Glycosylated haemoglobin levels and the severity of erectile function in diabetic men.

Abstract:

OBJECTIVE:To evaluate the association between the levels of glycosylated haemoglobin (HbA1c) and the severity of erectile dysfunction (ED) in men with diabetes mellitus (DM). PATIENTS AND METHODS:This cross-sectional study included sexually active men with a diagnosis of DM attending a urological medical centre from January 2000 to December 2001. The 115 men with ED (95%) completed the International Index of Erectile Function questionnaire, and fasting serum glucose and HbA1c serum levels were measured. The relationship between the severity of ED and serum HbA1c levels was assessed. RESULTS:Of men with HbA1c levels of < 8%, half had mild, and 18% and 32% had moderate and severe ED, respectively (P = 0.038); of men with HbA1c levels of > or = 8%, 25%, 29%, and 46% had mild, moderate and severe ED, respectively (P = 0.008). In addition, men with HbA1c levels of > or = 11% had a statistically higher prevalence of severe ED (P = 0.002). There was no difference in severity of ED in the HbA1c subgroups when the duration of DM was < or = 5 years (P = 0.87), but most men with HbA1c levels of > or = 8% and a history of DM of 6-10 or > 10 years had severe ED (P < 0.03). CONCLUSION:This study suggests that the severity of ED is associated with increasing HbA1c levels in diabetic men.

journal_name

BJU Int

journal_title

BJU international

authors

Rhoden EL,Ribeiro EP,Riedner CE,Teloken C,Souto CA

doi

10.1111/j.1464-410X.2005.05349.x

keywords:

subject

Has Abstract

pub_date

2005-03-01 00:00:00

pages

615-7

issue

4

eissn

1464-4096

issn

1464-410X

pii

BJU5349

journal_volume

95

pub_type

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