The Simplified PADUA REnal (SPARE) nephrometry system: a novel classification of parenchymal renal tumours suitable for partial nephrectomy.

Abstract:

OBJECTIVE:To simplify the original Preoperative Aspects and Dimensions Used for an Anatomical (PADUA) classification of renal tumours, generating a new system able to predict equally or better the risk of overall complications in patients undergoing partial nephrectomy (PN); and to test if the addition of the contact surface area (CSA) parameter improves the accuracy of the original PADUA and new Simplified PADUA REnal (SPARE) nephrometry classification systems. PATIENTS AND METHODS:We analysed the clinical records of 531 patients who underwent PN (open, laparoscopic and robot-assisted) for renal tumours at five tertiary academic referral centres from January 2014 to December 2016. The ability of each variable included in the PADUA classification to predict overall complications was tested using binary logistic regression analysis. The variables that were not statistically significant were excluded from the SPARE classification. In addition to the original PADUA and SPARE systems, another two models were generated adding tumour CSA. Receiver operating characteristic curve analysis was used to compare the ability of the four different models to predict overall complications. Binary logistic regression was used to perform both univariable and multivariable analyses looking for predictors of postoperative complications. Linear regression analysis was used to identify independent predictors of absolute change in estimated glomerular filtration rate (eGFR; ACE). RESULTS:The SPARE nephrometry score system including: (i) rim location, (ii) renal sinus involvement, (iii) exophytic rate, and (iv) tumour dimension; showed equal performance in comparison with the original PADUA score (area under the curve [AUC] 0.657 vs 0.664). Adding tumour CSA to the original PADUA (AUC 0.661) or to the SPARE (AUC 0.658) scores did not increase the accuracy of either system to predict overall complications. The SPARE system (odds ratio 1.2, 95% confidence interval 1.1-1.3) was an independent predictor of postoperative overall complications. Age (P < 0.001), body mass index (P < 0.001), Charlson Comorbidity Index (P = 0.02), preoperative eGFR (P < 0.001), and tumour CSA (P = 0.005) were independent predictors of ACE. Limitations include the retrospective design and the lack of central imaging review. CONCLUSIONS:The new SPARE score is comprised of only four variables instead of the original six and its accuracy to predict overall complications is similar to that of the original PADUA score. Addition of tumour CSA was not associated with an increase in prognostic accuracy. The SPARE system could replace the original PADUA score to evaluate the complexity of tumours suitable for PN.

journal_name

BJU Int

journal_title

BJU international

authors

Ficarra V,Porpiglia F,Crestani A,Minervini A,Antonelli A,Longo N,Novara G,Giannarini G,Fiori C,Simeone C,Carini M,Mirone V

doi

10.1111/bju.14772

subject

Has Abstract

pub_date

2019-04-09 00:00:00

eissn

1464-4096

issn

1464-410X

pub_type

杂志文章
  • The effect of age and gender on bladder cancer: a critical review of the literature.

    abstract::While patient age and gender are important factors in the clinical decision-making for treating urothelial carcinoma of the bladder (UCB), there are no evidence-based recommendations to guide healthcare professionals. We review previous reports on the influence of age and gender on the incidence, biology, mortality an...

    journal_title:BJU international

    pub_type: 杂志文章,评审

    doi:10.1111/j.1464-410X.2009.09076.x

    authors: Shariat SF,Sfakianos JP,Droller MJ,Karakiewicz PI,Meryn S,Bochner BH

    更新日期:2010-02-01 00:00:00

  • Comparison of oncological outcomes of transperitoneal and retroperitoneal laparoscopic radical nephrectomy for the management of clear-cell renal cell carcinoma: a multi-institutional study.

    abstract:OBJECTIVE:• To investigate the oncological efficacy of retroperitoneal laparoscopic radical nephrectomy (RLRN) compared with transperitoneal laparoscopic radical nephrectomy (TLRN) for the management of clear-cell renal cell carcinoma (RCC). PATIENTS AND METHODS:• With emphasis on survival and disease recurrence, a re...

    journal_title:BJU international

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1464-410X.2010.09636.x

    authors: Ha US,Hwang TK,Kim YJ,Oh TH,Jeon YS,Lee W,Lim JS,Lee TY,Choi Y,Park SK,Byun SS

