Establishing the role of cytokine therapy in advanced renal cell carcinoma.

abstract：OBJECTIVE:To evaluate the effect of hypoxia-inducible factor-1alpha (HIF-1alpha) over-expression on the invasion-associated proteins in human prostate cancer cells, as HIF-1alpha is a transcriptional factor that could activate genes involved in the response to hypoxia, but might also enhance the invasive potency of pro...

journal_title：BJU international

authors： Luo Y,He DL,Ning L,Shen SL,Li L,Li X,Zhau HE,Chung LW

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To develop and validate an in vitro method suitable for the quantitative investigation of the growth of calcium oxalate stones through to a clinically significant size. MATERIALS AND METHODS:Small fragments of calcium oxalate calculi were suspended in a mixed suspension/mixed product removal crystalliser sup...

journal_title：BJU international

authors： Ananth K,Kavanagh JP,Walton RC,Rao PN

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of castration on the expression of endothelins (ETs), ET receptors and ET converting enzyme-1 (ECE-1) in the rat seminal vesicle (RSV). MATERIALS AND METHODS:Sprague-Dawley rats (3 months old) were surgically castrated or sham-operated, and then killed 7 days after surgery. Biochem...

journal_title：BJU international

authors： Takahashi W,Yono M,Wada Y,Ikeda K,Weiss RM,Latifpour J

更新日期：2003-11-01 00:00:00

abstract：UNLABELLED:Study Type--Therapy (cohort) Level of Evidence 2a. What's known on the subject? and What does the study add? Despite expanding treatment options for castration-resistant prostate cancer (CRPC), therapies with long response duration remain intangible due to prostate cancer cells' natural ability to develop it...

journal_title：BJU international

authors： Nakabayashi M,Werner L,Courtney KD,Buckle G,Oh WK,Bubley GJ,Hayes JH,Weckstein D,Elfiky A,Sims DM,Kantoff PW,Taplin ME

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To assess the results of transperitoneal laparoscopic pelvic lymphadenectomy as a separate staging procedure in patients with early prostate cancer. PATIENTS AND METHODS:The results were reviewed from the first 27 patients with prostate cancer admitted for laparoscopic lymphadenectomy between January 1994 an...

journal_title：BJU international

authors： Shackley DC,Irving SO,Brough WA,O'Reilly PH

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVES:To comprehensively investigate the role of the N6 -methyladenosine (m6 A) erasers ALKBH5 and FTO in clear cell renal cell carcinoma (ccRCC), other RCC subtypes, and oncocytoma with respect to prognostic value and biomarker potential. PATIENTS AND METHODS:The collection of tissue samples was performed within...

journal_title：BJU international

authors： Strick A,von Hagen F,Gundert L,Klümper N,Tolkach Y,Schmidt D,Kristiansen G,Toma M,Ritter M,Ellinger J

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:To isolate new cDNAs corresponding to genes whose expression is increased during castration-induced rat prostate apoptosis. MATERIALS AND METHODS:Differential display of mRNAs from 3-day castrated and normal rat ventral prostates was used to identify differentially expressed clones. Northern blots were hybri...

journal_title：BJU international

authors： Bruyninx M,Ammar H,Reiter E,Cornet A,Closset J

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:To compare the cost-effectiveness of surgery and topical steroids as treatments for phimosis (defined as a clinically verifiable, pathological, cicatricial stenosis of the prepuce) and to evaluate the financial basis of these treatments. METHODS:Data on treatment using topical steroids was obtained from publ...

journal_title：BJU international

authors： Berdeu D,Sauze L,Ha-Vinh P,Blum-Boisgard C

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:To study the effect of smoking on bladder cancer presentation and outcome in a large cystectomy population. PATIENTS AND METHODS:A database including 546 patients from the University Health Network (Toronto, Canada) and Turku University Hospital (Turku, Finland) was studied. In addition to the association of...

journal_title：BJU international

authors： Boström PJ,Alkhateeb S,Trottier G,Athanasopoulos PZ,Mirtti T,Kortekangas H,Laato M,van Rhijn B,van der Kwast T,Fleshner NE,Jewett MA,Finelli A,Zlotta AR

更新日期：2012-01-01 00:00:00

abstract：UNLABELLED:Study Type - Therapy (outcomes) Level of Evidence 2b What's known on the subject? and What does the study add? Data on the oncological outcomes in patients undergoing salvage cystectomy for recurrent disease following bladder-sparing treatment is limited and mostly based on case reports. We present the clini...

