To determine whether the temperature of 2% lignocaine gel affects the initial discomfort which may be associated with its instillation into the male urethra.

Abstract:

OBJECTIVE:To determine whether the temperature of 2% lignocaine hydrochloride gel affects the initial discomfort during instillation into the male urethra. PATIENTS AND METHODS:Sixty consenting men were randomized to receive 11 mL of 2% lignocaine hydrochloride gel (Instillagel, Farco-Pharma GmbH, Cologne, Germany) at 4 degrees C, 22 degrees C or 40 degrees C. The three groups were well matched for age and numbers of previous flexible cystoscopies. The gel was instilled by one operator and the patients were then immediately asked to score the pain on instillation using a 100-mm nongraphical visual analogue scale. RESULTS:Compared with the control group (at 22 degrees C), there was a statistically significant reduction in pain score in the group receiving cold gel (Student's t-test, P<0.05). CONCLUSION:The cooling of 2% lignocaine gel significantly reduced the initial discomfort associated with its delivery into the male urethra before any form of urethral instrumentation.

journal_name

BJU Int

journal_title

BJU international

authors

Thompson TJ,Thompson N,O'Brien A,Young MR,McCleane G

doi

10.1046/j.1464-410x.1999.00346.x

keywords:

subject

Has Abstract

pub_date

1999-12-01 00:00:00

pages

1035-7

issue

9

eissn

1464-4096

issn

1464-410X

pii

bju346

journal_volume

84

pub_type

临床试验,杂志文章,随机对照试验
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