJ,Zanesco A,Antunes E

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:To collect data on voiding patterns at baseline (no treatment) and during short-term desmopressin treatment, with special reference to the functional and the mean bladder capacity. PATIENTS AND METHODS:The study included 120 children (aged 6-16 years) with monosymptomatic nocturnal enuresis. While at home th...

journal_title：BJU international

authors： Hvistendahl GM,Rawashdeh YF,Kamperis K,Hansen MN,Rittig S,Djurhuus JC

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the activity of nilutamide as secondary hormonal therapy in patients with androgen-independent prostate cancer (AIPC), as treatment options are limited for these patients and secondary hormonal therapy with antiandrogens has advantages, including low toxicity, oral administration and high patient ...

journal_title：BJU international

authors： Nakabayashi M,Regan MM,Lifsey D,Kantoff PW,Taplin ME,Sartor O,Oh WK

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVES:To assess the utility of perceived control over ejaculation ('control') in the evaluation of treatment benefit in men with premature ejaculation (PE), and to compare effects associated with a two-category or greater increase in this variable between men receiving dapoxetine and placebo. PATIENTS AND METHODS...

journal_title：BJU international

authors： Shabsigh R,Patrick DL,Rowland DL,Bull SA,Tesfaye F,Rothman M

更新日期：2008-09-01 00:00:00

abstract：UNLABELLED:What's known on the subject? and What does the study add? The clinical presentation and complications of lichen sclerosus are well known. What is less well known is the true incidence of the condition. The published figures are all based on attendance at general medical clinics or specialist clinics, but it ...

journal_title：BJU international

authors： Clouston D,Hall A,Lawrentschuk N

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVES:To compare the prevalence of metabolic syndrome and the components of metabolic syndrome in men aged ≥50 years with and without clinical benign prostatic hyperplasia (BPH). SUBJECTS AND METHODS:This was a cross-sectional study using the UK Clinical Practice Research Datalink (CPRD). Men were selected from t...

journal_title：BJU international

authors： DiBello JR,Ioannou C,Rees J,Challacombe B,Maskell J,Choudhury N,Kastner C,Kirby M

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:To evaluate the possible influence of non-pharmacological interventions, such as compressive bandages and intermittent pneumatic compression (IPC), on leg oedema and nocturnal polyuria (NP), and the possible interrelation between both pathologies in patients with spinal cord injury (SCI), as patients with SC...

journal_title：BJU international

authors： Viaene A,Roggeman S,Goessaert AS,Kessler TM,Mehnert U,Besien VV,De Muynck M,Everaert K

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVES:To report the clinical experience with a second-generation of temporary implantable nitinol device (iTIND; Medi-Tate Ltd, Or-Akiva, Israel) for the treatment of lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) after 1 year of follow-up. PATIENTS AND METHODS:In all, 81 patients w...

journal_title：BJU international

authors： Porpiglia F,Fiori C,Amparore D,Kadner G,Manit A,Valerio M,Nicolaas L,Ho BSH,Alonso S,Schulman C,Barber N

更新日期：2019-06-01 00:00:00