Abstract:
OBJECTIVE:To aid the interpretation of the trends in prostate cancer mortality, which declined in the UK in the early 1990 s for unknown reasons, by investigating prostate cancer death rates, incidence and treatments in England and Wales in 1975-2004. METHODS:Join-point regression was used to assess secular trends in mortality and incidence (source: Office of National Statistics), radical prostatectomy and orchidectomy (source: Hospital Episode Statistics database) and androgen-suppression drugs (source: Intercontinental Medical Statistics). RESULTS:Prostate cancer mortality declined from 1992 (95% confidence interval, CI, 1990-94). The relative decline in mortality to 2004 was greater and more sustained amongst men aged 55-74 years (annual percentage mortality reduction 2.75%; 95% CI 2.33-3.18%) than amongst those aged >or=75 years (0.71%, 0.26-1.15%). The use of radical prostatectomy increased between 1991 (89 operations) and 2004 (2788) amongst men aged 55-74 years. The prescribing of androgen suppression increased between 1987 (33,000 prescriptions) and 2004 (470,000). CONCLUSIONS:The decrease in prostate cancer mortality was greater amongst men aged 55-74 years than in those aged >or=75 years, but pre-dated the substantial use of prostate-specific antigen screening and radical prostatectomy in the UK. An increase in radical therapy amongst younger groups with localized cancers and screen-detected low-volume locally advanced disease as a result of stage migration, as well as prolonged survival from increased medical androgen suppression therapy, might partly explain recent trends.
journal_name
BJU Intjournal_title
BJU internationalauthors
Hussain S,Gunnell D,Donovan J,McPhail S,Hamdy F,Neal D,Albertsen P,Verne J,Stephens P,Trotter C,Martin RMdoi
10.1111/j.1464-410X.2007.07338.xsubject
Has Abstractpub_date
2008-03-01 00:00:00pages
547-55issue
5eissn
1464-4096issn
1464-410Xpii
BJU7338journal_volume
101pub_type
杂志文章abstract:OBJECTIVE:To determine the acceptability and patient satisfaction of transrectal biopsy undertaken with the patient under sedation. Patients and methods A retrospective questionnaire was sent to 100 patients who had undergone transrectal biopsy between January and August 1998. Levels of patient acceptability and satisf...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2001.02221.x
更新日期:2001-06-01 00:00:00
abstract:OBJECTIVES:To investigate whether ureteroscopy (URS) before radical nephroureterectomy (RNU) for upper tract urothelial carcinomas (UTUCs) has an impact on oncological outcomes. PATIENTS AND METHODS:We performed a systematic literature search of PubMed, Web of Science, and EMBASE for citations published prior to Septe...
journal_title:BJU international
pub_type: 杂志文章,meta分析,评审
doi:10.1111/bju.14053
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:To assess the use of demucosalized ileum for bladder augmentation, following the same principles previously used with the sigmoid colon. PATIENTS AND METHODS:Eleven patients with bladder exstrophy or a neurogenic bladder had their bladders augmented with demucosalized ileum instead of the sigmoid colon, but ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-4096.2001.lima.2465.x
更新日期:2001-11-01 00:00:00
abstract:OBJECTIVE:To investigate the prognostic value of the Gleason score in prostate cancer. PATIENTS AND METHODS:A consecutive series of 305 men with prostate cancer diagnosed at transurethral resection (1975-1990) and with no curative treatment was analysed. There was no assessment of prostate-specific antigen level durin...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2002.02669.x
更新日期:2002-04-01 00:00:00
abstract::While patient age and gender are important factors in the clinical decision-making for treating urothelial carcinoma of the bladder (UCB), there are no evidence-based recommendations to guide healthcare professionals. We review previous reports on the influence of age and gender on the incidence, biology, mortality an...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2009.09076.x
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVE:To analyse the performance of the Prostate Cancer Prevention Trial Risk Calculator (PCPT-RC) and two iterations of the European Randomised Study of Screening for Prostate Cancer (ERSPC) Risk Calculator, one of which incorporates prostate volume (ERSPC-RC) and the other of which incorporates prostate volume an...
