Panax ginseng protects the testis against 2,3,7, 8-tetrachlorodibenzo-p-dioxin induced testicular damage in guinea pigs.

abstract：OBJECTIVE:•To determine the optimal treatment for incidentally detected small renal masses between radical nephrectomy, partial nephrectomy, ablative therapy (AT) and active surveillance (AS) using a decision-analytic Markov model. SUBJECTS AND METHODS:•The reference case was an otherwise healthy 60-year-old patient. ...

journal_title：BJU international

authors： Abouassaly R,Yang S,Finelli A,Kulkarni GS,Alibhai SM

更新日期：2011-10-01 00:00:00

abstract：:Advanced adrenal carcinoma remains a significant therapeutic challenge, with conventional approaches to systemic therapy having failed to achieve sustained objective remissions or major survival benefit in most instances. Several systemic therapies, including mitotane, suramin and gossypol, as well as cytotoxic agents...

journal_title：BJU international

authors： Costa R,Wesolowski R,Raghavan D

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:To investigate the effectiveness of a combined treatment of 3-30-methylene-bis[4-hydroxycoumarin] (dicoumarol) with doxorubicin for the treatment of urothelial cancer, as doxorubicin is a common chemotherapeutic agent but its therapeutic efficacy is limited. MATERIALS AND METHODS:The synergistic effect of di...

journal_title：BJU international

authors： Matsui Y,Watanabe J,Ding S,Nishizawa K,Kajita Y,Ichioka K,Saito R,Kobayashi T,Ogawa O,Nishiyama H

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:To compare the effectiveness and safety of standard percutaneous nephrolithotomy (sPCNL) and super-mini PCNL (SMP). PATIENTS AND METHODS:A total of 150 patients presenting with renal calculi of <2 cm were randomised to either sPCNL (Group 1) or SMP (Group 2). Randomisation was based on centralised computer-g...

journal_title：BJU international

authors： Guddeti RS,Hegde P,Chawla A,de la Rosette JJMCH,Laguna Pes MP,Kapadia A

更新日期：2020-08-01 00:00:00

abstract：UNLABELLED:What's known on the subject? and What does the study add? Protein kinase C inhibitor (PKCI) can decrease glomerular and tubular cell apoptosis and mitosis and attenuate collagen accumulation and fibronectin expression in a PUUO rat model. Although the role of PKC has been well studied in diabetic nephropathy...

journal_title：BJU international

authors： Juan YS,Chuang SM,Long CY,Lin RJ,Liu KM,Wu WJ,Huang CH

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVES:To describe the surgical technique of transcorporal artificial urinary sphincter (AUS) implantation. To assess the efficacy of the AUS on continence and erectile function. PATIENTS AND METHODS:A prospective evaluation was conducted between December 2007 and October 2012 at a tertiary referral centre of all ...

journal_title：BJU international

authors： Wiedemann L,Cornu JN,Haab E,Peyrat L,Beley S,Cathelineau X,Haab F

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:To examine the tissue expression of DNA topoisomerase I (Topo I) and IIalpha (Topo II), to pursue the possibility of future chemotherapy regimens for squamous cell carcinoma of the penis (SCCP), as high expression of Topo I might indicate sensitivity to the camptothecins, whereas high Topo II might indicate s...

journal_title：BJU international

authors： Berney DM,Stankiewicz E,Adlan AM,Kudahetti S,Biedrzycki OJ,Hadway P,Watkin N,Corbishley C

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:To investigate the high circumcision rate in South Korea and its rapid increase in the short period since its introduction. SUBJECTS AND METHODS:From January to December 2000, 5434 South Korean males (or their parents) aged 0-92 years were interviewed in detail about their circumcision status, their age at c...

journal_title：BJU international

authors： Pang MG,Kim DS

更新日期：2002-01-01 00:00:00

abstract：:What's known on the subject? and What does the study add? With recent improvements in the prognosis for patients with metastatic renal cell carcinoma (mRCC), focus is now shifting towards maximising clinical benefit from targeted therapies. Factors other than efficacy data are increasingly being considered when select...

journal_title：BJU international

authors： Bex A,Gore M,Mulders P,Sternberg CN

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVES:To report the 2-year clinical and biochemical follow-up of symptomatic men who had a high prostate-specific-antigen (PSA) level, for whom our policy has been to avoid biopsy in those with a normal repeat PSA, as minimizing negative prostate biopsies is an important goal in managing men with a high PSA, where...

