Prostate cancer diagnosis in the new millennium: strengths and weaknesses of prostate-specific antigen and the discovery and clinical evaluation of prostate cancer gene 3 (PCA3).

abstract：OBJECTIVES:To identify differentially expressed genes between relapsed and non-relapsed clinical stage I testicular germ cell tumours (TGCTs). MATERIALS AND METHODS:We reviewed patients with clinical stage I non-seminoma and seminoma from an institutional database (2000-2012) who were managed by active surveillance. P...

journal_title：BJU international

authors： Lewin J,Soltan Ghoraie L,Bedard PL,Hamilton RJ,Chung P,Moore M,Jewett MAS,Anson-Cartwright L,Virtanen C,Winegarden N,Tsao J,Warde P,Sweet J,Haibe-Kains B,Hansen AR

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVES:To describe the step-by-step learning curve of the holmium laser enucleation of the prostate (HoLEP) surgical technique. SUBJECTS/PATIENTS AND METHODS:A prospective, multicentre observational study was conducted, involving surgeons experienced in transurethral resection of the prostate and open prostatectom...

journal_title：BJU international

authors： Robert G,Cornu JN,Fourmarier M,Saussine C,Descazeaud A,Azzouzi AR,Vicaut E,Lukacs B

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:To report our experience with the use of 95% ethanol as sclerotherapy for symptomatic simple renal cysts. PATIENTS AND METHODS:Sixty patients with 64 symptomatic simple renal cysts were treated by ultrasonography (US)-guided percutaneous aspiration and injection of 95% ethanol (31 men and 29 women, mean age ...

journal_title：BJU international

authors： Mohsen T,Gomha MA

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the justification for operative intervention in patients undergoing surgery for benign scrotal pathology, and to assess the associated morbidity. PATIENTS AND METHODS:Consecutive patients in two surgical firms who underwent surgery for benign intrascrotal pathology over a 5-year period were studi...

journal_title：BJU international

authors： Menon VS,Sheridan WG

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:• To evaluate the effect of transurethral resection of the prostate (TURP) on sexual function in the short (6 months), medium (6 years) and long (12 years) term and assess the conformity between patient and partner regarding sexual function. PATIENTS AND METHODS:• A prospective cohort study set at the Aberde...

journal_title：BJU international

authors： Mishriki SF,Grimsley SJ,Lam T,Nabi G,Cohen NP

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:To explore whether the number of unfavourable pretreatment risk factors predicts cause-specific mortality in men treated with prostate brachytherapy. PATIENTS AND METHODS:Between April 1995 and March 2006, 739 patients were treated who had at least one of the following adverse risk factors: pretreatment pros...

journal_title：BJU international

authors： Taira AV,Merrick GS,Galbreath RW,Butler WM,Lief JH,Wallner KE

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To investigate the validity of prostate-specific antigen (PSA) as a tumour marker in men with clinically localized prostate cancer who have selected watchful waiting, by determining if serial PSA level measurements are correlated with findings of malignancy or benign prostatic hyperplasia (BPH) at serial endo...

journal_title：BJU international

authors： Coakley FV,Chen I,Qayyum A,Westphalen AC,Carroll PR,Hricak H,Chen MH,Kurhanewicz J

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:To investigate the correlation of transient receptor potential vanilloid subfamily 1 (TRPV1) mRNA expression levels and the clinical outcome of intravesical resiniferatoxin treatment in patients with idiopathic detrusor overactivity (IDO), as such treatment with vanilloids can be effective for DO. PATIENTS ...

journal_title：BJU international

authors： Liu HT,Kuo HC

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To ascertain the potential thrombotic risk associated with transurethral prostatectomy (TURP). PATIENTS AND METHODS:The changes in coagulation variables were assessed in a prospective study of 40 patients undergoing TURP. RESULTS:There was a significant increase in thrombin-antithrombin complexes 6 h after ...

journal_title：BJU international

authors： Bell CR,Murdock PJ,Pasi KJ,Morgan RJ

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVE:To examine the feasibility and reproducibility of laser interstitial thermotherapy (LITT) as a minimally invasive method for the treatment of prostate cancer. MATERIALS AND METHODS:Heterotopic tumours of prostatic adenocarcinoma (Dunning R3327-AT2) were induced in 10 male Copenhagen rats. After preoperative ...