journal_title:BJU international
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/bju.13437
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:To test the replicability and robustness of findings about urological symptoms in men and women, classified using an objective statistical method, cluster analysis, by planned sensitivity analyses conducted within and across two large, epidemiological studies of lower urinary tract symptoms. METHODS:Sensitiv...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.07653.x
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVES:To: (i) calculate traditional compliance (CTrad) for a normal bladder by DeltaV/DeltaPdet, where DeltaV is the mean volumetric capacity and DeltaPdet is the detrusor pressure rise; (ii) assess its usefulness; (iii) identify the variables that are necessary for correctly assessing bladder compliance; and (iv)...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2004.05054.x
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVE:To report the events during and after radical cystectomy and urinary diversion for bladder cancer, in terms of major and minor complications, comparing a minimal with an extended lymphadenectomy, as more lymph nodes obtained during radical cystectomy may improve staging and thus the outcome. PATIENTS AND MET...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1464-410x.2004.04557.x
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:To study the role of peroperative transrectal ultrasonography (peTRUS) for the dissection of the bladder neck during robot-assisted laparoscopic prostatectomy (RALP). PATIENTS AND METHODS:Integrated peTRUS in the da Vinci S system (Intuitive Surgical, Sunnyvale, CA, USA) was used for bladder neck identificat...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.07830.x
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:To assess psychometrically a new questionnaire for measuring the psychosocial morbidity in patients with prostate cancer and in their partners, and to compare the morbidity of patients and their partners. PATIENTS AND METHODS:A sequential sample of patients with any stage of prostate cancer and attending gen...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2000.00914.x
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVE:To assess the influence of the 2012 US Preventive Services Task Force (USPSTF) recommendation against prostate-specific antigen (PSA)-based screening on oncological and functional outcomes following robot-assisted laparoscopic prostatectomy (RALP). MATERIALS AND METHODS:We retrospectively analysed patients w...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.15051
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVES:To re-evaluate the role of diabetes mellitus (DM) as a risk factor for penile implant infection by exploring the association between glycated haemoglobin (HbA1c) levels and penile implant infection rates and to define a threshold value that predicts implant infection. PATIENTS AND METHODS:We conducted a mul...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/bju.14076
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:To use information from genetic polymorphisms and from patients (drinking/exercise habits) to identify their association with stone disease, the main analytical and predictive tools being discriminant analysis (DA) and artificial neural networks (ANNs). PATIENTS, SUBJECTS AND METHODS:Urinary stone disease is...
journal_title:BJU international
pub_type: 临床试验,杂志文章
doi:10.1046/j.1464-410x.2003.03067.x
更新日期:2003-05-01 00:00:00
abstract:UNLABELLED:Study Type - Therapy (RCT) Level of Evidence 1b What's known on the subject? and What does the study add? Men with prostate cancer have higher rates of non-cancer mortality and CV morbidity and some of that excess risk has been attributed to the treatment they receive. ADT is an established treatment option ...