    更新日期:2011-05-01 00:00:00

  • Salvage cystectomy after failure of interstitial radiotherapy and external beam radiotherapy for bladder cancer.

    abstract:OBJECTIVE:To evaluate the long-term results of salvage cystectomy after interstitial radiotherapy (IRT) and external beam radiotherapy (EBRT) for transitional cell carcinoma, and to assess the morbidity and functional results of the different urinary diversions used. PATIENTS AND METHODS:The records of 27 patients tre...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2004.05034.x

    authors: Nieuwenhuijzen JA,Horenblas S,Meinhardt W,van Tinteren H,Moonen LM

    更新日期:2004-10-01 00:00:00

  • Anatomical studies of the neurovascular bundle and cavernosal nerves.

    abstract:OBJECTIVE:To accurately define the anatomy of the neurovascular bundle (NVB) in men. MATERIALS AND METHODS:The NVB was microdissected in detail bilaterally in 12 fixed human male adult cadavers. The anatomy of the NVB and its relationship to surrounding pelvic structures was ascertained in each specimen. RESULTS:Prev...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2004.05106.x

    authors: Costello AJ,Brooks M,Cole OJ

    更新日期:2004-11-01 00:00:00

  • A prospective study of the short-term quality-of-life outcomes of patients undergoing transperineal prostate biopsy.

    abstract:OBJECTIVE:To investigate in a prospective, observational study whether transperineal prostate biopsy (TPbx) results in patient-reported quality-of-life (QoL) changes from baseline in the first 3-months after TPbx. PATIENTS AND METHODS:Consenting patients completed the 26-item Expanded Prostate cancer Index Composite (...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.13413

    authors: Dowrick AS,Wootten AC,Howard N,Peters JS,Murphy DG

    更新日期:2016-07-01 00:00:00

  • In vivo accumulation of different hypericin ion pairs in the urothelium of the rat bladder.

    abstract:OBJECTIVE:To optimise the diagnostic and phototherapeutic efficacy of hypericin in superficial bladder cancer, by developing a bladder instillation fluid that does not depend on the presence of plasma proteins for an appropriate and reliable urothelial uptake of hypericin. MATERIALS AND METHODS:Sodium hypericinate (in...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2005.05316.x

    authors: Huygens A,Kamuhabwa AR,van Cleynenbreugel B,van Poppel H,Roskams T,de Witte PA

    更新日期:2005-02-01 00:00:00

  • Technical and equipment challenges for laparoendoscopic single-site surgery and natural orifice transluminal endoscopic surgery.

    abstract::Laparoendoscopic single-site surgery (LESS) and natural orifice transluminal endoscopic surgery (NOTES™) are new approaches to minimally invasive surgery. A number of technical challenges need to be overcome and new developments of equipment are required before widespread acceptance of either modality occurs. In this ...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2010.09665.x

    authors: Sawyer MD,Ponsky LE

    更新日期:2010-09-01 00:00:00

  • Mortality associated with Fournier's gangrene remains unchanged over 25 years.

    abstract:OBJECTIVES:To report a case series of Fournier's gangrene (FG) from our institution, and to investigate its mortality over the past 25 years. PATIENTS AND METHODS:Case notes of men presenting to our institution from 2013 to 2016 with FG were reviewed. As well as age, diabetic history, length of stay, length of stay in...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.14998

    authors: Radcliffe RS,Khan MA

    更新日期:2020-04-01 00:00:00

  • Indications for and complications of pelvic lymph node dissection in prostate cancer: accuracy of available nomograms for the prediction of lymph node invasion.

    abstract:OBJECTIVES:To externally validate the currently available nomograms for predicting lymph node invasion (LNI) in patients with prostate cancer (PCa) and to assess the potential risk of complications of extended pelvic lymph node dissection (ePLND) when using the recommended threshold. METHODS:A total of 14 921 patients...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.15220

    authors: Oderda M,Diamand R,Albisinni S,Calleris G,Carbone A,Falcone M,Fiard G,Gandaglia G,Marquis A,Marra G,Parola C,Pastore A,Peltier A,Ploussard G,Roumeguère T,Sanchez-Salas R,Simone G,Smelzo S,Witt JH,Gontero P

    更新日期:2020-09-01 00:00:00

  • Purification of human muscle-derived cells using an immunoselective method for potential use in urological regeneration.