journal_title：BJU international

authors： Colin P,Nevoux P,Marqa M,Auger F,Leroy X,Villers A,Puech P,Mordon S,Betrouni N

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:To assess the potential use of bone marrow stromal cell (BMSC)-seeded biodegradable scaffold for bladder regeneration in a canine model, by characterizing BMSCs and comparing them to bladder smooth muscle cells (SMCs) by immunohistochemistry, growth capability, and contractility. MATERIALS AND METHODS:Bone m...

journal_title：BJU international

authors： Zhang Y,Lin HK,Frimberger D,Epstein RB,Kropp BP

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the reliability and validity of the Premature Ejaculation Profile (PEP), a self-reported outcome instrument for evaluating domains of PE and its treatment, comprised of four single-item measures, a profile, and an index score. SUBJECTS AND METHODS:Data were from men participating in observational...

journal_title：BJU international

authors： Patrick DL,Giuliano F,Ho KF,Gagnon DD,McNulty P,Rothman M

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:To analyze pathological and short-term oncological outcomes in men undergoing open and minimally-invasive radical prostatectomy (MIRP) for high-risk prostate cancer (HRPC; prostate-specific antigen level [PSA] >20 ng/mL, ≥ cT2c, Gleason score 8-10) in a contemporaneous series. PATIENTS AND METHODS:In total,...

journal_title：BJU international

authors： Pierorazio PM,Mullins JK,Eifler JB,Voth K,Hyams ES,Han M,Pavlovich CP,Bivalacqua TJ,Partin AW,Allaf ME,Schaeffer EM

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:To explain differences over time between operative approach and surgeon type for adrenal surgery in the USA. PATIENTS AND METHODS:A retrospective cohort analysis was performed on all patients undergoing adrenalectomy between 2002 and 2011 using the Nationwide Inpatient Sample. Patients undergoing concurrent ...

journal_title：BJU international

authors： Monn MF,Calaway AC,Mellon MJ,Bahler CD,Sundaram CP,Boris RS

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:To assess whether baseline health-related quality of life (HRQOL) and psychosocial profiles differ in patients with prostate cancer scheduled for radical prostatectomy (RP) or external radiation therapy (ERT), as there is evidence that HRQOL is influenced by psychosocial factors (PFs), so that any variation a...

journal_title：BJU international

authors： Van Andel G,Visser AP,Hulshof MC,Horenblas S,Kurth KH

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:To determine the effect of combined finasteride and flutamide therapy on haemoglobin and haematocrit values in men with advanced prostate cancer. PATIENTS AND METHODS:Nineteen men, previously untreated by hormone therapy, with histologically confirmed adenocarcinoma of the prostate and clinical evidence of a...

journal_title：BJU international

authors： Ornstein DK,Beiser JA,Andriole GL

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:To evaluate contrast-enhanced ultrasonography (US) using cadence-contrast pulse sequencing (CPS) technology, compared with systematic biopsy for detecting prostate cancer, as grey-scale US has low sensitivity and specificity for detecting prostate cancer. PATIENTS AND METHODS:In all, 44 men with suspicious p...

journal_title：BJU international

authors： Aigner F,Pallwein L,Mitterberger M,Pinggera GM,Mikuz G,Horninger W,Frauscher F

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:To describe the surgical technique of transcorporal artificial urinary sphincter (AUS) implantation. To assess the efficacy of the AUS on continence and erectile function. PATIENTS AND METHODS:A prospective evaluation was conducted between December 2007 and October 2012 at a tertiary referral centre of all ...

journal_title：BJU international

authors： Wiedemann L,Cornu JN,Haab E,Peyrat L,Beley S,Cathelineau X,Haab F

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:To critically review published data on the urogynaecological aspects of female sexual dysfunction (FSD), as FSD is a developing multidisciplinary issue associated with several biological, medical and psychological factors. METHODS:The reported prevalence of FSD is 19-50% and women with lower urinary tract sy...

journal_title：BJU international

authors： Dalpiaz O,Kerschbaumer A,Mitterberger M,Pinggera GM,Colleselli D,Bartsch G,Strasser H

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVES:To examine patterns of care among women with urogenital fistula treated in the English National Health Service (NHS) between 2000 and 2009. To assess whether failure of repair was associated with hospital or surgeon workload. PATIENTS AND METHODS:We conducted a retrospective cohort study using data from Hos...

