Abstract:
OBJECTIVE:To develop a rat model of erectile dysfunction (ED) after cavernous nerve injury. MATERIALS AND METHODS:Given the great similarity between the anatomical structure of the cavernous nerve in rats and humans, 24 rats underwent dissections and the cavernous nerves were identified with the aid of an operating microscope. Then the rats were randomized into two groups: sham-operated controls and a bilateral cavernous nerve section group. At 3 months after surgery, the rats were evaluated for their response to an apomorphine challenge. RESULTS:The erectile response after an apomorphine challenge was normal in all the control rats, while there were no erections in the bilateral injured group. CONCLUSION:The rat major autonomic ganglion and its cavernous nerve can be identified with the aid of a microscope. Rats are inexpensive and easy to handle, thus a good animal for developing an ED model of cavernous nerve injury. In the present study, the rats with cavernous nerve injury lost erectile capacity in a reliable and reproducible fashion. Because of the great similarity between the cavernous nerve of rats and humans, one may consider this technique as a reliable experimental model for studying ED after radical prostatectomy.
journal_name
BJU Intjournal_title
BJU internationalauthors
Kaufmann O,Claro J,Cury J,Andrade E,Longo B,Aguiar W,Mello L,Srougi Mdoi
10.1111/j.1464-410X.2008.07760.xsubject
Has Abstractpub_date
2008-09-01 00:00:00pages
1026-8issue
8eissn
1464-4096issn
1464-410Xpii
BJU7760journal_volume
102pub_type
杂志文章abstract:OBJECTIVE:• To systematically review the literature on gemcitabine chemotherapy for advanced or metastatic bladder cancer. MATERIALS AND METHODS:• The Medical Literature Analysis and Retrieval System Onlinedatabase (MEDLINE), the Excerpta Medicadatabase (EMBASE), the Cumulative Index to Nursing and Allied Health Liter...
journal_title:BJU international
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1464-410X.2011.10341.x
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVES:To report a case series of Fournier's gangrene (FG) from our institution, and to investigate its mortality over the past 25 years. PATIENTS AND METHODS:Case notes of men presenting to our institution from 2013 to 2016 with FG were reviewed. As well as age, diabetic history, length of stay, length of stay in...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.14998
更新日期:2020-04-01 00:00:00
abstract::To assess the evidence for the concept that the androgen receptor of prostate cancer (PCa) cells becomes saturated when testosterone values exceed castrate levels, so that testosterone administration in hypogonadal men with untreated PCa does not stimulate tumour growth. To propose basic criteria for administration of...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2011.10193.x
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:• To analyse the overall and type-specific human papillomavirus (HPV) prevalence and distribution in penile carcinoma and determine the correlation to histopathological parameters. PATIENTS AND METHODS:• In this retrospective study, we analysed HPV status in 241 patients with penile carcinoma, treated at Öre...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09770.x
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:To determine the long-term results of constructing a sigmoid neobladder after radical cystectomy for transitional cell carcinoma (TCC) of the urinary bladder. PATIENTS AND METHODS:The study included 170 patients with TCC of the bladder and a normal sigmoid colon. After radical cystectomy the neobladder was f...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2006.06541.x
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVE:To assess the relationship between the histological features of renal chromophobe cell carcinoma (CCC) and clinical outcome in patients with renal cell carcinoma. PATIENTS AND METHODS:From 1957 to 1996, 41 patients with CCC of the kidney (4.9% of all kidney carcinomas) were treated at our university hospital...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2002.02977.x
更新日期:2002-10-01 00:00:00
abstract:OBJECTIVE:To obtain community-based information about the incidence of interstitial cystitis, a chronic disabling condition of the bladder where knowledge is limited because there are no definitive diagnostic criteria. PATIENTS AND METHODS:All residents of Olmsted County, MN, USA who had received a physician-assigned ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2003.04060.x
更新日期:2003-02-01 00:00:00
abstract:OBJECTIVE:To devise a procedure capable of curing complicated ureteric strictures and replacing segments of lost ureter, without the long-term infective complications of bowel interposition or the surgical magnitude of autotransplantation. PATIENTS AND METHODS:Four patients with complicated strictures and one with seg...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.1999.00019.x
更新日期:1999-05-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/bju.13928
更新日期:2017-11-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2006.06102.x
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVES:To investigate histopathologically the beneficial effects of Panax ginseng extract on guinea pig testes damaged by 2,3, 7,8-tetrachlorodibenzo-p-dioxin (TCDD). MATERIALS AND METHODS:Ninety guinea pigs were divided into six equal groups. The normal controls (group 1) received vehicle and saline; group 2 rece...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.1999.00046.x
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVES:To study the patterns of care of penile cancer diagnosed in the state of New South Wales (NSW) over a 10 year period and determine factors that are associated with differences in survival. PATIENTS AND METHODS:All invasive penile cancer diagnosed between 2001 and 2009 in NSW, Australia, were identified from...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13626