    abstract:OBJECTIVE:To purify human muscle-derived cells (hMDCs) that could be used for managing urinary incontinence, erectile dysfunction and for bladder reconstitution. MATERIALS AND METHODS:hMDCs isolated by a modified preplate technique (MPT) from skeletal muscles of limbs were purified by CD34 antibody and magnetic Dynabe...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2009.09032.x

    authors: Lu SH,Yang AH,Chen KK,Chiang HS,Chang LS

    更新日期:2010-06-01 00:00:00

  • Systematic review and network meta-analysis on the relative efficacy of osteoporotic medications: men with prostate cancer on continuous androgen-deprivation therapy to reduce risk of fragility fractures.

    abstract::Androgen-deprivation therapy (ADT) is an effective treatment for men with advanced prostate cancer, but loss of bone mineral density (BMD) is a major risk factor for fractures. This review compared the efficacy of available treatments to provide prescribing guidance to healthcare professionals. This is the first revie...

    journal_title:BJU international

    pub_type: 杂志文章,评审

    doi:10.1111/bju.14015

    authors: Poon Y,Pechlivanoglou P,Alibhai SMH,Naimark D,Hoch JS,Papadimitropoulos E,Hogan ME,Krahn M

    更新日期:2018-01-01 00:00:00

  • A randomized, double-blind, placebo-controlled study of the efficacy and safety of bupropion for treating hypoactive sexual desire disorder in ovulating women.

    abstract:OBJECTIVE:To compare the efficacy of sustained-release (SR) bupropion to placebo in treating hypoactive sexual desire disorder (HSDD) in ovulating women. PATIENTS AND METHODS:After a 1-week, placebo lead-in phase, 232 treatment-seeking women with regular menstrual cycles were randomly assigned to bupropion SR 150 mg/d...

    journal_title:BJU international

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1464-410X.2010.09208.x

    authors: Safarinejad MR,Hosseini SY,Asgari MA,Dadkhah F,Taghva A

    更新日期:2010-09-01 00:00:00

  • Comparison of the bladder tumour antigen test with photodynamic diagnosis in patients with pathologically confirmed recurrent superficial urinary bladder tumours.

    abstract:OBJECTIVE:To verify the sensitivity of the bladder tumour antigen (BTAstat, Bard Urological, Covington, GA) test against the sensitive procedure of photodynamic diagnosis (PDD), in which 5-aminolaevulinic acid (5-ALA, a precursor of fluorescent porphyrins) is absorbed by the tumour and detected by ultraviolet cystoscop...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1046/j.1464-410x.2002.02717.x

    authors: Lipinski M,Jeromin L

    更新日期:2002-05-01 00:00:00

  • Validation of serum C-reactive protein (CRP) as an independent prognostic factor for disease-free survival in patients with localised renal cell carcinoma (RCC).

    abstract:OBJECTIVE:To validate high-sensitivity C-reactive protein (hs-CRP) serum levels as an independent marker for disease-free survival (DFS) in clinically localised clear cell renal cell carcinoma (ccRCC). PATIENTS AND METHODS:In all, 403 consecutive patients with clinically localised (T1-3N0M0) ccRCC treated by radical o...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.12067

    authors: de Martino M,Klatte T,Seemann C,Waldert M,Haitel A,Schatzl G,Remzi M,Weibl P

    更新日期:2013-06-01 00:00:00

  • Fourteen-year oncological and functional outcomes of high-intensity focused ultrasound in localized prostate cancer.

    abstract:UNLABELLED:WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: High-intensity focused ultrasound (HIFU) is an alternative treatment option for localized prostate cancer (PCa), which is applied for over 15 years. There are conflicting recommendations for HIFU among urological societies, which can be explained by ...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2012.11715.x

    authors: Ganzer R,Fritsche HM,Brandtner A,Bründl J,Koch D,Wieland WF,Blana A

    更新日期:2013-08-01 00:00:00

  • Prognostic factors for and outcome of locally advanced prostate cancer after radical prostatectomy.

    abstract:OBJECTIVE:To present the outcomes of cT3N0M0 prostate cancer after radical prostatectomy (RP) and determine the prognostic factors in biochemical progression-free survival (BPFS), clinical progression-free survival (CPFS), cancer-specific survival (CSS) and overall survival (OS) after long-term follow-up of 10 years. ...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2009.09054.x

    authors: Hsu CY,Wildhagen MF,Van Poppel H,Bangma CH

    更新日期:2010-06-01 00:00:00

  • Ureteric embolization with stainless-steel coils for managing refractory lower urinary tract fistula: a 12-year experience.