journal_title:BJU international
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1464-410X.2011.10555.x
更新日期:2012-05-01 00:00:00
abstract::Lower urinary tract symptoms (LUTS), benign prostatic obstruction (BPO), and the overactive bladder have increasing prevalence with age in both men and women (with the obvious exception). The question is, are they interrelated or independently related to age? The specific issue is whether BPO causes the overactive bla...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410x.2000.tb16953.x
更新日期:2000-05-01 00:00:00
abstract:OBJECTIVE:To determine the incidence of detrusor instability (DI) detected by conventional and ambulatory bladder pressure monitoring, any link between urodynamic findings before and after colposuspension, and between patients' symptoms and the urodynamic findings. PATIENTS AND METHODS:Sixty-five patients, scheduled t...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.1999.00390.x
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVE:To assess the changing distribution of stage in seminoma and nonseminomatous germ cell tumours (NSGCTs), as recent reports contained no detailed information on pT stage and vascular invasion, important factors in the decision for further treatment. PATIENTS AND METHODS:Histopathological reports from 1976 to ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2006.06424.x
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVES:To evaluate the possible influence of non-pharmacological interventions, such as compressive bandages and intermittent pneumatic compression (IPC), on leg oedema and nocturnal polyuria (NP), and the possible interrelation between both pathologies in patients with spinal cord injury (SCI), as patients with SC...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.14672
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVE:To determine any bias by authors of different nationalities in their citation rate of selected urological journals in papers published in the British Journal of Urology and the Journal of Urology. METHODS:Using a simple computer program and text files of accepted reports in the BJU, or those available on CD-...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.1999.00267.x
更新日期:1999-10-01 00:00:00
abstract:INTRODUCTION:To prospectively evaluate the accuracy of transvesical contrast-enhanced ultrasound (CEUS) as an alternative method for the detection of anastomotic leakage after radical retropubic prostatectomy (RRP) in comparison with the current standard method of conventional retrograde cystography (CG). PATIENTS AND...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09497.x
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVE:To report the management of urachal anomalies using a robotically assisted approach. PATIENTS AND METHODS:Between January 2005 and February 2006, five patients (mean age 51 years, range 24-68) were diagnosed with urachal anomalies. Two basic robot-assisted surgical approaches were used for excising the urach...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2006.06430.x
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVE:To determine whether very small prostate cancers present in patients who also have lymph node (LN) metastases represent a particularly aggressive disease variant compared with larger LN-positive tumours. PATIENTS AND METHODS:We identified 37 501 patients diagnosed with prostate cancer between 1988 and 2001 t...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13248
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:To compare the effects of diuresis induced by a loop diuretic (frusemide), an osmotic diuretic (mannitol) and a high-osmolar radio-contrast medium (sodium iothalamate) on the intrarenal resistive index (RI) in dogs with chronic unilateral partial ureteric obstruction (UPUO). MATERIALS AND METHODS:The split r...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2002.02830.x
更新日期:2002-07-01 00:00:00
abstract:OBJECTIVE:To explore whether a panel of kallikrein markers in blood: total, free and intact prostate-specific antigen (PSA) and kallikrein-related peptidase 2, could be used as a non-invasive alternative for predicting prostate cancer on biopsy in a screening setting. SUBJECTS AND METHODS:The study cohort comprised pr...
journal_title:BJU international
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1464-410X.2012.11690.x
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:To assess the outcomes for patients with Gleason score 8-10 prostate cancer treated with brachytherapy, external beam radiotherapy (EBRT) and hormonal therapy (HT). PATIENTS AND METHODS:In all, 181 patients with Gleason scores 8-10 prostate cancer were treated from 1994 to 2006 with a (103)Pd implant (prescr...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2009.08661.x
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVES:To investigate if absorption of irrigation fluid occurs during bipolar plasma vaporisation (BPV) of the prostate. To examine the clinical predictors of increased risk of fluid absorption and to assess if changes in serum electrolytes, venous pH, haemoglobin or haematocrit are able to detect intra-operative f...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12170
更新日期:2013-09-01 00:00:00
abstract:UNLABELLED:Study Type - Therapy (case series). LEVEL OF EVIDENCE:4. OBJECTIVE:To evaluate the results in terms of functional results and morbidity of Z-shaped ileal neobladder performed in a single center. PATIENTS AND METHODS:329 consecutive male patients who had an orthotopic bladder replacement using the Z-shaped...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.10000.x
更新日期:2011-08-01 00:00:00
abstract::Men receiving androgen-deprivation therapy will in time develop metastatic castrate-resistant prostate cancer (mCRPC). Whilst effective treatment options for mCRPC have traditionally been limited, new agents are becoming available. Since 2010, the number and class of agents available to treat mCRPC has increased drama...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/bju.12736
更新日期:2015-03-01 00:00:00
abstract::A detailed history, physical examination, symptom and quality-of-life assessment, and urine analysis are unanimously considered essential components of the initial evaluation of urinary incontinence. Beyond these assessments, there are no universally accepted recommendations and, to date, imaging is not recommended in...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2005.05433.x
更新日期:2005-04-01 00:00:00