journal_title：BJU international

authors： Bruins HM,Wopat R,Mitra AP,Cai J,Miranda G,Skinner EC,Daneshmand S

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVES:To evaluate the relative merits of robotically assisted partial nephrectomy (RPN), using a matched-pair analysis, with laparoscopic PN (LPN). PATIENTS AND METHODS:Between July 2006 and August 2007, 12 patients had RPN for tumour; the outcomes were compared retrospectively with 12 matched patients who had LP...

journal_title：BJU international

authors： Aron M,Koenig P,Kaouk JH,Nguyen MM,Desai MM,Gill IS

更新日期：2008-07-01 00:00:00

abstract：UNLABELLED:Study Type - Therapy (cohort) Level of Evidence 2b What's known on the subject? and What does the study add? Selective destruction of targeted prostate tissue is now technically feasible. Much has been theorized but little is known about the proper patient selection or treatment outcomes to determine if this...

journal_title：BJU international

authors： Ward JF,Jones JS

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To investigate the effectiveness of a combined treatment of 3-30-methylene-bis[4-hydroxycoumarin] (dicoumarol) with doxorubicin for the treatment of urothelial cancer, as doxorubicin is a common chemotherapeutic agent but its therapeutic efficacy is limited. MATERIALS AND METHODS:The synergistic effect of di...

journal_title：BJU international

authors： Matsui Y,Watanabe J,Ding S,Nishizawa K,Kajita Y,Ichioka K,Saito R,Kobayashi T,Ogawa O,Nishiyama H

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:To investigate whether ureteroscopy (URS) before radical nephroureterectomy (RNU) for upper tract urothelial carcinomas (UTUCs) has an impact on oncological outcomes. PATIENTS AND METHODS:We performed a systematic literature search of PubMed, Web of Science, and EMBASE for citations published prior to Septe...

journal_title：BJU international

authors： Guo RQ,Hong P,Xiong GY,Zhang L,Fang D,Li XS,Zhang K,Zhou LQ

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of MN-001, a novel orally active anti-inflammatory agent, in suppressing the bladder hyperactivity resulting from ovalbumin (OA)-induced mast-cell stimulation in a rat model. MATERIALS AND METHODS:Sprague-Dawley rats of both sexes were divided into five groups of 10 each, with group 1...

journal_title：BJU international

authors： Rajasekaran M,Locke KW,Parsons CL

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVES:To describe the most recent data from phase I and II clinical trials of stereotactic body radiation therapy (SBRT) using image-guided robotic radiosurgery, specifically the Cyberknife(®) (Accuracy Incorporated, Sunnyvale, CA, USA). To better determine thecurrent role of this type of radiosurgery in prostate ...

journal_title：BJU international

authors： Seisen T,Drouin SJ,Phé V,Parra J,Mozer P,Bitker MO,Cussenot O,Rouprêt M

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:To measure dihydropyrimidine dehydrogenase (DPD), an enzyme involved in the metabolism of 5-fluorouracil (5-FU), expression in prostate cancer and determine whether 5-chloro-2,4-dihydroxypyridine (CDHP), a potent inhibitor of DPD, enhances the antitumoral activity of 5-FU against prostate cancer. PATIENTS, M...

journal_title：BJU international

authors： Li Y,Mizutani Y,Shiraishi T,Nakamura T,Mikami K,Takaha N,Okihara K,Kawauchi A,Sakai T,Miki T

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVES:To report an audit of preoperative staging variables, case selection, stage migration and prostate-specific antigen (PSA) recurrence at five large centres in the south of England. To establish PSA outcome values after radical prostatectomy for clinically localized prostate cancer in the UK, and enable approp...

journal_title：BJU international

authors： Winkler MH,Khan FA,Hoh IM,Okeke AA,Sugiono M,McInerney P,Boustead GB,Persad R,Kaisary AV,Gillatt DA

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the role of urine cytology in the investigation of men with lower urinary tract symptoms (LUTS) in the absence of haematuria. PATIENTS AND METHODS:The study comprised 336 men attending a LUTS assessment clinic, who had neither macroscopic nor microscopic haematuria. One sample of urine was collec...

journal_title：BJU international

authors： Potter JM,Quigley M,Pengelly AW,Fawcett DP,Malone PR

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:To analyse the technical details and the long-term results of laparoscopic ureterolithotomy. PATIENTS AND METHODS:Laparoscopic ureterolithotomy was undertaken in 101 patients between 1991 and 2001; in only one patient with retroperitoneal fibrous adhesions was the procedure transperitoneal, being retroperito...