journal_title：BJU international

authors： Singh R,Cahill D,Popert R,O'Brien TS

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:To report the outcomes of >1000 men with low-risk prostate cancer treated with low-dose-rate (LDR) brachytherapy at three large UK cancer centres. PATIENTS AND METHODS:A total of 1038 patients with low-risk prostate cancer (prostate-specific antigen [PSA] ≤10 ng/mL, Gleason score 6, ≤T2b disease) were treate...

journal_title：BJU international

authors： Dickinson PD,Malik J,Mandall P,Swindell R,Bottomley D,Hoskin P,Logue JP,Wylie JP

更新日期：2014-05-01 00:00:00

abstract：:Data from the Japanese Urological Society showed that, in Japan, almost half of patients with localized prostate cancer are treated with hormone therapy (HT), regardless of disease stage, and that radiation therapy (RT) is also widely used to treat high-risk patients. A retrospective study was undertaken in Japan to e...

journal_title：BJU international

authors： Mizokami A,Ueno S,Fukagai T,Ito K,Ehara H,Kinbara H,Origasa H,Usami M,Namiki M,Akaza H

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of zoledronic acid (ZA) in osteoporotic patients with prostate cancer receiving either luteinizing hormone-releasing hormone agonists (LHRHA, which accelerate bone loss) or bicalutamide (which preserves bone mineral density, BMD) as androgen-deprivation therapy is the mainstay of trea...

journal_title：BJU international

authors： Wadhwa VK,Weston R,Parr NJ

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:• To determine (i) the presence of fatty acid amide hydrolase (FAAH) in the urinary bladder; (ii) whether or not endogenous fatty acid ethanolamides are synthesized by the bladder; (iii) the effects of FAAH inhibition on referred hyperalgesia associated with acute bladder inflammation in rats. MATERIALS AND ...

journal_title：BJU international

authors： Merriam FV,Wang ZY,Hillard CJ,Stuhr KL,Bjorling DE

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:To identify significant prognostic indicators of upper urinary tract (UUT) urothelial carcinoma (UC) and to assess a risk stratification of patients. PATIENTS AND METHODS:We retrospectively analysed data from 162 patients with non-metastatic UC primarily occurring in UUT treated with open nephroureterectomy....

journal_title：BJU international

authors： Simone G,Papalia R,Loreto A,Leonardo C,Sentinelli S,Gallucci M

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVES:To investigate the effect of patient age on the stone-free rate (SFR) in patients with urinary calculi treated by extracorporeal shockwave lithotripsy (ESWL). PATIENTS AND METHODS:In all, 2192 solitary radio-opaque urinary stones of 5-15 mm were identified in adult patients receiving primary ESWL. Patients ...

journal_title：BJU international

authors： Ng CF,Wong A,Tolley D

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:To determine if a decrease in oestrogen (E) levels increases activity in bladder afferent nerves, by investigating the effects of E loss on afferent nerve activity in ovariectomized (OVX) rats, and making comparisons with findings in ageing female rats. MATERIALS AND METHODS:Female Sprague-Dawley rats were d...

journal_title：BJU international

authors： Aizawa N,Iijima K,Rosenbaum JS,Downs TR,Igawa Y,Andersson KE,Wyndaele JJ

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To assess the prevalence of obstructive sleep apnoea (OSA) in men presenting with erectile dysfunction (ED) at a single centre. PATIENTS AND METHODS:All men attending a specialised andrology outpatient department with a new diagnosis of ED were included in this prospective study. All patients completed three...

journal_title：BJU international

authors： Kalejaiye O,Raheem AA,Moubasher A,Capece M,McNeillis S,Muneer A,Christopher AN,Garaffa G,Ralph DJ

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:To assess the utility of percentage free/total prostate-specific antigen (f/tPSA) levels for detecting prostate cancer in a prospectively screened population of men with a 'normal' total PSA level. PATIENTS AND METHODS:Men aged 50-65 years were contacted via their general practitioner and invited for prostat...

journal_title：BJU international

authors： Rowe EW,Laniado ME,Walker MM,Patel A

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:To critically review published data on the urogynaecological aspects of female sexual dysfunction (FSD), as FSD is a developing multidisciplinary issue associated with several biological, medical and psychological factors. METHODS:The reported prevalence of FSD is 19-50% and women with lower urinary tract sy...

journal_title：BJU international

authors： Dalpiaz O,Kerschbaumer A,Mitterberger M,Pinggera GM,Colleselli D,Bartsch G,Strasser H