    abstract:OBJECTIVE:To report our 12-year experience with radiological treatment (ureteric embolization) for refractory urinary fistula, as malignancy, radiation therapy, and/or chronic inflammation increase the risk of lower urinary tract fistula after surgical urinary diversion, which can lead to significant morbidity, and for...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2006.06569.x

    authors: Shindel AW,Zhu H,Hovsepian DM,Brandes SB

    更新日期:2007-02-01 00:00:00

  • Delayed therapy with curative intent in a contemporary prostate cancer watchful-waiting cohort.

    abstract:OBJECTIVE:To identify predictors of delayed therapy with curative intent, an increasingly common option in contemporary patients with prostate cancer who initially choose watchful waiting. PATIENTS AND METHODS:The characteristics of all patients at one institution and diagnosed with T1-4NXM0 prostate cancer between 19...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410x.2003.04669.x

    authors: el-Geneidy M,Garzotto M,Panagiotou I,Hsieh YC,Mori M,Peters L,Klein T,Beer TM

    更新日期:2004-03-01 00:00:00

  • Causes of renal forniceal rupture.

    abstract:UNLABELLED:What's known on the subject? and What does the study add? Renal forniceal rupture is a common finding in patients with ureteral obstruction. It is thought to be due to increased renal pelvis pressure from backup of urine, causing one or more renal fornices to leak urine. This phenomenon has not been systemat...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2011.10164.x

    authors: Gershman B,Kulkarni N,Sahani DV,Eisner BH

    更新日期:2011-12-01 00:00:00

  • Pelvic exenteration surgery in patients with locally advanced castration-naïve and castration-resistant, symptomatic prostate cancer.

    abstract:OBJECTIVES:To evaluate retrospectively the surgical, symptomatic and oncological outcomes of pelvic exenteration surgery (PES) in men with significant intrapelvic complications of locally advanced castration-sensitive (CSPC) and castration-resistant prostate cancer (CRPC). PATIENTS AND METHODS:A total of 103 patients ...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.15088

    authors: Heidenreich A,Bludau M,Bruns C,Nestler T,Porres D,Pfister DJKP

    更新日期:2020-09-01 00:00:00

  • Transfusion rates after 800 Aquablation procedures using various haemostasis methods.

    abstract:OBJECTIVE:To determine if athermal methods are as effective in preventing blood transfusions as the use of cautery across various prostate volumes following prostate tissue resection for benign prostatic hyperplasia using Aquablation. PATIENTS AND METHODS:The current commercial AQUABEAM robot that performs Aquablation...

    journal_title:BJU international

    pub_type: 杂志文章,多中心研究

    doi:10.1111/bju.14990

    authors: Elterman D,Bach T,Rijo E,Misrai V,Anderson P,Zorn KC,Bhojani N,El Hajj A,Chughtai B,Desai M

    更新日期:2020-04-01 00:00:00

  • Severity categories of the International Prostate Symptom Score before, and urinary morbidity after, permanent prostate brachytherapy.

    abstract:OBJECTIVE:To determine if the International Prostate Symptom Score (IPSS) before seed implantation, stratified into mild (0-7), moderate (8-19) and severe (>20) categories, predicts brachytherapy-related morbidity in terms of IPSS resolution, catheter dependency and the need for surgical intervention after brachytherap...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2006.05887.x

    authors: Gutman S,Merrick GS,Butler WM,Wallner KE,Allen Z,Galbreath RW,Adamovich E

    更新日期:2006-01-01 00:00:00

  • Face, content, construct and concurrent validity of dry laboratory exercises for robotic training using a global assessment tool.

    abstract:OBJECTIVES:To evaluate robotic dry laboratory (dry lab) exercises in terms of their face, content, construct and concurrent validities. To evaluate the applicability of the Global Evaluative Assessment of Robotic Skills (GEARS) tool to assess dry lab performance. MATERIALS AND METHODS:Participants were prospectively c...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.12559

    authors: Ramos P,Montez J,Tripp A,Ng CK,Gill IS,Hung AJ

    更新日期:2014-05-01 00:00:00

  • Cryoablation of small renal masses: assessment of the outcome at one institution.