更新日期:2016-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/bju.12688
更新日期:2015-02-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.1999.00865.x
更新日期:1999-01-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2012.11618.x
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:To assess the impact on patterns of recurrence of adjuvant chemotherapy in patients with stage 1 nonseminomatous germ cell tumours (NSGCT) of the testis, who have a high likelihood of relapse on surveillance if certain risk factors are identified in the orchidectomy specimen, and thus the theoretical need for...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2000.00722.x
更新日期:2000-07-01 00:00:00
abstract::What's known on the subject? and What does the study add? With recent improvements in the prognosis for patients with metastatic renal cell carcinoma (mRCC), focus is now shifting towards maximising clinical benefit from targeted therapies. Factors other than efficacy data are increasingly being considered when select...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2012.11100.x
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVES:To analyze pathological and short-term oncological outcomes in men undergoing open and minimally-invasive radical prostatectomy (MIRP) for high-risk prostate cancer (HRPC; prostate-specific antigen level [PSA] >20 ng/mL, ≥ cT2c, Gleason score 8-10) in a contemporaneous series. PATIENTS AND METHODS:In total,...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.11757.x
更新日期:2013-10-01 00:00:00
abstract::Lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH) is a slowly progressing disease, with some patients progressing more rapidly than others. In 80% of patients who progress this is caused by the worsening of symptoms. The physician can predict the risk of progression from the patient's ...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2005.05488.x
更新日期:2005-06-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.11340.x
更新日期:2013-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/bju.12262
更新日期:2014-02-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2011.10283.x
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:To obtain a greater understanding of sexual behaviour and habits among men with and without erectile dysfunction (ED), and their female partners, to improve the management of ED in heterosexual men. SUBJECTS AND METHODS:A population-based study was conducted amongst men and women aged > 40 years. None of the...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410x.2003.04684.x
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVE:To present the results of endopyelotomy using endoluminal ultrasonography (EUS) to identify crossing vessels, as the success rates of endopyelotomy are generally lower than pyeloplasty, especially in patients with crossing vessels. PATIENTS AND METHODS:Forty-one consecutive patients who underwent EUS before ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2003.04103.x
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVES:To describe the natural history of prostate cancer in men who experience a second biochemical recurrence (BCR) after salvage radiotherapy (SRT) after prostatectomy. PATIENTS AND METHODS:After undergoing SRT at one of two institutions between 1986 and 2013, 286 patients experienced a second BCR, defined as t...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/bju.13926
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the prevalence of comorbidity among patients with prostate cancer in relation to tumour and patient characteristics and to assess if comorbidity was a determining factor in the treatment choice for patients with localized prostate cancer. PATIENTS AND METHODS:Serious comorbidity was recorded in t...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.1999.00279.x
更新日期:1999-10-01 00:00:00
abstract::OBJECTIVE To evaluate the indications for penile prosthesis implantation in the treatment of erectile dysfunction (ED) before and after the introduction of sildenafil. PATIENTS AND METHODS Penile prosthesis implantation was indicated in 144 men with ED at our institution between 1992 and 2007; 83 (55.6%) accepted the ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2009.08356.x
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVES:To present our initial operative experience in which single-port-light endoscopic robot-assisted reconstructive and extirpative urological surgery was performed by one surgeon, using a pig model. MATERIALS AND METHODS:This pilot study was conducted in male farm pigs to determine the feasibility and safety o...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2009.08955.x
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the oncological outcomes of patients with specimen Gleason 8 and 9 prostate cancers and to determine factors that predict biochemical recurrence-free survival (BCRFS) after robot-assisted radical prostatectomy (RARP). PATIENTS AND METHODS:Of 4156 patients who underwent RARP from January 2001 to 2...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09484.x
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVE:•To evaluate the natural history of patients presenting with positive urinary cytology in the absence of clinically identifiable disease. PATIENTS AND METHODS:•A surgical database was queried to identify 48 patients with positive urinary cytology of undetermined source. •All patients underwent a thorough uro...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2011.10210.x
更新日期:2011-10-01 00:00:00