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVES:To present the oncological and functional outcomes of salvage focal (SFC) and salvage total (STC) cryoablation for recurrent prostate cancer (PCa) after failed primary radiotherapy. PATIENTS AND METHODS:From March 2003 to August 2010, 50 men with biopsy-proven unilateral (n = 25) or bilateral (n = 25) radio...

journal_title：BJU international

authors： de Castro Abreu AL,Bahn D,Leslie S,Shoji S,Silverman P,Desai MM,Gill IS,Ukimura O

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To report our experience of using laparoscopy for the accurate location and simultaneous removal of small dysplastic kidneys with ectopic ureteric insertion causing urinary incontinence and that were not detected by conventional imaging modalities. PATIENTS AND METHODS:Seven girls (mean age 7.9 years, range ...

journal_title：BJU international

authors： Yeung CK,Liu KW,Ng WT,Tan HL,Tam YH,Lee KH

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:• To present a novel method of renal ablation using direct current electrolysis, using a porcine model to assess the safety and efficacy of the technique. MATERIALS AND METHODS:• In all, 20 anaesthetised pigs were used, after receiving ethical approval. The pigs were housed and managed in accordance with Ins...

journal_title：BJU international

authors： Lloyd M,Miller J,Moretti KL,Texler M,Maddern GJ

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVES:To evaluate if the obesity paradox, wherein obesity portends worse overall prognosis for a disease but improved outcomes for patients receiving immunotherapy, exists for patients receiving bacillus Calmette-Guérin (BCG) in a contemporary cohort. PATIENTS AND METHODS:We performed an Institutional Review Boar...

journal_title：BJU international

authors： Brooks NA,Kokorovic A,Xiao L,Matulay JT,Li R,Ranasinghe WKB,Nagaraju S,Shen Y,Gao J,Navai N,Dinney CPN,Grossman HB,Kamat AM

更新日期：2020-11-14 00:00:00

abstract：OBJECTIVE:To determine if there is a significant difference in outcomes of clinical trials funded by industry or not of antimuscarinic medications used to treat overactive bladder (OAB) symptoms and detrusor overactivity (DOA). METHODS:A Medline search was conducted from January 1966 to June 2003 to identify human cli...

journal_title：BJU international

authors： Tulikangas PK,Ayers A,O'Sullivan DM

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:• To investigate the role of c-kit-positive interstitial cells (ICCs) in mediating muscarinic receptor-induced phasic contractions of isolated bladder strips from streptozotocin(STZ)-induced diabetic rats and to confirm the expression and location of ICCs in the rat bladder. MATERIALS AND METHODS:• Bladders ...

journal_title：BJU international

authors： Vahabi B,McKay NG,Lawson K,Sellers DJ

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVES:To assess the oucomes of penile prosthesis (PP) implantation after total phallic reconstruction secondary to gender dysphoria. PATIENTS AND METHODS:We conducted a retrospective single-centre analysis of 247 consecutive patients. The recruitment period was January 2001 to October 2015. A total of 328 inflata...

journal_title：BJU international

authors： Falcone M,Garaffa G,Gillo A,Dente D,Christopher AN,Ralph DJ

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To assess the influence of the 2012 US Preventive Services Task Force (USPSTF) recommendation against prostate-specific antigen (PSA)-based screening on oncological and functional outcomes following robot-assisted laparoscopic prostatectomy (RALP). MATERIALS AND METHODS:We retrospectively analysed patients w...

journal_title：BJU international

authors： Seetharam Bhat KR,Moschovas MC,Onol FF,Sandri M,Rogers T,Roof S,Rocco B,Patel VR

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:• To assess the feasibility of radical prostatectomy (RP) in a series of patients with prostate cancer with very high prostate-specific antigen (PSA) levels by comparing the clinical outcomes of different PSA thresholds (20.1-50 ng/mL, 50.1-100 ng/mL and >100 ng/mL, respectively). PATIENTS AND METHODS:• With...

journal_title：BJU international

authors： Gontero P,Spahn M,Tombal B,Bader P,Hsu CY,Marchioro G,Frea B,Van Der Eeckt K,Kneitz B,Frohneberg D,Tizzani A,Van Poppel H,Joniau S

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:• To study the operability and effectiveness of a biodegradable ureteral stent for clinical treatment of ureteral war injury using a canine model. MATERIALS AND METHODS:• A device was designed and employed to generate firearm fragment wounds in unilateral ureters (on randomly chosen sides) of nine beagles (G...

journal_title：BJU international

authors： Li G,Wang ZX,Fu WJ,Hong BF,Wang XX,Cao L,Xu FQ,Song Q,Cui FZ,Zhang X

更新日期：2011-09-01 00:00:00