    abstract:OBJECTIVE:To report our 5-year experience with laparoscopic and percutaneous cryoablation (LCA and PCA) for managing small renal masses. PATIENTS AND METHODS:We retrospectively analysed patients undergoing LCA and PCA between October 2000 and March 2006 at our institution. After approval from the Institutional Review ...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2007.07158.x

    authors: Bandi G,Wen CC,Hedican SP,Moon TD,Lee FT Jr,Nakada SY

    更新日期:2007-10-01 00:00:00

  • Nocturia in the Dutch adult population.

    abstract:OBJECTIVE:To estimate the prevalence of nocturia in the Dutch adult population, its association with sociodemographic and health characteristics, and to assess problems experienced by persons with nocturia. SUBJECTS AND METHODS:In spring 2001 a telephone survey was conducted among a representative sample of 4721 Dutch...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1046/j.1464-410x.2002.03011.x

    authors: van Dijk L,Kooij DG,Schellevis FG

    更新日期:2002-11-01 00:00:00

  • Positive surgical margins are a risk factor for significant biochemical recurrence only in intermediate-risk disease.

    abstract:UNLABELLED:What's known on the subject? and What does the study add? Positive surgical margins (PSMs) after radical prostatectomy are common, although their impact on the risk of disease recurrence is unknown. We examined the impact of PSMs on the risk of 'significant' biochemical recurrence stratified by their risk of...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2011.10868.x

    authors: Corcoran NM,Hovens CM,Metcalfe C,Hong MK,Pedersen J,Casey RG,Peters J,Harewood L,Goldenberg SL,Costello AJ,Gleave ME

    更新日期:2012-09-01 00:00:00

  • The conservative management of corynebacterium group D2 encrusted pyelitis.

    abstract:OBJECTIVE:To evaluate the conservative management of encrusted pyelitis (EP), an infectious disease caused by urea-splitting micro-organisms (Corynebacterium group D2 being the most common), and characterized by stone encrustation of the collecting system. PATIENTS AND METHODS:Four patients (aged 17-62 years) with EP ...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1046/j.1464-410x.1999.00156.x

    authors: Meria P,Desgrippes A,Fournier R,Arfi C,Antoine C,Martinat L,Teillac P,Le Duc A

    更新日期:1999-08-01 00:00:00

  • Early observations of the effect of extracorporeal shockwave lithotripsy on blood pressure: a prospective randomized control clinical trial.

    abstract:OBJECTIVE:To determine, in a randomized controlled clinical trial, the effect of extracorporeal shock wave lithotripsy (ESWL) on blood pressure. PATIENTS AND METHODS:The trial included 228 patients with small (< 15 mm) asymptomatic calyceal stones who were randomised to undergo ESWL (113 patients) or to an untreated (...

    journal_title:BJU international

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1464-410x.2000.00571.x

    authors: Elves AW,Tilling K,Menezes P,Wills M,Rao PN,Feneley RC

    更新日期:2000-04-01 00:00:00

  • Improvements in benign prostatic hyperplasia-specific quality of life with dutasteride, the novel dual 5alpha-reductase inhibitor.

    abstract:OBJECTIVES:To examine the effect of the dual-action 5alpha-reductase inhibitor dutasteride on benign prostatic hyperplasia (BPH)-specific health status, as measured by the BPH Impact Index (BII), and to identify baseline and treatment risk factors for those most bothered by their BPH symptoms at the end of the protocol...

    journal_title:BJU international

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1464-410x.2003.04310.x

    authors: O'Leary MP,Roehrborn C,Andriole G,Nickel C,Boyle P,Höfner K

    更新日期:2003-08-01 00:00:00

  • Transperineal template prostate-mapping biopsies: an evaluation of different protocols in the detection of clinically significant prostate cancer.

    abstract:OBJECTIVES:To determine whether modified transperineal template prostate-mapping (TTPM) biopsy protocols, altering the template or the biopsy density, have sensitivity and negative predictive value (NPV) equal to full 5-mm TTPM. PATIENTS AND METHODS:Retrospective analysis of an institutional registry including treatme...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.13306

    authors: Valerio M,Anele C,Charman SC,van der Meulen J,Freeman A,Jameson C,Singh PB,Emberton M,Ahmed HU

    更新日期:2016-09-01 00:00:00