journal_title：BJU international

authors： Gaur DD,Trivedi S,Prabhudesai MR,Madhusudhana HR,Gopichand M

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:To study scrotal microvascularization and apply the findings to the design of reliable skin flaps for reconstructive surgery of complex urethral or panurethral stenoses. MATERIALS AND METHODS:In 15 cryopreserved male cadavers, scrotal skin vascularization was explored using macro- and microdissections, and t...

journal_title：BJU international

authors： Carrera A,Gil-Vernet A,Forcada P,Morro R,Llusa M,Arango O

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:To determine the changes in body composition, muscle function and energy expenditure after radical cystectomy (RC). PATIENTS AND METHODS:Eleven consecutive men (median age 66 years, range 44-79) who had a RC over a 1-year period had measurements made of their total body protein, by neutron-activation analysi...

journal_title：BJU international

authors： Mathur S,Plank LD,Hill AG,Rice MA,Hill GL

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:To review long-term oncological and functional outcomes of testicular-sparing surgery (TSS) in men presenting with bilateral or monorchide testicular tumours at one of five reference centres for testicular neoplasm and infertility. PATIENTS AND METHODS:We review 25 cases of bilateral synchrone and metachrone...

journal_title：BJU international

authors： Ferretti L,Sargos P,Gross-Goupil M,Izard V,Wallerand H,Huyghe E,Rigot JM,Durand X,Benoit G,Ferriere JM,Droupy S

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVES:To compare the results of retroperitoneal laparoscopic with open partial nephroureterectomy. PATIENTS AND METHODS:Laparoscopic retroperitoneal partial nephroureterectomy was undertaken in 15 children (13 upper and two lower poles; median age at the time of surgery 61 months, range 5-212). A three-trocar ret...

journal_title：BJU international

authors： El-Ghoneimi A,Farhat W,Bolduc S,Bagli D,McLorie G,Khoury A

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:To evaluate how many patients could have undergone partial nephrectomy (PN) rather than radical nephrectomy (RN) before and after neoadjuvant axitinib therapy, as assessed by five independent urological oncologists, and to study the variability of inter-observer agreement. PATIENTS AND METHODS:Pre- and post-...

journal_title：BJU international

authors： Karam JA,Devine CE,Fellman BM,Urbauer DL,Abel EJ,Allaf ME,Bex A,Lane BR,Thompson RH,Wood CG

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:To describe the surgical management of patients with renal cell carcinoma (RCC) in a solitary kidney (managed preferentially by nephron-sparing surgery, NSS, to avoid dialysis) and extending into the renal vein or inferior vena cava (T3b). PATIENTS AND METHODS:We identified 13 patients treated surgically bet...

journal_title：BJU international

authors： Sengupta S,Zincke H,Leibovich BC,Blute ML

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:To determine the value of gene-expression profiling as a predictor of the status of the regional nodes in patients with penile carcinoma. PATIENTS AND METHODS:Tumour samples of 56 patients with penile squamous cell carcinoma were analysed for the gene expression on 35 k oligoarrays; 32 were from patients wit...

journal_title：BJU international

authors： Kroon BK,Leijte JA,van Boven H,Wessels LF,Velds A,Horenblas S,van't Veer LJ

更新日期：2008-08-01 00:00:00

abstract：UNLABELLED:Study Type - Therapy (economic analysis). LEVEL OF EVIDENCE:1b. OBJECTIVE:To assess and compare the costs and effects value of either starting with sacral neuromodulation (SNM) or botulinum toxin A (BTX) treatment in patients with refractory idiopathic overactive bladder from a societal perspective. MATER...

journal_title：BJU international

authors： Leong RK,de Wachter SG,Joore MA,van Kerrebroeck PE

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVES:To evaluate the possible influence of non-pharmacological interventions, such as compressive bandages and intermittent pneumatic compression (IPC), on leg oedema and nocturnal polyuria (NP), and the possible interrelation between both pathologies in patients with spinal cord injury (SCI), as patients with SC...

journal_title：BJU international

authors： Viaene A,Roggeman S,Goessaert AS,Kessler TM,Mehnert U,Besien VV,De Muynck M,Everaert K

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the clinicopathological outcomes for patients with clinical T2 (cT2) urothelial carcinoma treated with radical cystectomy (RC) without neoadjuvant chemotherapy (NC). PATIENTS AND METHODS:We identified 212 patients with cT2 tumours who underwent RC at our institution without NC. Pathological asses...

journal_title：BJU international

authors： Canter D,Long C,Kutikov A,Plimack E,Saad I,Oblaczynski M,Zhu F,Viterbo R,Chen DY,Uzzo RG,Greenberg RE,Boorjian SA

更新日期：2011-01-01 00:00:00