journal_title：BJU international

authors： Cromwell D,Hilton P

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy of OnabotulinumtoxinA (BTXA) injections in men with drug-refractory non-neurogenic overactive bladder (NNOAB). PATIENTS AND METHODS:A total of 43 men received BTXA injections for NNOAB from 2004 to 2012. Patient Global Impression of Improvement (PGI-I) score was obtained. For men with ...

journal_title：BJU international

authors： Habashy D,Losco G,Tse V,Collins R,Chan L

更新日期：2015-10-01 00:00:00

abstract：:OBJECTIVE • To evaluate a novel technique to lower positive surgical margin rates while preserving as much of the neurovascular bundles as possible during nerve-sparing robotic prostatectomy. MATERIALS AND METHODS • In situ intraoperative frozen section (IFS) was performed during robotic-assisted laparoscopic prostate...

journal_title：BJU international

authors： Lavery HJ,Xiao GQ,Nabizada-Pace F,Mikulasovich M,Unger P,Samadi DB

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the prevalence of comorbidity among patients with prostate cancer in relation to tumour and patient characteristics and to assess if comorbidity was a determining factor in the treatment choice for patients with localized prostate cancer. PATIENTS AND METHODS:Serious comorbidity was recorded in t...

journal_title：BJU international

authors： Post PN,Kil PJ,Hendrikx AJ,Janssen-Heijnen ML,Crommelin MA,Coebergh JW

更新日期：1999-10-01 00:00:00

abstract：:Study Type - Therapy (case series) Level of Evidence 4 What's known on the subject? and What does the study add? The resection of the distal ureter and its orifice is an oncological principle during radical nephroureterectomy which is based on the fact that it represents a part of the urinary tract exposed to a consid...

journal_title：BJU international

authors： Phé V,Cussenot O,Bitker MO,Rouprêt M

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To explore the possibility that allogeneic responses might, by chance, encompass cross-reactive T cell clones specific for neo-antigenic tumour determinants, and thereby activate antitumour immunity; such cross-reactions are well documented for antiviral immunity, and genetic instability in developing cancers...

journal_title：BJU international

authors： Muir G,Rajbabu K,Callen C,Fabre JW

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVES:To assess the safety and feasibility of early single-dose mitomycin C (MMC) bladder instillation after robot-assisted radical nephroureterectomy (RARNU) at a tertiary kidney cancer centre. RARNU with bladder cuff excision and subsequent MMC bladder instillation to reduce recurrence risk is the 'gold standard...

journal_title：BJU international

authors： Gulamhusein A,Silva P,Cullen D,Tran M,Mumtaz F,Patki P,Barod R,Bex A

更新日期：2020-12-01 00:00:00

abstract：:Patients with metastatic bone disease often have severe bone pain and debilitating skeletal complications. Zoledronic acid is the only bisphosphonate shown to be safe and effective in reducing skeletal-related events (SREs), including pathological fractures, spinal cord compression, and radiation or surgery to bone in...

journal_title：BJU international

authors： Saad F,Lipton A

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:To determine the level of malondialdehyde (MDA), an indirect indicator of lipid peroxidation-induced injury by reactive oxygen species, in testicular biopsy specimens from infertile patients with and without varicocele. PATIENTS AND METHODS:Levels of MDA were measured in the testicular biopsy specimens from ...

journal_title：BJU international

authors： Köksal IT,Tefekli A,Usta M,Erol H,Abbasoglu S,Kadioglu A

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:To identify the likelihood of finding one or more positive lymph nodes (LNs) according to the number of LNs removed at radical cystectomy (RC), as the number of LNs removed affects disease progression and survival after RC. PATIENTS AND METHODS:Between 1984 and 2003, 731 assessable patients had RC and bilate...

journal_title：BJU international

authors： Capitanio U,Suardi N,Shariat SF,Lotan Y,Palapattu GS,Bastian PJ,Gupta A,Vazina A,Schoenberg M,Lerner SP,Sagalowsky AI,Karakiewicz PI

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:To illustrate the ultrastructural fibre composition of the rat cavernosal nerve at serial levels, from its origin in the main pelvic ganglion to its termination in the corpus cavernosum of the distal penile shaft, and to develop a technique that permits repeated electrophysiological recording from the fibres ...

journal_title：BJU international

authors： Schaumburg HH,Zotova E,Cannella B,Raine CS,Arezzo J,Tar M,Melman A

更新日期：2007-04-01 00:00:00